142 research outputs found

    An Analysis and Improvement Research on the Performance Target Setting Work in SEAL Company

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    为了应对日益激烈的竞争,企业管理者们越来越关注应如何通过改善公司的管理水平来保持竞争力,绩效管理成为管理者研究的核心问题之一。正确合理的绩效指标设定是绩效管理的重要基础,因此,本文将以绩效指标的设定过程作为研究课题,致力于发现SEAL公司当前绩效指标设定工作中常见的问题,并分析和研究出改进建议。 SEAL公司是一家行业领先的德资制造型企业。得益于总部丰富的管理经验积淀,公司已经建立起了一套相对完整的绩效管理制度。然而由于种种原因,公司的绩效指标设定环节依然存在着许多问题,对公司的运营造成了比较负面的影响。本文以SEAL公司作为研究对象,首先查阅资料汇总出绩效指标设定的相关理论依据,其次对比公...As the competition in market is much harder than before, all the managers of enterprises are focusing on how to keep the competence by improving their management skills. Performance management is one of the hottest topics to be studied. A good and efficient performance management system starts from proper targets settings, therefore the author chose performance targets setting as the objective of ...学位:工商管理硕士院系专业:管理学院_工程管理硕士学号:1792012115096

    Design and Implementation of Management System for Marine Spot Meta Data

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    近海海洋环境科学是当代近海海洋环境系统研究的前沿领域,它的研究对象是近海海洋环境系统及其整体行为,研究方法是对全球环境变化进行观测、理解、模拟和预测。这二者决定了近海海洋环境系统科学的研究对海量的、多样化的观测、探测、调查、试验数据的依赖性,以及对相关领域科学数据共享的需求。本研究课题就是基于此背景提出,通过海洋现场元数据管理系统的建设,对非结构科研数据进行结构化,提高数据信息的可用性,使得研究人员能够方便的追溯查询到科研数据产生的背景资料,便于未来多学科的科研数据分析、共享、挖掘。当前海洋现场调查缺乏相应的参考标准或者规范、调查现场混乱、无序;现场调查人员不关心科研数据在采集过程中的背景信息...Coastal Marine Environmental Science is frontier of contemporary systematic research of coastal marine environment. It targets at the research of coastal marine environment system and its total behavior through observing, understanding, stimulating and predicting global environmental changes. It greatly relies on the observation, exploration, investigation and experiment of vast and diverse data a...学位:工程硕士院系专业:软件学院_工程硕士(软件工程)学号:X201223056

    玻璃酸钠关节腔注射治疗骨关节炎疗效观察

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    我科自1998年5月至2002年10月,选择门诊及住院骨关节炎患者205例,采用玻璃酸钠(SH)关节腔注射治疗,效果良好,现报道如下。 1 资料与方法 本组205例(共221个关节),男85例(97个关节),女120例(124个关节),年龄22~92岁(平均48岁),为髌骨软化症、膝骨关节炎、创伤性膝骨关节炎、创伤性踝关节炎、肩周炎患者。病

    Credit risk assessment of enterprise basing on neural network

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    企业信用等级评估是金融领域重要的问题 ,论文采用人工神经网络模型研究企业信用等级的评估问题 .按照企业样本在信用等级的分布状况来抽样 ,然后 ,根据企业样本性质的不同 ,将其分为制造业和非制造业两大类 .利用偏相关分析方法建立了企业信用评级的指标体系 .此外 ,还介绍了几种企业信用评级常用的评估模型 ,并将神经网络评估模型的性能和其他的信用评估模型作了比较 ,实验结果表明神经网络模型具有更好的预测准确性Credit rating of the enterprise is very important problem in the financial field. In this article, we researched this problem using artificial neural network model. We got the samples basing on the distribution of credit rating of the all samples. And then, we divided the samples of the enterprises into two sets, one is manufacture and the other is non manufacture, we also developed an indicators′ system using partial correlation method. Furthermore, we introduced many credit assessment models in common use and compared the result of our model with that of some of them. The result from the experiment shows that our model is more applicable and suitable

    Controlled Release of Recombinant Ephrin-b2/Fc from Self Assembling-peptide in Myocardial Infarction Therapy

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    目的通过体外观测和体内实验探讨自聚肽rAd16-Ⅱ对EPHrIn-b2/fC重组蛋白的控制释放效应及其免疫原性,解决心肌梗死蛋白质治疗中裸露的蛋白质在机体有效作用时间短且易被降解的问题。方法体外观测rAd16-Ⅱ的塑型及对EPHrIn-b2/fC重组蛋白的控制释放;构建Sd大鼠心肌梗死模型,将存活大鼠分为2组分别予心肌内注射EPHrIn-b2/fC蛋白(E组,n=25)和自聚肽EPHrIn-b2/fC蛋白凝胶(ES组,n=25),在设定的时间点(1 H,3H,24 H,7 d,14 d)各收集心肌组织和血清样本5个,分别用免疫荧光和免疫印迹技术检测EPrHIn-b2蛋白驻留和丢失情况;皮下注射rAd16-Ⅱ,5 W后ElISA法检测血清抗体滴度,评估rAd16-Ⅱ的免疫原性。结果 rAd16-Ⅱ在PbS中可自我聚合组装成纳米纤维网状结构;这种结构在体外可使EPHrIn-b2/fC重组蛋白的释放持续144 H,其中超过50%量在120 H内释放;免疫荧光显示除注射后1 H外,EPHrIn-b2/fC蛋白在ES组的驻留量明显高于同期的E组(P<0.05);免疫印迹显示注射早期,ES组EPHrIn-b2/fC蛋白的血液释入量明显少于同期的E组(P<0.05);ElISA法检测血清抗rAd16-Ⅱ抗体效价与阴性对照组无显著差异。结论 rAd16-Ⅱ可明显地延缓EPHrIn-b2/fC重组蛋白的释放,是承载EPHrIn-b2/fC蛋白用于心肌梗死治疗和缺血性研究的较为可靠和安全的生物载体材料。Aim To explore the controlled release effect of the recombinant Ephrin-b2 /Fc chimera from self assembling peptide of RAD16-Ⅱ and the immunogenicity of RAD16-Ⅱ.Take RAD16-Ⅱas a delivery vehicle to prevent the ungroomed Ephrin-b2 / Fc protein from being degraded in vivo and increase therapeutic effect.Methods The moulding of the oligopeptide was observed by macroscopy and microscopy.The releasing effect was assayed by releasing curve obtained from test in vitro.In vivo,Sprague-Dawley rats were prepared to acute myocardial infarction models by ligation of the left anterior descending branch.The survival rats were divided into 2 groups and separately intra myocardially injected recombinant Ephrin-b2 / Fc proteins( E group,n = 25) and sapeptide- Ephrin-b2 / Fc protein complex( ES group,n = 25).At set time( 1 h,3 h,24 h,7 d,14 d),the samples of the myocardial tissue and sera were collected and respectively used for immunofluorescence and westernblot to determine the remaining or losing of the protein.RAD16-Ⅱsolution was administrated through subcutaneous injection.5 weeks later,the titer of anti-sapeptide in serum was assayed by ELISA.Results It is observed that RAD16-Ⅱsolution can self-assemble into nanofibers which fabricate net structure in condition of PBS.Within net structure,the releasing duration of chimeric Ephrin-b2 / Fc lasted up to 144 h and more than 50% mass was released in 120 h.As shown in immunofluorescence,the retention duration of the chimeric protein in ES group was significantly longer than that in E group at the same time( P < 0.05).And westernbolt also demonstrated the amount of protein releasly into blood in ES group was less significant than that in E group( P < 0.05).The titer of the antibody was not significantly different from RAD16-Ⅱ administration to negative control group,which showed that RAD16-Ⅱ would not trigger immune response.Conclusion RAD16-Ⅱ oligopeptide can postpone the release of chimeric Ephrin-b2 / Fc both in vivo and in vitro.It is a relatively reliable and safe biomaterial delivery vehicle of Ephrinb2 / Fc protein in myocardial infarction and ischemia research.福建省科技计划重点项目(2013D024

    Kr2+辐照导致的Ca8LnNa(PO4)6F2(Ln=La,Nd和Sm)磷灰石结构陶瓷材料的非晶转变

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    采用传统固相烧结法成功制备出磷灰石结构材料Ca8LnNa(PO4)6F2(Ln=La,Nd和Sm),并通过常规X射线衍射(X-ray diffraction,XRD)进行表征确定三种样品都为单一相。在室温条件下用800 keV Kr2+对三种样品进行辐照实验,辐照后的样品利用掠入射X射线衍射(grazing incidence X-ray diffraction,GIXRD)进行表征获取其表面辐照损伤层的结构信息。发现在实验辐照剂量范围内(1.0×10147.0×1014cm-2)三种样品都发生了从晶体结构到非晶结构的转变,不过三种样品的抗辐照非晶性能却有差异,抗辐照非晶能力大小关系是Ca8LaNa(PO4)6F2>Ca8NdNa(PO4)6F2>Ca8SmNa(PO4)6F2。这是由于在Ca8LnNa(PO4)6F2中,当镧系核素半径越小时,将有更大概率占据Ca(2)位置与F形成比Ca-F更弱的离子键。因此,镧系核素半径越小,辐照下将有更多的点缺陷保留下来,更容易发生非晶相变

    Lu2Ti2O7和Lu2TiO5陶瓷材料的Kr离子辐照损伤研究

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    钛酸盐因其优异的物理化学性能,可作为高放射性核废物(HLW)和锕系元素(钚)的重要候选固化材料之一。采用传统的陶瓷烧结工艺制备了多晶的Lu2Ti2O7和Lu2TiO5陶瓷材料。在室温下,用800 keV Kr2+对两种材料进行辐照,辐照后的样品采用GIXRD进行表征,观察到两种样品都经历了先肿胀、然后再发生非晶相变的过程。不同的是Lu2Ti2O7的晶格肿胀程度大于Lu2TiO5。另外,Lu2TiO5样品的辐照到2×1014ions/cm2时非晶含量达95.54%,而Lu2Ti2O7样品在此剂量下非晶含量只有74.66%。通过第一性原理计算了Lu2Ti2O7晶体的晶格肿胀随反位浓度的变化关系,结果表明,Lu2Ti2O7出现非晶前的晶格肿胀主要由阳离子反位导致,而Lu2TiO5是无序的萤石结构,其辐照所导致的晶格肿胀不含阳离子反位的贡献,晶格肿胀程度较低

    Callus Induction and Plant Regeneration in Callistemon rigidus

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    以茎段、芽和叶片为材料,探讨了红千层愈伤组织诱导及植株再生的方法.结果表明:红千层的茎段、芽和叶片均可诱导出愈伤组织,通过继代培养可发育成绿色和粉红色2种类型的愈伤组织,其中绿色、致密的愈伤组织可以分化出不定芽;培养基1/2M S+6-BA 1.0 m g/L+NAA 0.1 m g/L适宜愈伤组织不定芽的诱导,在培养基1/2M S+IBA 0.25 m g/L上试管苗的生根率可达95%.Taking stem segment,bud and leaf as materials,this paper made a study of callus induction and plant regeneration in Callistemon rigidus R.Br.The results show that callus can be induced from all types of materials and after being sub-cultured,the callus will develop to two kinds of colors that are pink and green;that the pink callus will be degenerated while the compact green one will induce adventitious buds.The optimal medium for adventitious bud inducing is 1/2 MS+6-BA 1.0 mg/L+NAA 0.1 mg/L and the optimal for the rooting of test-tube plantlets is 1/2MS+IBA0.25 mg/L on which its rate can reach 95 % after being cultured for 40 days.广东省科技计划项目(2004B60302006);; 广州市科技计划项目(004Z3-E0361)的部分研究内
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