497 research outputs found
The SFXC software correlator for Very Long Baseline Interferometry: Algorithms and Implementation
In this paper a description is given of the SFXC software correlator,
developed and maintained at the Joint Institute for VLBI in Europe (JIVE). The
software is designed to run on generic Linux-based computing clusters. The
correlation algorithm is explained in detail, as are some of the novel modes
that software correlation has enabled, such as wide-field VLBI imaging through
the use of multiple phase centres and pulsar gating and binning. This is
followed by an overview of the software architecture. Finally, the performance
of the correlator as a function of number of CPU cores, telescopes and spectral
channels is shown.Comment: Accepted by Experimental Astronom
Application of in vivo Laser Scanning Microscopy to Visualise the Penetration of a Fluorescent Dye in Solution and in Liposomes into the Skin after Pre-Treatment with Microneedles
Magnetoresistance of a 2-dimensional electron gas in a random magnetic field
We report magnetoresistance measurements on a two-dimensional electron gas
(2DEG) made from a high mobility GaAs/AlGaAs heterostructure, where the
externally applied magnetic field was expelled from regions of the
semiconductor by means of superconducting lead grains randomly distributed on
the surface of the sample. A theoretical explanation in excellent agreement
with the experiment is given within the framework of the semiclassical
Boltzmann equation.Comment: REVTEX 3.0, 11 pages, 3 Postscript figures appended. The manuscript
can also be obtained from our World Wide Web server:
http://roemer.fys.ku.dk/randmag.ht
Connective tissue degeneration: Mechanisms of palmar fascia degeneration (Dupuytren’s disease)
Dupuytren’s disease is a connective tissue disorder of the hand causing excessive palmar fascial fibrosis with associated finger contracture and disability. The aetiology of the disease is heterogeneous, with both genetic and environmental components. The connective tissue is abnormally infiltrated by myofibroblasts that deposit collagen and other extracellular matrix proteins. We describe the clinical profile of Dupuytren’s disease along with current therapeutic schemes. Recent findings on molecular and cellular parameters that are dysregulated in Dupuytren’s disease, which may contribute to the onset of the disease, and the role of resident inflammation promoting fibrosis, are highlighted. We review recent literature focusing on non-myofibroblast cell types (stem cell-like cells), their pro-inflammatory and pro-fibrotic role that may account for abnormal wound healing response
Development of a Neural Network Embedding for Quantifying Crack Pattern Similarity in Masonry Structures
The degree of similarity between damage patterns often correlates with the likelihood
of having similar damage causes. Therefore, deciding whether crack patterns are similar is one of
the key steps in assessing the conditions of masonry structures. To our knowledge, no literature has
been published regarding masonry crack pattern similarity measures that would correlate well
with assessment by structural engineers. Hence, currently, similarity assessments are solely
performed by experts and require considerable time and effort. Moreover, it is expensive, limited by
the availability of experts, and yields only qualitative answers. In this work, we propose an
automated approach that has the potential to overcome the above shortcomings and perform
comparably with experts. At its core is a deep neural network embedding that can be used to calculate a numerical distance between crack patterns on comparable façades. The embedding is
obtained from fitting a deep neural network to perform a classification task; i.e., to predict the crack
pattern archetype label from a crack pattern image. The network is fitted to synthetic crack patterns
simulated using a statistics-based approach proposed in this work. The simulation process can account for important crack pattern characteristics such as crack location, orientation, and length. The embedding transforms a crack pattern (raster image) into a 64-dimensional real-valued vector space where the closeness between two vectors is calculated as the cosine of their angle. The proposed approach is tested on 2D façades with and without openings, and with synthetic crack patterns that consist of a single crack and multiple cracks
Measurement of the half-life of the T= mirror decay of Ne and its implication on physics beyond the standard model
The superallowed mixed mirror decay
of Ne to F is excellently suited for high precision studies of
the weak interaction. However, there is some disagreement on the value of the
half-life. In a new measurement we have determined this quantity to be
= s, which differs
from the previous world average by 3 standard deviations. The impact of this
measurement on limits for physics beyond the standard model such as the
presence of tensor currents is discussed.Comment: 5 pages, 3 figures, 1 tabl
Inguinal microbiome in patients undergoing an endovascular aneurysm repair:Application of next-generation sequencing of the 16S-23S rRNA regions
Background: Surgical site infection (SSI) remains a hazardous complication after vascular surgery. In this pilot study we investigated the inguinal microbiome in skin biopsies using histology and 16S-23S rDNA Next Generation Sequencing (NGS). Our hypothesis was that causative microorganisms of SSI are present in the inguinal microbiome. Methods: Data on surgical site infections and skin samples from the Percutaneous in Endovascular Repair versus Open (PiERO) trail were evaluated. Two patients with SSI were matched for age and comorbidity to eight matching patients of the PiERO trial. All patients were treated for an abdominal aortic aneurysm with endovascular repair. Nasal and perineal cultures were taken preoperatively to detect Staphylococcus aureus carriage. After disinfection with chlorhexidine, groin biopsies were taken to identify bacteria in deeper skin layers. All samples were subjected to histological analysis and culture-free 16S-23S rDNA NGS. Results: Staphylococcus aureus species were cultured in 5 out of 20 preoperative nasal and perineal swaps. Histology detected only a few bacteria, NGS of the 16S-23S rRNA regions identified DNA of bacterial species in all biopsies (20/20). Most identified genera and species proved to be known skin flora bacteria. No relation was found between SSIs and the preoperative microbiome. Conclusion: In this pilot study, an innovative analysis of the preoperative microbiome using 16S-23S rDNA NGS did not show a relation with the occurrence of a surgical site infection. No pathogenic bacterial species were present in the inguinal skin after disinfection with chiorhexidine
Development of a thermal ionizer as ion catcher
An effective ion catcher is an important part of a radioactive beam facility
that is based on in-flight production. The catcher stops fast radioactive
products and emits them as singly charged slow ions. Current ion catchers are
based on stopping in He and H gas. However, with increasing intensity of
the secondary beam the amount of ion-electron pairs created eventually prevents
the electromagnetic extraction of the radioactive ions from the gas cell. In
contrast, such limitations are not present in thermal ionizers used with the
ISOL production technique. Therefore, at least for alkaline and alkaline earth
elements, a thermal ionizer should then be preferred. An important use of the
TRIP facility will be for precision measurements using atom traps. Atom
trapping is particularly possible for alkaline and alkaline earth isotopes. The
facility can produce up to 10 s of various Na isotopes with the
in-flight method. Therefore, we have built and tested a thermal ionizer. An
overview of the operation, design, construction, and commissioning of the
thermal ionizer for TRIP will be presented along with first results for
Na and Na.Comment: 10 pages, 4 figures, XVth International Conference on Electromagnetic
Isotope Separators and Techniques Related to their Applications (EMIS 2007
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