9,774 research outputs found

    Goldstone Superfield Actions in AdS5 backgrounds

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    Nonlinear realizations superfield techniques, pertinent to the description of partial breaking of global N=2 supersymmetry in a flat d=4 super Minkowski background, are generalized to the case of partially broken N=1 AdS5 supersymmetry SU(2,2|1). We present, in an explicit form, off-shell manifestly N=1, d=4 supersymmetric minimal Goldstone superfield actions for two patterns of partial breaking of SU(2,2|1) supersymmetry. They correspond to two different nonlinear realizations of the latter, in the supercosets with the AdS5 and AdS5\times S1 bosonic parts. The relevant worldvolume Goldstone supermultiplets are accommodated, respectively, by improved tensor and chiral N=1, d=4 superfields. The second action is obtained from the first one by dualizing the improved tensor Goldstone multiplet into a chiral Goldstone one. In the bosonic sectors, the first and second actions yield static-gauge Nambu-Goto actions for a L3-brane on AdS5 and a scalar 3-brane on AdS5\times S1.Comment: 20 pages, LaTeX, no figures, published versio

    Antibodies against the cardiac sodium/bicarbonate co-transporter (NBCe1) as pharmacological tools

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    Background and purpose: Na⁺/HCO3⁻ co-transport (NBC) regulates intracellular pH (pHi) in the heart. We have studied the electrogenic NBC isoform NBCe1 by examining the effect of functional antibodies to this protein. Experimental approach: We generated two antibodies against putative extracellular loop domains 3 (a-L3) and 4 (a-L4) of NBCe1 which recognized NBCe1 on immunoblots and immunostaining experiments. pHi was monitored using epi-fluorescence measurements in cat ventricular myocytes. Transport activity of total NBC and of NBCe1 in isolation were evaluated after an ammonium ion-induced acidosis (expressed as H⁺ flux, JH, in mmol·L-1 min-1 at pHi 6.8) and during membrane depolarization with high extracellular potassium (potassium pulse, expressed as ΔpHi) respectively. Key results: The potassium pulse produced a pHi increase of 0.18 ± 0.006 (n= 5), which was reduced by the a-L3 antibody (0.016 ± 0.019). The a-L-3 also decreased JH by 50%. Surprisingly, during the potassium pulse, a-L4 induced a higher pHi increase than control,(0.25 ± 0.018) whereas the recovery of pHi from acidosis was faster (JH was almost double the control value). In perforated-patch experiments, a-L3 prolonged and a-L4 shortened action potential duration, consistent with blockade and stimulation of NBCe1-carried anionic current respectively. Conclusions and implications: Both antibodies recognized NBCe1, but they had opposing effects on the function of this transporter, as the a-L3 was inhibitory and the a-L4 was excitatory. These antibodies could be valuable in studies on the pathophysiology of NBCe1 in cardiac tissue, opening a path for their potential clinical use.Facultad de Ciencias MédicasCentro de Investigaciones Cardiovasculare

    Benefits bilingual children should have when learning English as a Third language

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    Treball Final de Grau en Mestre o Mestra d'Educació Infantil. Codi: MI1040. Curs acadèmic: 2016-2017.The use of English as a lingua franca in Europe has increased the importance of language learning processes in modern education. Since an early age, English is introduced in the educational programmes. This research is focused in Betxí, a town from the Valencian Community, and a bilingual area where Valencian and Spanish are used daily. Since pre-school, children from this place have a plurilingual education, because they learn Valencian and Spanish as their mother tongues, plus English as a Third Language (L3). Some European research has demonstrated that being bilingual has some benefits over being monolingual when acquiring English as a L3. Thus, the main point of this research is to establish the benefits bilingual children from Betxí should have when acquiring English as a L3. However, this research deals with the following hypothesis: Did previous research really prove the benefits bilinguals should have when learning a L3? In this particular bilingual area, Valencian should be promoted, as well as every minority language in Europe. This study wants to show the benefits bilinguals have for promoting the use of minority languages in those bilingual places where other languages, such as Spanish in this case, play a primary role in society

    PHOENIX model chromospheres of mid- to late-type M dwarfs

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    We present semi-empirical model chromospheres computed with the atmosphere code PHOENIX. The models are designed to fit the observed spectra of five mid- to late-type M dwarfs. Next to hydrogen lines from the Balmer series we used various metal lines, e. g. from Fe {\sc i}, for the comparison between data and models. Our computations show that an NLTE treatment of C, N, O impacts on the hydrogen line formation, while NLTE treatment of less abundant metals such as nickel influences the lines of the considered species itself. For our coolest models we investigated also the influence of dust on the chromospheres and found that dust increases the emission line flux. Moreover we present an (electronically published) emission line list for the spectral range of 3100 to 3900 and 4700 to 6800 \AA for a set of 21 M dwarfs and brown dwarfs. The line list includes the detection of the Na {\sc i} D lines in emission for a L3 dwarf.Comment: 14 pages, 18 figure
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