Morbidité et létalité palustres dans un service de pédiatrie en Afrique de l'Ouest

Le paludisme est à l'origine de 30 % des hospitalisations dans le service de pédiatrie de l'hôpital de Bobo-Dioulasso (Burkina Faso), avec une grande variation de fréquence au cours de l'année : 11 % des hospitalisations en saison sèche, 43 % en période de transmission palustre. Avec un taux de létalité de 7 %, le paludisme est directement responsable de 15 % des décès des enfants hospitalisés. (Résumé d'auteur

Assessment on experimental bacterial biofilms and in clinical practice of the efficacy of sampling solutions for microbiological testing of endoscopes

International audienceOpinions differ on the value of microbiological testing of endoscopes, which varies according to the technique used. We compared the efficacy on bacterial biofilms of sampling solutions used for the surveillance of the contamination of endoscope channels. To compare efficacy, we used an experimental model of a 48-h Pseudomonas biofilm grown on endoscope internal tubing. Sampling of this experimental biofilm was performed with a Tween 80-lecithin-based solution, saline, and sterile water. We also performed a randomized prospective study during routine clinical practice in our hospital sampling randomly with two different solutions the endoscopes after reprocessing. Biofilm recovery expressed as a logarithmic ratio of bacteria recovered on bacteria initially present in biofilm was significantly more effective with the Tween 80-lecithin-based solution than with saline solution (P = 0.002) and sterile water (P = 0.002). There was no significant difference between saline and sterile water. In the randomized clinical study, the rates of endoscopes that were contaminated with the Tween 80-lecithin-based sampling solution and the saline were 8/25 and 1/25, respectively (P = 0.02), and the mean numbers of bacteria recovered were 281 and 19 CFU/100 ml (P = 0.001), respectively. In conclusion, the efficiency and therefore the value of the monitoring of endoscope reprocessing by microbiological cultures is dependent on the sampling solutions used. A sampling solution with a tensioactive action is more efficient than saline in detecting biofilm contamination of endoscopes

Detection and Ranking of Vulnerable Areas to Urban Flooding Using GIS and ASMC (Spatial Analysis multicriteria): A Case Study in Dakar, Senegal

Dakar region is confronted in recent years with episodes of repetitive and devastating floods. The structures in charge of the matter, yet does not have enough knowledge of space and tools to preciselylocate vulnerable areas. It is in this particular context that we have through this study process by coupling GIS and ASMC techniques. We aim in this coupling, to develop an efficient tool for support decision making in terms of identification strategies, intervention or adaptation. The defined criteria for this are: the rainfall, the groundwater level, geology, topography, wetlands, population density, living standards and the type of habitat. We have used an analytical hierarchical process (AHP) by foursteps: a) the breakdown of problematic vulnerabilities; b) scanning and harmonization of layers factors (criteria); c) the weight assignment of different layers criteria according to the comparison procedure in pairs; d) and aggregation criteria layers, through the weighted superposition of the SOC software tool. This has helped us to hierarchically locate the vulnerable are as to flooding. The results have showed a very low vulnerability (1.67%), low vulnerability (50.53%), high vulnerability (43.66%) and a very high vulnerability (4.14%). Approximately, 50% of the Dakar region are vulnerable to flooding and particularly the suburban area concerning the departments of Pikine and Guediawaye. These informations are very useful for governments in the effective and sustainable flood management and identification of priority intervention areas

Induced molecular dissociations as a radiation damage descriptor: nanodosimetry

Conferencia invitada; IBER 2015, 6-9th September, Aveiro – Portugal; http://iber2015.web.ua.pt/Traditional dosimetry is based on the proportionality between the energy absorbed by the medium (absorbed dose) and the induced damage. This assumption applies for relatively high irradiated volumes and requires some equilibrium conditions. However, for small volumes being relatively far from the central irradiated areas these conditions are not observed and radiation damage is mainly driven by low energy secondary species (electrons and radicals) which induce molecular dissociations via electronic and vibrational excitations, electron attachment and chemical reactions. We will present here an integrated modelling procedure to simulate particle radiation tracks including those of all generated secondary species and their further interactions with the molecular constituent of the medium. For any selected volume of interest, this model provides not only the total energy transferred to that area but also the number and type of interactions taking place in it [1].Peer Reviewe

Les aspects parasitologiques de l'épidémiologie du paludisme dans le Sahara malien

Dans le cadre de l'évaluation épidémiologique de la Transsaharienne, une enquête transversale paludométrique a été réalisée d'Août 1988 à Septembre 1988 le long du tronçon malien. Neuf localités ont été visitées : Douentza, Gossi, Bourem, Almoustarat, Anefis, Aguel-Hoc, Tarlit, Tessalit, Kidal, Bouressa. 2185 unités ont été prélevées pour les études cliniques, parasitologiques et immunologiques. L'indice plasmodique global est de 5,3 % avec une grande variation du Sud (44,6 %) au Nord (0 %). L'indice gamétocytique et l'indice splénique sont très faibles. #P. falciparum est l'espèce dominante. #P. malariae a été décrit une fois en association avec #P. falciparum. #P. ovale n'a jamais été observé. Par contre un cas de #P. vivax a été décrit chez une jeune fille leucoderme de 8 ans à Kidal. #A. gambiae s.s. (forme Mopti) et #A. arabiensis sont les principaux vecteurs au Nord du Mali. Une hypothèse de circulation de #P. vivax dans le Sahara malien est émise. (Résumé d'auteur