Estimation of Impulse Wave Run-up Caused by Underwater Landslide in Dam Reservoirs

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

Equivalent Circuit Modeling of the Dielectric Loaded Microwave Biosensor

This article describes the modeling of biological tissues at microwave frequency using equivalent lumped elements. A microwave biosensor based on microstrip ring resonator (MRR), that has been utilized previously for meat quality evaluation is used for this purpose. For the first time, the ring-resonator loaded with the lossy and high permittivity dielectric material, such as; biological tissue, in a partial overlay configuration is analyzed. The equivalent circuit modeling of the structure is then performed to identify the effect of overlay thickness on the resonance frequency. Finally, the relationship of an overlay thickness with the corresponding RC values of the meat equivalent circuit is established. Simulated, calculated and measured results are then compared for validation. Results are well agreed while the observed discrepancy is in acceptable limit

RF MEMS Based Tunable Bowtie Shaped Substrate Integrated Waveguide Filter

A tunable bandpass filter based on a technique that utilizes substrate integrated waveguide (SIW) and double coupling is presented. The SIW based bandpass filter is implemented using a bowtie shaped resonator structure. The bowtie shaped filter exhibits similar performance as found in rectangular and circular shaped SIW based bandpass filters. This concept reduces the circuit foot print of SIW; along with miniaturization high quality factor is maintained by the structure. The design methodology for single-pole triangular resonator structure is presented. Two different inter-resonator couplings of the resonators are incorporated in the design of the two-pole bowtie shaped SIW bandpass filter, and switching between the two couplings using a packaged RF MEMS switch delivers the tunable filter. A tunning of 1 GHz is achieved for two frequency states of 6.3 and 7.3 GHz. The total size of the circuit is 70mm x 36mm x 0.787 mm (LxWxH)

The clinical pattern of HER-2/neu oncogene overexpressing breast cancer in Pakistani patients at initial presentation: an analysis of HER-2/neu positive versus negative disease--a preliminary report

Background: HER 2/new oncogene is an important prognostic marker in Breast Cancer and has implications in therapy planning.Objective: To describe the clinical features of HER 2/new positive and negative Breast Cancer in the Pakistani patient population and note clinical differences between the two groups if any.Design: A retrospective analysis of Breast Cancer cases at the Aga Khan University, Hospital.METHOD: Immunochemical staining on formation fixed paraffin embedded tissue using oxidase antiperoxidase method. A total of 152 Breast cancer tissue samples were tested for HER-2/neu gene presence. Of these 43 (39%) samples tested positive and 109 (61%) tested negative. A comparison of the two groups revealed that only a few factors tested for either significance or borderline statistical significance between the two groups. These factors included the estrogen receptor status and the number of lymph nodes involved in the axilla. The progesterone receptor status was of borderline significance.CONCLUSION: Given the large number of factors tested it appears that there is no consistent defining feature which helps to separate HER-2/neu positive versus HER-2/neu negative cases with Breast Cancer

Study protocol for a multicentre longitudinal mixed methods study to explore the Outcomes of ChildrEn and fAmilies in the first year after paediatric Intensive Care: the OCEANIC study.

INTRODUCTION: Annually in the UK, 20 000 children become very ill or injured and need specialist care within a paediatric intensive care unit (PICU). Most children survive. However, some children and their families may experience problems after they have left the PICU including physical, functional and/or emotional problems. It is unknown which children and families experience such problems, when these occur or what causes them. The aim of this mixed-method longitudinal cohort study is to understand the physical, functional, emotional and social impact of children surviving PICU (aged: 1 month-17 years), their parents and siblings, during the first year after a PICU admission. METHODS AND ANALYSIS: A quantitative study involving 300 child survivors of PICU; 300 parents; and 150-300 siblings will collect data (using self-completion questionnaires) at baseline, PICU discharge, 1, 3, 6 and 12 months post-PICU discharge. Questionnaires will comprise validated and reliable instruments. Demographic data, PICU admission and treatment data, health-related quality of life, functional status, strengths and difficulties behaviour and post-traumatic stress symptoms will be collected from the child. Parent and sibling data will be collected on the impact of paediatric health conditions on the family's functioning capabilities, levels of anxiety and social impact of the child's PICU admission. Data will be analysed using descriptive and inferential statistics. Concurrently, an embedded qualitative study involving semistructured interviews with 24 enrolled families at 3 months and 9 months post-PICU discharge will be undertaken. Framework analysis will be used to analyse the qualitative data. ETHICS AND DISSEMINATION: The study has received ethical approval from the National Health Services Research Ethics Committee (Ref: 19/WM/0290) and full governance clearance. This will be the first UK study to comprehensively investigate physical, functional, emotional and social consequences of PICU survival in the first-year postdischarge.Clinical Trials Registration Number: ISRCTN28072812 [Pre-results]

Impedance-Based Water-Quality Monitoring Using the Parallel-Plate Method

The application of electromagnetic (EM) waves to measure the electrical properties (dielectric constant and loss tangent) of materials is a well-known approach. The electrical properties can be used to indirectly measure several physical properties of solutions in water such as the concentration and chemical composition of contaminants in water, as a representative of the liquid phase in soil. A capacitive method of measuring dielectric properties of solutions is proposed to detect and determine low-concentration chemical and biological contaminations in water. The primary objective of this project is to design a low-cost sensor that would require small volumes of samples to detect low concentrations of dissolved contaminants in water. A forward model was developed using a finite-element method (FEM) to simulate the experimental setup (EXP). A calibration function was also developed to minimize deviations between FEM and EXP results for benchmark/reference solutions with known dielectric properties. The validated, calibrated forward model was then inverted to calculate the electrical properties of unknown solutions using the corresponding EXP results

Relative validity of a food and beverage preference questionnaire to characterize taste phenotypes in children adolescents and adults

To assess the relative validity of our food and beverage preference questionnaire we investigated the association between sweet and fatty taste preference scores (assessed using a food and beverage preference questionnaire) and sweet and fatty food propensity scores (derived from a food frequency questionnaire). In I.Family, a large European multi-country cohort study, 12, 207 participants from Cyprus, Estonia, Germany, Hungary, Italy, Spain and Sweden, including 5291 adults, 3082 adolescents, and 3834 children, completed a food and beverage preference questionnaire with 63 items. Cumulative preference scores for sweet and fatty taste were calculated from the single item ranking ranging from 1 to 5. The relative consumption frequency of foods classified as sweet and fatty was used to calculate the corresponding consumption propensities, a continuous variable ranging from 0 to 100. We conducted regression analyses to investigate the association between sweet and fatty taste preference scores and sweet and fatty food propensity scores, respectively, separately for adults, adolescents =12 years, and for children <12 years. The overall sweet taste preference score was positively associated with the sweet food consumption propensity score (ß = 2.4, 95% CI: 2.1;2.7) and the fatty taste preference score was positively associated with the fatty food consumption propensity score (ß = 2.0, 95% CI: 1.8;2.2). After stratification for age (children <12 years, adolescents =12 years, and adults), the effect remained significant in all age groups and was strongest in adolescents and adults. We conclude that our food and beverage preference questionnaire is a useful instrument for epidemiological studies on sensory perception and health outcomes and for the characterization of sensory taste phenotypes