209,916 research outputs found
Digital Ecosystems: Ecosystem-Oriented Architectures
We view Digital Ecosystems to be the digital counterparts of biological
ecosystems. Here, we are concerned with the creation of these Digital
Ecosystems, exploiting the self-organising properties of biological ecosystems
to evolve high-level software applications. Therefore, we created the Digital
Ecosystem, a novel optimisation technique inspired by biological ecosystems,
where the optimisation works at two levels: a first optimisation, migration of
agents which are distributed in a decentralised peer-to-peer network, operating
continuously in time; this process feeds a second optimisation based on
evolutionary computing that operates locally on single peers and is aimed at
finding solutions to satisfy locally relevant constraints. The Digital
Ecosystem was then measured experimentally through simulations, with measures
originating from theoretical ecology, evaluating its likeness to biological
ecosystems. This included its responsiveness to requests for applications from
the user base, as a measure of the ecological succession (ecosystem maturity).
Overall, we have advanced the understanding of Digital Ecosystems, creating
Ecosystem-Oriented Architectures where the word ecosystem is more than just a
metaphor.Comment: 39 pages, 26 figures, journa
Community standards for open cell migration data
Cell migration research has become a high-content field. However, the quantitative information encapsulated in these complex and high-dimensional datasets is not fully exploited owing to the diversity of experimental protocols and non-standardized output formats. In addition, typically the datasets are not open for reuse. Making the data open and Findable, Accessible, Interoperable, and Reusable (FAIR) will enable meta-analysis, data integration, and data mining. Standardized data formats and controlled vocabularies are essential for building a suitable infrastructure for that purpose but are not available in the cell migration domain. We here present standardization efforts by the Cell Migration Standardisation Organisation (CMSO), an open community-driven organization to facilitate the development of standards for cell migration data. This work will foster the development of improved algorithms and tools and enable secondary analysis of public datasets, ultimately unlocking new knowledge of the complex biological process of cell migration
Digital Preservation Services : State of the Art Analysis
Research report funded by the DC-NET project.An overview of the state of the art in service provision for digital preservation and curation. Its focus is on the areas where bridging the gaps is needed between e-Infrastructures and efficient and forward-looking digital preservation services. Based on a desktop study and a rapid analysis of some 190 currently available tools and services for digital preservation, the deliverable provides a high-level view on the range of instruments currently on offer to support various functions within a preservation system.European Commission, FP7peer-reviewe
Cloud Storage and Bioinformatics in a private cloud deployment: Lessons for Data Intensive research
This paper describes service portability for a private cloud deployment, including a detailed case study about Cloud Storage and bioinformatics services developed as part of the Cloud Computing Adoption Framework (CCAF). Our Cloud Storage design and deployment is based on Storage Area Network (SAN) technologies, details of which include functionalities, technical implementation, architecture and user support. Experiments for data services (backup automation, data recovery and data migration) are performed and results confirm backup automation is completed swiftly and is reliable for data-intensive research. The data recovery result confirms that execution time is in proportion to quantity of recovered data, but the failure rate increases in an exponential manner. The data migration result confirms execution time is in proportion to disk volume of migrated data, but again the failure rate increases in an exponential manner. In addition, benefits of CCAF are illustrated using several bioinformatics examples such as tumour modelling, brain imaging, insulin molecules and simulations for medical training. Our Cloud Storage solution described here offers cost reduction, time-saving and user friendliness
InterCloud: Utility-Oriented Federation of Cloud Computing Environments for Scaling of Application Services
Cloud computing providers have setup several data centers at different
geographical locations over the Internet in order to optimally serve needs of
their customers around the world. However, existing systems do not support
mechanisms and policies for dynamically coordinating load distribution among
different Cloud-based data centers in order to determine optimal location for
hosting application services to achieve reasonable QoS levels. Further, the
Cloud computing providers are unable to predict geographic distribution of
users consuming their services, hence the load coordination must happen
automatically, and distribution of services must change in response to changes
in the load. To counter this problem, we advocate creation of federated Cloud
computing environment (InterCloud) that facilitates just-in-time,
opportunistic, and scalable provisioning of application services, consistently
achieving QoS targets under variable workload, resource and network conditions.
The overall goal is to create a computing environment that supports dynamic
expansion or contraction of capabilities (VMs, services, storage, and database)
for handling sudden variations in service demands.
This paper presents vision, challenges, and architectural elements of
InterCloud for utility-oriented federation of Cloud computing environments. The
proposed InterCloud environment supports scaling of applications across
multiple vendor clouds. We have validated our approach by conducting a set of
rigorous performance evaluation study using the CloudSim toolkit. The results
demonstrate that federated Cloud computing model has immense potential as it
offers significant performance gains as regards to response time and cost
saving under dynamic workload scenarios.Comment: 20 pages, 4 figures, 3 tables, conference pape
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