97 research outputs found
Percepciones en México sobre la Importancia de la educación universitaria para mujeres. Un comparativo
El objetivo es analizar las actitudes respecto a la importancia de los estudios universitarios para mujeres en México a partir de la Encuesta Mundial de Valores 2018-2022. El procedimiento inicial es un ejercicio descriptivo de la postura excluyente contra las mujeres y posteriormente un análisis transversal para comparar cinco periodos con países de América. Con un análisis de dispersión entre la tasa de participación de mujeres en estudios superiores por cada país y el porcentaje más alto de la categoría de la variable dependiente se ofrece una explicación relacional. Por último, mediante dos procedimientos multivariados (análisis de componentes principales y análisis de correspondencias múltiples), se extraen los factores influyentes de un conjunto de variables de control y se analizan las proximidades de las categorías extraídas con las actitudes excluyentes. Los resultados señalan que, a pesar de la tendencia progresiva hacia poca prevalencia de actitudes discriminantes, comparativamente con países americanos se destaca el alto porcentaje de población que señala juicios excluyentes. Se demuestra que entre menor tasa de participación de mujeres en espacios universitarios es mayor la proporción de opiniones discriminantes. Por último, existe proximidad entre la opinión discriminante con categorías de niveles bajos educativos, clases social baja y edades mayores. Al final se discuten los resultados y sus implicaciones
Isotopic study of the influence of oxygen interaction and surface species over different catalysts on the soot removal mechanism
In order to improve the catalytic formulations for soot removal in after-treatment emission control technologies for gasoline and diesel engine vehicle, an isotopic study was approached using transitory labeled oxygen response method over model catalysts that allows the unraveling of soot oxidation mechanism. Ce-based materials promote oxygen exchange associated with the high population of lattice oxygen species (O2-) denoted as OI type. The incorporation of praseodymium produces a Pr3+ enrichment that decrease the energy for oxygen release and increase oxygen mobility through surface and subsurface oxygen centers (OII type) depending on the synthesis procedure. For PtBaK catalyst, OIII species are responsible for oxygen exchange. Gas-solid reaction between soot and gas phase molecular oxygen is responsible for direct uncatalyzed soot oxidation. For ceria containing catalysts, low-temperature soot removal takes place through the intervention of lattice atomic species and superoxide species. For DPNR model catalyst, PtBaK/Al2O3, the soot elimination occurs with the intervention OIII type centers. In the presence NO, the assisted and cooperative mechanism due to NO2 and the intervention of the adsorbed nitrate species on the trimetallic catalyst enhances soot removal capacity.MCR acknowledges the postdoctoral fellowship obtained from the University of Malaga. MCR, CH, MAL and LJA want to thank the financial support of CTQ 2017-87909R project. MCR also want to thank the University of Alicante for the financial support for the internship (INV19-07). JCMM and AGG gratefully acknowledge the financial support of Generalitat Valenciana (PROMETEO/2018/076 project) and the Spanish Ministry of Science, Innovation and Universities (PID2019-105542RB-I00 project) and the UE-FEDER funding. JCMM also acknowledges Spanish Ministry of Science, Innovation and Universities for the financial support through a FPU grant (FPU17/00603)
Isotopic study of the influence of oxygen interaction and surface species over different catalysts on the soot removal mechanism
In order to improve the catalytic formulations for soot removal in after-treatment emission control technologies for gasoline and diesel engine vehicle, an isotopic study was approached using transitory labeled oxygen response method over model catalysts that allows the unraveling of soot oxidation mechanism. Ce-based materials promote oxygen exchange associated with the high population of lattice oxygen species (O2-) denoted as OI type. The incorporation of praseodymium produces a Pr3+ enrichment that decrease the energy for oxygen release and increase oxygen mobility through surface and subsurface oxygen centers (OII type) depending on the synthesis procedure. For PtBaK catalyst, OIII species are responsible for oxygen exchange. Gas-solid reaction between soot and gas phase molecular oxygen is responsible for direct uncatalyzed soot oxidation. For ceria containing catalysts, low-temperature soot removal takes place through the intervention of lattice atomic species and superoxide species. For DPNR model catalyst, PtBaK/Al2O3, the soot elimination occurs with the intervention of OIII type centers. In the presence NO, the assisted and cooperative mechanism due to NO2 and the intervention of the adsorbed nitrate species on the trimetallic catalyst enhances soot removal capacity.MCR acknowledges the postdoctoral fellowship obtained from the University of Malaga. MCR, CH, MAL and LJA want to thank the financial support of CTQ 2017-87909R project. MCR also want to thank the University of Alicante for the financial support for the internship (INV19-07). JCMM and AGG gratefully acknowledge the financial support of Generalitat Valenciana (PROMETEO/2018/076 project) and the Spanish Ministry of Science, Innovation and Universities (PID2019-105542RB-I00 project) and the UE-FEDER funding. JCMM also acknowledges Spanish Ministry of Science, Innovation and Universities for the financial support through a FPU grant (FPU17/00603)
Occurrence and transport of microplastics sampled within and above the planetary boundary layer
Nowadays, there is no direct evidence about the presence of microplastics (MPs) in the atmosphere above ground level. Here, we investigated the occurrence, chemical composition, shape, and size of MPs in aircraft sampling campaigns flying within and above the planetary boundary layer (PBL). The results showed that MPs were present with concentrations ranging from 1.5 MPs m−3 above rural areas to 13.9 MPs m−3 above urban areas. MPs represented up to almost one third of the total amount of microparticles collected. Fourier Transform Infrared Spectroscopy allowed identifying seven types of MPs with the highest diversity corresponding to urban areas. Atmospheric transport and deposition simulations were performed using the HYbrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model. Air mass trajectory analyses showed that MPs could be transported more than 1000 km before being deposited. This pioneer study is the first evidence of the microplastic presence above PBL and their potential long-range transport from their point of release even crossing distant bordersWe also acknowledge support from the EnviroPlaNet Network Thematic Newtork of Micro- and Nanoplastics in the Environment (RED2018-102345-T; Ministerio de Ciencia, Innovación y Universidades). We thank the financial support provided by the Spanish Ministerio de Ciencia, Innovación y Universidades (CTM2016-74927-C2-1-R/2-R, CGL2015-69758-P, CGL2017-92086-EXP, RTI2018-094867-B-I00) and National Institute for Aerospace Technology (PAI/APL/001/09
Occurrence and transport of microplastics sampled within and above the planetary boundary layer.
Nowadays, there is no direct evidence about the presence of microplastics (MPs) in the atmosphere above ground level. Here, we investigated the occurrence, chemical composition, shape, and size of MPs in aircraft sampling campaigns flying within and above the planetary boundary layer (PBL). The results showed that MPs were present with concentrations ranging from 1.5 MPs m−3 above rural areas to 13.9 MPs m−3 above urban areas. MPs represented up to almost one third of the total amount of microparticles collected. Fourier Transform Infrared Spectroscopy allowed identifying seven types of MPs with the highest diversity corresponding to urban areas. Atmospheric transport and deposition simulations were performed using the HYbrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model. Air mass trajectory analyses showed that MPs could be transported more than 1000 km before being deposited. This pioneer study is the first evidence of the microplastic presence above PBL and their potential long-range transport from their point of release even crossing distant borders.We also acknowledge support from the EnviroPlaNet Network Thematic Newtork of Micro- and Nanoplastics in the Environment (RED2018-102345-T; Ministerio de Ciencia, Innovación y Universidades). We thank the financial support provided by the Spanish Ministerio de Ciencia, Innovación y Universidades (CTM2016-74927-C2-1-R/2-R, CGL2015-69758-P, CGL2017-92086-EXP, RTI2018-094867-B-I00) and National Institute for Aerospace Technology (PAI/APL/001/09)
Lung cancer in Spain: information from the Thoracic Tumors Registry (TTR study)
[Background] Lung cancer remains a leading cause of cancer incidence and mortality worldwide. Although Spain contributes to global statistics related to cancer, it is difficult to discern aspects linked to clinical presentation of the disease or molecular testing. The Thoracic Tumor Registry (TTR) was created with the aim of filling this gap.[Methods] Observational cohort multicenter study performed in Spain, including patients with lung cancer or other types of thoracic tumors undergoing active treatment or palliative care only. Enrollment took place between August 2016 and December 2018. The evaluation included a review of demographic, epidemiological, clinical and molecular data.[Results] A total of 6,600 patients diagnosed with non-small cell lung cancer (NSCLC) were recruited at 56 Spanish hospitals. The mean age at diagnosis was 64 years. The majority of patients (80%) presented with advanced disease, being adenocarcinoma the most frequent histological type. Up to 86% of patients were current- or ex-smokers, with men starting to smoke earlier than women (average age 17.9 vs. 19.2 years). Sixty-seven percent of patients underwent some type of molecular testing. Mutations in EGFR and KRAS genes were found in 18% and 28% of patients, respectively.[Conclusions] Our findings suggest that the TTR study accurately describes the clinical reality of lung cancer in Spain, including useful information on smoking status as well as molecular profiling and tumor histology, and can therefore be used to drive improvements in health care. Social and political pressure to reduce tobacco consumption among the population should be reinforced, particularly among youth.This work was supported by Grupo Español de Cáncer de Pulmón (GECP), Novartis, Lilly and Merck Sharp & Dohme (MSD)
Impacto de la innovación en la docencia y el aprendizaje de los estudiantes del Grado de Farmacia: Aplicación al Servicio Profesional Farmacéutico de los Sistemas Personalizados de Dosificación. Impacto de la innovación en la docencia y el aprendizaje de los estudiantes del Grado de Farmacia
Se analizó el impacto de la innovación en la docencia y el aprendizaje de los estudiantes del Grado de Farmacia (n=344). La actuación innovadora supuso realizar un estudio "pre" y "post" a los Grupos Intervención y un estudio "post" a los Grupos Control. Las preguntas-guía aplicadas fueron un total de siete. No se encontraron diferencias estadísticamente significativas entre los dos grupos (p=0,1484), pero si entre las puntuaciones medianas obtenidas en las preguntas-guía 5, 6 y 7
Dietary Compounds as Epigenetic Modulating Agents in Cancer
Epigenetic mechanisms control gene expression during normal development and their aberrant regulation may lead to human diseases including cancer. Natural phytochemicals can largely modulate mammalian epigenome through regulation of mechanisms and proteins responsible for chromatin remodeling. Phytochemicals are mainly contained in fruits, seeds, and vegetables as well as in foods supplements. These compounds act as powerful cellular antioxidants and anti-carcinogens agents. Several dietary compounds such as catechins, curcumin, genistein, quercetin and resveratrol, among others, exhibit potent anti-tumor activities through the reversion of epigenetic alterations associated to oncogenes activation and inactivation of tumor suppressor genes. In this review, we summarized the actual knowledge about the role of dietary phytochemicals in the restoration of aberrant epigenetic alterations found in cancer cells with a particular focus on DNA methylation and histone modifications. Furthermore, we discussed the mechanisms by which these natural compounds modulate gene expression at epigenetic level and described their molecular targets in diverse types of cancer. Modulation of epigenetic activities by phytochemicals will allow the discovery of novel biomarkers for cancer prevention, and highlights its potential as an alternative therapeutic approach in cancer
Biomass Accumulation and Carbon Storage in Pinus maximinoi, Quercus robur, Quercus rugosa, and Pinus patula from Village- Forests of Chiapas, Mexico
The Frailesca region (Chiapas, Mexico) presents a lack of forest studies and its environmental contribution. This chapter displays a first case study with preliminary research information regarding the identification of main forest trees and rural villages with best potential for biomass production and carbon storage management. Twenty two plots of 500 m2 were selected in 11 villages of the region, in order to identify the main and dominant forest trees species and then to estimate the biomass production and carbon storage in pine (Pinus maximinoi), oak (Quercus robur), holm oak (Quercus rugosa) and Mexican weeping pine (Pinus patula) species. This study shows that the largest accumulation of both biomass and carbon occurred in the pine forests and the lowest in the oak forests. Pine trees showed carbon storage of 516.75 Mg ha−1, followed by holm oaks, with 297.21 Mg ha−1; the species with the lowest value was oak, with 75.02 Mg ha−1. The forests of the 24 de Febrero villages had the highest potential for carbon storage. Deep studies are being conducted in relation to the aboveground biomass, carbon contents in trees stem, branches and leaves, and the relation to biomass dynamics and carbon stocks and other ecological aspects of village-forests
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