p38MAPK induces apoptosis of glioma cell

目的　研究 p38MAPK基因转染大鼠胶质瘤细胞系C6后对其生物学特性的影响 .方法　利用脂质体介导法将p38MAPK基因导入大鼠胶质瘤细胞系 C6中 ,用免疫细胞化学染色检测其在细胞转染前后的表达情况 ,用 HE染色、流式细胞仪等方法研究其对细胞形态、粘着状况和生长周期的影响 .结果　转染 p CMV5 - p38MAPK质粒组 p38MAPK蛋白表达阳性 ,细胞形态发生变化 ,贴壁性降低 ,出现大量凋亡细胞 .结论　转染 p38MAPK基因可诱导胶质瘤细胞凋亡 【英文摘要】 AIM To study the effect of p38MAPK transfection on the biological characteristics of glioma cell C6. METHODS p38MAPK was transfected into glioma cell C6 by lipofectin. Expression of p38MAPK was detected by immunocytochemistry. HE staining and flow cytometry were adopted to measure the cell morphology, adhesion and cell cycle. RESULTS p38MAPK was expressed in transfected glioma cells, with cell biological characteristics changing and apoptotic cells emerging. CONCLUSION Apoptosis of glioma cell could be ...高等学校骨干教师计划资

导电涂膜表面微米尺度内痕量CIO-浓度测定方法的研究

简述采用四电极体系,锁相相关测定系统及三维微控装置,测定了电解人造海水在导电涂膜表面微米尺度内痕量C10-浓度的分布,为导电防污涂料研究的关键技术确定导电涂膜表面产生痕量C10-浓度相对应的通电参数作致关重要技术准备

Study of the Simulation of Marine Atmospheric Exposure with Lab Accelerated Test of Marine Coating Systems

通过两年海洋大气环境暴露试验、盐雾/紫外冷凝老化交替试验和氙灯老化试验,对比聚氨酯涂料、丙烯酸涂料涂层的色差和失光率,研究了3种试验对涂层表观性能的影响,发现紫外/冷凝老化加速试验对海洋大气暴露试验有很好的模拟性。The simulation of marine atmospheric exposure with lab accelerated test was studied.The lab accelerated test methods were UV-condensation and salt-fog alternant test and Xenon-Arc exposure test.The marine coating systems based on polyurethane and acrylic were compared in color difference and rate of losing gloss.The result showed that UV-condensation and salt-fog alternant test can better simulate the marine atmospheric environment than the Xenon-Arc exposure test

Study on Correlation between Marine Environmental Test and Accelerated Tests in Laboratory for Ship Coatings——Coating Systems for Marine Atmosphere

采用光泽-色泽仪、涂膜粉化率测定仪、fdIr,SEM及AfM等现代测试分析手段,对海洋大气区7种常用舰船涂料体系在实际海洋环境暴露试验以及室内人工加速老化及腐蚀试验前后的涂层性能变化进行了对比分析,并结合厦门地区的气象环境谱探索了实验室加速试验与实际海洋大气暴露试验的相关性。Seven ship coating systems were exposed in marine atmospheric environment and accelerated weathering tests in lab.Some modern analyses,such as gloss and color measurement,coat chalk rating,precise thickness meter,FDIR,SEM,AFM were applied to characterize the properties of the coating systems.The results of performance change before and after exposure were compared.The weather environmental spectrum of Xiamen area was also combined for discussion of the correlation between marine environmental exposure tests and accelerated weathering tests in lab

JUNO Sensitivity on Proton Decay p→νˉK+p\to \bar\nu K^+ Searches

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in $p\to \bar\nu K^+$ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar\nu K^+$ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is $9.6 \times 10^{33}$ years, competitive with the current best limits on the proton lifetime in this channel

JUNO sensitivity on proton decay p → ν K + searches*

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this study, the potential of searching for proton decay in the $p\to \bar{\nu} K^+$ mode with JUNO is investigated. The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar{\nu} K^+$ is 36.9% ± 4.9% with a background level of $0.2\pm 0.05({\rm syst})\pm$$0.2({\rm stat})$ events after 10 years of data collection. The estimated sensitivity based on 200 kton-years of exposure is $9.6 \times 10^{33}$ years, which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies