Features of the distribution of the concentration on the mucous stomach of active and inactive forms of helicobacterial infection in patients with chronic non-atrophic gastritis, suffering and not suffering from chronic constipation

The frequency of detection and the degree of colonization of the gastric mucosa by the active and inactive form of Helicobacter pylori infection was analyzed in 50 patients with chronic non-atrophic gastritis, suffering from chronic constipation, and in 50 patients with chronic non-atrophic gastritis, who did not suffer from constipation. In the group of patients suffering from chronic constipation, the frequency of occurrence of the active form of Helicobacter pylori infection in different topographic zones of the stomach ranged from 46% to 56% with an average degree of mucosal seeding from 1.12 ± 0.13 (+) to 1.48 ± 0.13 (+), the frequency of occurrence of an inactive form of Helicobacter pylori infection in different topographic zones of the stomach ranged from 0% to 48% with an average degree of mucosal colonization from 0 ± 0.0 (+) to 1.30 ± 0.13 (+), while while in the group of patients who did not suffer from chronic constipation, the frequency of occurrence of an act distinct Helicobacter pylori infection in different topographic zones of the stomach ranged from 36% to 52% with an average degree of mucosal seeding from 1.02 ± 0.13 (+) to 1.34 ± 0.13 (+), and the frequency of occurrence of the inactive Helicobacter pylori infections in different topographic zones of the stomach ranged from 0% to 58% with an average degree of mucosal seeding from 0 ± 0.0 (+) to 1.56 ± 0.13 (+). In patients of the first group, the frequency of detection of intracellular "depots" of HP infection was 2.3 times higher than in patients of the second group

Features of laboratory indicators of severe community-acquired pneumonia.

Based on data from the prospective analysis of patients with severe community-acquired pneumonia over the year of observation, the article presents data on the features of laboratory indicators of the course of severe community-acquired pneumonia. Patients included in the study were hospitalized in the pulmonology department (or therapy), and in the intensive care unit of three clinical hospitals in the city of Dnipro, namely, the Dnipropetrovsk City Clinical Hospital N 6, the Dnipropetrovsk City Clinical Hospital N 2, the Dnipropetrovsk City Clinical Hospital N 16, which are the clinical bases of the SE “Dnipropetrovsk medical academy of Health Ministry of Ukraine”. In the course of studies, the dependence of the severity of patients' state on the severity of inflammatory markers and fibrosis markers was shown. The effect of the prognostic significance of the level of the enzyme TGFβ and C-reactive protein (CRP) for the evaluation of possibility of formation of long-term pathological changes after a severe community-acquired pneumonia has been examined. It was established that a high level of CRP (38.3 [11.3, 150.9] mg / L) and TGFβ (20149.1±424.0 pg/ml) in the blood plasma of patients can be considered as an additional marker of the severity of the course of community-acquired pneumonia. The results can be the basis for a more individual approach to the development of diagnostic and therapeutic programs for patients with severe community-acquired pneumoni

Regional Investment Policy Under the Impact of Budget Limitations and Economic Sanctions

The article is devoted to the assessment of influence of budgetary restrictions and economic sanctions on investment policy of a region. The paper studies the bilateral negative effect on socio-economic development of regions from both the external sanctions and braking mechanism of economic development within the country. On the basis of the comparative and statistical analysis, the need to change focus of investment policy from the growth in volumes to qualitative perfecting is proved. The new direction of investment policy connected with the import substitution process realization, its combination with acceleration of innovative development on the certain example of Sverdlovsk region is analyzed. The conclusions and offers stated in the article are applicable to the public authorities of subjects of the Russian Federation, experts in the sphere of regional investment policy and improvement of investment climate, and also the specialized organizations specialized in attracting investment and work with investors in regions of Russia

Production of spectator hypermatter in relativistic heavy-ion collisions

We study the formation of large hyper-fragments in relativistic heavy-ion collisions within two transport models, DCM and UrQMD. Our goal is to explore a new mechanism for the formation of strange nuclear systems via capture of hyperons by relatively cold spectator matter produced in semi-peripheral collisions. We investigate basic characteristics of the produced hyper-spectators and evaluate the production probabilities of multi-strange systems. Advantages of the proposed mechanisms over an alternative coalescence mechanism are analysed. We also discuss how such systems can be detected taking into account the background of free hyperons. This investigation is important for the development of new experimental methods for producing hyper-nuclei in peripheral relativistic nucleus-nucleus collisions, which are now underway at GSI and are planned for the future FAIR and NICA facilities.Comment: 28 pages, including 10 figures. Submitted to Phys. Rev.

Characteristics of the electric field accompanying a longitudinal acoustic wave in a metal. Anomaly in the superconducting phase

The temperature dependence of the amplitude and phase of the electric potential arising at a plane boundary of a conductor when a longitudinal acoustic wave is incident normally on it is investigated theoretically and experimentally. The surface potential is formed by two contributions, one of which is spatially periodic inside the sample, with the period of the acoustic field; the second is aperiodic and arises as a result of an additional nonuniformity of the electron distribution in a surface layer of the metal. In the nonlocal region the second contribution is dominant. The phases of these contributions are shifted by approximately \pi /2. For metals in the normal state the experiment is in qualitative agreement with the theory. The superconducting transition is accompanied by catastrophically rapid vanishing of the electric potential, in sharp contrast to the theoretical estimates, which predict behavior similar to the BCS dependence of the attenuation coefficient for a longitudinal sound.Comment: 9 pages, 6 figure

Magnus force and acoustic Stewart-Tolman effect in type II superconductors

At zero magnetic field we have observed an electromagnetic radiation from superconductors subjected by a transverse elastic wave. This radiation has an inertial origin, and is a manifestation of the acoustic Stewart-Tolman effect. The effect is used for implementing a method of measurement of an effective Magnus force in type II superconductors. The method does not require the flux flow regime and allows to investigate this force for almost the whole range of the existence of the mixed state. We have studied behavior of the gyroscopic force in nonmagnetic borocarbides and Nb. It is found that in borocarbides the sign of the gyroscopic force in the mixed state is the same as in the normal state, and its value (counted for one vortex of unit length) has only a weak dependence on the magnetic field. In Nb the change of sign of the gyroscopic force under the transition from the normal to the mixed state is observed.Comment: 4 pages, 5 figure

Functional nitric oxide conjugate systems state/restored heart thiols of rats in modeling isadrine-pituitrin’s myocardial infarction using metabolite-tropic cardioprotector “Angiolin”

Background: According to modern researches, endothelial dysfunction (ED) is one of the primary pathogenetic elements of cardiovascular diseases (myocardial infarction [MI], ischemic heart diseases, cerebral ischemic stroke, atherosclerosis, arterial hypertension, pulmonary hypertension, heart failure, and dilated cardiomyopathy) as well as obesity, hyperlipidemia, diabetes and hyperhomocysteinemia. The aim of this work was to study the influence of potential metabolitotropic cardioprotector “Angiolin” on the parameters of conjugate systems nitric oxide (NO)/restored thiols in heart under isadrine-pituitrin MI.Methods: This study was performed on Wistar white rats weighing 190-210 g. Biochemical, immune-enzyme analysis and histoimmunechemical study were performed.Results: In histological sections of hearts of the rats receiving Angiolin in parenteral dosing 50 mg/kg 30 mins before each pituitrin injection the density of endothelial NO-synthase (NOS)-positive cells increased by 29% and the density of inducible NOS-positive cells decreased by 23.3%. In cytosolic fraction of myocardium homogenate NOS activity increased by 27%, the concentration of NO stable metabolites increased by 70% and the content of nitrosative stress marker nitrotyrosine decreased by 42% when compared with control group. At the same time in similar samples of heart homogenate the increase of restored thiol groups’ level by 53.3%, methionine - by 35.1%, cysteine - by 170% and activity of glutathione reductase - by 186% was noted. The administration of reference drug mildronate to the animals with MI in dose 100 mg/kg did not result in significant changes of the studied parameters of thiol-disulfide system and NO system of the heart when compared with control group.Conclusions: Angiolin does not influence directly on NOS in MI, but at the same time protects NO from nitrosative stress increasing restored equivalents of thiol-disulfide system

Проблеми обліку валютних різниць

Авраменко О. І., Беззуб А. В. Проблеми обліку валютних різниць / О.І. Авраменко, А.В. Беззуб // Авіація, промисловість, суспільство : матеріали І Міжнар. наук.-практ. конф., присвяч. 60-річчю КЛК ХНУВС (м. Кременчук, 14 трав. 2020 р.) : у 2 ч. – Харків : ХНУВС, 2020. – Ч. 2. – С. 23 - 25.Розглянуті питання відображення наслідків коливання валютних курсів та удосконалення відображення валютних різниць в обліку. Рассмотрены вопросы отражения последствий колебания валютных курсов и усовершенствование отражения валютных разниц в учете. The issues of reflection of the consequences of fluctuations are considered exchange rates and improving the reflection of currency differences in accounting

ДОСВІД ЗАПРОВАДЖЕННЯ МОДЕЛІ ПРОБЛЕМНО-ОРІЄНТОВАНОГО НАВЧАННЯ У ЗАПОРІЗЬКОМУ ДЕРЖАВНОМУ МЕДИЧНОМУ УНІВЕРСИТЕТІ

Problem-based learning appeared in the Ukrainian higher education fairly recently. Taking into account world’s best practices we can speak with certainty about its relevance and innovation. This work describes the experience of Zaporozhye State Medical University in PBL implementation into the junior medical students’ education in frames of Tempus project  530519-Tempus-1-2012-1-UK-TEMPUS-JPCR “Establishment of the Supra-Regional Network of the National Centers in Medical Education, focused on PBL and Virtual Patients” (“ePBLnet”). It also depicts some peculiarities in curriculum adaptation, OpenLabirynth platform use for case development based on virtual patients and role of Medical Education Centre of ZSMU.Проблемно-орієнтоване навчання в українській вищій медичній освіті з’явилося відносно недавно. Зважаючи на передовий світовий досвід, можна впевнено говорити про його актуальність та інноваційність. У даній роботі висвітлено досвід Запорізького державного медичного університету щодо впровадження проблемно-орієнтованого навчання у студентів молодших курсів медичного факультету у рамках проекту 530519-Tempus-1-2012-1-UK-TEMPUS-JPCR “Створення Міжрегіональної мережі національних центрів медичної освіти, головним напрямом яких є впровадження проблемно-орієнтованого навчання з використанням віртуальних пацієнтів” (“ePBLnet”). Описано особливості адаптації навчального плану, використання платформи OpenLabyrinth для створення кейсів на базі віртуальних пацієнтів, показано роль створеного Медичного освітнього центру при ЗДМУ