Awareness of form-sound correspondence in Chinese children with dyslexia: Preliminary results from event-related potentials and time frequency analyses

Developmental dyslexia has usually been characterized as having difficulties learning grapheme-phoneme correspondence and applying the mappings. This study investigates form-sound awareness in Chinese reading-impaired children in terms of regularity, consistency and lexicality effects using event-related potentials (ERP) and time-frequency analysis (TFA). Preliminary data from two Cantonese-speaking male children, one with reading impairment (PR) and one with normal reading performance (CA), performing a character recognition task were collected. ERP results indicated that CA showed a lexicality effect at N400 that was not evident in PR. TFA showed that CA exhibited greater event-related synchronization (ERS) and phase coherence at theta and gamma bands suggesting greater cognitive demand in processing pseudo and irregular characters. An opposite pattern was observed for PR, where greater effort was needed to retrieve information related to real and regular characters whilst failing to respond to pseudo and irregular characters. Greater ERS and phase coherence was also observed for real, pseudo and regular characters at 350-450ms at theta suggesting adequate access to phonological and semantic information for CA compared to PR. Whereas PR showed greater ERS and phase coherence at earlier and later time intervals. These initial findings suggest that PR may have weaker semantic representations and may be less sensitive to the internal structure of characters and its relationship with sounds. © 2011 IEEE.published_or_final_versio

Brain processes during the perception of sensory signals in men with high and low output α-frequencies

Background: Human functional capabilities largely depend upon genetic qualities of person’s nervous system. The registration of the spontaneous electroencephalogram (EEG) is among the physiological technigues allowing making a direct estimation of specific features of the nervous system, in particular, the human brain activity. Purpose: The study is devoted to the investigation of brain processes in men with high and low levels of individual α-frequency determined in a quiescent state during the perception of sensory signals. Methods: A test group consisting of 104 right-hand healthy men from the ages of 19 to 21 was divided into two groups according to the magnitude of their individual α- frequency (IAF) median – groups with high (n = 53, IA ≥ 10,04 Hz) and low (n = 51, IAF≤10,03 Hz) levels of IAF. The power and coherence of the electrical activity of the cerebral cortex as well as inter group differences were evaluated in a quiescent state and during the perception of sensory signals by Subjects. Results: A localized power increase of the EEG α1-waves are registered in frontal areas, β1, β2- oscillations - in the anterior cortex , γ- activity - around the scalp and its decrease is present in the posterior temporal, parietal and occipital cortex leads, especially in the α- and β- frequency spectrum during the perception of sensory signals in men with a high IAF. The generalized depression of the θ-, α- and β- activity of the cortex is fixed in individuals with a low IAF while the expression of γ- waves is more local. The generalized increase of data in EEG coherence fluctuations throughout the frequency spectrum of the EEG in the cortex is set in all Subjects. The dextrocerebral preponderance is observable in posterior structures of the Subjects’ right hemisphere. A localized decrease of the coherence concerning θ-, α1-, α3-, β- and γ- oscillations are traced in the frontal and anterior temporal areas of the left hemisphere. Conclusion: We are of the opinion that the establishment of such common factors in the studied groups is an important step towards the release of the clear prognostic criteria for the functionality of men in the sensory area according to the congenital features of brain function

Electrical activity of the cerebral cortex in men having high or low output alpha-frequencies while performing usual manual movements in response to sensory signals

A test group consisting of 104 healthy men from the ages of 19 to 21 was divided into two groups according to the magnitude of their individual α- frequency (ІАF) median―groups with high (n = 53, IA ≥ 10,04 Hz) and low (n = 51, IAF ≤ 10,03 Hz) levels of ІАF. Changes in power and coherence of the EEG oscillations during the usual manual movements as well as intergroup differences were evaluated. The higher level of the background tone of the cortex activation in men with a high IAF (individual alpha-frequency) was found as correlative with a significant selection of the relevant sensory information and a nonspecific input afferentation and its weakening under the performance of habitual manual movements. A functional state of the cortex is relatively lower in men with a low IAF and compensated by the tension of brain processes associated with a low level of the selective attention and the increase of the reticular influences and their significance during the finger movements. Men with a high IAF are characterized by the greater locality and asymmetry of processes of the cortical excitation under the dominant role of the left hemisphere. Activation changes are more diffuse in nature in subjects having a low frequency

Просторова синхронізація й десинхронізація біопотенціалів ЕЕГ при когнітивній діяльності спортсменів

Досліджували особливості просторового розподілу когерентних зв’язків в α-, θ- та β- діапазонах ЕЕГ. У дослідженнях узяли участь 100 здорових праворуких юнаків 17–21 років, поділених на три групи: група спортсменів ациклічних видів спорту (33 особи) – юнаки, котрі займаються спортом з ациклічною структурою рухів; група спортсменів циклічних видів спорту (32 особи) – юнаки, котрі займаються спортом із циклічною структурою; контрольна група (35 осіб) – юнаки, які не займаються спортом регулярно. Просторовий розподіл зв’язків між відділами кори головного мозку під час когнітивної діяльності залежить від ранньої спортивної спеціалізації різного типу. Відтворення інформації з пам’яті, порівняно із завданням пошукового характеру, у групах спортсменів, а особливо в групі спортсменів ациклічних видів спорту, супроводжується синхронізацією біопотенціалів ЕЕГ. У контрольній групі достовірних відмінностей не виявлено

Word Class and Context Affect Alpha-Band Oscillatory Dynamics in an Older Population

Differences in the oscillatory EEG dynamics of reading open class (OC) and closed class (CC) words have previously been found (Bastiaansen et al., 2005) and are thought to reflect differences in lexical-semantic content between these word classes. In particular, the theta-band (4–7 Hz) seems to play a prominent role in lexical-semantic retrieval. We tested whether this theta effect is robust in an older population of subjects. Additionally, we examined how the context of a word can modulate the oscillatory dynamics underlying retrieval for the two different classes of words. Older participants (mean age 55) read words presented in either syntactically correct sentences or in a scrambled order (“scrambled sentence”) while their EEG was recorded. We performed time–frequency analysis to examine how power varied based on the context or class of the word. We observed larger power decreases in the alpha (8–12 Hz) band between 200–700 ms for the OC compared to CC words, but this was true only for the scrambled sentence context. We did not observe differences in theta power between these conditions. Context exerted an effect on the alpha and low beta (13–18 Hz) bands between 0 and 700 ms. These results suggest that the previously observed word class effects on theta power changes in a younger participant sample do not seem to be a robust effect in this older population. Though this is an indirect comparison between studies, it may suggest the existence of aging effects on word retrieval dynamics for different populations. Additionally, the interaction between word class and context suggests that word retrieval mechanisms interact with sentence-level comprehension mechanisms in the alpha-band

Interhemispheric and Intrahemispheric Connectivity From the Left Pars Opercularis Within the Language Network Is Modulated by Transcranial Stimulation in Healthy Subjects

Neural activity related to language can be modulated within widespread networks following learning or in response to disruption-including the experimental application of noninvasive brain stimulation. However, the spatiotemporal characteristics of such modulation remain insufficiently explored. The present study combined transcranial magnetic stimulation (TMS) and electroencephalography (EEG) to explore the modulation of activity across the language network following continuous theta-burst stimulation (cTBS) of the left pars opercularis. In 10 healthy subjects (21 ± 2 years old, four females), neuronavigated cTBS was delivered over the left pars opercularis of the frontal operculum (part of the traditional Broca's area) at 80% of active motor threshold (AMT) stimulation intensity. Real cTBS and sham cTBS were performed in two different visits separated by at least 48 h. Before, immediately, and 10 min after cTBS, 30 single pulses of TMS were delivered to the left pars opercularis at 80% of the resting motor threshold (RMT), whereas EEG was simultaneously recorded. We examined the cTBS-induced modulation of phase locking values (PLVs) between the TMS-evoked potentials (TEPs) recorded over the pars opercularis and those recorded over its right-hemispheric homolog area, the left supramarginal area, and the left superior temporal area in different EEG frequency bands and different time windows following cTBS. cTBS to the left pars opercularis induced within the gamma band: (1) a significant increase in TEP phase synchronization between the left and right pars opercularis at an early time window (250-350 ms) following cTBS; and (2) significantly increased PLV with the left supramarginal area and the left superior temporal area at a later time window (600-700 ms). In the theta and delta band, cTBS to the left pars opercularis induced significantly increased phase synchronization of TEPs between the left pars opercularis and the posterior left hemispheric language areas at a late time window. In sham condition, there was a significant decrease in TEP phase synchronization of the high beta band between left pars opercularis and left superior temporal area at 200-300 ms. These results contribute to characterize the dynamics of the language network and may have implications in the development of noninvasive stimulation protocols to promote the language rehabilitation in aphasia patients

Dynamic activity patterns in the anterior temporal lobe represents object semantics.

The anterior temporal lobe (ATL) is considered a crucial area for the representation of transmodal concepts. Recent evidence suggests that specific regions within the ATL support the representation of individual object concepts, as shown by studies combining multivariate analysis methods and explicit measures of semantic knowledge. This research looks to further our understanding by probing conceptual representations at a spatially and temporally resolved neural scale. Representational similarity analysis was applied to human intracranial recordings from anatomically defined lateral to medial ATL sub-regions. Neural similarity patterns were tested against semantic similarity measures, where semantic similarity was defined by a hybrid corpus-based and feature-based approach. Analyses show that the perirhinal cortex, in the medial ATL, significantly related to semantic effects around 200 to 400 ms, and were greater than more lateral ATL regions. Further, semantic effects were present in low frequency (theta and alpha) oscillatory phase signals. These results provide converging support that more medial regions of the ATL support the representation of basic-level visual object concepts within the first 400 ms, and provide a bridge between prior fMRI and MEG work by offering detailed evidence for the presence of conceptual representations within the ATL

Posterior Beta and Anterior Gamma Oscillations Predict Cognitive Insight

Pioneering neuroimaging studies on insight have revealed neural correlates of the emotional “Aha!” component of the insight process, but neural substrates of the cognitive component, such as problem restructuring (a key to transformative reasoning), remain a mystery. Here, multivariate electroencephalogram signals were recorded from human participants while they solved verbal puzzles that could create a small-scale experience of cognitive insight. Individuals responded as soon as they reached a solution and provided a rating of subjective insight. For unsolved puzzles, hints were provided after 60 to 90 sec. Spatio-temporal signatures of brain oscillations were analyzed using Morlet wavelet transform followed by exploratory parallel-factor analysis. A consistent reduction in beta power (15–25 Hz) was found over the parieto-occipital and centro-temporal electrode regions on all four conditions—(a) correct (vs. incorrect) solutions, (b) solutions without (vs. with) external hint, (c) successful (vs. unsuccessful) utilization of the external hint, and d) self-reported high (vs. low) insight. Gamma band (30–70 Hz) power was increased in right fronto-central and frontal electrode regions for conditions (a) and (c). The effects occurred several (up to 8) seconds before the behavioral response. Our findings indicate that insight is represented by distinct spectral, spatial, and temporal patterns of neural activity related to presolution cognitive processes that are intrinsic to the problem itself but not exclusively to one's subjective assessment of insight

Can Brain Signals Reveal Inner Alignment with Human Languages?

Brain Signals, such as Electroencephalography (EEG), and human languages have been widely explored independently for many downstream tasks, however, the connection between them has not been well explored. In this study, we explore the relationship and dependency between EEG and language. To study at the representation level, we introduced \textbf{MTAM}, a \textbf{M}ultimodal \textbf{T}ransformer \textbf{A}lignment \textbf{M}odel, to observe coordinated representations between the two modalities. We used various relationship alignment-seeking techniques, such as Canonical Correlation Analysis and Wasserstein Distance, as loss functions to transfigure features. On downstream applications, sentiment analysis and relation detection, we achieved new state-of-the-art results on two datasets, ZuCo and K-EmoCon. Our method achieved an F1-score improvement of 1.7% on K-EmoCon and 9.3% on Zuco datasets for sentiment analysis, and 7.4% on ZuCo for relation detection. In addition, we provide interpretations of the performance improvement: (1) feature distribution shows the effectiveness of the alignment module for discovering and encoding the relationship between EEG and language; (2) alignment weights show the influence of different language semantics as well as EEG frequency features; (3) brain topographical maps provide an intuitive demonstration of the connectivity in the brain regions. Our code is available at \url{https://github.com/Jason-Qiu/EEG_Language_Alignment}.Comment: EMNLP 2023 Finding

The lexical nature of alpha-beta oscillations in context-driven word production

In context-driven word production, picture naming is faster following constrained than neutral sentential contexts (e.g., “The farmer milked the… [picture]” vs. “The child drew a… [picture]”, followed by the picture of a cow), suggesting conceptual-lexical pre-activation of the target response. Power decreases in the alpha-beta oscillatory band (8–25 Hz) are consistently found for constrained relative to neutral contexts prior to picture onset, when conceptual and lexical retrieval is ongoing. However, it remains a matter of debate whether the alpha-beta power decreases reflect (low-level) expectations of the visual input, conceptual and lexical retrieval, or motor preparation. The present study aimed at investigating the lexical-semantic nature of alpha-beta oscillations. Participants performed context-driven picture naming with constrained and neutral contexts. In addition, an auditory distractor word was presented before picture onset. Distractors were either semantically related (e.g., “goat”) or unrelated (e.g., “bean”) to the picture to be named. Picture naming was faster with constrained than neutral contexts. Distractor type did not affect naming latencies nor the behavioural context effect. In the oscillatory brain responses, the context-related alpha-beta power decreases were observed throughout the pre-picture interval when distractors were semantically unrelated to the picture, in line with previous findings. However, with semantically related distractors, the context effect was delayed until a period after distractor processing. Thus, alpha-beta power seems to be sensitive to the semantic relationship between the distractor word and the picture to be named. We interpret these results as suggesting that alpha-beta power decreases in context-driven word production reflect lexical-semantic retrieval mechanisms