Pengaruh Model Pembelajaran Talking Stick terhadap Keaktifan Belajar Siswa

[Title: The Effect of a Talking Stick Learning Model on Student Learning Activities]. A fun learning environment, active and meaningful for students need to be created by applying active learning model for students that learning model talking stick. This type of research is quasi-experimental. This research aimed to know there is or no effect of talking stick learning model toward students learning activeness. This research implemented in class VIII SMP Negeri 5 Mataram in academic year 2015/2016 from March to April 2016. The technique of sample using cluster random sampling, in order to obtain first-class VIII I totalling 30 students as an experimental class and class VIII E totalling 30 students as the control class. The results of this research are students' activeness learning showed by using the instrument is activeness of student learning questionnaire. Based on data analysis showed that t-test was 8.28 and t- table was 2.000 (df = 58). So, t-test > t-table (8.28 > 2.000). This means that there is an effect of talking stick learning model toward students learning activeness

EPR and optical spectroscopy of Yb3+ ions in CaF2 and SrF2

Yb3+ paramagnetic center of trigonal symmetry in CaF2 and SrF2 and SrF2 single crystals was studied using electron paramagnetic resonance and optical spectroscopy. Stark level energies of the Yb3+ multiplets were established from absorption, luminescence and excitation luminescence spectra and crystal field parameters were calculated. It was found that the obtained crystal field parameters decreased as the lattice constant increased

EPR and optical spectroscopy of SrF2 doped with Yb3+

The trigonal paramagnetic Yb3+ ion in SrF2 is investigated. The analysis used EPR and optical spectroscopy. The energy level scheme of the center is determined from its optical spectra and the parameters of the crystal field potential are calculated

Multi-periodic photospheric pulsations and connected wind structures in HD64760

We report on the results of an extended optical spectroscopic monitoring campaign on the early-type B supergiant HD64760 (B0.5Ib) designed to probe the deep-seated origin of spatial wind structure. This new study is based on high-resolution echelle spectra obtained with the FEROS instrument at ESO La Silla. 279 spectra were collected over 10 consecutive nights in 2003. From the period analysis of the line-profile variability of the photospheric lines we identify three closely spaced periods around 4.810 hrs and a splitting of +/-3%. The velocity - phase diagrams of the line-profile variations for the distinct periods reveal characteristic prograde non-radial pulsation patterns of high order corresponding to pulsation modes with l and m in the range 6-10. The three pulsation modes have periods clearly shorter than the characteristic pulsation time scale and show small horizontal velocity fields and hence are identified as p-modes. The beating of the three pulsation modes leads to a retrograde beat pattern with two regions of constructive interference diametrically opposite on the stellar surface and a beat period of 162.8hrs (6.8days). This beat pattern is directly observed in the spectroscopic time series of the photospheric lines. The wind-sensitive lines display features of enhanced emission, which appear to follow the maxima of the photospheric beat pattern.Comment: 18 pages, 21 figures (reduced resolution

The Mitochondrial Complex(I)ty of Cancer

Recent evidence highlights that the cancer cell energy requirements vary greatly from normal cells and that cancer cells exhibit different metabolic phenotypes with variable participation of both glycolysis and oxidative phosphorylation. NADH–ubiquinone oxidoreductase (Complex I) is the largest complex of the mitochondrial electron transport chain and contributes about 40% of the proton motive force required for mitochondrial ATP synthesis. In addition, Complex I plays an essential role in biosynthesis and redox control during proliferation, resistance to cell death, and metastasis of cancer cells. Although knowledge about the structure and assembly of Complex I is increasing, information about the role of Complex I subunits in tumorigenesis is scarce and contradictory. Several small molecule inhibitors of Complex I have been described as selective anticancer agents; however, pharmacologic and genetic interventions on Complex I have also shown pro-tumorigenic actions, involving different cellular signaling. Here, we discuss the role of Complex I in tumorigenesis, focusing on the specific participation of Complex I subunits in proliferation and metastasis of cancer cells

Progressive multifocal leukoencephalopathy in a patient without apparent immunosuppression

An 80-year-old man with no history of an immune-compromising disorder was diagnosed with progressive multifocal leukoencephalopathy (PML). He presented with dysphagia and left-sided weakness; magnetic resonance imaging demonstrated marked signal abnormality in the subcortical white matter of the left frontal lobe and in the posterior limb of the right internal capsule. Polymerase chain reaction (PCR) analysis of the cerebrospinal fluid (CSF) was negative for John Cunningham (JC) virus. On brain biopsy, foamy macrophages infiltrating the white matter were identified, staining positive for anti-simian virus 40 antibodies. Postoperatively, PCR for JC viral DNA in the CSF was positive, establishing the diagnosis of PML. Extensive investigation for an occult immunocompromising disorder was negative. The patient's neurologic deficits rapidly increased throughout his hospital stay, and he died 3.5 months after his diagnosis

Long-term spectroscopic monitoring of the Luminous Blue Variable HD160529

We have spectroscopically monitored the galactic Luminous Blue Variable HD 160529 and obtained an extensive high-resolution data set that covers the years 1991 to 2002. During this period, the star evolved from an extended photometric minimum phase towards a new visual maximum. In several observing seasons, we covered up to four months with almost daily spectra. Our spectra typically cover most of the visual spectral range with a high spectral resolution (about 20,000 or more). This allows us to investigate the variability in many lines and on many time scales from days to years. We find a correlation between the photospheric HeI lines and the brightness of the star, both on a time scale of months and on a time scale of years. The short-term variations are smaller and do not follow the long-term trend, strongly suggesting different physical mechanisms. Metal lines also show both short-term and long-term variations in strength and also a long-term trend in radial velocity. Most of the line-profile variations can be attributed to changing strengths of lines. Propagating features in the line profiles are rarely observed. We find that the mass-loss rate of HD 160529 is almost independent of temperature, i.e. visual brightness.Comment: 14 pages, 15 figures, accepted for publication in Astronomy & Astrophysic

Antimicrobial activity and bioactive compounds of portuguese wild edible mushrooms methanolic extracts

The antimicrobial properties of phenolic extracts of Portuguese wild edible mushroom species (Lactarius deliciosus, Sarcodon imbricatus and Tricholoma portentosum) against pathogens were investigated. The minimal inhibitory concentrations (MICs) were evaluated for the entire mushroom, the cap and the stipe, separately; the portion of the mushroom used proved to be influenced in the results obtained, which are directly correlated with the content of total phenols and flavonoids in the extracts. The growth of Grampositive bacteria (Bacillus cereus, B. subtilis,) was well inhibited by these mushrooms, while Escherichia coli (Gramnegative bacteria) was resistant. The study on the antifungal effect of these mushrooms revealed that Candida albicans and Cryptococcus neoformans were differently inhibited for the mushrooms used

Bibliometric Evidence for a Hierarchy of the Sciences

The hypothesis of a Hierarchy of the Sciences, first formulated in the 19(th) century, predicts that, moving from simple and general phenomena (e.g. particle dynamics) to complex and particular (e.g. human behaviour), researchers lose ability to reach theoretical and methodological consensus. This hypothesis places each field of research along a continuum of complexity and "softness", with profound implications for our understanding of scientific knowledge. Today, however, the idea is still unproven and philosophically overlooked, too often confused with simplistic dichotomies that contrast natural and social sciences, or science and the humanities. Empirical tests of the hypothesis have usually compared few fields and this, combined with other limitations, makes their results contradictory and inconclusive. We verified whether discipline characteristics reflect a hierarchy, a dichotomy or neither, by sampling nearly 29,000 papers published contemporaneously in 12 disciplines and measuring a set of parameters hypothesised to reflect theoretical and methodological consensus. The biological sciences had in most cases intermediate values between the physical and the social, with bio-molecular disciplines appearing harder than zoology, botany or ecology. In multivariable analyses, most of these parameters were independent predictors of the hierarchy, even when mathematics and the humanities were included. These results support a "gradualist" view of scientific knowledge, suggesting that the Hierarchy of the Sciences provides the best rational framework to understand disciplines' diversity. A deeper grasp of the relationship between subject matter's complexity and consensus could have profound implications for how we interpret, publish, popularize and administer scientific research

Participation of Actin on Giardia lamblia Growth and Encystation

BACKGROUND:Microfilaments play a determinant role in different cell processes such as: motility, cell division, phagocytosis and intracellular transport; however, these structures are poorly understood in the parasite Giardia lamblia. METHODOLOGY AND PRINCIPAL FINDINGS:By confocal microscopy using TRITC-phalloidin, we found structured actin distributed in the entire trophozoite, the label stand out at the ventral disc, median body, flagella and around the nuclei. During Giardia encystation, a sequence of morphological changes concurrent to modifications on the distribution of structured actin and in the expression of actin mRNA were observed. To elucidate whether actin participates actively on growth and encystation, cells were treated with Cytochalasin D, Latrunculin A and Jasplakinolide and analyzed by confocal and scanning electron microscopy. All drugs caused a growth reduction (27 to 45%) and changes on the distribution of actin. Besides, 60 to 80% of trophozoites treated with the drugs, exhibited damage at the caudal region, alterations in the flagella and wrinkles-like on the plasma membrane. The drugs also altered the cyst-yield and the morphology, scanning electron microscopy revealed diminished cytokinesis, cysts with damages in the wall and alterations in the size and on the intermembranal space. Furthermore, the drugs caused a significant reduction of the intensity of fluorescence-labeled CWP1 on ESV and on cyst wall, this was coincident with a reduction of CWP1 gene expression (34%). CONCLUSIONS AND SIGNIFICANCE:All our results, indicated an important role of actin in the morphology, growth and encystation and indirectly suggested an actin role in gene expression