Implementation of workflow engine technology to deliver basic clinical decision support functionality

BACKGROUND: Workflow engine technology represents a new class of software with the ability to graphically model step-based knowledge. We present application of this novel technology to the domain of clinical decision support. Successful implementation of decision support within an electronic health record (EHR) remains an unsolved research challenge. Previous research efforts were mostly based on healthcare-specific representation standards and execution engines and did not reach wide adoption. We focus on two challenges in decision support systems: the ability to test decision logic on retrospective data prior prospective deployment and the challenge of user-friendly representation of clinical logic. RESULTS: We present our implementation of a workflow engine technology that addresses the two above-described challenges in delivering clinical decision support. Our system is based on a cross-industry standard of XML (extensible markup language) process definition language (XPDL). The core components of the system are a workflow editor for modeling clinical scenarios and a workflow engine for execution of those scenarios. We demonstrate, with an open-source and publicly available workflow suite, that clinical decision support logic can be executed on retrospective data. The same flowchart-based representation can also function in a prospective mode where the system can be integrated with an EHR system and respond to real-time clinical events. We limit the scope of our implementation to decision support content generation (which can be EHR system vendor independent). We do not focus on supporting complex decision support content delivery mechanisms due to lack of standardization of EHR systems in this area. We present results of our evaluation of the flowchart-based graphical notation as well as architectural evaluation of our implementation using an established evaluation framework for clinical decision support architecture. CONCLUSIONS: We describe an implementation of a free workflow technology software suite (available at http://code.google.com/p/healthflow) and its application in the domain of clinical decision support. Our implementation seamlessly supports clinical logic testing on retrospective data and offers a user-friendly knowledge representation paradigm. With the presented software implementation, we demonstrate that workflow engine technology can provide a decision support platform which evaluates well against an established clinical decision support architecture evaluation framework. Due to cross-industry usage of workflow engine technology, we can expect significant future functionality enhancements that will further improve the technology's capacity to serve as a clinical decision support platform

A Semantic Framework for Declarative and Procedural Knowledge

In any scientic domain, the full set of data and programs has reached an-ome status, i.e. it has grown massively. The original article on the Semantic Web describes the evolution of a Web of actionable information, i.e.\ud information derived from data through a semantic theory for interpreting the symbols. In a Semantic Web, methodologies are studied for describing, managing and analyzing both resources (domain knowledge) and applications (operational knowledge) - without any restriction on what and where they\ud are respectively suitable and available in the Web - as well as for realizing automatic and semantic-driven work\ud ows of Web applications elaborating Web resources.\ud This thesis attempts to provide a synthesis among Semantic Web technologies, Ontology Research, Knowledge and Work\ud ow Management. Such a synthesis is represented by Resourceome, a Web-based framework consisting of two components which strictly interact with each other: an ontology-based and domain-independent knowledge manager system (Resourceome KMS) - relying on a knowledge model where resource and operational knowledge are contextualized in any domain - and a semantic-driven work ow editor, manager and agent-based execution system (Resourceome WMS).\ud The Resourceome KMS and the Resourceome WMS are exploited in order to realize semantic-driven formulations of work\ud ows, where activities are semantically linked to any involved resource. In the whole, combining the use of domain ontologies and work ow techniques, Resourceome provides a exible domain and operational knowledge organization, a powerful engine for semantic-driven work\ud ow composition, and a distributed, automatic and\ud transparent environment for work ow execution

A Design Environment for Product Knowledge Management and Data Exchange

This paper reports on a distributed design environment under development for product knowledge management and information exchange. The system is able to use the company’s existing base of knowledge and to push the manufacturing knowledge higher up into the design chain to reduce the need for costly and time consuming reworks and engineering changes. The design environment uses a knowledge based system Protégé and enables data/knowledge exchange through International Standards for Product Model Exchange (ISO STEP) and the Resource Description Framework

From BPMN Models to Labelled Property Graphs

There\u27s a growing interest in leveraging the structured and formal nature of business process modeling languages in order to make them available not only for human analysis but also to machine-readable knowledge representation. Standard serializations of the past were predominantly XML based, with some of them seemingly discontinued, e.g., XPDL after the dissolution of the Workflow Management Coalition. Recent research has been investigating the interplay between knowledge representation and business process modeling, with the focus typically placed on standards such as RDF and OWL. In this paper we introduce a converter that translates the standards-compliant BPMN XML format to Neo4J labelled property graphs (LPG) thus providing an alternative to both traditional XML-based serialization and to more recent experimental RDF solutions, while ensuring conceptual alignment with the standard serialization of BPMN 2.0. A demonstrator was built to highlight the benefits of having such a parser and the completeness of coverage for BPMN models. The proposal facilitates graph-based processing of business process models in a knowledge intensive context, where procedural knowledge available as BPMN diagrams must be exposed to machines and LPG-driven applications

Compliance flow: an intelligent workflow management system to support engineering processes

This work is about extending the scope of current workflow management systems to support engineering processes. On the one hand engineering processes are relatively dynamic, and on the other their specification and performance are constrained by industry standards and guidelines for the sake of product acceptability, such as IEC 61508 for safety and ISO 9001 for quality. A number of technologies have been proposed to increase the adaptability of current workflow systems to deal with dynamic situations. A primary concern is how to support open-ended processes that cannot be completely specified in detail prior to their execution. A survey of adaptive workflow systems is given and the enabling technologies are discussed. Engineering processes are studied and their characteristics are identified and discussed. Current workflow systems have been successfully used in managing "administrative" processes for some time, but they lack the flexibility to support dynamic, unpredictable, collaborative, and highly interdependent engineering processes. [Continues.

Web Engineering for Workflow-based Applications: Models, Systems and Methodologies

This dissertation presents novel solutions for the construction of Workflow-based Web applications: The Web Engineering DSL Framework, a stakeholder-oriented Web Engineering methodology based on Domain-Specific Languages; the Workflow DSL for the efficient engineering of Web-based Workflows with strong stakeholder involvement; the Dialog DSL for the usability-oriented development of advanced Web-based dialogs; the Web Engineering Reuse Sphere enabling holistic, stakeholder-oriented reuse

Ontology mapping of business process modeling based on formal temporal logic

A business process is the combination of a set of activities with logical order and dependence, whose objective is to produce a desired goal. Business process modeling (BPM) using knowledge of the available process modeling techniques enable a common understanding and analysis of a business process. Industry and academics use informal and formal methods respectively to represent business processes (BP), having the main objective to support an organization. Despite both are aiming at BPM but the methods used are quite different in their semantics. While carrying out literature research, it has been found that there is no general representation of business process modeling is available that is expressive than the commercial modeling tools and techniques. Therefore, it is primarily conceived to provide an ontology mapping of modeling terms of Business Process Modeling Notation (BPMN), Unified Modeling Language (UML) Activity Diagrams (AD) and Event Driven Process Chains (EPC) to temporal logic. Being a formal system, first order logic assists in thorough understanding of process modeling and its application. However, our contribution is to devise a versatile conceptual categorization of modeling terms/constructs and also formalizing them, based on well accepted business notions, such as action, event, process, sub-process, connector and flow. It is demonstrated that the new categorization of modeling terms mapped to formal temporal logic, provides the expressive power to subsume business process modeling techniques i.e. BPMN, UML AD and EPC

A novel workflow management system for handling dynamic process adaptation and compliance

Modern enterprise organisations rely on dynamic processes. Generally these processes cannot be modelled once and executed repeatedly without change. Enterprise processes may evolve unpredictably according to situations that cannot always be prescribed. However, no mechanism exists to ensure an updated process does not violate any compliance requirements. Typical workflow processes may follow a process definition and execute several thousand instances using a workflow engine without any changes. This is suitable for routine business processes. However, when business processes need flexibility, adaptive features are needed. Updating processes may violate compliance requirements so automatic verification of compliance checking is necessary. The research work presented in this Thesis investigates the problem of current workflow technology in defining, managing and ensuring the specification and execution of business processes that are dynamic in nature, combined with policy standards throughout the process lifycle. The findings from the literature review and the system requirements are used to design the proposed system architecture. Since a two-tier reference process model is not sufficient as a basis for the reference model for an adaptive and compliance workflow management system, a three-tier process model is proposed. The major components of the architecture consist of process models, business rules and plugin modules. This architecture exhibits the concept of user adaptation with structural checks and dynamic adaptation with data-driven checks. A research prototype - Adaptive and Compliance Workflow Management System (ACWfMS) - was developed based on the proposed system architecture to implement core services of the system for testing and evaluation purposes. The ACWfMS enables the development of a workflow management tool to create or update the process models. It automatically validates compliance requirements and, in the case of violations, visual feedback is presented to the user. In addition, the architecture facilitates process migration to manage specific instances with modified definitions. A case study based on the postgraduate research process domain is discussed