基于卷积神经网络的单色布匹瑕疵快速检测算法

针对布匹生产企业存在人工检测布匹瑕疵效率低、误检率、漏检率高的问题,提出一种基于深度卷积神经网络的单色布匹瑕疵检测算法.首先由于布匹瑕疵的数据规模远小于大型深度卷积神经网络的数据规模,如果采用大型卷积神经网络,计算量大且容易导致过拟合,因此设计了浅层的卷积神经网络结构;然后提出双网络并行的模型训练方法,用一个大网络指导小网络的训练过程,提高模型的训练效果;最后为了使得深度卷积神经网络模型脱离GPU的限制,能够在普通电脑、移动设备、嵌入式设备中高速运行,且保证模型检测精度,提出结合特征图优化卷积核参数的模型压缩算法.实验结果表明该算法可实现高准确率、高检测速度,在PC机的CPU模式下,检测速度为135 m/min,准确率可达到96.99%.国家自然科学基金(51605403);;2016年工信部智能制造综合标准化与新模式应用项目(2016-213

Materials Genome Initiative and Nuclear Fuel Element Material

核能由于其高能量密度和低污染排放等优点,已经成为未来能源的重要组成部分。然而,民用核燃料材料因其特殊的放射性,实验研究的安全防护成本极高,尤其是; 经过辐照后的核燃料材料,分析和表征手段极其有限,如果采用传统的试错法材料研发方法,将会使材料的研发成本大幅提高,因此,材料基因工程的研究思路正是; 适合于新型民用核燃料材料研究的技术路线。本研究组多年来以开发新型民用核燃料元件材料为目标,通过第一性原理和CALPHAD技术的结合,先后建立了U; 、Pu等锕系元素的多组元热力学数据库,并建立了辐照场作用下的热力学模型,对辐照场作用下核燃料材料的相变热力学和动力学进行了深入研究,在热力学数据; 库的基础上,运用相场动力学模型对核燃料元件材料的凝固和时效过程组织演化规律进行了系统的研究。这种基于材料基因工程的多尺度、多组元的材料设计研发思; 路为我国新一代具有自主知识产权的民用核燃料元件材料的成分设计、组织控制、工艺优化、性能改善及服役时间预测提供了重要的理论基础,同时对材料基因工程; 方法在材料开发中的广泛应用具有重要意义。Nuclear energy is an important part of the future source of energy due; to their higher energy density and lower emission of pollutants.; However, the traditional research method of "trial-and-error" may result; in higher costs and lower efficiency because of the radioactivity of the; nuclear fuel element material. The idea of Materials Genome; Initiative(MGI) is suitable for the research and development of the; nuclear fuel element material. Focused on the nuclear fuel element; material,our research group developed a multi-component thermodynamic; database including U,Pu and other elements,by coupling CALPHAD method; and the first-principle method. Based on the thermodynamic database, the; thermodynamic model under irradiation was established and the phase; transformations under irradiation were systematically investigated. The; microstructure evolutions during solidification and aging were simulated; by using the Phase-Field method. The present multiscale and; multi-component materials design method based on MGI can provide; important information for the design of composition,microstructure; controlling and property improvement of nuclear fuels materials.中央高校基本科研业务费; 国家自然科学基金资助项

Performance of lead-acid battery adding carbon nanotube in negative plate

研究添加不同含量碳纳米管(CnT)和炭黑对铅酸电池负极板电化学性能的影响。添加适量的CnT会增大负极内孔体积,改善活性材料的颗粒形态,使颗粒大小更均匀,提高电化学反应动力学性能。添加0.5%CnT时,1 C首次放电容量提高3%,并将极板2 C、60 S放电循环的寿命延长接近一倍,电池在SbA S 0101测试中的循环寿命也超过普通电池一倍。Effects of adding different amounts of carbon nanotube( CNT) and carbon black into negative plates in lead-acid battery were investigated.The negative plates with conductive carbon nanotube exhibited rich pore structure,better morphology and improved kinetic behavior.The addition of appropriate amount of CNT into negative plates was beneficial to improve discharge capacity and cycle life of the lead-acid battery under the condition of rapid charge-discharge processes.The initial discharge capacity of 1 C was increased 3%,the negative plate 2 C,60 s discharge cycle life was extended nearly doubled when adding 0.5% CNT,cycle life of the battery in SBA S 0101 test was also more than twice as ordinary battery.福建省软科学计划项目(2015R0077

基于圆周运动的自组网移动模型研究

自组网仿真研究大多基于特定的移动模型,而移动模型中节点空间概率分布是研究和评价自组网性能的理论基础.然而,现有的自组网移动模型存在诸多缺陷(如不现实的移动场景、节点的非均匀分布等).在分析和比较现有移动模型的基础上,提出一种基于圆周运动的移动模型,推导出移动节点的二维概率密度函数公式.理论分析和仿真实验表明,该模型能够克服现有移动模型的这些缺陷,为仿真和评估自组网的性能提供了精确的理论模型

Electrochemical Behavior of Vinyl Ethylene Sulfite as an Electrolyte Film-forming Additive in Lithium Ion Batteries

研究了具有不饱和双键和亚硫酸酯双官能团的乙烯基亚硫酸乙烯酯(VES)作为锂离子电池电解液成膜添加剂对中间相碳微球(CMS)和lIfEPO4电极电化学性能的影响.结果表明:在1MOl/llIClO4/PC电解液体系中,少量的VES(5%)能够在电化学过程中先于PC在CMS表面还原,形成稳定的SEI膜,明显抑制PC和溶剂化锂离子共嵌入石墨层间,改善了电池的循环性能.此外,电解液1MOl/llIClO4/PC+5%VES(V∶V)在lIfEPO4电极中展现出良好的电化学稳定性.A film-forming additive, vinyl ethylene sulfite (VES) with both vinylene group and sulfite group, affects the electrochemical performance of carbonaceous mesophase spherules (CMS) and LiFePO4 electrode.The results indicated that a small amount of VES (5%) could be reduced prior to the propylene carbonate (PC) solvent on the surface of CMS electrode in PC-based electrolyte to form a stable solid electrolyte interphase (SEI) layer, so co-intercalation of PC and solvated lithium ions to graphite could be suppressed.Furthermore, the electrolyte of 1 mol/L LiClO4/PC+5%VES (V∶V) exhibited excellent electrochemical stability in the LiFePO4 electrode.国家自然科学基金(Nos.20473068;29985310);国家“973”计划(No.2007CB209702)资助项

Classification of Panax Quinquefolium.L Samples by Cluster Analysis

建立西洋参药材分类方法;分别采用电感耦合等离子体质谱(ICP-MS)法、高效液相色谱(HPLC)法以及蒽酮-硫酸分光光度法,对12个西洋参样品中的15种无机元素、7种人参皂苷和多糖进行测定,用SPSS聚类分析法对12个西洋参样品进行聚类分析;结果表明:以4种不同的聚类变量进行聚类分析,其聚类分组结果并不一致,将几种有效成分综合为聚类变量,对西洋参进行分类更为科学合理;聚类分析法是西洋参分类分析的有效方法,对西洋参品种与质量的鉴定有一定的理论意义和实用价值。A classification method was developed for the quality assessment of Panax Quinquefolium.L.The contents of fifteen elements,seven ginsenosides and polysaccharide in twelve Panax Quinquefolium.L samples were determined by ICP-MS,HPLC and anthrone-sulfuric acid spectrophotometry,respectively.The cluster analysis was applied for the classification of 12 Panax Quinquefolium.L samples.The analysis results showed that the classified results were different with different cluster variables and it was found more reasonable to integrate several active components as cluster variables for the classification.The cluster analysis was useful for the classification of Panax Quinquefolium.L

Studies of preparation and properties of RGD-tTF water-based ferrofluids

目的探讨RGD-tTF水基磁流体通过磁场和RGD多肽在体外对内皮细胞双靶向的功能。方法通过化学沉淀法以柠檬酸钠为表面活性剂制备水基磁流体(MnFe2O4),弱酸改性后与重组的RGD-tTF融合蛋白结合,利用H-600透射电镜观测纳米粒径,以SUQID鉴定磁性,用MTT法、因子X活化检测和流式细胞仪检测RGD-tTF磁流体生物活性。结果成功制备出的水基磁流体能在磷酸盐缓冲液中稳定分布且具有生物兼容性,实验表明RGD-tTF与水基磁流体结合后对RGD和tTF生物活性均无显著影响,并证实在磁场的作用下能实现了水基磁流体对RGD-tTF的定位作用。结论一种具有内皮细胞双靶向功能的RGD-tTF水基磁流体已制备成功。 【英文摘要】 Purpose To study the property of RGD-tTF water-based ferrofluids double targeting EC304 cells in vitro by magnet and RGD peptide.Methods Water-based ferrofluids(MnFe2O4) were prepared by chemical precipitation method using citrate as surfactant, dispersed in weak acid to create surface charges,and coated with recombinant RGD-tTF protein.Proteins coated ferrofluids were characterized by H-600 transmission electron microscopy(TEM)and Superconducting Quantum Interference Device(SQUID),and its biological activi...教育部和厦门大学出国留学人员启动基金资

pJAK2 polypeptide,an antagonist of suppressors of cytokine signaling-1,can enhance the antitumor effect of dendritic cells

目的:探讨细胞因子信号转导抑制因子-1(SuPPrESSOrS Of CyTOkInE SIgnAlIng1,SOCS1)拮抗物PJAk2多肽(氨基酸序列号为1001-1013)参与树突状细胞(dEndrITIC CEllS,dCS)的体外诱导培养后对dCS抗肿瘤作用的影响。方法:采集健康人外周血,离心获得单个核细胞,用重组人粒细胞巨噬细胞集落刺激因子(rECOMbInAnT HuMAn grAnulOCyTE-MACrOPHAgE COlOny STIMulATIng fACTOr,rHgM-CSf)及重组人白细胞介素-4(rECOMbInAnT HuMAn InTErlEukIn-4,rHIl-4)诱导dCS,第5天分为4组:单纯dCS培养(对照)组、抗原负载(lySATE-dCS)组、多肽修饰(PJAk2-dCS)组和抗原与多肽共培养(lySATE+PJAk2-dCS)组,第6天各组加入肿瘤坏死因子-α(TuMOr nECrOSIS fACTOr-AlPHA,Tnf-α)促成熟。倒置显微镜下观察dCS形态;fCM法检测dCS表型;乳酸脱氢酶(lACTATE dEHydrOgEnASE,ldH)细胞毒实验检测各组细胞毒性T淋巴细胞(CyTOTOXIC T lyMPHOCyTE,CTl)对胃癌细胞bgC-823的靶向杀伤作用;ElISA法检测白细胞介素-12(InTErlEukIn-12,Il-12)和γ干扰素(InTErfErOn-γ,Ifn-γ)的水平。结果:与未加入诱导剂组相比,各组均成功诱导出成熟dCS,均高表达Cd80、Cd83、Cd86和人类白细胞dr抗原(HuMAn lEukOCyTE AnTIgEn dr,HlA-dr),但以lySATE+PJAk2-dCS组的表达水平最高。在10:1~30:1的效靶比范围内,CTl杀伤作用与效靶比呈正相关。当效靶比为30:1时,对照组的CTl杀伤率达(19.77±2.34)%,低于其他3组(P<0.01),而lySATE+PJAk2-dCS组较lySATE-dCS组及PJAk2-dCS组都高(P<0.05)。lySATE+PJAk2-dCS组培养上清液中Il-12及Ifn-γ的分泌水平明显高于对照组(P<0.01)。结论:SOCS1拮抗物PJAk2多肽(1001-1013)可增强dCS对胃癌细胞的抗原递呈及特异性抗肿瘤作用。Objective:To investigate the effect of pJAK2 polypeptide,an antagonist of SOCS1(suppressors of cytokine signaling 1),on antitumor effect of in vitro cultivation-induced DCs(dendritic cells).Methods:Peripheral blood was collected from the healthy volunteers,and the PBMCs(peripheral blood mononuclear cells)were isolated.DCs were induced by rhGM-CSF(recombinant human granulocyte-macrophage colony-stimulating factor)and rhIL-4(recombinant human interleukin-4).On the fifth day,DCs were divided into four groups:control group,Lysate-DCs group,pJAK2-DCs group,and Lysate + pJAK2 DCs group.On the sixth day,TNF-α(tumor necrosis factor-alpha)was added into each group.The morphological features of DCs were observed under an inverted microscope;the phenotypes were detected by FCM(flow cytometry);the killing effect of CTLs(cytotoxic T lymphocytes)on gastric cancer BGC-823 cells was evaluated by LDH(lactate dehydrogenase)cytotoxicity test;the concentrations of IL-12(interleukin-12)and IFN-γ(interferon-γ)were detected by ELISA(enzyme-linked immuno sorbent assay).Results:Mature DCs presented typically morphological and phenotypic features;the DCs in Lysate + pJAK2-DCs group had the highest expression levels of CD80,CD83,CD86 and HLA-DR(human leukocyte antigen DR).When the ratio of effectors to target cells ranged from 10:1 to 30:1,the killing activity of CTLs had a positive correlation with the ratio.When the ratio of effectors to target cells was 30:1,the killing activity of CTLs in the control group was(19.77±2.34)%,which was lowest as compared with the other groups(P < 0.01),meanwhile the killing activity of CTLs in Lysate + pJAK2-DCs group was higher than those in Lysate-DCs and pJAK2-DCs groups(P < 0.05).The levels of IL-12 and IFN-γ secretion in Lysate + pJAK2-DCs group were apparently higher than those in the control group(P < 0.01).Conclusion:An antagonist of SOCS1,pJAK2 polypeptide,can enhance the ability of antigen presentation and specific antitumor effect of DCs on gastric cancer cells.南京军区医学科技创新课题资助项目(编号:10MA068); 福建省自然科学基金面上项目(编号:2010D013); 厦门市科技计划创新项目(编号:3502z20104014

凡纳滨对虾养殖亲本群体遗传多样性分析

运用微卫星标记技术,选用8对微卫星引物对厦门市5个凡纳滨对虾亲虾群体(ZA1、HN、ZA2、ZP、DS)进行遗传多样性分析。结果显示,8对微卫星引物在5个凡纳滨对虾亲虾群体中共检测到75个等位基因,各群体的平均等位基因数(Na)为3. 875～7. 000、平均有效等位基因数(Ne)为2. 632～3. 719、平均PIC值范围在0. 498～0. 624。平均观测杂合度(Ho)为0. 410～0. 562、平均期望杂合度(He)为0. 589～0. 687。各群体的平均近交系数(Fis)为0. 147～0. 305,说明各群体内近交程度较高,存在杂合子缺失现象。除ZP与DS群体外,其他群体在多个微卫星位点上均显著偏离平衡(P <0. 05),说明大部分群体存在杂合子缺失现象。遗传变异分析结果显示,各群体间的遗传分化指数(Fst)为0. 028～0. 199;根据Fst计算得到各群体间的Slatkin’s遗传距离在0. 029～0. 249之间。本研究结果表明,采自厦门市的5个凡纳滨对虾亲虾群体均存在不同程度的近交现象。本文通过对厦门市5个凡纳滨对虾亲虾群体进行遗传多样性分析,旨在明确厦门市凡纳滨对虾亲虾群体的遗传结构、种质资源状况及近交程度,为该地区凡纳滨对虾种质资源的提纯、保优、复壮及遗传选育提供背景资料和建议。国家虾产业技术体系项目(CARS-48);;福建省科技厅重大专项专题项目(No:2016NZ0001-4);;厦门海洋经济创新发展示范项目(16CZY009SF05

Combined Use of Thoracoscopy and Laparoscopy in Total Laryngectomy for Cervical Esophageal Carcinoma

目的探讨胸、腹腔镜联合全喉切除治疗颈段食管的可行性和疗效。方法 2009年1月~2014年7月胸、腹腔镜联合全喉切除治疗33例颈段食管癌。胸腔镜下分离食管、腹腔镜下管胃成形、全喉切除、气管永久造口、胃咽吻合术。结果胸部手术时间40~66 MIn,平均53 MIn;腹部手术时间35~51 MIn,平均44 MIn;颈部手术时间128~150 MIn,平均139 MIn。术中出血量130~270 Ml,平均150 Ml。术后住院时间8~14 d,平均12 d。病理均为鳞状细胞癌,其中高分化2例,中分化19例,中-低分化7例,低分化5例。切缘病理学检查无癌组织残留。31例淋巴结转移。并发症:吻合口漏2例,喉返神经损伤3例,肺部感染6例,胃排空障碍2例,吻合口狭窄1例,无死亡病例。33例随访1个月~5年,术后1、3、5年生存率分别为87.9%、54.5%、45.5%。结论颈段食管癌应采取积极的手术治疗,胃咽吻合术是颈段食管癌切除后较为理想的修复手段。Objective To investigate clinical feasibility and efficacy of combined use of thoracoscopy and laparoscopy in total laryngectomy for cervical esophageal carcinoma.Methods Clinical data of 33 patients with cervical esophageal carcinoma undergoing surgical treatment in our department from January 2009 to July 2014 were analyzed retrospectively.The esophagus was separated under thoracoscopy.And laparoscopic gastroplasty,total laryngectomy,tracheal permanent colostomy,and gastric pharyngeal anastomosis were performed.Results The thoracoscopic operation time was 40- 66 min( mean,53 min),the laparoscopic operation time was 35- 51 min( mean,44 min),and the cervical operation time was 128- 150 min( mean,139 min).The blood loss was 130- 270 ml( mean,150 ml).The postoperative hospital stay was 8- 14 d( mean,12 d).Pathological examinations showed squamous cell carcinoma in all the cases,including 2 cases of highly differentiated carcinoma,19 cases of moderately differentiated carcinoma,7 cases of moderately or lowly differentiated carcinoma,and 5 cases of lowly differentiated carcinoma.No residual cancer was found at cutting edges pathologically.Among the 33 cases,lymph node metastasis was found in 31 cases.Complications included 2 cases of anastomotic fistula,3 cases of recurrent laryngeal nerve injury,6 cases of pulmonary infection,2cases of delayed gastric emptying,and 1 case of anastomotic stenosis.There was no death.All the patients were followed up for 1months to 5 years.The survival rates at 1,3,and 5 postoperative year were 87.9%,54.5%,and 45.5%,respectively.Conclusions Cervical esophageal carcinoma should be surgically treated actively.Gastric pharyngeal anastomosis is an ideal option for the repair of cervical esophageal cancer resection