Do paranoid delusions exist on a continuum with subclinical paranoia? A multi-method taxometric study

Background There is widespread interest in whether psychosis exists on a continuum with healthy functioning. Previous research has implied that paranoia, a common symptom of psychosis, exists on a continuum but this has not been investigated using samples including both patients and non-patients and up-to-date taxometric methods. Aim To assess the latent structure of paranoia in a diverse sample using taxometric methods. Method We obtained data from 2836 participants, including the general population as well as at-risk mental state and psychotic patients using the P-scale of the Paranoia and Deservedness Scale. Data were analysed using three taxometric procedures, MAMBAC, MAXEIG and L-MODE (Ruscio, 2016), and two sets of paranoia indicators (subscales and selected items from the P scale), including and excluding the patient groups. Results Eleven of the twelve analyses supported a dimensional model. Using the full sample and subscales as indicators, the MAMBAC analysis was ambiguous. Overall, the findings converged on a dimensional latent structure. Conclusions A dimensional latent structure of paranoia implies that the processes involved in sub-clinical paranoia may be similar to those in clinical paranoia

Associations of vitamin D level and severity climacteric syndrome

The aim of the study - to determine the relationship between vitamin D levels and the severity of menopausal syndrome in postmenopausal women.Цель исследования - определить взаимосвязь уровня витамина D и степени тяжести климактерического синдрома у женщин в постменопауз

Results of observation of a family case of thyrotropic hormone resistance syndrome

The purpose of the study was to evaluate the development of children with congenital subclinical hypothyroidism and not receiving hormone replacement therapy in order to select therapeutic tactics.Цель исследования – оценить развитие детей, имеющих врожденный субклинический гипотиреоз и не получающих заместительную гормональную терапию, для выбора терапевтической тактики

The attitude of USMU students to vaccination against COVID-19

The aim of the study – to determine the attitude of medical students to vaccination against COVID-19 (motivation, possible problems, post-vaccination reactions).Цель исследования – определить отношение студентов-медиков к вакцинопрофилактике COVID-19 (мотивация, возможные проблемы, поствакцинальные реакции)

Pulseless disease

The article discusses a rare form of large vessel vasculitis – Takayasu arteritis, based on the literature data; the questions of epidemiological, the sequence of diagnostic procedures and treatment tactics are reflectedВ статье рассмотрена редкая форма васкулита крупных артерий - Артериит Такаясу, на основании литературных данных отражены вопросы эпидемиологии, последовательность проведения диагностических процедур и тактики лечени

Epidemiology of bloodstream infections in the burn icu

The study included data on 80 adult patients hospitalized in the ICU of the Yekaterinburg Burn Center in 2018 - 2019, who underwent at least one bacteriological blood test. In a small observational study, bloodstream infection did not lead to an increase in mortality, but is an important factor in increasing the incidence (length of hospitalization and ICU). In 70,5% of cases, the source of bloodstream infections are P. aeruginosa and S. aureus. The duration of standing of the CVC is one of the most important criteria for the development of bloodstream infectionsВ исследование включены данные о 80 взрослых пациентах, госпитализированных в ОРИТ ожогового центра Екатеринбурга в 2018 – 2019 гг, которым было сделано по крайней мере одно бактериологическое исследование крови. В небольшом обсервационном исследовании инфекция кровотока не привела к увеличению летальности, но является важным фактором увеличивающем заболеваемость (длительность госпитализации в стационаре и ОРИТ). В 70,5% случаев источником инфекций кровотока являются P. aeruginosa и S. aureus. Длительность стояния ЦВК один из важнейших критериев, обуславливающих развитие инфекций кровотока

The life and existential meaning of the personality of an oncological patient: a meaning analysis of concept

The article discusses the importance of personal psychological resource in the context of cancer. As such an internal resource, we have identified the vital and existential meanings, and we also determined the difference between these two concepts. The analysis of the literature has shown that one of the main problems of psychological science is search for psychological reasons for its loss and the possibility of finding meaning of life again and again rather than understanding it. We also found that a significant role in the acquisition and loss of meanings can be played by the personal qualities, personal attitude towards oneself, towards the world around, the ability to self-responsibility and to responsibility for own life.</jats:p

Role of vitamin D in formation of climacteric syndrome

Menopause is a physiological period during which involutional processes in the reproductive system predominate in a woman's body. Vitamin D deficiency increases the risk of age-related diseases, so it is important to examine and, if necessary, adjust the level of vitamin D. Purpose of the study. To determine the relationship between vitamin D levels and the severity of menopausal syndrome in postmenopausal women. Materials and methods. A cross-sectional study was conducted, which included data on 150 patients who applied for a gynecological appointment with complaints of manifestations of menopausal syndrome (CS). Results. As a result of the study, it was revealed that out of 150 women with manifestations of menopausal syndrome, the average level of 25(OH)D in the blood serum was 25.3(7.5) ng/ml. At the same time, in 49 (33%) of the surveyed, the content of hydroxyvitamin D was normal, a deficiency was observed in 53 (35%), and in 48 (32%), the indicators corresponded to a deficiency. However, the correlation analysis of the relationship between the level of vitamin D and the severity of the climacteric syndrome did not reveal a statistically significant relationship between the studied parameters (p=0.317). Conclusions. The severity of menopausal syndrome does not depend on the level of vitamin D in the blood, which confirms the leading role of hypoestrogenism in the etiopathogenesis of this condition.</jats:p

\kur{TUCUNARELLA} N. GEN. AND OTHER DACTYLOGYRIDS (MONOGENOIDEA) FROM CICHLID FISH (PERCIFORMES) FROM PERUVIAN AMAZONIA

Primary objectives: It has been proposed that dissociation plays a role in the aetiology of hallucinatory experiences. The present study examined the relationship between reports of auditory hallucinations and dissociative experiences in the daily lives of patients with psychosis. The influence of everyday stressors on dissociation and on the hypothesised relationship between dissociation and hallucinatory experiences was also investigated. Finally, this study examined the association between hallucinations and other non-dissociative dysfunctional strategies used to suppress unpleasant mental events (i.e. experiential avoidance). Method: Forty-two patients with a diagnosis of schizophrenia spectrum disorder and 23 healthy controls were studied for six days using the Experience Sampling Method (ESM), a structured self-assessment diary technique. Results: Patients who hallucinated during the assessment period (n = 21) reported elevated levels of dissociation compared to non-hallucinating patients and healthy controls. Within the hallucinating patient group, auditory hallucinations were significantly predicted by both dissociation and experiential avoidance, although only the effect of dissociation remained significant after controlling for comorbid paranoia. Dissociation predicted the occurrence of auditory hallucinations especially under high stress. Hallucinating patients also reported a greater increase in dissociation in response to minor daily life stress compared to clinical and non-clinical controls. Conclusions: These results further support the link between auditory hallucinations and experiences of dissociative detachment, and might inform future investigations into the mechanisms underlying this association. Interventions designed to reduce dissociation should be studied as potential treatments for auditory hallucinations