El burn-out y su impacto en los docentes de la Facultad de Contaduría Pública y Administración, Universidad Autónoma de Nuevo León = (The burn-out and its impact on teachers of the school of accounting and business administration, University of Nuevo León)

Resumen: Existen estudios que muestran que las personas en contacto permanente con otras personas llegan a mostrar alto cansancio emocional, despersonalización y baja realización personal conocidas como Burn-out (Síndrome de Quemado por el Trabajo SQT). Este síndrome puede presentarse entre individuos que trabajan con personas al exigir de ellos un desempeño laboral. Este esfuerzo genera en el recurso humano diferentes alteraciones y desgastes físicos y psicológicos que disminuyen el rendimiento laboral, repercutiendo no solo a nivel operativo y administrativo, también se refleja en la conducta del individuo así como en su estado anímico, reflejo que denota estrés laboral el cual es considerado clínicamente como Síndrome del Burn-out. Si analizamos el SQT de los docentes desde un enfoque de administración del capital humano, podemos medir el impacto en la calidad y eficiencia de las universidades. Razón por la cual, en ésta investigación se explorará básicamente: ¿En qué grado los docentes activos de la Facultad de Contaduría Pública y Administración (FACPyA) de la Universidad Autónoma de Nuevo León (UANL) padecen el síndrome de SQT?, conocer si la edad, el género y tener pareja son factores que se relacionan en sujetos que padecen el síndrome de SQT, así como saber si la antigüedad laboral, la satisfacción laboral y las relaciones laborales entre los sujetos de la investigación tienen algún grado significativo de relación con los niveles de SQT. Por lo tanto, esta investigación, tiene como objetivo conocer y describir mediante un estudio de análisis descriptivo, el impacto que tiene la sobrecarga de estrés en los docentes de la FACPyA de la UANL. Abstract: The teachers in permanent contact with persons manage to show high emotional weariness, despersonalization and low personal accomplishment known as Burn-out (Syndrome of Burned by the Work SQT) that can appear between individuals who work with persons on having demanded of them a labor performance. This syndrome from an approach of administration of the human capital, affects the quality and efficiency of the organizations. In this one investigation will be explored basically: in what degree do the active teachers of the Faculty of Public Accountancy and Administration (FACPyA) of the Autonomous University again León (UANL) suffer SQT's syndrome? Are the age, the kind and to have pair factors that relate in subjects that suffer SQT's syndrome? ¿Have the labor antiquity, the labor satisfaction and the labor relations between the subjects of the investigation some significant degree of relation with SQT's levels? This effort generates in the human resource different alterations and physical and psychological wears that diminish the labor performance, reverberating not only to operative and administrative level, also is reflected in the conduct of the individual as well as in his mental condition, reflection that denotes job stress which is considered to be clinical A Syndrome of the Burn-out (Syndrome of Burned by the Work SQT). This investigation, it has as aim know and describe by means of a study of descriptive analysis, the impact that has the overload of stress in the teachers of the FACPyA of the UANL. Key words: Syndrome Burned by the Work (SQT), stress, teachers

Coexistence of antiferro- and ferrimagnetism in the spinel ZnFe2O4 with an inversion degree d lower than 0.3

Samples with inversion parameter values (d) ranging from 0.27 to 0.14 while maintaining the crystallite size value have been successfully fabricated from commercially available powders by mechanical grinding and thermal annealing treatments at temperatures ranging between 400 and 600 °C. Detailed characterization studies of these samples using X-ray, neutron diffraction and magnetic measurements have confirmed for the first time the simultaneous coexistence at 2 K of short range antiferromagnetic and ferrimagnetic ordering for a wide range of the inversion parameter. The magnetic phase diagram obtained is different from the one previously reported, which shows at 2 K the coexistence of long range antiferromagnetic order and short range order for values of inversion parameters less than 0.1 and the presence of a ferrimagnetic order only for values of d > 0.2. At room temperature, the Rietveld analysis of NPD patterns and the magnetization curves showed a paramagnetic behavior in the samples with d = 0.1. For the samples with higher cationic inversion, typical hysteresis curves of ferrimagnetic materials were observed and the saturation magnetization values obtained agree quite well with the net magnetic moment obtained from the Rietveld refinement of the neutron diffraction patterns. © 202

In vitro gastrointestinal digestion of microencapsulated extracts of Flourensia cernua, F. microphylla, and F. retinophylla

Recently, some species of the genus Flourensia have been identified by their potential health effects (e.g. anti-inflammatory and apoptotic). Encapsulation of plant extracts is a process that can allow an adequate dosage administration, as well as to protect bioactive compounds and improve their controlled release in the gastrointestinal (GI) system. Therefore, the aims of this work were: to microencapsulate the ethanol extracts of F. cernua, F. microphylla, and F. retinophylla; and to evaluate the controlled release of the microencapsuled extracts in an in vitro GI system. Leaves of Flourensia spp. were collected in wild sites of Coahuila State, and the ethanol extracts were obtained by the Soxhlet method. The encapsulation was performed by the gelation technique, using alginate. The microcapsules formed were characterized in terms of total phenol content (Folin-Ciocalteu method), antioxidant activity by the 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis (3-ethylbenzthiazoline-6-sulphonic) diammonium acid (ABTS), and the ferric reducing antioxidant power (FRAP) assays, scanning electron microscopy (SEM), and thermal analysis, and in vitro GI digestion. The microcapsules were found to have spherical-shape and a micro-scale dimension in the range of 2.168.8??m. Also, the built of microcapsules was confirmed by the appearance of an exothermic peak centered at 600?°C in the DSC analysis. F. microphylla noted for its strong antioxidant activity, even in its encapsulated form. In the gastric system the extracts of fresh microcapsules were released from 7.7% to 14.5%, while values of 26.5% to 53.3% were observed for those dried. For the intestinal system, the higher release was observed for dried microcapsules (59.9% to 78.4%) than for those fresh (26.3% to 30.2%). Thus, it was demonstrated that the alginate microcapsule protected the extracts until they were delivered to the target site in the GI model, and this effect was better with the dried microcapsules of Flourensia spp. This study would set the guide for the application of Flourensia spp. extracts in order to take advantage of their benefits to human health.Author G.N. Puente Romero thanks Mexican Science and Technology Council (CONACYT, Mexico) for MSc fellowship support. Authors would like to thank to María Guadalupe Moreno Esquivel, Edith E. Chaires Colunga, Olga L. Solís Hernández, and M. Leticia Rodríguez González of the Phytochemistry Laboratory from Universidad Autónoma Agraria Antonio Narro, for their support in the lab experiments.info:eu-repo/semantics/publishedVersio

Efecto del tratamiento preoperatorio con estatinas sobre los resultados de la cirugía coronaria

IntroducciónEl uso de estatinas se asocia a una reducción de accidentes coronarios en prevención primaria y secundaria y después de angioplastia primaria.ObjetivoInvestigar si el empleo de estatinas en pacientes sometidos a cirugía de revascularización coronaria (CRC) se asocia a beneficio clínico.MétodosSe incluyeron 102 pacientes consecutivos con enfermedad coronaria para CRC electiva y aislada. En el momento de la inclusión se registró el tratamiento preoperatorio y las variables clínicas basales. En el seguimiento se registró la aparición de muerte de origen cardíaco e infarto agudo de miocardio (IAM) en los primeros 30 días.ResultadosRecibían estatinas 61 pacientes (60%) frente a 41 (40%) que no las recibían. No se encontraron diferencias significativas entre ambas poblaciones respecto a las características basales. A los 30 días se produjo una muerte cardíaca (1,6%) en el grupo que recibió estatinas, frente a cinco (12,2%) en el grupo que no las recibían (p=0,02), el IAM ocurrió en cuatro (6,6%) frente a 8 (19,5%) (p=0,04) y el resultado compuesto de muerte cardíaca o IAM ocurrió en cinco (8,2%) frente a 10 (24,4%) (p=0,02). En un modelo multivariado, el tratamiento preoperatorio con estatinas se mantuvo como un factor independiente de predicción (p=0,01; odds ratio [OR]: 3,6) de la aparición de muerte de causa cardíaca o IAM durante los primeros 30 días después de la intervención.ConclusiónEl tratamiento previo con estatinas se asocia de forma significativa e independiente a un menor riesgo de IAM o muerte de origen cardíaco en pacientes sometidos a CRC.IntroductionStatin treatment diminishes adverse cardiac events both in primary and secondary prevention and also after percutaneous coronary intervention.ObjectiveTo study if preoperative statin treatment is associated with any clinical advantage after coronary artery surgery.MethodsWe enrolled 102 consecutive patients with coronary artery disease, scheduled for elective coronary artery surgery. Combined procedures were excluded. Preoperative treatment and the clinical baseline characteristics were recorded in all patients at inclusion. Cardiac death and acute myocardial infarction (AMI) were recorded during the first 30 days.ResultsSixty one patients (60%) were on preoperative statin treatment vs. 41 (40%) who were not. There were no differences at baseline level between both groups. There was one cardiac death at 30 days (1.6%) in the statin-treatment group vs. five deaths (12.2%) in the nostatin group (p=0.02). Acute myocardial infarction presented in four (6.6%) vs. eight (19.5%) (p=0.04). The primary combined cardiac endpoint made of cardiac death or AMI occurred in five (8.2%) vs. 10 (24.4%) (p=0.02). In a multivariate model, preoperative statin treatment remained an independent predictor (p=0.01; odds ratio [OR] 3.6) of cardiac death or AMI during the first 30 days after surgery.ConclusionPreoperative statin-treatment was significative and independently associated with less risk of AMI or cardiath death in patients who underwent coronary artery bypass grafting

Exhaled volatilome analysis as a useful tool to discriminate asthma with other coexisting atopic diseases in women of childbearing age

©2021. The authors. This document is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by /4.0/ This document is published version of a Published Work that appeared in final form in Scientifc Reports. To access the final edited and published work see https://doi.org/10.1038/s41598-021-92933-2The prevalence of asthma is considerably high among women of childbearing age. Most asthmatic women also often have other atopic disorders. Therefore, the diferentiation between patients with atopic diseases without asthma and asthmatics with coexisting diseases is essential to avoid underdiagnosis of asthma and to design strategies to reduce symptom severity and improve quality of life of patients. Hence, we aimed for the frst time to conduct an analysis of volatile organic compounds in exhaled breath of women of childbearing age as a new approach to discriminate between asthmatics with other coexisting atopic diseases and non-asthmatics (with or without atopic diseases), which could be a helpful tool for more accurate asthma detection and monitoring using a noninvasive technique in the near future. In this study, exhaled air samples of 336 women (training set (n= 211) and validation set (n= 125)) were collected and analyzed by thermal desorption coupled with gas chromatography-mass spectrometry. ASCA (ANOVA (analysis of variance) simultaneous component analysis) and LASSO+LS (least absolute shrinkage and selection operator+ logistic regression) were employed for data analysis. Fifteen statistically signifcant models (p-value< 0.05 in permutation tests) that discriminated asthma with other coexisting atopic diseases in women of childbearing age were generated. Acetone, 2-ethyl-1-hexanol and a tetrahydroisoquinoline derivative were selected as discriminants of asthma with other coexisting atopic diseases. In addition, carbon disulfde, a tetrahydroisoquinoline derivative, 2-ethyl-1-hexanol and decane discriminated asthma disease among patients with other atopic disorders. Results of this study indicate that refned metabolomic analysis of exhaled breath allows asthma with other coexisting atopic diseases discrimination in women of reproductive ag

Fungal and ciliate protozoa are the main rumen microbes associated with methane emissions in dairy cattle

14 Pág. Departamento de Mejora Genetica AnimalMitigating the effects of global warming has become the main challenge for humanity in recent decades. Livestock farming contributes to greenhouse gas emissions, with an important output of methane from enteric fermentation processes, mostly in ruminants. Because ruminal microbiota is directly involved in digestive fermentation processes and methane biosynthesis, understanding the ecological relationships between rumen microorganisms and their active metabolic pathways is essential for reducing emissions. This study analysed whole rumen metagenome using long reads and considering its compositional nature in order to disentangle the role of rumen microbes in methane emissions.This research was financed by RTA2015-00022-C03-02 (METALGEN) project from the National Plan of Research, Development and Innovation 2013–2020 and the Department of Economic Development and Competitiveness (Madrid, Spain). A.L.G. was funded by FPI-INIA grant with reference FPI-SGIT2016-06.Peer reviewe

CB19 223. Experiencia inicial con el implante de prótesis aórticas vía transfemoral

Introducción y objetivosDesde 2006 se dispone de la vía de implante percutánea para las prótesis valvulares aórticas. Por el momento esta vía percutánea se ha reservado para pacientes de alto riesgo con la cirugía con circulación extracorpórea (CEC). Presentamos la experiencia inicial en nuestro hospital con prótesis aórtica percutánea vía transfemoral.Pacientes y métodosSe intervinieron 33 pacientes (60% mujeres; 81,6±4,4años de edad media) entre junio de 2008 y febrero de 2010. EuroSCORE logístico medio de 21%±12,5; EuroSCORE aditivo 9±2,3; seguimiento medio de 7 meses (1-20). Se implantaron 20 prótesis n.° 23 (60%) y 12 n.° 26 (40%).ResultadosDurante la hospitalización fallecieron tres pacientes (9%). En un paciente no se logró colocar la prótesis (3%). Las complicaciones más frecuentes fueron las vasculares en 10 pacientes (30%), seguidas de la insuficiencia cardíaca en cuatro pacientes (12%) y de la necesidad de implantar un marcapasos en otros dos (6%). Fueron transfundidos 16 pacientes (47%). Estancia en cuidados intensivos 1,8±2,3días, y en hospital 10,8±9,7días. En el seguimiento fallecieron tres pacientes (10%), y seis pacientes (21%) reingresaron en el hospital por causa cardíaca. El ecocardiograma postoperatorio mostró insuficiencia aórtica grado II en cuatro pacientes (14%).ConclusionesLa vía transfemoral permite tratar a pacientes de alto riesgo quirúrgico para el uso de CEC, sin embargo no está exenta de riesgos importantes. Mayor experiencia y seguimiento permitirán conocer los pacientes que más se beneficien de este abordaje

MAFG is a potential therapeutic target to restore chemosensitivity in cisplatin-resistant cancer cells by increasing reactive oxygen species

Adjuvant chemotherapy for solid tumors based on platinum-derived compounds such as cisplatin is the treatment of choice in most cases. Cisplatin triggers signaling pathways that lead to cell death, but it also induces changes in tumor cells that modify the therapeutic response, thereby leading to cisplatin resistance. We have recently reported that microRNA-7 is silenced by DNA methylation and is involved in the resistance to platinum in cancer cells through the action of the musculoaponeurotic fibrosarcoma oncogene family, protein G (MAFG). In the present study, we first confirm the miR-7 epigenetic regulation of MAFG in 44 normal- and/or tumor-paired samples in non–small-cell lung cancer (NSCLC). We also provide translational evidence of the role of MAFG and the clinical outcome in NSCLC by the interrogation of two extensive in silico databases of 2019 patients. Moreover, we propose that MAFG-mediated resistance could be conferred due to lower reactive oxygen species production after cisplatin exposure. We developed specifically selected aptamers against MAFG, with high sensitivity to detect the protein at a nuclear level probed by aptacytochemistry and histochemistry analyses. The inhibition of MAFG activity through the action of the specific aptamer apMAFG6F increased the levels of reactive oxygen species production and the sensitivity to cisplatin. We report first the specific nuclear identification of MAFG as a novel detection method for diagnosis in NSCLC, and then we report that MAFG modulates the redox response and confers cell protection against free radicals generated after platinum administration, thus also being a promising therapeutic target.This study was supported by the “Fondo de Investigación Sanitaria-Instituto de Salud Carlos III” [PI15/00186 and CP 08/000689 to I.I.C. ] ; and the European Regional Development Fund/European Social Fund FIS [FEDER/FSE, Una Manera de Hacer Europa] . MINECO funds support O.V., C.R.A. and O.P.contracts through RTC-2015-4362-1 and RTC-2016-5314-1 projects