18 research outputs found

    Planning for steerable needles in neurosurgery

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    The increasing adoption of robotic-assisted surgery has opened up the possibility to control innovative dexterous tools to improve patient outcomes in a minimally invasive way. Steerable needles belong to this category, and their potential has been recognised in various surgical fields, including neurosurgery. However, planning for steerable catheters' insertions might appear counterintuitive even for expert clinicians. Strategies and tools to aid the surgeon in selecting a feasible trajectory to follow and methods to assist them intra-operatively during the insertion process are currently of great interest as they could accelerate steerable needles' translation from research to practical use. However, existing computer-assisted planning (CAP) algorithms are often limited in their ability to meet both operational and kinematic constraints in the context of precise neurosurgery, due to its demanding surgical conditions and highly complex environment. The research contributions in this thesis relate to understanding the existing gap in planning curved insertions for steerable needles and implementing intelligent CAP techniques to use in the context of neurosurgery. Among this thesis contributions showcase (i) the development of a pre-operative CAP for precise neurosurgery applications able to generate optimised paths at a safe distance from brain sensitive structures while meeting steerable needles kinematic constraints; (ii) the development of an intra-operative CAP able to adjust the current insertion path with high stability while compensating for online tissue deformation; (iii) the integration of both methods into a commercial user front-end interface (NeuroInspire, Renishaw plc.) tested during a series of user-controlled needle steering animal trials, demonstrating successful targeting performances. (iv) investigating the use of steerable needles in the context of laser interstitial thermal therapy (LiTT) for maesial temporal lobe epilepsy patients and proposing the first LiTT CAP for steerable needles within this context. The thesis concludes with a discussion of these contributions and suggestions for future work.Open Acces

    Full 3D motion control for programmable bevel-tip steerable needles

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    Minimally invasive surgery has been in the focus of many researchers due to its reduced intra- and post-operative risks when compared to an equivalent open surgery approach. In the context of minimally invasive surgery, percutaneous intervention, and particularly, needle insertions, are of great importance in tumour-related therapy and diagnosis. However, needle and tissue deformation occurring during needle insertion often results in misplacement of the needles, which leads to complications, such as unsuccessful treatment and misdiagnosis. To this end, steerable needles have been proposed to compensate for placement errors by allowing curvilinear navigation. A particular type of steerable needle is the programmable bevel-tip steerable needle (PBN), which is a bio-inspired needle that consists of relatively soft and slender segments. Due to its flexibility and bevel-tip segments, it can navigate through 3D curvilinear paths. In PBNs, steering in a desired direction is performed by actuating particular PBN segments. Therefore, the pose of each segment is needed to ensure that the correct segment is actuated. To this end, in this thesis, proprioceptive sensing methods for PBNs were investigated. Two novel methods, an electromagnetic (EM)-based tip pose estimation method and a fibre Bragg grating (FBG)-based full shape sensing method, were presented and evaluated. The error in position was observed to be less than 1.08 mm and 5.76 mm, with the proposed EM-based tip tracking and FBG-based shape reconstruction methods, respectively. Moreover, autonomous path-following controllers for PBNs were also investigated. A closed-loop, 3D path-following controller, which was closed via feedback from FBG-inscribed multi-core fibres embedded within the needle, was presented. The nonlinear guidance law, which is a well-known approach for path-following control of aerial vehicles, and active disturbance rejection control (ADRC), which is known for its robustness within hard-to-model environments, were chosen as the control methods. Both linear and nonlinear ADRC were investigated, and the approaches were validated in both ex vivo brain and phantom tissue, with some of the experiments involving moving targets. The tracking error in position was observed to be less than 6.56 mm.Open Acces

    Medical Robotics

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    The first generation of surgical robots are already being installed in a number of operating rooms around the world. Robotics is being introduced to medicine because it allows for unprecedented control and precision of surgical instruments in minimally invasive procedures. So far, robots have been used to position an endoscope, perform gallbladder surgery and correct gastroesophogeal reflux and heartburn. The ultimate goal of the robotic surgery field is to design a robot that can be used to perform closed-chest, beating-heart surgery. The use of robotics in surgery will expand over the next decades without any doubt. Minimally Invasive Surgery (MIS) is a revolutionary approach in surgery. In MIS, the operation is performed with instruments and viewing equipment inserted into the body through small incisions created by the surgeon, in contrast to open surgery with large incisions. This minimizes surgical trauma and damage to healthy tissue, resulting in shorter patient recovery time. The aim of this book is to provide an overview of the state-of-art, to present new ideas, original results and practical experiences in this expanding area. Nevertheless, many chapters in the book concern advanced research on this growing area. The book provides critical analysis of clinical trials, assessment of the benefits and risks of the application of these technologies. This book is certainly a small sample of the research activity on Medical Robotics going on around the globe as you read it, but it surely covers a good deal of what has been done in the field recently, and as such it works as a valuable source for researchers interested in the involved subjects, whether they are currently “medical roboticists” or not

    Exploring the use of routine healthcare data through process mining to inform the management of musculoskeletal diseases

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    Healthcare informatics can help address some of the challenges faced by both healthcare providers and patients. The medical domain is characterised by inherently complex and intricate issues, data can often be of poor quality and novel techniques are required. Process mining is a discipline that uses techniques to extract insights from event data, generated during the execution of processes. It has had good results in various branches of medical science but applications to musculoskeletal diseases remain largely unexplored. This research commenced with a review of the healthcare and technical literature and applied a variety of process mining techniques in order to investigate approaches to the healthcare plans of patients with musculoskeletal conditions. The analysis involved three datasets from: 1) a private hospital in Boston, US, where data was used to create disease trajectory models. Results suggest the method may be of interest to healthcare researchers, as it enables a more rapid modelling and visualisation; 2) a mobile healthcare application for patients receiving physiotherapy in Sheffield, UK, where data was used to identify possible indicators for health outcomes. After evaluation of the results, it was found that the indicators identified may be down to chance; and 3) the population of Wales to explore knee pain surgery pathways. Results suggest that process mining is an effective technique. This work demonstrates how routine healthcare data can be analysed using process mining techniques to provide insights that may benefit patients suffering with musculoskeletal conditions. This thesis explores how strict criteria for analysis can be performed. The work is intended to expand the breadth of process mining methods available to the data science community and has contributed by making recommendations for service utilisation within physiotherapy at Sheffield Hospital and helped to define a roadmap for a leading healthcare software company

    Safety and Reliability - Safe Societies in a Changing World

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    The contributions cover a wide range of methodologies and application areas for safety and reliability that contribute to safe societies in a changing world. These methodologies and applications include: - foundations of risk and reliability assessment and management - mathematical methods in reliability and safety - risk assessment - risk management - system reliability - uncertainty analysis - digitalization and big data - prognostics and system health management - occupational safety - accident and incident modeling - maintenance modeling and applications - simulation for safety and reliability analysis - dynamic risk and barrier management - organizational factors and safety culture - human factors and human reliability - resilience engineering - structural reliability - natural hazards - security - economic analysis in risk managemen

    Front-Line Physicians' Satisfaction with Information Systems in Hospitals

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    Day-to-day operations management in hospital units is difficult due to continuously varying situations, several actors involved and a vast number of information systems in use. The aim of this study was to describe front-line physicians' satisfaction with existing information systems needed to support the day-to-day operations management in hospitals. A cross-sectional survey was used and data chosen with stratified random sampling were collected in nine hospitals. Data were analyzed with descriptive and inferential statistical methods. The response rate was 65 % (n = 111). The physicians reported that information systems support their decision making to some extent, but they do not improve access to information nor are they tailored for physicians. The respondents also reported that they need to use several information systems to support decision making and that they would prefer one information system to access important information. Improved information access would better support physicians' decision making and has the potential to improve the quality of decisions and speed up the decision making process.Peer reviewe

    Safe Haptics-enabled Patient-Robot Interaction for Robotic and Telerobotic Rehabilitation of Neuromuscular Disorders: Control Design and Analysis

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    Motivation: Current statistics show that the population of seniors and the incidence rate of age-related neuromuscular disorders are rapidly increasing worldwide. Improving medical care is likely to increase the survival rate but will result in even more patients in need of Assistive, Rehabilitation and Assessment (ARA) services for extended periods which will place a significant burden on the world\u27s healthcare systems. In many cases, the only alternative is limited and often delayed outpatient therapy. The situation will be worse for patients in remote areas. One potential solution is to develop technologies that provide efficient and safe means of in-hospital and in-home kinesthetic rehabilitation. In this regard, Haptics-enabled Interactive Robotic Neurorehabilitation (HIRN) systems have been developed. Existing Challenges: Although there are specific advantages with the use of HIRN technologies, there still exist several technical and control challenges, e.g., (a) absence of direct interactive physical interaction between therapists and patients; (b) questionable adaptability and flexibility considering the sensorimotor needs of patients; (c) limited accessibility in remote areas; and (d) guaranteeing patient-robot interaction safety while maximizing system transparency, especially when high control effort is needed for severely disabled patients, when the robot is to be used in a patient\u27s home or when the patient experiences involuntary movements. These challenges have provided the motivation for this research. Research Statement: In this project, a novel haptics-enabled telerobotic rehabilitation framework is designed, analyzed and implemented that can be used as a new paradigm for delivering motor therapy which gives therapists direct kinesthetic supervision over the robotic rehabilitation procedure. The system also allows for kinesthetic remote and ultimately in-home rehabilitation. To guarantee interaction safety while maximizing the performance of the system, a new framework for designing stabilizing controllers is developed initially based on small-gain theory and then completed using strong passivity theory. The proposed control framework takes into account knowledge about the variable biomechanical capabilities of the patient\u27s limb(s) in absorbing interaction forces and mechanical energy. The technique is generalized for use for classical rehabilitation robotic systems to realize patient-robot interaction safety while enhancing performance. In the next step, the proposed telerobotic system is studied as a modality of training for classical HIRN systems. The goal is to first model and then regenerate the prescribed kinesthetic supervision of an expert therapist. To broaden the population of patients who can use the technology and HIRN systems, a new control strategy is designed for patients experiencing involuntary movements. As the last step, the outcomes of the proposed theoretical and technological developments are translated to designing assistive mechatronic tools for patients with force and motion control deficits. This study shows that proper augmentation of haptic inputs can not only enhance the transparency and safety of robotic and telerobotic rehabilitation systems, but it can also assist patients with force and motion control deficiencies
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