Brecha digital y uso de las TIC en estudiantes universitarios

Tanto el acceso a las Tecnologías de la Información y la Comunicación (TIC) como la capacitación para usarlas y el buen uso de las mismas son elementos que intervienen de un modo u otro en toda la etapa universitaria de un estudiante. En esta comunicación se muestra, de modo preliminar, los resultados sobre el acceso a las TIC y los usos que hacen los estudiantes universitarios de los servicios Web 2.0, así como su presencia en las redes sociales. La población objeto de este estudio de caso son los estudiantes matriculados en primer curso del grado de Trabajo Social de la Universidad de Alicante en el curso 2013-2014. La metodología utilizada en esta investigación es cuantitativa mediante la aplicación de la técnica de la encuesta electrónica autoaplicada a través de Internet

Trabajo social en España. De los recortes sociales a la arena pública

Los derechos humanos están sufriendo severos recortes con la excusa de que las políticas internacionales exigen ajustes económicos. Hay un cambio drástico de política. Las universidades y trabajadores sociales profesionales junto con las organizaciones civiles, están participando en el debate público y denunciando la calidad de estas políticas o su inexistencia cuando no las hay.La investigación que lleva a estos resultados ha recibido financiación por el People programme (Marie Curie Actions) del European Union's seventh framework programme Fp7/2007-2013 bajo el acuerdo Rea de subvención n.318938

Advocacy and policy influencing for social change: Responsibility of social workers and implications for training

La incidencia en las políticas sociales es una importante función profesional de las trabajadoras sociales que precisa ser integrada en la educación teórica y práctica en Trabajo Social. Este artículo indaga sobre los fundamentos de esta función de incidencia en los cambios sociales promoviendo políticas sociales que reconozcan los derechos humanos. Partiendo de los referentes internacionales del trabajo social, se analiza el caso de España teniendo en cuenta los códigos deontológicos, los planes de estudio en Trabajo Social, la práctica profesional y los nuevos Grados en Trabajo Social. Se concluye planteando interrogantes sobre el grado de responsabilidad y de implicación de las universidades y Colegios profesionales en coherencia con los principios y valores del Trabajo Social.Advocacy and social policy influencing is an important professional role of social workers that needs to be integrated into education and training on social work. This article explores the fundamentals of this advocacy role in social change through social policies that recognize human rights. Based on the international benchmarks of social work, the case of Spain is analyzed considering ethical codes, the curricula in social work, professional practice and the new Degree in Social Work. The article raises some questions about the degree of responsibility and involvement that universities and professional associations have, in coherence with the principles and values of social work.Este trabajo está financiado en parte, por el proyecto FP7 PEOPLE-2012-IRSES. Grant Agreement Number 318938. Civil Engagement in Social Work: Developing Global Models (CIVIL-SW). PIRSES-GA-2012-318938

Social Services in Times of Economic and Social Crisis: The case of Spain

The financial and economic crisis which originated in 2008 has had a severe impact on the population of the Southern European countries. The economic policies of austerity and public deficit control, as well as the neo-liberal and conservative social policies are redefining the public social protection systems, in particular the Social Services. In order to get to understand the current situation, we shall explain how the Social Services were developed in Spain and analyse the causes and consequences of the economic crisis. The working hypothesis is that the greater the increase on the population’s needs, the more developed the Social Services should be. We carried out a descriptive analysis of the situation as far as the social impacts of the crisis per region are concerned. We tested the hypothesis through a parametric model of analysis of variance (one-way ANOVA) triangulating with the non-parametric Kruscal-Wallis test. The working hypothesis failed. The regions with better developed Social Services show a lower level of poverty and social exclusion. The challenges that the public Social Services system faces in times of crisis is three-fold: 1) re-modelling of local administration and transferring of the municipal Social Services responsibilities to the regional administration; 2) an increase of the population at risk of poverty and social exclusion 3) impact on social policies.The research leading to these results has received funding from the European Union Seventh Framework Programme FP7-PEOPLE-2012-IRSES under grant agreement No 318938

SARS-CoV-2 immunochromatographic IgM/IgG rapid test in pregnancy: A false friend?

Background: An increasing body of evidence has revealed that SARS-CoV-2 infection in pregnant women could increase the risk of adverse maternal and fetal outcomes. Careful monitoring of pregnancies with COVID-19 and measures to prevent neonatal infection are warranted. Therefore, rapid antibody tests have been suggested as an efficient screening tool during pregnancy. Cases: We analysed the clinical performance during pregnancy of a rapid, lateral-flow immunochromatographic assay for qualitative detection of SARS-CoV-2 IgG/IgM antibodies. We performed a universal screening including 169 patients during their last trimester of pregnancy. We present a series of 14 patients with positive SARS-CoV-2 immunochromatographic assay rapid test result. Immunochromatographic assay results were always confirmed by chemiluminescent microparticle immunoassays for quantitative detection of SARS-CoV-2 IgG and IgM+IgA antibodies as the gold standard. We observed a positive predictive value of 50% and a false positive rate of 50% in pregnant women, involving a significantly lower diagnostic performance than reported in non-pregnant patients. Discussion: Our data suggest that although immunochromatographic assay rapid tests may be a fast and profitable screening tool for SARS-CoV-2 infection, they may have a high false positive rate and low positive predictive value in pregnant women. Therefore, immunochromatographic assay for qualitative detection of SARS-CoV-2 IgG/IgM antibodies must be verified by other test in pregnant patients

Insights into the mechanism of cell death induced by saporin delivered into cancer cells by an antibody fusion protein targeting the transferrin receptor 1

We previously developed an antibody-avidin fusion protein (ch128.1Av) that targets the human transferrin receptor 1 (TfR1) and exhibits direct cytotoxicity against malignant B cells in an iron-dependent manner. ch128.1Av is also a delivery system and its conjugation with biotinylated saporin (b-SO6), a plant ribosome-inactivating toxin, results in a dramatic iron-independent cytotoxicity, both in malignant cells that are sensitive or resistant to ch128.1Av alone, in which the toxin effectively inhibits protein synthesis and triggers caspase activation. We have now found that the ch128.1Av/b-SO6 complex induces a transcriptional response consistent with oxidative stress and DNA damage, a response that is not observed with ch128.1Av alone. Furthermore, we show that the antioxidant N-acetylcysteine partially blocks saporin-induced apoptosis suggesting that oxidative stress contributes to DNA damage and ultimately saporin-induced cell death. Interestingly, the toxin was detected in nuclear extracts by immunoblotting, suggesting the possibility that saporin might induce direct DNA damage. However, confocal microscopy did not show a clear and consistent pattern of intranuclear localization. Finally, using the long-term culture-initiating cell assay we found that ch128.1Av/b-SO6 is not toxic to normal human hematopoietic stem cells suggesting that this critical cell population would be preserved in therapeutic interventions using this immunotoxin.Fil: Daniels Wells, Tracy R.. University of California; Estados Unidos de América;Fil: Helguera, Gustavo Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. University of California; Estados Unidos de América;Fil: Rodríguez, José A.. University of California; Estados Unidos de América;Fil: Leoh, Lai Sum. University of California; Estados Unidos de América;Fil: Erb, Michael A.. University of California; Estados Unidos de América;Fil: Diamante, Graciel. University of California; Estados Unidos de América;Fil: Casero, David. University Of California; Estados Unidos de América;Fil: Pellegrini, Mateo. University of California; Estados Unidos de América;Fil: Martinez Maza, Otoniel. University of California; Estados Unidos de América;Fil: Penichet, Manuel L.. University of California; Estados Unidos de América

The luminosities of backsplash galaxies in constrained simulations of the Local Group

We study the differences and similarities in the luminosities of bound, infalling and the so-called backsplash (Gill et al. 2005) galaxies of the Milky Way and M31 using a hydrodynamical simulation performed within the Constrained Local UniversE Simulation (CLUES) project. The simulation models the formation of the Local Group within a self-consistent cosmological framework. We find that even though backsplash galaxies passed through the virial radius of their host halo and hence may have lost a (significant) fraction of their mass, their stellar populations are hardly affected. This leaves us with comparable luminosity functions for infalling and backsplash galaxies and hence little hope to decipher their past (and different) formation and evolutionary histories by luminosity measurements alone. Nevertheless, due to the tidal stripping of dark matter we find that the mass-to-light ratios have changed when comparing the various populations against each other: they are highest for the infalling galaxies and lowest for the bound satellites with the backsplash galaxies in-between.Comment: 9 pages, 10 figures, 1 table, accepted for publication in MNRA