The Effect of Distance Education on Lifelong Learning

Today's technological developments are effective in all areas of social life. One of the fields where technological developments are involved is education. With the inclusion of information and communication technologies in education and training processes, one of the concepts discussed is distance education. Since the learning process with distance education is independent of time and space, it has given birth to the concept of lifelong learning. Lifelong learning is expressed as the realization of learning wherever the individual is without any restrictions. The most important point that lifelong learning affects is equality of opportunity in education. Because lifelong learning puts the individual in the center. Therefore, by changing the role of the school, it gives importance to out-of-school learning. Thus, it supports the personal development of the learner. However, it provides benefits to society in terms of economic growth. It also emphasizes that education should not be subject to a certain time interval. Considering the advantages it provides, this skill should be included in the education system. Based on the reasons stated, in this study, the effect of distance education students on the lifelong learning tendency was examined. Quantitative research method was preferred in the study. Quasi-experimental research, which is one of the quantitative research methods, was used. Convenience sampling method was used in the research. A total of 251 participants were reached for this study with the convenient sampling method. The "Lifelong Learning Tendency" scale, which was developed in 2015, was used as a data collection tool in the research. In the analysis of the data, the independent t-test (unpaired t-test) was used to determine the differences in the pre-test and post-test scores between the groups. In line with the findings obtained as a result of the research, it was determined that the group who received education with distance education had a higher tendency to lifelong learning than the group who did not receive education with distance education. Suggestions were made in line with the results obtained

Evaluation of X-Ray Shielding Ability of Tungsten Rubber: A GAMOS Monte Carlo Study

Against the detrimental effects of ionizing radiation, time, distance, and shielding are the three most significant protective methods. Lead is the material of choice for shielding, particularly for personal protective equipment. However, lead's density, rigidity, and toxicity are significant disadvantages. In recent years, tungsten-containing rubber (TCR) and other lightweight, flexible, and non-toxic shielding materials have emerged as viable alternatives to lead. The purpose of this study is to examine the X-ray absorption capacity of TCR material, which can serve as an alternative to lead-based personal protective equipment. Using GAMOS simulation, radiation absorption characteristics for 11 different X-ray energies ranging from 30 to 1000 keV were obtained and compared with Phy-X/PSD data. While the MFP value produced from the GAMOS code for the TCR with 100 keV energy X rays was 0.0204 cm, the Phy-X/PSD value was 0.0296 cm. The HVL value of the TCR material for X-rays with an energy of 100 keV was 0.021 cm for Phy-X/PSD and 0.014 cm for GAMOS. It has been observed to provide excellent radiation protection against X-rays in the diagnostic imaging field. By providing greater flexibility than lead shielding materials, TCR can play a crucial role in decreasing radiation exposure

The Examination of Online Information Searching Strategies of Students That Use Social Network

Bu çalışmanın amacı, sosyal ağ kullanan öğrencilerin çevrimiçi bilgi arama stratejilerini, eğitim düzeyi, yaş ve günlük internet kullanım süresi açısından incelemektir. İlişkisel tarama modelinde desenlenen araştırmanın örneklemini çevrimiçi bir sosyal ağ uygulaması aracılığıyla ulaşılan 1135 katılımcı oluşturmaktadır. Araştırma verileri Demografik Özellikleri Belirleme Formu ve Çevrimiçi Bilgi Arama Stratejileri Envanteri ile toplanmıştır. Verilerin çözümlenmesinde betimsel istatistikler ve tek faktörlü varyans analizi tekniklerinden yararlanılmıştır. Araştırmanın bulgularına göre sosyal ağ kullanan öğrencilerin çevrimiçi bilgi arama stratejileri, yaş, eğitim düzeyi ve günlük internet kullanım süresi bakımından anlamlı farklılık göstermektedir. Bu anlamlı farklılığın daha net belirlenmesi ve bütüncül bir bakış açısının ortaya konması için gelecek araştırmalarda farklı sosyal ağ platformu kullanan bireyler ile birlikte sosyal ağ kullanmayan bireyler de sürece katılarak veri toplanması ve çok değişkenli istatistiksel yöntemlerden yararlanılması önerilmektedir.The purpose of this study is to determine the online information searching strategies of students that use social network by the educational level, age and daily internet use. The sample of the study designed as a relational model constitute 1135 participant achieved through the social networking application. The research data were collected with the Demographic Characteristics Form and the Online Information Searching Strategy Inventory. In data analysis, descriptive statistics and one way Anova were used. According to findings, online information searching strategies of students that use social network had significant difference in terms of educational level, age and daily internet use. Future researches are recommended with various social networking platform users and nonusers and utilization of multivariate statisticals methods to clarify this significant difference and reveal holistic perspective

Validation of a Proposed Equation for Determining the Half-Thickness Value of Gamma and X-Ray Radiation

Half-value layer (HVL) is energy dependent on the photon, much as the attenuation coefficient. Increasing the penetrating energy of a photon stream causes an increase in a substance's HVL. Before calculating the HVL value, the linear attenuation coefficient (μ) must be established. A review of the literature indicated that there is presently no Monte Carlo-based sufficient tool for direct calculation of the HVL value and direct computation suitable for material design and all changes based on sophisticated simulation methods. This study aims to calculate HVL data with GAMOS simulation in the 0.1-20 MeV energy range for some anatomical structures defined in ICRU-44 (bone cortical, brain, gray/white matter, breast tissue, eye lens, and testis). The HVL values of the anatomical structures used in the GAMOS code were compared with the results in the literature. As a result, HVL values obtained from GAMOS simulation for different materials and biological structures were compatible with the literature

Spread of Intestinal Parasites in Patients Presenting with Gastrointestinal Complaints

Objective: The aim of this study is to determine the prevalence of intestinal parasites in patients admitted to University of Health Sciences Türkiye (UHS) Van Training and Research Hospital. Methods: A total of 300 patients between the ages of 18-90 who applied to UHS Van Training and Research Hospital with gastrointestinal complaints and were referred to the parasitology laboratory between September 2021 and December 2021, and 100 patients without any chronic disease and gastrointestinal complaints in the control group were included in the study. Stool samples taken from patients included in the study and individuals in the control group were analyzed by native-lugol and modified acid-fast staining methods. Results: In the study, intestinal parasites were detected in 41 (13.3%) of 300 patients in the patient group and in seven (7%) of 100 individuals in the control group. The highest rate of Blastocystis species (Blastocystis spp.) (5.7%) was found in the patient group. Entamoeba coli 3%, G. intestinalis 2.7% and Cryptosporidium species (Cryptosporidium spp). 2.3% were found among the other species detected. In addition, a statistically significant correlation was found between the incidence of parasites and abdominal pain (p=0.022) and nausea (p=0.029). Conclusion: As a result; it was concluded that intestinal parasites are still an important health problem in patients with gastrointestinal complaints and intestinal parasites should definitely be considered in this patient group

Examination of emotion regulation in the family context: A mixed method study from Turkey

Individuals use different strategies dealing with their negative emotions and these strategies are associated with various adjustment outcomes. In the family context, parental emotion regulation strategies are also linked to the children’s emotion regulation. One aim of the current study was to examine the type of emotion regulation strategies used by parents in the Turkish cultural context. Another aim was to exploratorily investigate whether parents’ emotion regulation processes emerge in a way that predicts their children’s emotion dysregulation. One hundred seven families that had a child attending primary school participated in this study. We conducted semi-structured interviews with the parents at their homes. Child emotion dysregulation was also measured with the Emotion Regulation Checklist. Based on content analysis, the findings revealed four main themes showing a converging pattern among parents, namely non-confrontation, proactive strategies, metacognitive strategies, and dysregulated expression. In the subsequent quantitative part of the study, parental adaptiveness scores for emotion regulation strategies were calculated to examine relationships with children’s emotion dysregulation. The findings of separate hierarchical regression analyses for mothers and fathers indicated that the maternal, but not paternal, adaptiveness level in emotion regulation significantly predicted the child’s emotion dysregulation after controlling for parental education and the child’s age and gender. These qualitative and quantitative findings could contribute to the literature by drawing a comprehensive picture of emotion regulation in the family context in Turkey

Utilización del documento de consentimiento informado en la práctica odontológica pública del partido de La Plata (Argentina) - 2003

La odontología como ciencia biológica difiere del pensamiento jurídico en numerosos puntos. La biología es a menudo variante. Por lo tanto el razonamiento biológico lleva implícito una parte de reserva, de incertidumbre y de duda. Por el contrario el pensamiento jurídico tiene que responder a los textos que lo instituyen como los códigos y las leyes, que son de elaboración humana, por lo tanto discernibles y asimilables. Desde la época que el hombre realizaba investigaciones empíricas, hasta nuestros días, han concurrido ciencias y disciplinas de investigación que han generado el crecimiento de diferentes especialidades, aportando elementos que definen y caracterizan su campo de acción. La Odontología Legal, como cualquier rama de la ciencia, es un producto de la evolución del hombre. Por lo tanto varía con el tiempo, es distinta según los estados o los países. El Derecho moderno establece una colaboración entre la ciencia y la ley. En estos casos el grado de responsabilidad del odontólogo es alto, porque tiene la función de auxiliar con sus conocimientos, donde sus dichos pueden influir con fuerza sobre el fallo del magistrado. Es preciso, actualmente que el perito odontólogo, adquiera un cúmulo de conocimientos sobre el espíritu jurídico y los procedimientos a seguir en los distintos fueros.Facultad de Odontología (FOLP

Systems-level analysis reveals multiple modulators of epithelial-mesenchymal transition and identifies DNAJB4 and CD81 as novel metastasis inducers in breast cancer

Epithelial-mesenchymal transition (EMT) is driven by complex signaling events that induce dramatic biochemical and morphological changes whereby epithelial cells are converted into cancer cells. However, the underlying molecular mechanisms remain elusive. Here, we used mass spectrometry based quantitative proteomics approach to systematically analyze the post-translational biochemical changes that drive differentiation of human mammary epithelial (HMLE) cells into mesenchymal. We identified 314 proteins out of more than 6,000 unique proteins and 871 phosphopeptides out of more than 7,000 unique phosphopeptides as differentially regulated. We found that phosphoproteome is more unstable and prone to changes during EMT compared with the proteome and multiple alterations at proteome level are not thoroughly represented by transcriptional data highlighting the necessity of proteome level analysis. We discovered cell state specific signaling pathways, such as Hippo, sphingolipid signaling, and unfolded protein response (UPR) by modeling the networks of regulated proteins and potential kinase-substrate groups. We identified two novel factors for EMT whose expression increased on EMT induction: DnaJ heat shock protein family (Hsp40) member B4 (DNAJB4) and cluster of differentiation 81 (CD81). Suppression of DNAJB4 or CD81 in mesenchymal breast cancer cells resulted in decreased cell migration in vitro and led to reduced primary tumor growth, extravasation, and lung metastasis in vivo. Overall, we performed the global proteomic and phosphoproteomic analyses of EMT, identified and validated new mRNA and/ or protein level modulators of EMT. This work also provides a unique platform and resource for future studies focusing on metastasis and drug resistanceTurkiye Cumhuriyeti Kalkinma Bakanlig

The frequency of Duchenne muscular dystrophy/Becker muscular dystrophy and Pompe disease in children with isolated transaminase elevation: results from the observational VICTORIA study

IntroductionElevated transaminases and/or creatine phosphokinase can indicate underlying muscle disease. Therefore, this study aims to determine the frequency of Duchenne muscular dystrophy/Becker muscular dystrophy (DMD/BMD) in male children and Pompe disease (PD) in male and female children with isolated hypertransaminasemia.MethodsThis multi-center, prospective study enrolled patients aged 3–216 months with serum alanine transaminase (ALT) and/or aspartate transaminase (AST) levels >2× the upper limit of normal (ULN) for ≥3 months. Patients with a known history of liver or muscle disease or physical examination findings suggestive of liver disease were excluded. Patients were screened for creatinine phosphokinase (CPK) levels, and molecular genetic tests for DMD/BMD in male patients and enzyme analysis for PD in male and female patients with elevated CPK levels were performed. Genetic analyses confirmed PD. Demographic, clinical, and laboratory characteristics of the patients were analyzed.ResultsOverall, 589 patients [66.8% male, mean age of 63.4 months (standard deviation: 60.5)] were included. In total, 251 patients (188 male and 63 female) had CPK levels above the ULN. Of the patients assessed, 47% (85/182) of male patients were diagnosed with DMD/BMD and 1% (3/228) of male and female patients were diagnosed with PD. The median ALT, AST, and CPK levels were statistically significantly higher, and the questioned neurological symptoms and previously unnoticed examination findings were more common in DMD/BMD patients than those without DMD/BMD or PD (p < 0.001).DiscussionQuestioning neurological symptoms, conducting a complete physical examination, and testing for CPK levels in patients with isolated hypertransaminasemia will prevent costly and time-consuming investigations for liver diseases and will lead to the diagnosis of occult neuromuscular diseases. Trial RegistrationClinicaltrials.gov NCT04120168