Constructing the cultural repertoire in a natural disaster: The role of social media in the Thailand flood of 2011

In 2011, Thailand witnessed its worst flooding catastrophe in half a century. In this study, we explored social media as a new and promising weapon to address the physical and morale challenges caused by the natural disaster. A case study was conducted in the context of crisis response, whichinvestigated the use of social media to contribute to the collective cultural repertoire during the natural disaster. By investigating two paths toward the cultural repertoire construction considering different social groups, this study also identified the roles of social media as an information market and an information threshold in the crisis response

Classical theta constants vs. lattice theta series, and super string partition functions

Recently, various possible expressions for the vacuum-to-vacuum superstring amplitudes has been proposed at genus $g=3,4,5$. To compare the different proposals, here we will present a careful analysis of the comparison between the two main technical tools adopted to realize the proposals: the classical theta constants and the lattice theta series. We compute the relevant Fourier coefficients in order to relate the two spaces. We will prove the equivalence up to genus 4. In genus five we will show that the solutions are equivalent modulo the Schottky form and coincide if we impose the vanishing of the cosmological constant.Comment: 21 page

XMM-Newton discovery of O VII emission from warm gas in clusters of galaxies

XMM-Newton recently discovered O VII line emission from ~2 million K gas near the outer parts of several clusters of galaxies. This emission is attributed to the Warm-Hot Intergalactic Medium. The original sample of clusters studied for this purpose has been extended and two more clusters with a soft X-ray excess have been found. We discuss the physical properties of the warm gas, in particular the density, spatial extent, abundances and temperature.Comment: 8 pages, 3 figures, conference "Soft X-ray emission from clusters of galaxies and related phenomena", ed. R. Lieu, Kluwer, in pres

What does a primary care annual review for RA include? A national GP survey

Letter to the edito

Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model.

Altered neuronal excitability is emerging as an important feature in Alzheimer's disease (AD). Kv2.1 potassium channels are important modulators of neuronal excitability and synaptic activity. We investigated Kv2.1 currents and its relation to the intrinsic synaptic activity of hippocampal neurons from 3xTg-AD (triple transgenic mouse model of Alzheimer's disease) mice, a widely employed preclinical AD model. Synaptic activity was also investigated by analyzing spontaneous [Ca(2+)]i spikes. Compared with wild-type (Non-Tg (non-transgenic mouse model)) cultures, 3xTg-AD neurons showed enhanced spike frequency and decreased intensity. Compared with Non-Tg cultures, 3xTg-AD hippocampal neurons revealed reduced Kv2.1-dependent Ik current densities as well as normalized conductances. 3xTg-AD cultures also exhibited an overall decrease in the number of functional Kv2.1 channels. Immunofluorescence assay revealed an increase in Kv2.1 channel oligomerization, a condition associated with blockade of channel function. In Non-Tg neurons, pharmacological blockade of Kv2.1 channels reproduced the altered pattern found in the 3xTg-AD cultures. Moreover, compared with untreated sister cultures, pharmacological inhibition of Kv2.1 in 3xTg-AD neurons did not produce any significant modification in Ik current densities. Reactive oxygen species (ROS) promote Kv2.1 oligomerization, thereby acting as negative modulator of the channel activity. Glutamate receptor activation produced higher ROS levels in hippocampal 3xTg-AD cultures compared with Non-Tg neurons. Antioxidant treatment with N-Acetyl-Cysteine was found to rescue Kv2.1-dependent currents and decreased spontaneous hyperexcitability in 3xTg-AD neurons. Analogous results regarding spontaneous synaptic activity were observed in neuronal cultures treated with the antioxidant 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox). Our study indicates that AD-related mutations may promote enhanced ROS generation, oxidative-dependent oligomerization, and loss of function of Kv2.1 channels. These processes can be part on the increased neuronal excitability of these neurons. These steps may set a deleterious vicious circle that eventually helps to promote excitotoxic damage found in the AD brain

Canonical, squeezed and fermionic coherent states in a right quaternionic Hilbert space with a left multiplication on it

Using a left multiplication defined on a right quaternionic Hilbert space, we shall demonstrate that various classes of coherent states such as the canonical coherent states, pure squeezed states, fermionic coherent states can be defined with all the desired properties on a right quaternionic Hilbert space. Further, we shall also demonstrate squeezed states can be defined on the same Hilbert space, but the noncommutativity of quaternions prevents us in getting the desired results.Comment: Conference paper. arXiv admin note: text overlap with arXiv:1704.02946; substantial text overlap with arXiv:1706.0068

BIM and People Issues: A Scoping Study Exploring Implications for Curriculum Design

Government sponsored reports have highlighted the need for improvements in people skills for those working in the UK construction industry. The mandatory use of Building Information Modelling on government projects by 2016 (Government Construction Strategy 2011) highlight these issues and bring their own specific challenges. It is in the construction organisation’s interest that they have to innovate and adopt BIM. However evidence suggest that innovation is always met with resistance in organisations. One of the reasons for resistance is the expectation that innovation brings about the need for new skills and that some traditional skills become obsolete. The aim of this study was to get a better understanding of the ‘people’ related challenges when organisations are adopting BIM and particularly focuses on education and training requirements and the extent to which BIM implementation affects the dynamics of people skills

Large Polarization and Susceptibilities in Artificial Morphotropic Phase Boundary PbZr1−xTixO3 Superlattices

The ability to produce atomically precise, artificial oxide heterostructures allows for the possibility of producing exotic phases and enhanced susceptibilities not found in parent materials. Typical ferroelectric materials either exhibit large saturation polarization away from a phase boundary or large dielectric susceptibility near a phase boundary. Both large ferroelectric polarization and dielectric permittivity are attained wherein fully epitaxial (PbZr0.8Ti0.2O3)n/(PbZr0.4Ti0.6O3)2n (n = 2, 4, 6, 8, 16 unit cells) superlattices are produced such that the overall film chemistry is at the morphotropic phase boundary, but constitutive layers are not. Long- (n ≥ 6) and short-period (n = 2) superlattices reveal large ferroelectric saturation polarization (Ps = 64 µC cm−2) and small dielectric permittivity (εr ≈ 400 at 10 kHz). Intermediate-period (n = 4) superlattices, however, exhibit both large ferroelectric saturation polarization (Ps = 64 µC cm−2) and dielectric permittivity (εr = 776 at 10 kHz). First-order reversal curve analysis reveals the presence of switching distributions for each parent layer and a third, interfacial layer wherein superlattice periodicity modulates the volume fraction of each switching distribution and thus the overall material response. This reveals that deterministic creation of artificial superlattices is an effective pathway for designing materials with enhanced responses to applied bias