Primary Cutaneous Large B-Cell Lymphoma, Leg Type, Localized on the Dorsum

Primary cutaneous large B-cell lymphoma, leg-type (PCLBCL-LT), is a large B-cell lymphoma primarily involving the skin. It is distinguished from the other 3 subsets of this lymphoproliferative disorder by its immunohistopathological features, configuring confluent sheets of medium-sized to large B lymphocytes with round nuclei provided with evident nucleoli, resembling centroblasts or immunoblasts, which express Bcl-6, Bcl-2. Prevalently appearing on the lower limbs, as a single or multicentric and frequently ulcerated skin nodule or plaque, PCLBCL-LT has a worse prognosis than the other large B-cell lymphomas. Moreover, the age of onset is delayed (7th decade) compared to those of the other 3 subtypes (6th decade); it presents a slight female predominance (2:1), and a higher percentage of positivity to Bcl-2. We present a 52-year-old man who showed a 2-year standing, non-ulcerated, round, 4 cm in diameter, red plaque, medially located on the dorsum. After biopsy the diagnosis of PCLBCL-LT was made on histopathological and immunohistochemical studies, the latter showing positivity to CD20, Bcl-2, and Bcl-6. After treatment with radiotherapy the patient has shown a 4.4-year follow-up free of disease

Evaluation HPDC Lubricant Spraying for Improved Cooling and Die Protection

This study tries to find out a better cooling and temperature homogenization as well as better die protection on high-pressure die-casting (HPDC) spray lubrication. Test procedures have been set up to study the Leidenfrost point (LFP), contact angle (CA), film thickness and protection from die soldering of lubricants typically applied into the die surfaces during HPDC process. Five different lubricants have been studied as well as the influence in different controllable process parameters (type of die material, oxidation of the surface, temperature, roughness, droplet diameter, water hardness and lubricant concentration). The increase of the LFP, avoiding film boiling regime, and a reduced CA, improve the cooling and film ability of die surface during spraying. The best chemistry exhibits high LFP, shows an increased thickness of the formed film and is more effective preventing the sticking of the aluminum part to the die surface. Thermogravimetric analysis shows better thermal properties for lubricants with anti-sticking performance. The study performed and the test protocols set up result in a better insight of the involved phenomena and allow selecting the most favorable operating window for HPDC lubrication

Salicylic Acid Peel Incorporating Triethyl Citrate and Ethyl Linoleate in the Treatment of Moderate Acne: A New Therapeutic Approach.

BACKGROUND: Acne affects many adolescents. Conventional therapy often results in side effects and poor adherence, and the treatment does not consider the psychological effect of acne on patients, which is comparable with that of disabling diseases. OBJECTIVES: To evaluate the efficacy and tolerability of a peel (30% salicylic acid, triethyl citrate and ethyl linoleate) combined with a home therapy with three topical agents (triethyl citrate, ethyl linoleate and salicylic acid 0.5% cream, lotion) in moderate acne of the face. DESIGN: Prospective, observational, multicenter, open-label, postmarketing, phase IV study. METHODS: Patients were assessed by comparing Global Acne Grading System (GAGS) score and total lesion count from 15 days before the first peel (T-15 ), after four salicylic peels (every 10 ± 2 days (T0 , T10 , T20 , T30 ), and 20 days after of the end of the study (T50 ). This treatment was associated to a home therapy. RESULTS: Fifty-three patients completed the study. The average GAGS score fell 49% between T-15 and T50 (p < .001). No patient withdrew for adverse events. CONCLUSIONS: This therapy was effective and well-tolerated in all cases. Chemo-exfoliation sessions ensured the continuous monitoring of clinical results and improved patient quality of life

Molossus rufus: distribuição geográfica e primeiro registro para Sergipe, nordeste do Brasil

Distributed throughout the world, Molossidae family consists of 18 genera and more than 100 species, 31 of which are found in Brazil. In this country, most of the records of Molossus rufus were taken in the southeast of the Atlantic Forest, with few records in the Cerrado and Caatinga. This study reports the first record of Molossus rufus for the state of Sergipe, northeastern Brazil. One lactating female was captured by mist nets, near buildings, in the Ibura National Forest (FLONA Ibura), in the beginning of the rainy season. This is the third species of molossid recorded to the state of Sergipe; the other two (Molossus molossus and Cynomops planirostris) were also recorded in human buildings.Keywords: Atlantic Forest, bats, Molossidae.Distribuída em todo o mundo, a família Molossidae consiste em 18 gêneros e mais de 100 species, 31 delas encontradas no Brasil. Nesse país, a maioria dos registros de Molossus rufus foi realizada no sudeste da Mata Atlântica, com poucos registros no Cerrado e Caatinga. Este estudo relata o primeiro registro de Molossus rufus para o estado de Sergipe, nordeste do Brasil. Uma fêmea lactante foi capturada com redes de neblina, próximo a edificações, na Floresta Nacional do Ibura (FLONA Ibura), no início da estação chuvosa. Esta é a terceira espécie de molossídeo registrada no estado de Sergipe, sendo que as outras duas (Molossus molossus e Cynomops planirostris) também foram registradas em construções humanas.Palavras-chave: Mata Atlântica, morcegos, Molossidae

Levantamentos rápidos como ferramenta-chave para o inventário da fauna de morcegos do Brasil: novos registros na restinga costeira

The restingas present a considerable variation in the floristic structure and composition along their latitudinal and morphoclimatic gradients. This variation may have a direct influence on the set of conditions and resources available for their biological communities, including mammals. The present study is the first to assess the bat fauna of a coastal restinga habitat in northeastern Brazil. The study site was the RPPN Caju in the municipality of Itaporanga D’Ajuda, Sergipe. We collected data on 10 consecutive days in 2014, using mist nets set at ground level, sampling a different point on each day. We captured 191 bats (16 species, 14 genera and 5 families), including the first records of Saccopteryx leptura, Molossops temminckii and Eptesicus brasiliensis for the coastal restinga. The latter two species were recorded for Sergipe for the first time. The recorded species richness is one of the highest yet recorded for Brazilian restinga. We increased the number of records of bat species in the Brazilian restinga from 38 to 41, and the number of species known to occur in Sergipe from 48 to 50. We recommend the “wandering” placement of mist nets as an effective strategy for the rapid assessment of bat communities.Keywords: Chiroptera, Eptesicus brasiliensis, Molossops temminckii, Saccopteryx leptura, Sergipe.As restingas apresentam considerável variação na composição e estrutura florística ao longo do seu gradiente latitudinal e morfoclimático. Essa variação pode ter influência direta no conjunto de condições e recursos disponíveis para suas comunidades biológicas, incluindo os mamíferos. O presente estudo é o primeiro a avaliar a quiropterofauna da restinga do nordeste brasileiro. O local de estudo foi a RPPN Caju, no município de Itaporanga D’Ajuda, Sergipe. Foram realizados 10 dias consecutivos de amostragem, em 2014, usando redes de neblina no nível do solo. Em cada dia, foram amostrados pontos diferentes. Foram capturados 191 morcegos (16 espécies, 14 gêneros e 5 famílias), com destaque para os primeiros registros de Saccopteryx leptura, Molossops temminckii e Eptesicus brasiliensis para a restinga. As duas últimas espécies são registradas pela primeira vez para Sergipe. A riqueza registrada na RPPN representa uma das mais altas registradas na literatura para a restinga. Ampliamos o número de registros de espécies de morcegos para a restinga de 38 para 41, e o número de espécies conhecidas para Sergipe de 48 para 50. Recomenda-se a instalação errante de redes de neblina para avaliações rápidas das comunidades de morcegos.Palavras-chave: Chiroptera, Eptesicus brasiliensis, Molossops temminckii, Saccopteryx leptura, Sergipe

ATLANTIC-PRIMATES: a dataset of communities and occurrences of primates in the Atlantic Forests of South America

Primates play an important role in ecosystem functioning and offer critical insights into human evolution, biology, behavior, and emerging infectious diseases. There are 26 primate species in the Atlantic Forests of South America, 19 of them endemic. We compiled a dataset of 5,472 georeferenced locations of 26 native and 1 introduced primate species, as hybrids in the genera Callithrix and Alouatta. The dataset includes 700 primate communities, 8,121 single species occurrences and 714 estimates of primate population sizes, covering most natural forest types of the tropical and subtropical Atlantic Forest of Brazil, Paraguay and Argentina and some other biomes. On average, primate communities of the Atlantic Forest harbor 2 ± 1 species (range = 1–6). However, about 40% of primate communities contain only one species. Alouatta guariba (N = 2,188 records) and Sapajus nigritus (N = 1,127) were the species with the most records. Callicebus barbarabrownae (N = 35), Leontopithecus caissara (N = 38), and Sapajus libidinosus (N = 41) were the species with the least records. Recorded primate densities varied from 0.004 individuals/km 2 (Alouatta guariba at Fragmento do Bugre, Paraná, Brazil) to 400 individuals/km 2 (Alouatta caraya in Santiago, Rio Grande do Sul, Brazil). Our dataset reflects disparity between the numerous primate census conducted in the Atlantic Forest, in contrast to the scarcity of estimates of population sizes and densities. With these data, researchers can develop different macroecological and regional level studies, focusing on communities, populations, species co-occurrence and distribution patterns. Moreover, the data can also be used to assess the consequences of fragmentation, defaunation, and disease outbreaks on different ecological processes, such as trophic cascades, species invasion or extinction, and community dynamics. There are no copyright restrictions. Please cite this Data Paper when the data are used in publications. We also request that researchers and teachers inform us of how they are using the data. © 2018 by the The Authors. Ecology © 2018 The Ecological Society of Americ

Intralesional steroid injections to target sinus tract fibrosis in hidradenitis suppurativa: Results from an ultrasound-based retrospective study

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