Myocardial Involvement After Hospitalization for COVID-19 Complicated by Troponin Elevation : A Prospective, Multicenter, Observational Study

Dr Berry acknowledges British Heart Foundation support (grant RE/18/6134217). Dr Artico received funding from the European Association of Cardiovascular Imaging (EACVI research grant App000073878). Dr McCann is funded by an NIHR research professorship (RP-2017-08-ST2-007). Dr Manisty is funded by an NIHR clinician scientist award (CS-2015-15-003). Drs Ferreira, Piechnik, and Neubauer thank the NIHR Oxford Biomedical Research Centre for support of this study. Dr Bucciarelli-Ducci is supported in part by the NIHR Biomedical Research Centre at University Hospitals Bristol National Health Service Foundation Trust and the University of Bristol. Additional support was provided by the NIHR Leicester Biomedical Research Centre and the NIHR Leeds Clinical Research Facility. Dr Dweck is supported by the British Heart Foundation (grant FS/SCRF/21/32010). The authors thank the patients and staff who supported this project. Supported by NIHR and UK Research and Innovation (COV0254). West Yorkshire and Humber Clinical Research Network (CV070) funded patient information leaflet translation.Peer reviewedPublisher PD

Serum lipid profiles in acute myocardial infarction patients in Gorgan

Acute myocardial infarction is one of the important reasons of death and unhealthiness in the world. The present study was undertaken to investigate the changes in serum lipids and lipoproteins in patients with acute myocardial infarction. This study was performed in the Biochemistry and Metabolic Disorder Research Center of Gorgan, Golestan province (South East of Caspian Sea), Iran in 2011.The levels of lipid profile were significantly changed in the acute myocardial infarction patients. acute myocardial infarction patients had significantly higher levels of total cholesterol, LDL-cholesterol, VLDL-cholesterol, TG, LDLcholesterol /HDL-cholesterol, total cholesterol /HDL-cholesterol, LDH, CPK and CPK-MB and lower level of HDL-cholesterol, as compared to the control subjects. We found a significant association of lipid profiles with acute myocardial infarction. Changing of dietary and social activity habits of people in this area can help to prevent future atherogenic damaging in AMI patients. Copyright © 2012, Scientific Publisher of India

Decision making processes in people with symptoms of acute myocardial infarction: qualitative study

Objective To identify, the themes that influence decision making processes used by patients with symptoms of acute myocardial infarction. Design Qualitative study using semistructured interviews. Setting Two district hospitals in North Yorkshire. Participants 22 patients admitted to hospital with confirmed second, third, or fourth acute myocardial infarction. Main outcome measure Patients' perceptions of their experience between the onset of symptoms and the decision to seek medical help. Results Six main themes that influence the decision making process were identified: appraisal of In symptoms, perceived risk, previous experience, psychological and emotional factors, use of the NHS, and context of the event. Conclusions Knowledge of symptoms may not be enough to promote prompt action in the event of an acute myocardial infarction. Cognitive and emotional processes, individual beliefs and values, and the influence of the context of the event should also be considered in individual interventions designed to reduce delay in the event of symptoms of acute myocardial infarction

To study the organization of LDL-C/HDL-C ratio and inflammatory marker CRP in acute myocardial infarction

There is an increasing incidence of coronary artery disease in India. We therefore need a tool to evaluate the severity and prognosis of this acute myocardial infarction. In acute myocardial infarction, the function of plaque rupture and inflammation has already been identified. Aim: To study the organization of LDL-C/HDL-C ratio and inflammatory marker CRP in acute myocardial infarction. Methods and Material: Patients who have been diagnosed as acute myocardial infarction (ST Elevation Acute myocardial Infarction or Unstable angina/Non ST Elevation Myocardial Infarction) and admitted to ICCU of Rajiv Gandhi institute of Medical Sciences, Kadapa, AP. are the subjects. Sample consists of 100 cases of acute myocardial infarction. Case history was taken from the patients, and studied according to proforma. Conclusion: Elevated levels of CRP are independent indicators of adverse effects. When contrast with the LDL / HDL ratio, CRP is used for risk stratification and as a prognostic predictor. These findings suggest that in patients with acute myocardial infarction, raised CRP Levels is significant as compared to LDL/HDL ratio

Effectiveness of implementation of standard clinical pathway through healthcare professionals among acute myocardial infarction patients undergoing angiography / angioplasty in a public tertiary care hospital, Karachi

Objective: To assess the effect of acute myocardial infarction standard clinical pathway among acute myocardial infarction patients on length of stay in public tertiary care setting.Methods: The quasi-experimental non-randomised study was conducted at the Department of Cardiology, Dr Ruth Pfau Civil Hospital, Karachi, from September to December 2018, and comprised acute myocardial infarction patients. Those admitted before the implementation of acute myocardial infarction standard clinical pathway formed the control group, while those admitted after the implementation were in the intervention group. Acute myocardial infarction standard clinical pathway was implemented and the interventional clinical practices of healthcare professionals, including cardiologists, postgraduates, residents, nurses and critical care technicians, were assessed using a standard checklist. Data was analysed using SPSS 21.Results: Of the 100 participants, 50(50%) were in the control group; 31(62%) males and 19(38%) females. The intervention group also had 50(50%) patients; 35(70%) males and 15(30%) females. Regarding effectiveness of the implementation of standard clinical pathway, length of hospital stay reduced significantly in the intervention group compared to the control group (p=0.003).Conclusions: The implementation of acute myocardial infarction standard clinical pathway reduced the length of hospital stay of acute myocardial infarction patients

Changes of Acylating Stimulating Protein (ASP) and Blood Lipid in Patients with Acute Myocardial Infarction

Objective: To study the changes of acylating stimulating protein (ASP) and blood lipid in patients with acute myocardial infarction. Method: There were three groups,25 cases of acute myocardial infarction patients (acute myocardial infarction group), 32 cases of coronary heart disease patients without myocardial infarction (CHD group) and 30 cases of healthy people (control group). They respectively detected the ASP, low density lipoprotein cholesterol (LDL-C), triglyceride (TG), total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C), and analyzed the correlation between them. Results: (1) ASP, TG, TC and LDL-C of acute myocardial infarction group and coronary heart disease group were significantly higher than those of control group, while HDL-C was lower than control group, the difference was statistically significant (P < 0.05). (2) TG in coronary heart disease group was higher than that in acute myocardial infarction group, while ASP, TC, LDL-C and HDL-C had no significant difference. Conclusion: ASP and blood lipid are risk factors of CHD, ASP can be used as risk index of CHD. There was no significant difference in plasma ASP between patients with acute myocardial infarction and patients with coronary heart disease without myocardial infarction. ASP cannot be used as a surrogate marker of acute myocardial infarction

Serum Glutamic Oxalacetic Transaminase Assay in the Diagnosis of Acute Myocardial Infarction

The assay of serum transaminase, by the spectrophotometric method, is accurate, reproducible and suitable for research purposes. The enzyme is of such stability as to facilitate its clinical usefulness. Only specimens of serum, without evidence of haemolysis should be used for the test. Normal, borderline and high levels of serum transaminase activity have been arbitrarily defined. High levels of serum transaminase activity were demonstrated following 84% of attacks of acute myocardial infarction. The importance of performing the assay 6-24 and 24-48 hours after the onset of acute myocardial infarction is emphasised since, in 14.5% of attacks, too early or too late sampling of the serum accounted for the failure to demonstrate high levels of serum transaminase activity. In those attacks of acute myocardial infarction in which the assay was performed at the recommended times, high levels of serum transaminase activity were detected in 98.2%. There was no evidence that the rise of serum transaminase activity following acute myocardial infarction was due to damage to the liver. Evidence has been presented which suggests that there is a statistical correlation between the level of serum transaminase activity and the degree of peripheral vascular failure developing after acute myocardial Infarction, although serum transaminase activity cannot be used as an index of the degree of peripheral vascular failure in the individual case. High levels of serum transaminase activity are rot found in myocardial ischaemia, although an increase of activity to borderline levels may be demonstrated. Increased serum transaminase activity may be detected in lesions other than acute myocardial infarction. High levels of serum transaminase activity were demonstrated in diseases of the liver, but this matters less than the detection of increased serum transaminase activity in conditions which may be confused with, or complicate, acute myocardial infarction e.g., in dissecting aneurysm of the aorta, acute pulmonary infarction, acute pancreatitis, chronic cholecystitis, arterial embolism and thrombosis and in rapid cardiac arrhythmias. The probable sources of increased serum transaminase activity in conditions other than acute myocardial infarction have been discussed. In differentiating between acute myocardial infarction and other diseases, the demonstration of normal serum transaminase activity at the recommended times after the onset of illness Is supporting evidence against the diagnosis of acute myocardial infarction. Serum transaminase assay cannot replace the electrocardiogram in the diagnosis of acute myocardial infarction. It is a diagnostic aid rather than a substitute for any of the existing diagnostic procedures, although it has been shown to be superior to pyrexia and the ESR, as an index of acute myocardial infarction in the early stages of the illness. (Abstract shortened by ProQuest.)

Evaluasi Drug Related Problems (Drps) Pada Pengobatan Pasien Infark Miokard Akut (Ima) Di Intensive Care Unit Rumah Sakit Umum Daerah Banyumas Periode Agustus 2009-juni 2010

Acute myocardial infarction is a primer major health problem which needs special attention because of the mortality prevalence and the cost is quite high, at around 1.5 million Americans who suffer from Acute Myocardial Infarction per year with a mortality rate is 30%, while in Indonesia, deaths caused by Coronary heart disease is estimated 53.5% per 100 000 population. The patients of Acute Myocardial Infarction always complaint their chest pain like a pinched, punched, burned and the intensity is mild or long duration. Treatment of Acute Myocardial Infarction in patients needs mahy varieties medicine so it can enlarge the possibility of Drug Related Problems (DRPs). This study aimed to investigate the DRPs that occur in the in the Acute Myocardial Infarction treatment who get special treatment in the Intensive Care Unit, RSU Banyumas in the period August 2009 - June 2010. DRPs indications included medication necessary medicine, unnecessary medicine wrong medicine, inadequate dosage, over dosage, and drug interactions. This research is included research descriptive with retrospective design. The results of 16 cases shows that DRPs occur in necessary medicine is 31.3%, unnecessary medicine is 6.3%, inadequate dosage is not be found, over dosage is 12.5%, and medicine interaction is 100%. Based on the results can be concluded that there are many medicines those are needed in the Acute Myocardial Infarction in intensive care. Keywords: Acute Myocardial Infarction (AMI), DRPs, necessary medication, unnecessary medications, over dosages

Gender differences in hospital mortality and use of percutaneous coronary intervention in acute myocardial infarction : microsimulation analysis of the 1999 nationwide french hospitals database.

Background— Women with acute myocardial infarction have a higher hospital mortality rate than men. This difference has been ascribed to their older age, more frequent comorbidities, and less frequent use of revascularization. The aim of this study is to assess these factors in relation to excess mortality in women. Methods and Results— All hospital admissions in France with a discharge diagnosis of acute myocardial infarction were extracted from the national payment database. Logistic regression on mortality was performed for age, comorbidities, and coronary interventions. Nonparametric microsimulation models estimated the percutaneous coronary intervention and mortality rates that women would experience if they were "treated like men." Data were analyzed from 74 389 patients hospitalized with acute myocardial infarction, 30.0% of whom were women. Women were older (75 versus 63 years of age; Pacute myocardial infarction gender; revascularization; mortality;