526 research outputs found
Finding out If It Is True: Comparing Mediation and Negotiation through Research
In this article, we first use existing research evidence to contextualize more clearly the place of civil case mediation in the litigation process. When we understand civil mediation as part of adversarial litigation - rather than as distinct from it - we see the importance of comparing mediation and unassisted negotiation. Next, we discuss research and commentary on the barriers to negotiation and the ways in which mediation might help overcome them. This work provides a more pragmatic and empirically grounded perspective on the potential value of mediation than does mediation ideology and suggests a wide range of hypotheses to guide future research. Finally, we reexamine briefly the research about preferences for mediation and the modest body of existing studies that do contrast litigant experiences with mediation and unaided negotiation in the context of litigation. This reexamination hints that it may in fact be true - that is, participation in mediation may enhance parties\u27 perception of procedural justice. Before we can be confident in the answer to this question, however, research is needed that carefully compares the experiences of parties in mediation with those in unassisted negotiation
Institutionalization: What do empirical studies tell us about court mediation?
In the 25 years since the Pound Conference, federal and state courts throughout the country have adopted mediation programs to resolve civil disputes. This increased use of mediation has been accompanied by a small but growing body of research examining the effects of certain choices in designing and implementing court-connected mediation programs.
This article focuses on the lessons that seem to be emerging from the available empirical data regarding best practices for programs that mediate non-family civil matters. Throughout the article, we consider the answers provided by research to three questions: (1) How does program design affect the success of the institutionalization of mediation? (2) In what ways do design choices affect the likelihood of achieving settlement of cases? and (3) Which program design choices affect litigants\u27 perceptions of the procedural justice provided by court-connected mediation? Because these issues of institutionalization, settlement and justice are so important to the success and quality of court-connected mediation, they must be considered carefully in. deciding both how to structure new court-connected mediation programs and how to improve existing programs
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Innovative Selective Laser Sintering Rapid Manufacturing using Nanotechnology
The objective of this research is to develop an improved nylon 11 (polyamide 11) polymer
with enhanced flame retardancy, thermal, and mechanical properties for selective laser sintering
(SLS) rapid manufacturing (RM). A nanophase was introduced into nylon 11 via twin screw
extrusion to provide improved material properties of the polymer blends. Atofina (now known
as Arkema) RILSAN® nylon 11 injection molding polymer pellets was used with three types of
nanoparticles: chemically modified montmorillonite (MMT) organoclays, nanosilica, and carbon
nanofibers (CNF) to create nylon 11 nanocomposites. Wide angle X-ray diffraction (WAXD)
and transmission electron microscopy (TEM) were used to determine the degree of dispersion.
Fifteen nylon 11 nanocomposites and control nylon 11 were fabricated by injection molding.
Flammability properties (using a cone calorimeter with a radiant flux of 50 kW/m2
) and
mechanical properties such as tensile strength and modulus, flexural modulus, elongation at
break were determined for the nylon 11 nanocomposites and compared with the baseline nylon
11. Based on flammability and mechanical material performance, five polymers including four
nylon 11 nanocomposites and a control nylon 11 were cryogenically ground into fine powders
for SLS RM. SLS specimens were fabricated for flammability, mechanical, and thermal
properties characterization. Nylon 11-CNF nanocomposites exhibited the best overall properties
for this study.Mechanical Engineerin
Intravenöse Midazolam-Ketamin-Anästhesie zur geschlossenen Reposition der Vorderarmfraktur bei Kindern: Bringt eine zusätzliche axilläre Plexusblockade Vorteile?
Zusammenfassung: Hintergrund: Das Ziel dieser Studie war es zu vergleichen, ob der intravenöse Ketaminbedarf bei Midazolam-Ketamin-Anästhesie durch die Kombination mit einer axillären Plexusblockade zur geschlossenen Reposition einer Vorderarmfraktur bei Kindern reduziert werden kann. Methoden: Mit dem Einverständnis der Ethikkommission wurde eine retrospektive Gruppenanalyse bei Kindern durchgeführt, die in den Jahren 2000-2001 eine Midazolam-Ketamin-Anästhesie (GruppeA) oder in den Jahren 2002-2004 eine Midazolam-Ketamin-Anästhesie in Kombination mit einer axillären Plexusblockade (GruppeB) zur geschlossenen Reposition einer Vorderarmfraktur erhielten. Der Bedarf an Ketamin und postoperativen Analgetika wurde erfasst. Die Daten der Gruppen wurden mit dem Mann-Whitney-U-Test (nichtnormalverteilte Daten) oder dem T-Test (normalverteilte Daten) und dem χ2-Test verglichen (p<0,05). Ergebnisse: Insgesamt wurden 455Kinder (GruppeA: 225, GruppeB: 230) in die Studie aufgenommen. Der Bedarf an intravenösem Ketamin differierte statistisch nicht signifikant zwischen den beiden Gruppen (p=0,154). Der Ketaminbedarf in GruppeB wurde jedoch signifikant geringer, wenn das Zeitintervall zwischen dem Beginn der Plexusanästhesie und dem Beginn der Intervention mehr als 15min betrug (p<0,05). Patienten der GruppeB benötigten weniger Analgetika in der postoperativen Phase (p<0,01). Schlussfolgerung: Durch die Kombination der Midazolam-Ketamin-Anästhesie mit der axillären Plexusblockade zur geschlossenen Reposition einer Vorderarmfraktur bei Kindern ließ sich der Bedarf an Ketamin in der klinischen Routine einer Notfallstation nicht reduziere
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Intumescent Flame Retardant Polyamide 11 Nanocomposites
Current polyamide 11 and 12 are lacking in fire retardancy and high strength/high heat
resistance characteristics for a plethora of fabricated parts that are desired and required
for performance driven applications. The introduction of selected nanoparticles such as
surface modified montmorillonite (MMT) clay or carbon nanofibers (CNFs), combined
with a conventional intumescent flame retardant (FR) additive into the polyamide
11/polyamide 12 (PA11/PA12) by melt processing conditions has resulted in the
preparation of a family of intumescent polyamide nanocomposites. These intumescent
polyamide 11 and 12 nanocomposites exhibit enhanced polymer performance
characteristics, i.e., fire retardancy, high strength and high heat resistance and are
expected to expand the market opportunities for polyamide 11 and polyamide 12 polymer
manufacturers.
The objective of this research is to develop improved polyamide 11 and 12 polymers with
enhanced flame retardancy, thermal, and mechanical properties for selective laser
sintering (SLS) rapid manufacturing (RM). In the present study, a nanophase was
introduced into the polyamide 11 and combining it with a conventional intumescent FR
additive via twin screw extrusion. Arkema RILSAN® polyamide 11 molding polymer
pellets were examined with two types of nanoparticles: chemically modified
montmorillonite (MMT) organoclays, and carbon nanofibers (CNFs); and Clairant’s
Exolit® OP 1230 intumescent FR additive were used to create a family of FR
intumescent polyamide 11 nanocomposites.
Transmission electron microscopy (TEM) was used to determine the degree of
nanoparticles dispersion. Injection molded specimens were fabricated for physical,
thermal, and flammability measurements. Thermal stability of these intumescent
polyamide 11 nanocomposites was examined by TGA. Flammability properties were
obtained using the Cone Calorimeter at an external heat flux of 35 kW/m
2
and UL 94
Test Method. Heat deflection temperatures (HDT) were also measured. TEM
micrographs, physical, thermal, and flammability properties are presented. FR
intumescent polyamide 11 nanocomposites properties are compared with polyamide 11
baseline polymer. Based on flammability and mechanical material performance, selective
polymers including polyamide 11 nanocomposites and control polyamide 11 will be
cryogenically ground into fine powders for SLS RM processing. SLS specimens will be
fabricated for thermal, flammability, and mechanical properties characterization.Mechanical Engineerin
Thermoregulatory, metabolic, and cardiovascular responses during 88 min of full-body ice immersion - A case study.
Exposure to extreme cold environments is potentially life-threatening. However, the world record holder of full-body ice immersion has repeatedly demonstrated an extraordinary tolerance to extreme cold. We aimed to explore thermoregulatory, metabolic, and cardiovascular responses during 88 min of full-body ice immersion. We continuously measured gastrointestinal temperature (Tgi ), skin temperature (Tskin), blood pressure, and heart rate (HR). Oxygen consumption (VO2 ) was measured at rest, and after 45 and 88 min of ice immersion, in order to calculate the metabolic heat production. Tskin dropped significantly (28-34°C to 4-15°C) and VO2 doubled (5.7-11.3 ml kg-1 min-1 ), whereas Tgi (37.6°C), HR (72 bpm), and mean arterial pressure (106 mmHg) remained stable during the first 30 min of cold exposure. During the remaining of the trial, Tskin and VO2 remained stable, while Tgi gradually declined to 37.0°C and HR and mean arterial blood pressure increased to maximum values of 101 bpm and 115 mmHg, respectively. Metabolic heat production in rest was 169 W and increased to 321 W and 314 W after 45 and 80 min of ice immersion. Eighty-eight minutes of full-body ice immersion resulted in minor changes of Tgi and cardiovascular responses, while Tskin and VO2 changed markedly. These findings may suggest that our participant can optimize his thermoregulatory, metabolic, and cardiovascular responses to challenge extreme cold exposure
The cohesin ring uses its hinge to organize DNA using non-topological as well as topological mechanisms
As predicted by the notion that sister chromatid cohesion is mediated by entrapment of sister DNAs inside cohesin rings, there is perfect correlation between co-entrapment of circular minichromosomes and sister chromatid cohesion. In most cells where cohesin loads without conferring cohesion, it does so by entrapment of individual DNAs. However, cohesin with a hinge domain whose positively charged lumen is neutralized loads and moves along chromatin despite failing to entrap DNAs. Thus, cohesin engages chromatin in non-topological, as well as topological, manners. Since hinge mutations, but not Smc-kleisin fusions, abolish entrapment, DNAs may enter cohesin rings through hinge opening. Mutation of three highly conserved lysine residues inside the Smc1 moiety of Smc1/3 hinges abolishes all loading without affecting cohesin’s recruitment to CEN loading sites or its ability to hydrolyze ATP. We suggest that loading and translocation are mediated by conformational changes in cohesin’s hinge driven by cycles of ATP hydrolysis
Microfluidic systems for the analysis of the viscoelastic fluid flow phenomena in porous media
In this study, two microfluidic devices are proposed as simplified 1-D microfluidic analogues of a porous medium. The objectives are twofold: firstly to assess the usefulness of the microchannels to mimic the porous medium in a controlled and simplified manner, and secondly to obtain a better insight about the flow characteristics of viscoelastic fluids flowing through a packed bed. For these purposes, flow visualizations and pressure drop measurements are conducted with Newtonian and viscoelastic fluids. The 1-D microfluidic analogues of porous medium consisted of microchannels with a sequence of contractions/ expansions disposed in symmetric and asymmetric arrangements. The real porous medium is in reality, a complex combination of the two arrangements of particles simulated with the microchannels, which can be considered as limiting ideal configurations. The results show that both configurations are able to mimic well the pressure drop variation with flow rate for Newtonian fluids. However, due to the intrinsic differences in the deformation rate profiles associated with each microgeometry, the symmetric configuration is more suitable for studying the flow of viscoelastic fluids at low De values, while the asymmetric configuration provides better results at high De values. In this way, both microgeometries seem to be complementary and could be interesting tools to obtain a better insight about the flow of viscoelastic fluids through a porous medium. Such model systems could be very interesting to use in polymer-flood processes for enhanced oil recovery, for instance, as a tool for selecting the most suitable viscoelastic fluid to be used in a specific formation. The selection of the fluid properties of a detergent for cleaning oil contaminated soil, sand, and in general, any porous material, is another possible application
Dr. Zompo: an online data repository for Zostera marina and Posidonia oceanica ESTs
As ecosystem engineers, seagrasses are angiosperms of paramount ecological importance in shallow shoreline habitats around the globe. Furthermore, the ancestors of independent seagrass lineages have secondarily returned into the sea in separate, independent evolutionary events. Thus, understanding the molecular adaptation of this clade not only makes significant contributions to the field of ecology, but also to principles of parallel evolution as well. With the use of Dr. Zompo, the first interactive seagrass sequence database presented here, new insights into the molecular adaptation of marine environments can be inferred. The database is based on a total of 14 597 ESTs obtained from two seagrass species, Zostera marina and Posidonia oceanica, which have been processed, assembled and comprehensively annotated. Dr. Zompo provides experimentalists with a broad foundation to build experiments and consider challenges associated with the investigation of this class of non-domesticated monocotyledon systems. Our database, based on the Ruby on Rails framework, is rich in features including the retrieval of experimentally determined heat-responsive transcripts, mining for molecular markers (SSRs and SNPs), and weighted key word searches that allow access to annotation gathered on several levels including Pfam domains, GeneOntology and KEGG pathways. Well established plant genome sites such as The Arabidopsis Information Resource (TAIR) and the Rice Genome Annotation Project are interfaced by Dr. Zompo. With this project, we have initialized a valuable resource for plant biologists in general and the seagrass community in particular. The database is expected to grow together with more data to come in the near future, particularly with the recent initiation of the Zostera genome sequencing project
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