Research on the Government Decision Support System Based on Modeling and Simulation

随着网络信息技术的发展，随着大数据时代的到来，政府在做公共决策时将面对海量数据和复杂系统，决策难度将直线上升。为了提高政府的行政能力、管理水平和决策准确性，将决策支持系统及建模仿真等新技术引入政府成为必然趋势。基于建模仿真的政府决策支持系统，可以利用电子政务综合数据仓库中存储的大量数据，考虑决策者的偏好需要，并且充分把握决策问题的特点性质，从而使仿真模型更加真实、仿真结果更符合实际情况，通过模拟预演和不断优化来提高政策制定的科学性和可行性。 本文分为五大部分：第一是绪论部分，主要对研究的背景和意义进行论述，并梳理了相关研究文献，明确了研究的思路和方法；第二是政府决策支持系统的研究进程与发展，...With the development of information technology and the arrival of big data era, government will make public policy decisions in the face of massive data and complex causal, so the difficulty of making decisions will shoot up. In order to improve the government's ability, management and decision-making accuracy, Decision Support Systems and Modeling and Simulation, and other new technologies will b...学位：管理学硕士院系专业：公共事务学院_行政管理学号：1392013115030

利用快速傅里叶变换算法仿真光学相关器

光学相关器在图像模式识别中具有广泛的应用,包括匹配滤波相关器和联合变换相关器,两种相关器在应用中各有优势。文章通过利用数学软件MATlAb的快速傅里叶变换算法编程仿真两种光学相关器,得到实验结果的二维图像和三维图像,并比较两种相关器的识别效果

Research on the rapid inactivation of typical algae blooms by hydroxyl radical

以典型水华藻铜绿微囊藻、针杆藻和四尾栅藻为研究对象,利用大气压强电离放电高效生成的羟基自由基(·OH)对3种藻进行杀灭.采用荧光染色、流式细胞仪; 和光合活性等生物学方法,确定·OH杀灭的阈值浓度和时间,并观察细胞形态变化.结果表明,当混合藻中铜绿微囊藻、针杆藻和四尾栅藻的初始藻密度分别为1; 9.5*10~4、21.8*10~4和4.90*10~4cells/mL时,; ·OH杀灭的阈值浓度为1.07mg/L,致死时间为4.5s;形态观察结果表明,处理后各种藻的形态是完整的,无内溶质溢出.因此,采用·OH可实现高; 效快速杀灭水华藻,有效保障饮用水安全.Algae blooming in water sources breaks out increasingly and seriously; threatened the water supply safety. Bench scale tests were conducted to; study the effects of ·OH generated from strong ionization discharge and; high pressure water jet cavitation on cell density, cell integrity and; photosynthetic capacity of 3kinds of typical freshwater algae. Algae; species including Microcystis aeruginosa, Synedra sp., and Scenedesmus; quadricuauda were respectively prepared at concentrations of 19.5*10~4,; 21.8*10~4 and 4.90*10~4 cells/mL, and the cell integrity was assessed by; flow cytometry. Results suggested that the ·OH lethal threshold of the; algae was 1.07mg/L within the exposure time of 4.5s. The cell; morphological observation results showed that all the cells were; integral and no cytoplasm composition spilled. Hence, large-scale; production of ·OH is a novel method to inactive typical algae species; efficiently and to protect drinking water safety simultaneously.国家科技支撑计划资助项目; 国家重大科研仪器研制项

Prader-Willi综合征分子分型诊断方法的初步研究

【目的】探讨Prader—Willi综合征（PWS）的短串联重复序列（STR）连锁分析诊断方法，为遗传咨询提供相关信息。【方法】对一例临床疑似病例经甲基化特异性PCR（MS—PCR）确诊为PWS后．应用15号染色体特定区域的STR进行家系连锁分析，探讨其在PWS分子缺陷类型诊断方面的可行性。【结果】STR连锁分析结果显示该患者为父源缺失型PWS。【结论】STR连锁分析是一种可准确诊断PWS并明确其分子缺陷类型的好方法：国人相关区域的STR位点及其多态信息等有待进一步研究．以完善并最终建立该方法

富勒烯团簇B_xN_(36-x)的电子结构研究

采用从头算量子化学方法在MP2/3 21G水平对BxN36 x富勒烯团簇进行理论研究.从理论上预测了具有与碳原子簇C36相似结构的一系列BxN36 x富勒烯团簇的存在,并对其几何构型进行优化,研究电子结构,探讨其稳定性.结果表明B15N21比C36具有更好的反应活性

Preparation and Application of Soluble Human Squamous Cell Carcinoma Antigen Expressed by Escherichia coli

旨在建立基于大肠杆菌表达系统的高效可溶性表达人鳞状上皮细胞癌抗原(SCCAg)方法,获得具有较好活性的重组SCCAg抗原并应用于建立抗原检测方法; 。基于pGEX-6P-l载体和大肠杆菌E. coli; ER2566菌株开展重组SCCAg抗原可溶性表达纯化方法研究,评价纯化抗原活性,筛选特异性单克隆抗体,初步建立并评价SCCAg抗原检测方法。结果; 显示,pGEX-6P-l载体和E coli; ER2566菌株可用于建立较高效的可溶性表达和纯化SCCAg抗原的方法,获得了具有较高纯度和活性的重组SCCAg抗原,筛选获得特异性单克隆抗体并; 初步建立了 SCCAg管式化学发光检测方法。建立了有效的基于大肠杆菌表达系统的可溶性表达和纯化SCCAg的方法。The aims of this study are to establish a method for efficient soluble; expression of human squamous cell carcinoma antigen(SCCAg ) based on; Escherichia coli expression system and obtain the recombinant SCCAg; antigen in fine activity, then apply it in the detection method; establishment of antigen. The study on the method of soluble expression; and purification of recombinant SCCAg antigen was conducted based on; pGEX-6P-l vector and E. coli ER2566 strain. The activity of the purified; antigen was evaluated by Abbott Kit and the specific monoclonal antibody; was screened by indirect ELISA. It was proved that PGEX-6P-1 vector and; E. coli strain ER2566 could be used to establish efficient soluble; expression and purification method for recombinant SCCAg antigen.; Moreover, the recombinant SCCAg antigen was proved to be in high purity; and activity. Thus,the SCCAg detection method of chemical luminous tube; was established with the specific monoclonal antibodies. In conclusion,; an effective method for the expression and purification of SCCAg, which; is based on the E. coli expression system, is established.国家高技术研究发展计划(863计划

The Study of Desalination for Disrupted Wall Paintings at Cave 98 of Mogao Grottoes

Disruption means that the soluble salts in the plaster layer of a wall painting changes their form from dissolved to crystallized salts, and vice versa, with the changes of humidity in the surrounding environment. This change of forms creates an impact of swelling and shrinking in the plaster layer. This repeated impact damages the plaster layer and causes it to become loose and leads to deterioration. The only method to treat this deterioration caused by disruption of salts is to apply a combined method of reinforcement and desalination. The subject of this paper is the disruption of the wall paintings at Cave 98 of Mogao grottoes in China, in which synthetic material of high water and salt absorption, known as starch grafted acrylamide, is used as a desalination material applied on tissue of high water absorption to reinforce the disrupted wall paintings, to decrease the salts of the wall paintings, and to decrease the damage caused by the salts. This study tests the performance of desalination material and　assessed the results in two different ways.departmental bulletin pape

Analysis on the characteristics of macrobenthis community in the North-west Daya Bay of South China Bay in spring

利用2008年春季在大亚湾西北部海域开展的12个测站的大型底栖动物调查资料,对该海域大型底栖动物的群落特征进行分析。结果表明该海域内大型底栖动物优势种由粗帝汶蛤(TIMOClEA SCAbrA)、波纹巴非蛤(PAPHIA undulATA)、上野蜾蠃蜚(COrOPHIuM uEnOI)、方背鳞虫(lEPIdOnOTuS SQuAMATuS)、刀明樱蛤(MOErEllA CulTEr)和角海蛹(OPHElIA ACuMInATA)等6种组成;可划分为4个群落,群落Ⅱ和群落Ⅰ为主体群落,群落Ⅲ和群落Ⅳ分布区较小,群落间差异较大。大型底栖动物数量上以个体较大的软体动物占优,但群落的组成则以多毛类和甲壳类为主,其组成情况基本上反映了群落的特征。群落Ⅰ以多毛类-甲壳类为表征,群落Ⅱ则以甲壳类-多毛类-软体动物为表征。栖息环境的差异,是造成群落间差异的主要原因;群落多样性水平呈群落Ⅲ>群落Ⅱ>群落Ⅰ>群落Ⅳ,沉积环境的污染状况和人为扰动是影响多样性水平的主要因素;群落整体的稳定性较好,未受到明显的扰动,但分布于航道区域和渔业生产作业区的群落Ⅳ和群落Ⅲ,在航道建设、疏浚和渔业生产的影响下,群落受到一定程度的扰动,稳定性较弱。Based on the data collected from 12 research stations in the North-west Daya Bay,South China Sea in spring 2008,the characteristics of macrobenthis community were examined.The results showed that the dominant macrobenthic species were Timoclea scabra,Paphia undulate,Corophium uenoi,Lepidonotus squamatus,Moerella culter and Ophelia acuminate.The macrobenthos community could be divided into four groups with notable differences.Group Ⅰ and Ⅱ were the dominant groups,while the distribution areas of Groups Ⅲ and Ⅳ were relatively small.Overall,molluscs was dominant in quantity in the macrobenthos community but the community was mainly composed of Annelida and Arthropoda,reflecting the characteristics of the community.The dominant macrobenthic species of group Ⅰ were Timoclea scabra,Nephtys oligobranchia,Theora lata,Sigambra hanaokai,Glycinde gurjanvae,Prionospio malmgreni,Timoclea scabra,Turritella bacillum,Corophium tridentium,Phyllodocidae und.,Nectoneanthes alatopalpis,Ericthonius pugnax,Pseudopythina sp.and Stylochus ijimai.Species belonging to this group distributed in the nearshore area of Aotou Harbor and Nanhai Petrochemicals Basement Group Ⅱ assemblage includes Paphia undulata,Timoclea scabra,Corophium uenoi,Prionospio malmgreni,Sigambra hanaokai,Ophelia acuminata,Mediomastus sp.,Nephtys oligobranchia,Moerella culter,Corophium lamellatum,Paraprionospio pinnata and Prionospio pulchra.These species distributed mainly around the Chunzhou Island where suspended long line culture of oyster was common.The discriminating species for Group Ⅰ were S.hanaokai,N.soligobranchia,P.malmgreni,N.alatopalpis and E.pugnax while group Ⅱ were C.uenoi,P.malmgreni,S.hanaokai,N.oligobranchia,T.scabra,M.sp.,Phyllodocidae und.,P.pinnata,O.acuminata,C.lamellatum,M.culter and Chaetozone sp.Group Ⅲ assemblage were mainly found in the west side of Mabianzhou,where it was a fishing ground for Arthropoda in Daya Bay.Group Ⅳ was distributed in area where main shipping routes passed through,in the east side of area of Group Ⅱ and in between the area of Group Ⅰ and Ⅲ.For each community group,while group Ⅱ Group Ⅰ was dominated by Annelida and Arthropoda while Group Ⅱ was dominated by arthropoda,annelida and mollusca;such difference is mainly because of the difference in habitat conditions.Diversity of macrobentho community was highest in Group Ⅲ,followed by Group Ⅱ,Group Ⅰ and then Group Ⅳ.Poor habitat condition caused by pollution,sedimentation and other human disturbances were the main reasons for the differences in diversity between groups.In general,macrobenthos community in the North-west Daya Bay of South China Sea was stable in spring.However,community structure of Groups Ⅳ and Ⅲ,which distributed in the main navigation route and fishing grounds,were less stable;suggesting the disturbances from maintenance of navigation channel and fishing activities might have reduced community stability.中央级公益性科研院所基本科研业务费专项基金(2007ZD08;2007TS08;2010YD10

Evaluation of chemiluminescence immunoassays kits for detection of influenza A virus

目的考核甲型流感化学发光检测试剂的灵敏度和特异性。方法分别利用病毒分离培养液和入境人群的鼻咽拭子标本考查甲型流感试剂盒的检测灵敏度和特异性。结果化学发光法对H1、H3、H5、H7、H9等亚型的甲型流感病毒株均有很好的检出率,灵敏度明显优于flu A-dOT和dIrECTIgEn Ez flu A;对102份入境人群鼻咽拭子标本的检测灵敏度为97.62%。结论甲型流感化学发光检测试剂具有很好的灵敏度和特异性,适用于口岸现场的甲型流感快速筛查。Objective To evaluate the sensitivity and specificity of chemiluminescence immunoassays kit for detection of influenza A virus.Methods To analyze the sensitivity and specificity of three different assay kits for detection of influenza A virus by using the viral culture liquid and nasopharyngeal swabs from entry-exit travelers.Results The chemiluminescence immunoassays kit had a good detection rate when it was tested against a panel of influenza A virus strains(H1/H3/H5/H7/H9),and its sensitivity was much better than Flu A-DOT kit`s and Directigen EZ Flu A kit' chemiluminescence immunoassays kit used for the detection of 102 nasopharyngeal swabs from entryexit travelers had a detection sensitivity of 97.62%.Conclusion Chemiluminescence immunoassays kit had good sensitivity and specificity, which was fit for the rapid detection of influenza A virus at frontier ports.国家质检总局科技计划项目(2014IK045); 厦门市科技惠民项目(3502Z20144083

低龄DDH患儿初次开放复位术中股骨截骨必要性的前瞻性随机对照试验研究方案

回顾性研究发现,股骨截骨术并非低龄DDH患儿手术治疗所必须的,而应根据患儿具体情况合理选择;本研究通过多中心前瞻性研究进一步探讨对于18个月至3岁DDH患儿是否要行股骨截骨术。FSODDH项目为一项多中心前瞻性随机对照临床试验研究。研究设计拟招募200名单侧低龄DDH患儿,随机分成股骨截骨组(n=100)和股骨不截骨组(n=100)。股骨截骨组患儿全部采取髋关节开放复位术、骨盆截骨术及股骨截骨术治疗;股骨不截骨组患儿全部采取髋关节开放复位术及骨盆截骨术治疗;术后定期随访至少2年。收集术前、术后1周、术后1个月、术后3个月、术后6个月、术后1年及术后2年的髋关节正位X线影像资料,比较两组患儿的髋臼指数、股骨头坏死率、再脱位率、术中出血量、手术时间和住院天数等临床指标。这一多中心前瞻性研究将能为低龄DDH患儿是否需行股骨截骨术提供循证医学证据