Promjena nekih biokemijskih vrijednosti u Honamli koza i dugodlakih koza u vrijeme spolnog sazrijevanja.

Honamlı goats have been defined and recorded as a new breed but the literature is very limited on these goats. In terms of meat production, they have been reported as having some of the highest potential among the goat breeds in Turkey. The aim of the present study was to determine the alterations in blood serum chemistry values in the puberty period in Honamlı and Native Hair goats. Selected biochemistry parameters were chosen due to their association with meat production potential. Blood samples of Honamlı (n = 90, 45 animals for each sex) and Native Hair goats (n = 90, 45 animals for each sex) were obtained from goat herds in the Western Mediterranean region of Turkey. The values of alkaline phosphatase (ALP), alanine transaminase (ALT), aspartate transaminase (AST), creatine kinase (CK), calcium, cholesterol, creatinine, iron, magnesium, phosphorus, total lipids, triglycerides and uric acid were measured in the sera obtained from blood samples of males and females in equal numbers of each species, in the three age groups of 4, 8 and 12 months. One-way analysis of variance and the Tukey test were performed for statistical evaluation. In both male and female animals, ALT, AST, CK, calcium, cholesterol, creatinine, iron, magnesium, phosphorus, total lipids, triglycerides and uric acid levels exhibited significant (P<0.05) differences between the age groups. Our findings suggest that there are age-associated parallel increases of ALT values in female goats and total lipid values in male goats. The present study also reveals that the analyzed biochemical values usually change after 4 months of age when compared with the other age groups.Honamli koza je nova pasmina koza pa su literaturni podatci o njoj vrlo oskudni. Jedna je od pasmina s najvećim mogućnostima za proizvodnju mesa u Turskoj. Cilj je ovog rada odrediti promjene biokemijskih vrijednosti u krvnom serumu Honamli koza i dugodlakih koza za vrijeme spolnog sazrijevanja. Za istraživanje su odabrani neki biokemijski pokazatelji povezani s proizvodnjom mesa. Uzorci krvi Honamli koza (n = 90, po 45 životinja oba spola) i dugodlakih koza (n = 90, po 45 životinja oba spola) uzeti su od stada u Zapadnom Mediteranskom području Turske. Vrijednosti alkalne fosfataze (ALP), alanin transaminaze (ALT), aspartat transaminaze (AST), kreatin kinaze (CK), kalcija, kolesterola, kreatinina, željeza, magnezija, fosfora, ukupnih lipida, triglicerida i mokraćne kiseline izmjerene su u uzorcima seruma uzetima od muških i ženskih životinja obiju pasmina podijeljenih u skupine prema dobi od 4, 8 i 12 mjeseci. Jednostavna analiza varijance i Tukeyev test rabljeni su za statističku obradbu podataka. I u muških i u ženskih životinja ustanovljene su značajne razlike (P<0,05) među dobnim skupinama za razine ALT, AST, CK, kalcija, kolesterola, kreatinina, željeza, magnezija, fosfora, ukupnih lipida, triglicerida i mokraćne kiseline. Nalazi pokazuju usporedno povećanje vrijednosti ALT u ženskih životinja i vrijednosti ukupnih lipida u muških životinja. Analizirane biokemijske vrijednosti obično se mijenjaju nakon 4 mjeseca starosti u usporedbi s drugim dobnim skupinama

TÜRKİYE'DE 1990 SONRASI ÇEVRE POLİTİKALARININ SEÇİM BEYANNAMELERİNE YANSIMALARI

Ülkemizde çevre farkındalığının 1970’li yıllarda artışından söz edilebilirse de çevre, siyasi partilerin söylem ve gündemlerine daha sonraki yıllarda girmiştir. Çevre kirliliğinin artışına paralel olarak dünya genelinde giderek daha fazla tartışılan bir konu olan çevre ve çevrenin korunması 1990’lı yıllardan itibaren siyasi gündemin daha önemli bir parçası ve siyasi partilerin daha fazla üzerinde durdukları bir konu haline gelmiştir. Genel ve yerel seçimler öncesinde açıkladıkları beyannamelerle bir konu ile ilgili yaptıklarını ve yapacaklarını yani hizmetlerini ve vaatlerini kamuoyu ile paylaşan siyasi partilerin beyannamelerde bir konuya yer verip vermemelerinin yanı sıra ne ağırlıkta yer verdikleri de önem taşır. Çünkü partilerin seçim sürecinde üzerinde durdukları konuların kamusal gündemin üst sıralarına taşınma ihtimali de artacaktır. Çevre sorunlarının çözümünde önemli aktörler olan siyasi partilerin seçim beyannamelerindeki çevre bölümlerinin genel bir portresini ortaya koymayı amaçlayan bu çalışmada, 1990 yılı sonrasında gerçekleştirilen genel ve yerel seçimlerde siyasi partilerin seçim beyannameleri, çevre konularına verdikleri önem bakımından incelenmiştir

Proton induced reaction cross section measurements on Se isotopes for the astrophysical p process

As a continuation of a systematic study of reactions relevant to the astrophysical p process, the cross sections of the 74,76Se(p,gamma)75,77Br and 82Se(p,n)82Br reactions have been measured at energies from 1.3 to 3.6 MeV using an activation technique. The results are compared to the predictions of Hauser-Feshbach statistical model calculations using the NON-SMOKER and MOST codes. The sensitivity of the calculations to variations in the optical proton potential and the nuclear level density was studied. Good agreement between theoretical and experimental reaction rates was found for the reactions 74Se(p,gamma)75Br and 82Se(p,n)82Br.Comment: 9 pages, 6 figures (in 12 eps files), accepted for publication in Phys. Rev C, RevTeX styl

Measurements of proton induced reaction cross sections on 120Te for the astrophysical p-process

The total cross sections for the 120Te(p,gamma)121I and 120Te(p,n)120I reactions have been measured by the activation method in the effective center-of-mass energies between 2.47 MeV and 7.93 MeV. The targets were prepared by evaporation of 99.4 % isotopically enriched 120Te on Aluminum and Carbon backing foils, and bombarded with proton beams provided by the FN tandem accelerator at the University of Notre Dame. The cross sections and $S$ factors were deduced from the observed gamma ray activity, which was detected off-line by two Clover HPGe detectors mounted in close geometry. The results are presented and compared with the predictions of statistical model calculations using the codes NON-SMOKER and TALYS.Comment: 17 pages, 5 figures, 5 tables, regular articl

An Extracellular Interactome of Immunoglobulin and LRR Proteins Reveals Receptor-Ligand Networks

Extracellular domains of cell surface receptors and ligands mediate cell-cell communication, adhesion, and initiation of signaling events, but most existing protein-protein “interactome” data sets lack information for extracellular interactions. We probed interactions between receptor extracellular domains, focusing on a set of 202 proteins composed of the Drosophila melanogaster immunoglobulin superfamily (IgSF), fibronectin type III (FnIII), and leucine-rich repeat (LRR) families, which are known to be important in neuronal and developmental functions. Out of 20,503 candidate protein pairs tested, we observed 106 interactions, 83 of which were previously unknown. We “deorphanized” the 20 member subfamily of defective-in-proboscis-response IgSF proteins, showing that they selectively interact with an 11 member subfamily of previously uncharacterized IgSF proteins. Both subfamilies interact with a single common “orphan” LRR protein. We also observed interactions between Hedgehog and EGFR pathway components. Several of these interactions could be visualized in live-dissected embryos, demonstrating that this approach can identify physiologically relevant receptor-ligand pairs

Turner syndrome and associated problems in turkish children: A multicenter study

Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology

Test of statistical model cross section calculations for α -induced reactions on Ag 107 at energies of astrophysical interest

Background: Astrophysical reaction rates, which are mostly derived from theoretical cross sections, are necessary input to nuclear reaction network simulations for studying the origin of p nuclei. Past experiments have found a considerable difference between theoretical and experimental cross sections in some cases, especially for (α,γ) reactions at low energy. Therefore, it is important to experimentally test theoretical cross section predictions at low, astrophysically relevant energies. Purpose: The aim is to measure reaction cross sections of Ag107(α,γ)In111 and Ag107(α,n)In110 at low energies in order to extend the experimental database for astrophysical reactions involving α particles towards lower mass numbers. Reaction rate predictions are very sensitive to the optical model parameters and this introduces a large uncertainty into theoretical rates involving α particles at low energy. We have also used Hauser-Feshbach statistical model calculations to study the origin of possible discrepancies between prediction and data. Method: An activation technique has been used to measure the reaction cross sections at effective center of mass energies between 7.79 MeV and 12.50 MeV. Isomeric and ground state cross sections of the (α,n) reaction were determined separately. Results: The measured cross sections were found to be lower than theoretical predictions for the (α,γ) reaction. Varying the calculated averaged widths in the Hauser-Feshbach model, it became evident that the data for the (α,γ) and (α,n) reactions can only be simultaneously reproduced when rescaling the ratio of γ to neutron width and using an energy-dependent imaginary part in the optical α+Ag107 potential. Conclusions: The new data extend the range of measured charged-particle cross sections for astrophysical applications to lower mass numbers and lower energies. The modifications in the model predictions required to reproduce the present data are fully consistent with what was found in previous investigations. Thus, our results confirm the previously suggested energy-dependent modification of the optical α+nucleus potential.Peer reviewedFinal Accepted Versio

Odd p isotope 113In: Measurement of alpha-induced reactions

One of the few p nuclei with an odd number of protons is 113In. Reaction cross sections of 113In(alpha,gamma)117Sb and 113In(alpha,n)116Sb have been measured with the activation method at center-of-mass energies between 8.66 and 13.64 MeV, close to the astrophysically relevant energy range. The experiments were carried out at the cyclotron accelerator of ATOMKI. The activities were determined by off-line detection of the decay gamma rays with a HPGe detector. Measured cross sections and astrophysical S factor results are presented and compared with statistical model calculations using three different alpha+nucleus potentials. The comparison indicates that the standard rates used in the majority of network calculations for these reactions were too fast due to the energy dependence of the optical alpha potential at low energy.Comment: 9 pages, 9 figures, Accepted for publication in Phys. Rev. C. Minor changes mad