Exploring modality switching effects in negated sentences: further evidence for grounded representations

Theories of embodied cognition (e.g., Perceptual Symbol Systems Theory; Barsalou, 1999, 2009) suggest that modality specific simulations underlie the representation of concepts. Supporting evidence comes from modality switch costs: participants are slower to verify a property in one modality (e.g., auditory, BLENDER-loud) after verifying a property in a different modality (e.g., gustatory, CRANBERRIES-tart) compared to the same modality (e.g., LEAVES-rustling, Pecher et al., 2003). Similarly, modality switching costs lead to a modulation of the N400 effect in event-related potentials (ERPs; Collins et al., 2011; Hald et al., 2011). This effect of modality switching has also been shown to interact with the veracity of the sentence (Hald et al., 2011). The current ERP study further explores the role of modality match/mismatch on the processing of veracity as well as negation (sentences containing “not”). Our results indicate a modulation in the ERP based on modality and veracity, plus an interaction. The evidence supports the idea that modality specific simulations occur during language processing, and furthermore suggest that these simulations alter the processing of negation

NOViSE: a virtual natural orifice transluminal endoscopic surgery simulator

Purpose: Natural Orifice Transluminal Endoscopic Surgery (NOTES) is a novel technique in minimally invasive surgery whereby a flexible endoscope is inserted via a natural orifice to gain access to the abdominal cavity, leaving no external scars. This innovative use of flexible endoscopy creates many new challenges and is associated with a steep learning curve for clinicians. Methods: We developed NOViSE - the first force-feedback enabled virtual reality simulator for NOTES training supporting a flexible endoscope. The haptic device is custom built and the behaviour of the virtual flexible endoscope is based on an established theoretical framework – the Cosserat Theory of Elastic Rods. Results: We present the application of NOViSE to the simulation of a hybrid trans-gastric cholecystectomy procedure. Preliminary results of face, content and construct validation have previously shown that NOViSE delivers the required level of realism for training of endoscopic manipulation skills specific to NOTES Conclusions: VR simulation of NOTES procedures can contribute to surgical training and improve the educational experience without putting patients at risk, raising ethical issues or requiring expensive animal or cadaver facilities. In the context of an experimental technique, NOViSE could potentially facilitate NOTES development and contribute to its wider use by keeping practitioners up to date with this novel surgical technique. NOViSE is a first prototype and the initial results indicate that it provides promising foundations for further development

Switching modalities in a sentence verification task: ERP evidence for embodied language processing

In an event related potential (ERP) experiment using written language materials only, we investigated a potential modulation of the N400 by the modality switch effect. The modality switch effect occurs when a first sentence, describing a fact grounded in one modality, is followed by a second sentence describing a second fact grounded in a different modality. For example, "A cellar is dark" (visual), was preceded by either another visual property "Ham is pink" or by a tactile property "A mitten is soft." We also investigated whether the modality switch effect occurs for false sentences ("A cellar is light"). We found that, for true sentences, the ERP at the critical word "dark" elicited a significantly greater frontal, early N400-like effect (270370 ms) when there was a modality mismatch than when there was a modality-match. This pattern was not found for the critical word "light" in false sentences. Results similar to the frontal negativity were obtained in a late time window (500700 ms). The obtained ERP effect is similar to one previously obtained for pictures. We conclude that in this paradigm we obtained fast access to conceptual properties for modality-matched pairs, which leads to embodiment effects similar to those previously obtained with pictorial stimuli

Improving the entanglement transfer from continuous variable systems to localized qubits using non Gaussian states

We investigate the entanglement transfer from a bipartite continuous-variable (CV) system to a pair of localized qubits assuming that each CV mode couples to one qubit via the off-resonance Jaynes-Cummings interaction with different interaction times for the two subsystems. First, we consider the case of the CV system prepared in a Bell-like superposition and investigate the conditions for maximum entanglement transfer. Then we analyze the general case of two-mode CV states that can be represented by a Schmidt decomposition in the Fock number basis. This class includes both Gaussian and non Gaussian CV states, as for example twin-beam (TWB) and pair-coherent (TMC, also known as two-mode-coher ent) states respectively. Under resonance conditions, equal interaction times for both qubits and different initial preparations, we find that the entanglement transfer is more efficient for TMC than for TWB states. In the perspective of applications such as in cavity QED or with superconducting qubits, we analyze in details the effects of off-resonance interactions (detuning) and different interaction times for the two qubits, and discuss conditions to preserve the entanglement transfer.Comment: revised version, 11 pages, 7 figures (few of them low-res

An ERP study of anaphor resolution with focused and non-focused antecedents

The goal of this study is to better understand when (and why) the combination of semantic overlap between antecedent and anaphor and antecedent focus leads to difficulty in anaphor processing. To investigate these questions, three ERP experiments manipulating semantic overlap and focus compared the ERPs from the onset of the anaphor as well as from the onset of the last word in the sentence containing the anaphor. Our results suggest that although the focus status of an antecedent and the semantic overlap between the antecedent and anaphor are important, these factors are not the only significant contributors to online anaphor resolution. Factors such as readers‘ expectations about thematic shifts also influence the processing. We consider our results in relation to two accounts of anaphor resolution, the Informational Load Hypothesis (Almor, 1999; Almor & Eimas, 2008) and JANUS (Garnham & Cowles, 2008)

Modality switching and negation: ERP evidence for modality-specific simulations during negation processing

The Perceptual Symbol System Theory of cognition (Barsalou, 1999) suggests that modality-specific simulations underlie representation of concepts. This is evidenced by processing costs for switching modalities. That is, participants are slower to verify a property in the auditory modality (e.g., BLENDER-loud) after verifying a property in a different modality (e.g., CRANBERRIES-tart) and faster when verifying a property in the same modality (e.g., LEAVES-rustling). The modality switch cost has also been shown to lead to a modulation of the N400 event-related potential (ERP) (Collins, Pecher, Zeelenberg & Coulson, 2011 using a property verification task; Hald, Marshall, Janssen & Garnham, 2011 using a sentence verification task). In a separate line of research, ERP studies have indicated that without a discourse context, negated sentences are more difficult to process than affirmative sentences, leading to a different N400 pattern for negative sentences than for affirmative sentences (e.g., Fischler, Bloom, Childers, Roucos, & Perry, 1983.) Unlike affirmative sentences, sentences containing negation show a larger N400 for correct, semantically coherent single sentences (i.e., factually true sentences) than for semantically incorrect sentences (i.e., false sentences). However, Nieuwland and Kuperberg (2008,) found that the pragmatics of the sentence can change this N400 pattern to one closer to affirmative sentences. The goal of the current study was to explore whether the processing of negation could be aided by modality matching information. Other evidence suggests that comprehenders create a simulation of negative sentences (Kaup, Yaxley, Madden, Zwaan, & Lüdtke, 2007), but it is unclear whether modality matching information could modulate the processing cost of negation. Essentially, can modality matching information as reported by Collins et al., (2011) and Hald et al., (2011) lead to a modulation of the N400 for true negated sentences similar to that seen when discourse pragmatics supports negation? Furthermore, we were interested in whether the modality switch effect would lead to a similar pattern in the ERPs as that found with affirmative sentences (Collins et al., 2011 & Hald et al., 2011). Using a within-subjects design we used 160 pairs of experimental pairs which were either of the same or of a different modality. All experimental items were either visual or tactile modality and were drawn from existing sets of materials (Pecher, et al., 2003; Van Dantzig, et al., 2008). For example, a different modality pair was “A light bulb is very hot” followed by “Rice isn’t black” versus a same visual modality pair “A giraffe is spotted” followed by “Rice isn’t black”. We predicted that the underlined word is where a modulation in the N400 may be seen. Additionally, we explored veracity by making half of the experimental target sentences false (“Rice isn’t white”). Participants were asked to judge whether each sentence was typically true or false. Our initial results indicate a modulation in the ERP based on both modality and veracity. For true (“Rice isn’t black”) and false target statements (“Rice isn’t white”) different modality pairs elicit a larger frontal-central N400 like effect compared to same modality pairs (Figure 1), replicating Hald et al., (2011). When comparing true versus false, the different modality pairs elicit a large posterior N400 for true compared to false sentences (replicating the effect for negated sentences, i.e., Fischler et al., 1983). However for same modality pairs there is a reduction in the N400 to true statements; no difference is seen between true and false statements in the ERP (Figure 2). These results replicate and extend previous ERP findings using the modality switch paradigm. The evidence suggests that not only do modality-specific simulations occur but they can even aid the processing of negation

A farm transmission model for Salmonella in pigs for individual EU Member States

The burden of Salmonella entering pig slaughterhouses across the European Union (EU) is considered to be of public health significance. Therefore, targets will be set for each EU Member State (MS) to reduce the prevalence of Salmonella in pigs at slaughter. As part of the evidence base for the development of National Control Plans (NCPs), a Quantitative Microbiological Risk Assessment (QMRA) was funded to support the scientific opinion required by the EC from the European Food Safety Authority, and subsequently adopted by the BIOHAZ panel