341 research outputs found
Bivariate orthogonal polynomials in the Lyskova class
AbstractClassical orthogonal polynomials in two variables can be characterized as the polynomial solutions of a matrix second-order partial differential equation involving matrix polynomial coefficients. In this work, we study classical orthogonal polynomials in two variables whose partial derivatives satisfy again a second-order partial differential equation of the same type
Semiclassical orthogonal polynomials in two variables
AbstractIn this work, semiclassical orthogonal polynomials in two variables are defined as the orthogonal polynomials associated with a quasi definite linear functional satisfying a matrix Pearson-type differential equation. Semiclassical functionals are characterized by means of the analogue of the structure relation in one variable. Moreover, non trivial examples of semiclassical orthogonal polynomials in two variables are given
Spatial and temporal dynamics of nutrients during the first filling years of a Mediterranean reservoir
Se ha estudiado la evolución espacio-temporal de variables limnológicas clásicas en un embalse mediterráneo: Rules, en la provincia
de Granada, tras su inauguración. La dinámica de los nutrientes y de la clorofila-a está fuertemente condicionada por: (i) los aportes
a través de las aguas fluviales; (ii) la actividad fotosintética en las capas superiores de la columna de agua y (iii) la acumulación
de ortofosfato y de amonio en el hipolimnion anóxico durante la estratificación térmica. La tasa de sedimentación en el embalse
de Rules muestra un claro gradiente creciente en el sentido presa-cola, reflejando la importante contribución de material alóctono
fluvial. Finalmente, la comparación de las concentraciones totales de fósforo y nitrógeno tras 10 años de funcionamiento, en los
que, entre otros factores, ha mejorado la depuración de aguas residuales en la cuenca de captación, ha mostrado una drástica
disminución.The spatio-temporal evolution of classical limnological variables has been studied in a Mediterranean reservoir: Rules, in the province
of Granada, after its inauguration. The dynamics of nutrients and chlorophyll-a is strongly conditioned by: (i) contributions through
fluvial waters; (ii) the photosynthetic activity in the upper layers of the water column and (iii) the accumulation of orthophosphate
and ammonium in the anoxic hypolimnion during summer thermal stratification. The sedimentation rate in Rules Reservoir shows a
clear increasing gradient in the dam-tail direction, reflecting the important contribution of allochthonous fluvial material. Finally, the
comparison of the total concentrations of phosphorus and nitrogen after 10 years of operation, in which, among other factors, the
purification of wastewater in the catchment basin has improved, has shown a drastic decreas
Percepción de esfuerzo en Educación Física y su relación con las directrices sobre actividad física
Epistemological approach to translation and accessibility in the digital context: a taxonomy proposal
Las modalidades de Traducción e Interpretación Accesible
(TeIA) han sido amplio objeto de investigación desde
los estudios de Traducción Audiovisual (Díaz Cintas
2007a; Orero 2007; Álvarez de Morales et al., 2012).
Sin embargo, su delimitación en el contexto digital se
encuentra en un estado aún propedéutico (Greco 2019:
19). En el siguiente artículo realizamos una reflexión
sobre la revisión bibliográfica (Jiménez Hurtado 2007;
Tercedor et al., 2007a; Báez Montero 2010; Martínez
2015; Cabezas Gay 2017; Medina Reguera 2018) para
delimitar su ubicación epistemológica dentro del contexto
específico de estudio, definiendo las particularidades
que distinguen a las modalidades de TeIA y aportando
finalmente una propuesta de taxonomía específica que
incluye la descripción verbal, la interpretación a códigos
visuales gestuales, la transcripción y la adaptación
textual. Su análisis y estudio como elementos del Diseño
Universal es clave para profundizar en la implementación
de soluciones de accesibilidad efectivas para los todos
los usuarios.Accessible Translation and Interpreting Modalities
have been extensively researched by the Audiovisual
Translation Studies (Díaz Cintas 2007a; Orero
2007; Álvarez de Morales et al., 2012). However, its
delimitation in the digital context is still in a propaedeutic
stage (Greco 2019: 19). In the following article,
we study the bibliographic review (Jiménez Hurtado
2007; Tercedor et al., 2007a; Báez Montero 2010;
Martínez 2015; Cabezas Gay 2017; Medina Reguera
2018) according to the last Audiovisual Modalities
in Translation and Interpreting in order to delimit its
epistemological location within the specific context of
study, in one hand, we will define the particularities that
distinguish them and, on the other hand, we will provide
a proposal for a specific taxonomy that includes the
verbal description, the interpretation of visual-gestural
codes and the transcription and the text adaption. Its
analysis and further research, considered as elements of
Universal Design, is key to deepen the implementation
of effective accessibility solutions for all users
Public building works in the Municipal Archives of Santa Fe: The architect Francisco Fábregas Vehil (1925-1934)
Santa Fe inicia la remodelación de su edilicia pública durante la Dictadura de Primo de Rivera a raíz de tres decisiones municipales: construir un local apropiado para las Escuelas, un nuevo Ayuntamiento, y modernizar la imagen de la ciudad ante la celebración de la Exposición Iberoamericana de Sevilla en 1929. El proyecto (Casa Consistorial, Mercado con Matadero, Escuelas, Pavimentación y Alcantarillado, y dos Lavaderos) se encarga a la empresa “Técnica de Construcción, S.A” y a su arquitecto Francisco Fábregas Vehil, quien realizó los proyectos y dirigió las obras desde Sevilla y Barcelona hasta bien entrada la Segunda República.Rebuilding work in Santa Fe started during the Primo de Rivera Dictatorship, as a consequence of three municipal decisions: to build an appropriate building to house the schools; to construct a new Town Hall, and to give the town a look of modernity, given the imminent celebration of the Latin American Exhibition in Seville in 1929. The contract (for the town hall, the market and slaughterhouse, schools, paving and drainage work) was given to the firm “Técnica de Construcción, S.A” and their chief architect Francisco Fábregas Vehil, who carried out the project and supervised the building work from Seville and Barcelona, until well into the Spanish Second Republic
Bibliografía [Cuadernos del Instituto Antonio de Nebrija de estudios sobre la Universidad. 2003, nº 6]
Publicad
El niño enfermo en los textos médicos andalusíes
El objeto de este trabajo es contribuir al conocimiento de la figura
del riiño ;.oriio objeto de atención rriédica en una cultura rio suficienterrierite
estudiada: la hispano-árabe. Para ello utilizamos textos niédicos,
rriuchos de ellos inéditos, o poco conocidos los más, en un interito de
corripc.ridiar los supuestos teóricos sobre la patología de la infancia y su
terapkutica eri sus vertientes niágica, rriedicanientosa y quirúrgica, así
corno los aspectos importantes de prevención de la enfermedad
Characterization of New Proteomic Biomarker Candidates in Mucopolysaccharidosis Type IVA
Mucopolysaccharidosis type IVA (MPS IVA) is a lysosomal storage disease caused by mutations in the N-acetylgalactosamine-6-sulfatase (GALNS) gene. Skeletal dysplasia and the related clinical features of MPS IVA are caused by disruption of the cartilage and its extracellular matrix, leading to a growth imbalance. Enzyme replacement therapy (ERT) with recombinant human GALNS has yielded positive results in activity of daily living and endurance tests. However, no data have demonstrated improvements in bone lesions and bone grow thin MPS IVA after ERT, and there is no correlation between therapeutic efficacy and urine levels of keratan sulfate, which accumulates in MPS IVA patients. Using qualitative and quantitative proteomics approaches, we analyzed leukocyte samples from healthy controls (n = 6) and from untreated (n = 5) and ERT-treated (n = 8, sampled before and after treatment) MPS IVA patients to identify potential biomarkers of disease. Out of 690 proteins identified in leukocytes, we selected a group of proteins that were dysregulated in MPS IVA patients with ERT. From these, we identified four potential protein biomarkers, all of which may influence bone and cartilage metabolism: lactotransferrin, coronin 1A, neutral alpha-glucosidase AB, and vitronectin. Further studies of cartilage and bone alterations in MPS IVA will be required to verify the validity of these proteins as potential biomarkers of MPS IVAS
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