Heavy Quark Parameters and Vcb from Spectral Moments in Semileptonic B Decays

We extract the heavy quark masses and non-perturbative parameters from the Delphi preliminary measurements of the first three moments of the charged lepton energy and hadronic mass distributions in semileptonic B decays, using a multi-parameter fit. We adopt two formalisms, one of which does not rely on a 1/mc expansion and makes use of running quark masses. The data are consistent and the level of accuracy of the experimental inputs largely determines the present sensitivity. The results allow to improve on the uncertainty in the extraction of Vcb.Comment: 13 pages, 2 figure

EuroSpine Task Force on Research: support for spine researchers

In recognition of the value of research to the practice of spine care, Federico Balagué and Ferran Pellisé, at the time President and Secretary for EuroSpine, asked Margareta Nordin to set up a Task Force on Research (TFR) for EuroSpine during summer 2011. The concept was to stimulate and facilitate a research community within the society, through two main functions: (1) distribution of EuroSpine funds to researchers; (2) develop and deliver research training/education courses. What has the EuroSpine TFR accomplished since its inception

Numerical Investigations of Oscillons in 2 Dimensions

Oscillons, extremely long-living localized oscillations of a scalar field, are studied in theories with quartic and sine-Gordon potentials in two spatial dimensions. We present qualitative results concentrating largely on a study in frequency space via Fourier analysis of oscillations. Oscillations take place at a fundamental frequency just below the threshold for the production of radiation, with exponentially suppressed harmonics. The time evolution of the oscillation frequency points indirectly to a life time of at least 10 million oscillations. We study also elliptical perturbations of the oscillon, which are shown to decay. We finish by presenting results for boosted and collided oscillons, which point to a surprising persistence and soliton-like behaviour.Comment: Matches the published version (12 pages, 34 figures

Three-dimensional printing for restoration of the donor face : A new digital technique tested and used in the first facial allotransplantation patient in Finland

Background and aims: Prosthetic mask restoration of the donor face is essential in current facial transplant protocols. The aim was to develop a new three-dimensional (3D) printing (additive manufacturing; AM) process for the production of a donor face mask that fulfilled the requirements for facial restoration after facial harvest. Materials and methods: A digital image of a single test person's face was obtained in a standardized setting and subjected to three different image processing techniques. These data were used for the 3D modeling and printing of a donor face mask. The process was also tested in a cadaver setting and ultimately used clinically in a donor patient after facial allograft harvest. Results: and Conclusions: All the three developed and tested techniques enabled the 3D printing of a custom-made face mask in a timely manner that is almost an exact replica of the donor patient's face. This technique was successfully used in a facial allotransplantation donor patient. (C) 2016 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.Peer reviewe

Bird Communities and Feeding Guilds From Three Land Use Types in Kerian River Basin, Perak

The objectives of this study were to determine the current bird species present in the study areas and to analyze variation of feeding guilds in different habitat types. Point count and mist-netting methods were used for bird census in SF and OP, while only point count method was used in PF. Feeding guilds were determined for each species recorded. A total of 183 species representing 49 families were recorded at all study sites. Secondary forest scored 106 species, followed by PF with 70 species and OP with 58 species. The highest abundance of bird families observed in SF was Pycnonotidae (26.65%), Hemiprocnidae (19.77%) and Muscicapidae (7.10%); in OP, Pycnonotidae (21.59%), Muscicapidae (19.12%) and Sturnidae (17.95%); in PF, Ardeidae (29.09%), Sturnidae (10.15%) and Hirundinidae (7.86%). Alternative hypothesis established that the abundance of species is different across habitat types, F(2,105) = 99.83, p < 0.05. Eight feeding guilds were identified in paddy field and seven in both secondary forest and oil palm plantation. If forests were converted to OP feeding guild could possibly change with a decreased in insectivore, insectivore-frugivore, insectivore-nectarivore and frugivore species; and increased in carnivore, grainivore and omnivore species. If forests were converted to PF feeding guild could possibly change with a decreased in insectivore, insectivore-frugivore and frugivore species; and increased in carnivore, insectivorenectarivore, insectivore-grainivore, grainivore and omnivore species. Comparison between SF and OP with Mann-Whitney U-test showed significant differences in six feeding guilds, including insectivore, insectivore-frugivore, insectivore-nectarivore, frugivore, grainivore and omnivore. Comparison between SF and PF showed significant differences in five feeding guilds, comprising of carnivore, insectivore-grainivore, frugivore, grainivore and omnivore. Comparison between OP and PF showed all feeding guilds to be significantly different. Complex vegetation in forestoffers more niches, with higher plant and insect diversity to support more bird species. In contrast, PF, a temporary wetland, support predominantly various waterbirds and migratory species

Cerebrospinal fluid cytokines in Lyme neuroborreliosis

Background: Lyme neuroborreliosis (LNB) is one of the manifestations of Lyme disease. Although it is known that immune reaction of LNB patients is dominated by Th1 and Th2 responses and patients have elevated numbers of B cells in their cerebrospinal fluid (CSF), not all the cells involved in inflammation and cytokine secretion have been characterized. The current diagnostics of LNB is based on intrathecal production of antibodies. In recent years, the measurement of chemokine CXCL13 concentration from the CSF has been introduced as a new promising diagnostic tool for LNB to complement the antibody-based diagnostic methods. A few other cytokines have also been analyzed as possible diagnostic markers. However, multiplex analyses simultaneously evaluating the concentrations of a large number of different cytokines in the CSF of LNB patients have been lacking thus far. Extensive cytokine profiling CSF samples of LNB patients would also help in understanding the complex immunopathogenesis of LNB.Methods: CSF samples were analyzed from 43 LNB patients, 19 controls, 18 tick-borne encephalitis patients, and 31 multiple sclerosis patients. In addition, CSF samples from 23 LNB patients obtained after the antibiotic treatment were examined. Altogether, the concentrations of 49 different cytokines were determined from all of the samples. The concentrations of 48 different cytokines were analyzed by magnetic bead suspension array using the Bio-Plex Pro Human Cytokine 21- and 27-plex panels, and the concentration of CXCL13 was analyzed by an ELISA based method.Results: Distinct cytokine profiles which were able to distinguish LNB patients from controls, tick-borne encephalitis patients, multiple sclerosis patients, and LNB patients treated with antibiotics were identified. LNB patients had elevated concentrations of all major T helper cell type cytokines (Th1, Th2, Th9, Th17, and Treg) in their CSF.Conclusions: Despite the great differences in the CSF cytokine profiles of different patient groups, CXCL13 still remained as the best marker for LNB. However, IL-1ra might also be helpful as a marker for the antibiotic treatment response. Concerning the immunopathogenesis, this is the first report suggesting the involvement of Th9 cells in the immune response of LNB

Main Clinical Use of Additive Manufacturing (Three-Dimensional Printing) in Finland Restricted to the Head and Neck Area in 2016-2017

Background and Aims: Additive manufacturing or three-dimensional printing is a novel production methodology for producing patient-specific models, medical aids, tools, and implants. However, the clinical impact of this technology is unknown. In this study, we sought to characterize the clinical adoption of medical additive manufacturing in Finland in 2016-2017. We focused on non-dental usage at university hospitals. Materials and Methods: A questionnaire containing five questions was sent by email to all operative, radiologic, and oncologic departments of all university hospitals in Finland. Respondents who reported extensive use of medical additive manufacturing were contacted with additional, personalized questions. Results: Of the 115 questionnaires sent, 58 received answers. Of the responders, 41% identified as non-users, including all general/gastrointestinal (GI) and vascular surgeons, urologists, and gynecologists; 23% identified as experimenters or previous users; and 36% identified as heavy users. Usage was concentrated around the head area by various specialties (neurosurgical, craniomaxillofacial, ear, nose and throat diseases (ENT), plastic surgery). Applications included repair of cranial vault defects and malformations, surgical oncology, trauma, and cleft palate reconstruction. Some routine usage was also reported in orthopedics. In addition to these patient-specific uses, we identified several off-the-shelf medical components that were produced by additive manufacturing, while some important patient-specific components were produced by traditional methodologies such as milling. Conclusion: During 2016-2017, medical additive manufacturing in Finland was routinely used at university hospitals for several applications in the head area. Outside of this area, usage was much less common. Future research should include all patient-specific products created by a computer-aided design/manufacture workflow from imaging data, instead of concentrating on the production methodology.Peer reviewe

Psoas abscess ten years after ipsilateral nephrectomy for pyonephrosis

Pyogenic abscess of the psoas muscle is a rare disease. The Authors report a recently observed case which developed 10 years after ipsilateral nephrectomy for pyonephrosis, reviewing the pertinent literature. The culture of the pus extracted only reproduced Proteus mirabilis. The relation between psoas abscess and nephrectomy is unclear. To make diagnosis is important to consider this condition in differential diagnosis in presence of fever and flank tenderness in a nephrectomized patient

Residual stress investigation on Ti-48Al-2Cr-2Nb samples produced by Electron Beam Melting process

Ti-48Al-2Cr-2Nb (Ti-48-2-2) is an intermetallic alloy belonging to a family of gamma-TiAl intermetallic alloys that are attracting significant attention. Electron Beam Melting (EBM) process is today the only manufacturing process that allows effective production of parts made by these kinds of alloys. Proper process control avoids high temperatures in the surrounding areas that may generate significant residual stresses that could cause micro-cracks. In this paper, an investigation on the residual stress state on Ti-48-2-2 parts is carried out using the hole drilling method. In particular, the influence of EBM process parameters is evaluated in order to understand the effects of the residual stresses on part integrity