Effect of heat treatment on the wear and corrosion behaviors of a gray cast iron coated with a COLMONOY 88 alloy deposited by high velocity oxygen fuel (HVOF) thermal spray

The present work has been conducted in order to determine the influence of heat treatment on the wear and corrosion behaviours of a gray cast iron substrate coated with a Ni base coating deposited by HVOF thermal spray. The wear resistance of the coatings was obtained using a reciprocating wear tester by rubbing a 10 mm diameter steel ball on the coatings at normal atmospheric conditions. Corrosion tests were performed using potentiodynamic polarization measurements in a 3,5 % NaCl solution. It was observed that the corrosion and wear resistance of the coatings increased along with the reduction of porosity and roughness by the heat treatment

A Survey of Bayesian Statistical Approaches for Big Data

The modern era is characterised as an era of information or Big Data. This has motivated a huge literature on new methods for extracting information and insights from these data. A natural question is how these approaches differ from those that were available prior to the advent of Big Data. We present a review of published studies that present Bayesian statistical approaches specifically for Big Data and discuss the reported and perceived benefits of these approaches. We conclude by addressing the question of whether focusing only on improving computational algorithms and infrastructure will be enough to face the challenges of Big Data

The ARID1B spectrum in 143 patients: from nonsyndromic intellectual disability to Coffin–Siris syndrome

Purpose: Pathogenic variants in ARID1B are one of the most frequent causes of intellectual disability (ID) as determined by large-scale exome sequencing studies. Most studies published thus far describe clinically diagnosed Coffin–Siris patients (ARID1B-CSS) and it is unclear whether these data are representative for patients identified through sequencing of unbiased ID cohorts (ARID1B-ID). We therefore sought to determine genotypic and phenotypic differences between ARID1B-ID and ARID1B-CSS. In parallel, we investigated the effect of different methods of phenotype reporting. Methods: Clinicians entered clinical data in an extensive web-based survey. Results: 79 ARID1B-CSS and 64 ARID1B-ID patients were included. CSS-associated dysmorphic features, such as thick eyebrows, long eyelashes, thick alae nasi, long and/or broad philtrum, small nails and small or absent fifth distal phalanx and hypertrichosis, were observed significantly more often (p < 0.001) in ARID1B-CSS patients. No other significant differences were identified. Conclusion: There are only minor differences between ARID1B-ID and ARID1B-CSS patients. ARID1B-related disorders seem to consist of a spectrum, and patients should be managed similarly. We demonstrated that data collection methods without an explicit option to report the absence of a feature (such as most Human Phenotype Ontology-based methods) tended to underestimate gene-related features

Guidelines for postoperative care in gynecologic/oncology surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations - Part II.

This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text via the publisher's site.Published (Open Access

Immobilization of lipases on different carriers and their use in synthesis of pentyl isovalerates

WOS: 000221864500005PubMed ID: 15195711Porcine pancreatic lipase (PPL) and Candida cylindracea lipase (CCL) were immobilized on Celite and Amberlite IRA 938 by deposition from the aqueous solution by the addition of hexane. The influence of the immobilization on the activities of the immobilized lipase derivatives has been studied. The immobilized lipases were used in synthesis of pentyl isovalerates. Various reaction parameters affecting the synthesis of pentyl isovalerates were investigated. The reaction rates were compared with the rates of esterification with free lipases. The immobilized lipases were found to be very effective in the esterification reaction. The lipases immobilized on Celite 545 exhibited better operational stabilities than that of immobilized on Amberlite IRA-938

A new species of Scorzonera (Asteraceae) from Anatolia, Turkey

WOS: 000182917200007Scorzonera aytatchii sp. nov. is described from the Aydos Mountain (C4: Konya) in Turkey. It is related to S. rigida, from which it mainly differs in its hairy achene

THE INVESTIGATION OF THE STRENGTH REDUCTION FACTOR IN PREDICTING THE SHEAR STRENGTH

Design codes propose to restrict the nominal probability of failure within specific target structural reliability levels using a load factor and a strength reduction factor. In the current ACI318 Code, the strength reduction factor varies from 0.65 to 0.90, and the value considered in predicting the shear strength equals to 0.75. In this study, the change in the strength reduction factor in predicting the shear strength according to ACI318 has been investigated for different coefficients of variation of concrete compressive strength by using the first-order second moment approach, and the strength reduction factor is proposed for the target values of failure probability

The investigation of the strength reduction factor in predicting the shear strength

Design codes propose to restrict the nominal probability of failure within specific target structural reliability levels using a load factor and a strength reduction factor. In the current ACI318 Code, the strength reduction factor varies from 0.65 to 0.90, and the value considered in predicting the shear strength equals to 0.75. In this study, the change in the strength reduction factor in predicting the shear strength according to ACI318 has been investigated for different coefficients of variation of concrete compressive strength by using the first-order second moment approach, and the strength reduction factor is proposed for the target values of failure probability