Research and Application of Computer Generated Hologram on Digital Watermarking

随着多媒体技术和网络技术的发展，数字多媒体产品的版权保护和安全问题成为一个相当重要而又富有挑战性的研究课题。作为一种数字产品版权保护的有效解决方案，数字水印技术被广泛地研究。由于全息图具有天然的加密特性以及很强的抗干扰能力，全息技术被引入到数字水印领域，为保护数字产品提供新的有效途径。本文对计算全息图在数字图像水印技术中的应用进行了深入的研究，主要研究内容和成果如下： 1) 提出用一个聚类中心迭代选择过程来代替聚类中心随机初始化过程，对FCM(FuzzyC-Means)聚类算法进行改进。在此基础上，提出一种自适应计算全息图像水印算法。结合人眼视觉掩蔽特性，该水印算法首先利用改进的FCM算法在...With the great development of multimedia and internet techniques, the copyright protection and security of digital media become an important and challenging research topic. Digital watermarking which is regarded as an efficient approach for the protection of digital data has been widely explored. Recently, a new approach which uses digital holograms as the watermarks has been introduced because of...学位：理学博士院系专业：物理与机电工程学院物理学系_光学学号：1982008015051

互联网金融的发展逻辑——基于金融与互联网功能耦合的视角

作为新常态调整下发展起来的全新的金融业态,互联网金融给以商业银行为代表的传统金融体系带来了不小的冲击,这是金融发展意料之外也是结构调整下情理之中的结果。如何把握互联网金融的发展逻辑,破解存在的掣肘,进而引领其健康发展？本文从互联网金融的内涵与表现形式入手,运用相关金融基础理论,以金融与互联网功能耦合的视角为切入点,力图从整体角度把握其发展逻辑,并提出互联网金融发展的立体框架展望。教育部人文社会科学研究青年基金项目“中国式分权下的地方政府质量提升路径研究”(12CJL022)阶段性成

日本企業の新興国市場開拓における組織学習の効果と影響要因に関する研究：在タイ日系企業のアンケート調査に基づいて

　本研究の主たる目的は，タイに進出している日系企業へのアンケート調査に基づいて，日本企業の新興国市場開拓における組織学習，とりわけ探索的学習がもたらす効果及びその影響要因を明らかにすることである．在タイ日系企業56社から得られた調査結果に対する統計分析により以下のような結論が得られた．探索的学習の取り組み度合いは活用的学習よりかなり低いが，新興国現地経営資源獲得の目標達成にポジティブな影響をもたらすことが明らかにされた．一方で，活用的学習は新興国現地経営資源獲得の目標達成にネガティブな影響を及ぼしていることも示された．探索的学習を推進するためには，産業技術環境の変化がその緊急性と必要性を高めるが，本社の海外現地への配慮と柔軟な対応及び現地法人における自由闊達な組織風土が重要な要因であることが確認された．これらの結論は日本企業の新興国市場開拓ないし海外事業展開に有益な示唆を与えたといえよう．Based on the questionnaire survey to Japanese invested firms in Thailand, this paper aims to make clear the effect as well as influential factors of organization learning, especially exploratory learning, for Japanese business development in emerging markets. Statistics analysis on the data acquired from 56 Japanese firms in Thailand leads to conclusions as follows. Although exploratory learning was not implemented as much as exploitive learning, it shows positive effect on the achievement in acquiring the local management resources of emerging markets. However, exploitive learning shows negative effect on that achievement. The factors that exhibit significant influences on promoting exploratory learning are changes in industrial technological environment, flexible consideration and responses of headquarters management towards overseas businesses, as well as the open and free organization culture at the Japanese invested firms in Thailand. These conclusions provide valuable suggestions for Japanese companies to develop businesses in emerging markets as well as overseas markets in general

KOH活化法制备煤基活性炭

新疆煤炭资源丰富,约占全国总储量的40%。活性炭是一种优良的吸附剂,原料来源广泛,其中以新疆煤炭为原料制备高性能的煤基活性炭可以增加煤炭的高效利用,提高其经济价值。但由于煤炭的灰分含量普遍较高且组成复杂,以物理活化法制得的煤基活性炭性能较低,因此本文采用kOH为活化剂,研究碱碳比、终温和升温速率对活性炭比表面积和孔结构的影响,最终确定煤基活性炭的最佳制备工艺条件为:碱碳比2:1、活化终温800℃、升温速率5℃/MIn,在此实验条件下制得比表面积为1560 M2g-1,孔容为0.622CM3g-1的煤基活性炭

STUDY ON THE ANTIFUNGAL ACTIVITIES OF ENDOPHYTIC FUNGI ISOLATED FROM SEVERAL PHARMACEUTICAL PLANTS

从三尖杉 ,南方红豆杉及香榧中分离出 1 72株内生真菌 ,对其进行抗菌活性检测 ,结果表明共 90株内生真菌对一种或多种植物病原真菌 ,如红色面孢霉 (Neurosporasp .) ,木霉 (Trichodermasp .) ,镰刀菌 (Fusariumsp .)等有抑制作用 ,来自三尖杉、南方红豆杉和香榧的抗菌活性菌株比例分别为 40 %,5 4 2 %及 5 7 1 %。其中平板抑菌圈直径大于1 5mm的高抗菌株有 3 5株。按Ainsworth等鉴定系统和方法进行鉴定 ,具有抗菌活性的内生真菌主要分布于拟青霉属、镰孢菌属等 1 8个属中。教育部高等学校博士学科点专项科研基金资助项目 (No .96 0 384 0 2

Survey of marriage and mood of patients with spinal cord injury survived after Tangshan earthquake

目的:探讨婚姻关系对双方均为唐山地震幸存脊髓损伤(SCI)患者夫妇的生活满意度和心理状况的影响。方法:调查1976年唐山地震幸存SCI患者40名,其中,生活在截瘫康复村已婚者20名(男、女各 10 人),生活在疗养院未婚者 20 名(男、女各10人),比较婚姻状况对两组患者的生活满意度、生活质量、焦虑和抑郁情绪状况的影响。结果:已婚组 SCI患者对目前生活的满意度明显高于未婚组( P 0.05); 焦虑平均得分高于未婚组( P 0.05)。结论:婚姻对提高唐山地震幸存SCI患者的生活满意度和心理健康水平有良好作用

Expression and Localization of hnRNP A2/B1 during Differentiation of Human Osteosarcoma MG-63 Cells Induced by HMBA

背景与目的:核基质蛋白的差异表达与细胞癌变和增殖分化调控关系密切。本研究观察了hnRNP A2/B1在诱导分化处理前后人成骨肉瘤MG-63细胞核基质中的存在和分布,及其与Actin、Prohibitin的共定位关系。方法:选择性抽提经环六亚甲基双乙酰胺(hexamethylene bisacetamide,HMBA)诱导处理前后的MG-63细胞核基质,并运用双向电泳、质谱分析、蛋白质印记杂交、免疫荧光、激光共聚焦等技术检测hnRNP A2/B1在核基质中的表达与定位变化,及其与相关蛋白的共定位关系。结果:双向电泳及蛋白质印迹杂交结果证实了hnRNP A2/B1存在于MG-63细胞核基质蛋白组分中,并在HMBA处理后细胞核基质中表达下调;免疫荧光显微镜观察显示hnRNP A2/B1定位在核基质上,经HMBA处理后hnRNP A2/B1表达减弱。激光共聚焦显微镜观察结果显示,hnRNP A2/B1与细胞核基质蛋白组分Actin、细胞增殖相关调控因子Prohibitin具有共定位关系,但在诱导处理后细胞内的共定位关系减弱。结论:hnRNP A2/B1在MG-63细胞诱导分化过程中的表达分布,及其与Actin、Prohibitin的共定位关系的改变对MG-63细胞分化具有重要影响,值得进一步探索和研究。BACKGROUND & OBJECTIVE: The differentially expressed nuclear matrix proteins have great effects on canceration and regulation of cell differentiation. This study was to explore the existence and distribution of ribonucleoprotein hnRNP A2/B1 in nuclear matrix and its co-localization with Actin and Prohibitin in human osteosarcoma MG-63 cells before and after hexamethylene bisacetamide (HMBA) treatment. METHODS: The nuclear matrix of MG-63 cells before and after treatment of HMBA were selectively extracted. The expression and localization of hnRNP A2/B1 in nuclear matrix were detected by 2-D PAGE, MALDI-TOF-MS, Western blot, and immunofluorescent staining. The co-localization of hnRNP A2/B1 with Actin and Prohibitin was observed under laser scanning confocal microscope (LSCM). RESULTS: hnRNP A2/B1 was detected in the component of nuclear matrix proteins of MG-63 cells by Western blot and immunogold staining and its expression was decreased after treatment of HMBA. hnRNP A2/B1 was located in the nuclear matrix, and its expression was weakened after HMBA treatment. hnRNP A2/B1 was co-localized with Actin or Prohibitin in MG-63 cells, while the co-localization relationship was weakened during differentiation of MG-63 cells. CONCLUSIONS: hnRNP A2/B1 is a kind of nuclear matrix protein, and localizes in the nuclear matrix. The distribution and expression of hnRNP A2/B1 and its co-localization with Actin and Prohibitin play important roles during the differentiation of MG-63 cells.国家自然科学基金项目(No.30470877)~

那格列奈对2型糖尿病患者空腹游离脂肪酸的影响

【目的】探讨那格列奈对初诊2型糖尿病患者空腹游离脂肪酸的影响。【方法】42例从未进行降糖及降脂药物治疗的初诊2型糖尿病患者，随机分为那格列奈组及瑞格列奈组各21例，测定空腹游离脂肪酸（FFA）及空腹血糖（FPG）、标准餐后2h血糖（2hPG）、血脂谱，次日行静脉葡萄糖胰岛素释放试验（IVG-IRT）后，分组给予那格列奈60～90mg或瑞格列奈0．5～1．0mg，双盲治疗12周后，重复前述检查。【结果】37例完成试验，那格列奈组（18例）空腹FFA从（0．47±0．18）mmol／L下降到（0．36±0．16）mmol／L，平均下降（0．11±0．21）mmol／L（P〈0．05），瑞格列奈组（19例）空腹FFA无显著变化，那格列奈组比瑞格列奈组空腹FFA降低有明显差异。两组患者血脂谱无明显变化，治疗后FPG、2hPG、HbAlc及胰岛素抵抗指数较治疗前均有明显下降（R0．05）．胰岛B细胞功能指数（HOMA-B）、IVG-IRT 10min内急性胰岛素反应（AIR）均有明显增加（P〈0．05），组间比较无明显差异（P〉0．05）。【结论】那格列奈有降低空腹游离脂肪酸的倾向，其机制可能独立于改善胰岛功能之外

Mutagenic EFFects of Nd +3 :YAG Laser on Aspergillus Niger

本文采用nd＋3：yAg激光辐照柠檬酸生产菌黑曲霉孢子，辐照后进行培养和发酵试验、分析测定不同辐照时间黑曲霉孢子的存活率、黑曲霉菌丝体生长繁殖及代谢产酸的速度、主要代谢产物柠檬酸的产量及淀粉糖化酶活力等的变化。实验结果表明，nd＋3：yAg激光辐照后各实验组发生了不同程度的变化，说明该激光能诱发黑曲霉细胞的遗传变异，可用于诱变选育柠檬酸生产的优良高产菌株In this paper, a Nd +3 :YAG laser was used to irradiate spores of the Aspergillus niger, a citric acid-producing strain.The spores irradiated were then cultured and Fermentated.Variations in a survival rates of the spores, rates of growth, propagation, and the metabolic production acid of the hyphae, yield of the main metabolite citric acid and vitality of the saccharidase, etc .were determined and analysed.The experimental results show that the various experimental groups, irradiated by the Nd:YAG laser, had changes in diFFerent degrees.This indicates that the laser can induce Aspergillus niger cells to mutate and may possibly be applied to selectively breed new good quality strains with high yield For production of the citric acid