Clinical effects of goshajinkigan for male infertility

本剤は八味地黄丸にゴシツ, シャゼンシを加味した漢方薬である.その粉末5.0 g/日を男性不妊症患者中, 無力精子症3例, 乏精子症27例の計30症例に3ヵ月以上投与し, 検討した.1)精子運動率に対して53%の症例に有効性を認めた.2)精子数は33%に有効な増加を認め, ことに精子濃度10×106/ml以上の症例に有効であった.3)妊娠成立は30例中1症例のみであった.4)血清LH, FSH, 及び精液中prostaglandin E値には本剤投与前後において有意の変動は認められなかったNo study has been reported of the effects of Goshajinkigan on male infertility. Thirty infertile male patients were orally given Goshajinkigan at a daily dose of 5.0 g for three months or more. Sixteen of these patients showed significant improvement in sperm motility. Ten cases showed effective increase in sperm count. Only one patients became pregnant during the period of administration of this drug. Laboratory examination showed no significant change in serum LH, serum FSH or prostaglandin E in seminal fluid. These results suggest that administration of TSUMURA-Goshajinkigan is effective as therapy for male infertility, but how this drug may be involved in promoting fertility should be investigated in future

Two cases of nonfunctioning adrenocortical adenoma

Two cases of benign nonfunctioning adrenocortical adenoma found incidentally by computerized tomography (CT)scan are presented. One patient had some abnormal values in subsequent endocrine studies, but did not have any recognizable clinical syndromes. The adenomas were removed surgically

Pneumocystis carinii pneumonia in renal transplant recipients treated with cyclosporin

Four cases of pneumocystis carinii pneumonia occurred among 38 renal transplant recipients. Diagnosis was confirmed by cyst concentration technique in 2 cases. The other 2 cases were clinically, from the rapid improvement of fever, pulmonary infiltrates and hypoxia following a therapeutic trial of high dose sulfamethoxazole-trimethoprim. All patients responded to treatment with high dose sulfamethoxazole-trimethoprim. Three patients survived pneumocystis carinii pneumonia, but i died due to aspergillosis. One patients showed serological evidence of concomitant cytomegalovirus infection

骨梁の画像解析における数理形態フィルタの適用性の検討

骨粗鬆症の診断,予防,そして治療の導入には骨強度の計測が重要である.現在,骨強度の推定法のひとつとして,骨X線写真に写る骨梁像から画像処理による骨梁の構造解析を行い,骨梁の特徴量を求める手法が,種々試みられている.今回我々は,骨梁の特徴量として,骨梁の太さ,長さ,骨梁の面積,骨梁の本数を求める構造解析において,画像処理の過程で,画像の雑音を除去して図形パターンの特徴を2値化画像として抽出する数理形態フィルタの適用が有効であるか否かについて検討した.その結果,骨梁の2次元画像解析では,数理形態フィルタを適用することによって,雑音が除去され,骨梁の特徴が強調された画像を得ることが可能であった.また,特に骨梁の太さの解析では,Opening処理を行うことによって,踵骨骨密度との相関関係が改善されることがわかった