The absorption of UE funds in the current context of the cohesion policy

Romania continues to be affected by the global recession. It has suffered a significant reduction in foreign investment since the start of the recession, as investors have moved away from emerging markets in search for security. Developing an appropriate, focused strategy for the allocation of EU funds is only the first, though perhaps the most important step in implementing the EU cohesion policy. The successful implementation of EU co-funded projects is contingent not only upon the effectiveness of these countries’ administrative systems, but also on the activity of the potential beneficiaries

The link Between Stock Exchange Sectors and Indices: Implications During the COVID-19 Pandemic

The paper investigates the impact of the COVID-19 pandemic, using the event study approach for the Bucharest Stock Exchange, by which Bucharest Stock Indices and listed firms grouped by sectors were analyzed. The paper uses three important event days, 20 January 2020, 11 March 2020, and 15 March 2020. The findings demonstrate that initially investors were not concerned about the pandemic, showing that they did not realize the extent of globalization and transmission of events on financial markets. Both after 11 March and after 15 March 2020, stock indices have declined, investors becoming worried about the prospects of their dividends and the stock liquidity. The most affected sectors were those related to metallurgical industry, IT&C. After the lockdown, there was a reversal for some sectors like pharmaceutical and biotechnology, electricity production, transportation and distribution, and IT&C. Understanding the intensity and direction of the link between some sectors and indices may influence investment strategies and help in hedging, especially in times of pandemics

Dielectric selective mirror for intracavity wavelength selection in far-infrared p-Ge lasers

A robust metal-free intracavity fixed-wavelength selector for the cryogenically cooled far-infrared p-Ge laser is demonstrated. The device is a back mirror consisting of a thin silicon etalon and dielectric SrTiO3 flat. A laser line width of 0.2 cm-1 is achieved, which corresponds to an active cavity finesse of similar to0.15. The wavelength position and spectral purity are maintained over a wide range of laser operating fields. Use of SrTiO3 lowers the laser resonance line frequencies by similar to1 cm-1 compared with expectations for metal mirrors. The effect is due to phase shift, which is determined from far-infrared reflectivity measurements of SrTiO3. A p-Ge laser with such selector is free from danger of electrical breakdown and mirror oxidation during repeatable thermal cycling, which makes it more reliable than previous selection schemes for practical applications

Estudio Socioeconómico Del Municipio De Pueblo viejo

El Municipio de Pueblo viejo se encuentra localizado en el sector Noroccidental del Departamento del Magdalena, dentro de la región fisiográfica del Delta Exterior del Río Magdalena, a 11°00' de latitud Norte y a 74°17' de longitud Oeste de Greenwich, con una extensión total de 49.700 Ha. Goza de inmejorables condiciones de ubicación para alcanzar un Óptimo desarrollo en todas las actividades que en él se realizan cuáles son fundamentalmente: la pesca, la ganadería y la agricultura, pero a pesar de esto, es decir, del Mar Caribe, la Ciénaga Grande de Santa Marta, los fértiles suelos, disposición de la mejor riqueza hídrica del Departamento, buen clima, regular precipitación y gran extensión, su desarrollo en el campo se encuentra entrabado. Muchas riquezas naturales se han destruido. La Ciénaga Grande de Santa Marta se encuentra en perfecto progresivo de contaminación debido al uso irracional de los pesticidas agrícolas, característica del individualismo capitalista. El sector pesquero a pesar de la extensión del mar y de la Ciénaga Grande de Santa Marta y de su riqueza marina, coma los sectores anteriores, se encuentra sometido también al marco del atraso. Todos los métodos e instrumentos de pesca son rudimentarios, la explotación tecnificada y el procesamiento de los productos se lleva a cabo para empresas de capital mixto, los habitantes del municipio a pesar de las riquezas de es te, no disponen de los mínimos servicios que le garanticen adecuadas condiciones para su salud. En cuanto a educación se refiere, a pesar de las características del municipio de que la mayoría de sus habitantes son jóvenes, son pocas las escuelas y colegios que existen y los que están se encuentran en muy malas condiciones. En resumen, el municipio es rico por naturaleza, pero se encuentra empobrecido por el poder de la burguesía, terratenientes y la dominación extranjera que padece nuestro país

Application of the Nanofiltration Process for Concentration of Polyphenolic Compounds from Geranium robertianum and Salvia officinalis Extracts

The aim of this study was to prove the efficiency of the nanofiltration process for the concentration of polyphenolic compounds from Geranium robertianum and Salvia officinalis extracts and to evaluate the extract’s antioxidant activity. A lab-scale cross-flow set-up using flat-sheet configuration membrane was employed for all experiments. Two nanofiltration membranes have been used: SelRO MPF-36 (Koch membrane) and an organic-inorganic membrane (polysulfone with SBA-15-NH2). When the organic-inorganic membranes were used in the nanofiltration process, the obtained concentrated extracts proved to have higher polyphenol and flavonoid rejections, in both cases (Geranium robertianum and Salvia officinalis). The obtained values were over 88 % DPPH inhibition, for concentrated extracts, using the DPPH method. The concentrated extracts obtained after nanofiltration NF2 (organic-inorganic membrane) had the strongest scavenging activity for all extracts and almost completely inhibited DPPH absorption (92.9 % for Geranium robertianum concentrated extract and 90.1 % for Salvia officinalis concentrated extract). These features turn the studied, concentrated extracts into a good source for further medicinal applications

Interaction of classical swine fever virus with dendritic cells

Functional disruption of dendritic cells (DCs) is an important strategy for viral pathogens to evade host defences. Monocytotropic viruses such as classical swine fever virus (CSFV) could employ such a mechanism, since the virus can suppress immune responses and induce apoptosis without infecting lymphocytes. Here, CSFV was shown to infect and efficiently replicate in monocyte- and in bone marrow-derived DCs. Interestingly, the infected DCs displayed neither modulated MHC nor CD80/86 expression. Stimulation of DCs with IFN-/TNF- or polyinosinic¿polycytidylic acid (pIC) induced phenotypic maturation with increased MHC and CD80/86 expression, both with mock-treated and infected DCs. In addition, the T cell stimulatory capacity of CSFV-infected DCs was maintained both in a polyclonal T cell stimulation and in specific antigen-presentation assays, requiring antigen uptake and processing. Interestingly, similar to macrophages, CSFV did not induce IFN- responses in these DCs and even suppressed pIC-induced IFN- induction. Other cytokines including interleukin (IL)-6, IL-10, IL-12 and TNF- were not modulated. Taken together, these results demonstrated that CSFV can replicate in DCs and control IFN type I responses, without interfering with the immune reactivity. These results are interesting considering that DC infection with RNA viruses usually results in DC activation

Task shifting: the answer to the human resources crisis in Africa?

Ever since the 2006 World Health Report advocated increased community participation and the systematic delegation of tasks to less-specialized cadres, there has been a great deal of debate about the expediency, efficacy and modalities of task shifting

The Mast Cell Degranulator Compound 48/80 Directly Activates Neurons

Background Compound 48/80 is widely used in animal and tissue models as a “selective” mast cell activator. With this study we demonstrate that compound 48/80 also directly activates enteric neurons and visceral afferents. Methodology/Principal Findings We used in vivo recordings from extrinsic intestinal afferents together with Ca++ imaging from primary cultures of DRG and nodose neurons. Enteric neuronal activation was examined by Ca++ and voltage sensitive dye imaging in isolated gut preparations and primary cultures of enteric neurons. Intraluminal application of compound 48/80 evoked marked afferent firing which desensitized on subsequent administration. In egg albumen-sensitized animals, intraluminal antigen evoked a similar pattern of afferent activation which also desensitized on subsequent exposure to antigen. In cross-desensitization experiments prior administration of compound 48/80 failed to influence the mast cell mediated response. Application of 1 and 10 µg/ml compound 48/80 evoked spike discharge and Ca++ transients in enteric neurons. The same nerve activating effect was observed in primary cultures of DRG and nodose ganglion cells. Enteric neuron cultures were devoid of mast cells confirmed by negative staining for c-kit or toluidine blue. In addition, in cultured enteric neurons the excitatory action of compound 48/80 was preserved in the presence of histamine H1 and H2 antagonists. The mast cell stabilizer cromolyn attenuated compound 48/80 and nicotine evoked Ca++ transients in mast cell-free enteric neuron cultures. Conclusions/Significance The results showed direct excitatory action of compound 48/80 on enteric neurons and visceral afferents. Therefore, functional changes measured in tissue or animal models may involve a mast cell independent effect of compound 48/80 and cromolyn