145 research outputs found
Fast ReRoute on Programmable Switches
Highly dependable communication networks usually rely on some kind of Fast Re-Route (FRR) mechanism which allows to quickly re-route traffic upon failures, entirely in the data plane. This paper studies the design of FRR mechanisms for emerging reconfigurable switches. Our main contribution is an FRR primitive for programmable data planes, PURR, which provides low failover latency and high switch throughput, by avoiding packet recirculation. PURR tolerates multiple concurrent failures and comes with minimal memory requirements, ensuring compact forwarding tables, by unveiling an intriguing connection to classic ``string theory'' (i.e., stringology), and in particular, the shortest common supersequence problem. PURR is well-suited for high-speed match-action forwarding architectures (e.g., PISA) and supports the implementation of a broad variety of FRR mechanisms. Our simulations and prototype implementation (on an FPGA and a Tofino switch) show that PURR improves TCAM memory occupancy by a factor of 1.5x-10.8x compared to a naĂŻve encoding when implementing state-of-the-art FRR mechanisms. PURR also improves the latency and throughput of datacenter traffic up to a factor of 2.8x-5.5x and 1.2x-2x, respectively, compared to approaches based on recirculating packets
Electron Micrographs of the Nematocysts of Hydra
Seventeen different kinds of nematocysts have been described and classified by Weill (1930) on the basis of the characteristics of the discharged tube. Only four of these are known to be present on hydras, namely, volvents (desmonemes), streptoline glutinants (holotrichous isorhizas), stereoline glutinants (atrichous isorhizes), and penetrants (stenoteles). The discharged penetrant (fig. 1) consists of the capsule a, butt, which is composed of the shaft b, stylet c, spinneret d, and tube e. In the glutinants the tube is attached directly to the tube, and is either spiny (streptoline glutinant) or smooth (stereoline glutinant). In the resting nematocyst all the component parts are inverted and contained within the capsule
Considerations for management strategy evaluation for small pelagic fishes
Management strategy evaluation (MSE) is the state-of-the-art approach for testing and comparing management strategies in a way that accounts for multiple sources of uncertainty (e.g. monitoring, estimation, and implementation). Management strategy evaluation can help identify management strategies that are robust to uncertainty about the life history of the target species and its relationship to other species in the food web. Small pelagic fish (e.g. anchovy, herring and sardine) fulfil an important ecological role in marine food webs and present challenges to the use of MSE and other simulation-based evaluation approaches. This is due to considerable stochastic variation in their ecology and life history, which leads to substantial observation and process uncertainty. Here, we summarize the current state of MSE for small pelagic fishes worldwide. We leverage expert input from ecologists and modellers to draw attention to sources of process and observation uncertainty for small pelagic species, providing examples from geographical regions where these species are ecologically, economically and culturally important. Temporal variation in recruitment and other life-history rates, spatial structure and movement, and species interactions are key considerations for small pelagic fishes. We discuss tools for building these into the MSE process, with examples from existing fisheries. We argue that model complexity should be informed by management priorities and whether ecosystem information will be used to generate dynamics or to inform reference points. We recommend that our list of considerations be used in the initial phases of the MSE process for small pelagic fishes or to build complexity on existing single-species models.publishedVersio
Sex-Specific Growth and Reproductive Dynamics of Red Drum in the Northern Gulf of Mexico
The Red Drum Sciaenops ocellatus stock is heavily targeted in the Gulf of Mexico (GOM) by recreational fishers and supports a small commercial fishery in Mississippi. Despite their popularity, little recent work has been done to describe their life history. In this work, we describe sexâspecific growth and reproductive dynamics of Red Drum collected from the northern GOM from September 2016 through October 2017. We evaluated seven candidate growth models and found that the threeâparameter von Bertalanffy growth function (VBGF) was the best candidate lengthâatâage model. No significant difference in growth between sexes was observed with the threeâparameter VBGF, despite the femaleâspecific curve having a larger mean asymptotic length than the maleâspecific curve. All seven candidate growth models predicted similar mean lengthâatâage estimates, and four of them exhibited significant differences in sexâspecific mean length at age, with females reaching a larger length at age than males after age 5. There was no significant difference between the sexâspecific weightâatâlength relationships. Red Drum are batch spawners that spawn in northern GOM coastal waters during August and September. We estimated 3.7 d between spawns and 10.5 spawning events per female in 2017. Nearly 20% of fish collected during the spawning season were sexually mature but reproductively inactive, indicating the possibility of skipped spawning. The age at 50% maturity was around 3 years (length at 50% maturity = 670 mm TL) in both sexes, but fish were not spawning capable until age 4.5 (703 mm TL) in males and age 5.8 (840 mm TL) in females. Furthermore, elevated gonadosomatic indices were not observed until around age 5â6. The updated life history information presented in this work helps to address current data limitations and provides critical information for future assessments of Red Drum stocks in the northern GOM
Comprehensive Analysis Reveals Dynamic and Evolutionary Plasticity of Rab GTPases and Membrane Traffic in Tetrahymena thermophila
Cellular sophistication is not exclusive to multicellular organisms, and unicellular eukaryotes can resemble differentiated animal cells in their complex network of membrane-bound structures. These comparisons can be illuminated by genome-wide surveys of key gene families. We report a systematic analysis of Rabs in a complex unicellular Ciliate, including gene prediction and phylogenetic clustering, expression profiling based on public data, and Green Fluorescent Protein (GFP) tagging. Rabs are monomeric GTPases that regulate membrane traffic. Because Rabs act as compartment-specific determinants, the number of Rabs in an organism reflects intracellular complexity. The Tetrahymena Rab family is similar in size to that in humans and includes both expansions in conserved Rab clades as well as many divergent Rabs. Importantly, more than 90% of Rabs are expressed concurrently in growing cells, while only a small subset appears specialized for other conditions. By localizing most Rabs in living cells, we could assign the majority to specific compartments. These results validated most phylogenetic assignments, but also indicated that some sequence-conserved Rabs were co-opted for novel functions. Our survey uncovered a rare example of a nuclear Rab and substantiated the existence of a previously unrecognized core Rab clade in eukaryotes. Strikingly, several functionally conserved pathways or structures were found to be associated entirely with divergent Rabs. These pathways may have permitted rapid evolution of the associated Rabs or may have arisen independently in diverse lineages and then converged. Thus, characterizing entire gene families can provide insight into the evolutionary flexibility of fundamental cellular pathways
Anti-Staphylococcus aureus activity of methanol extracts of 12 plants used in Cameroonian folk medicine
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