Utopia point method based robust vector polynomial optimization scheme

In this paper, we focus on a class of robust vector polynomial optimization problems (RVPOP in short) without any convex assumptions. By combining/improving the utopia point method (a nonlinear scalarization) for vector optimization and "joint+marginal" relaxation method for polynomial optimization, we solve the RVPOP successfully. Both theoratical and computational aspects are considered

Operations Research Methods for Optimization in Radiation Oncology

Operations Research has a successful tradition of applying mathematical analysis to a wide range of applications, and problems in Medical Physics have been popular over the last couple of decades. The original application was in the optimal design of the uence map for a radiotherapy treatment, a problem that has continued to receive attention. However, Operations Research has been applied to other clinical problems like patient scheduling, vault design, and image alignment. The overriding theme of this article is to present how techniques in Operations Research apply to clinical problems, which we accomplish in three parts. First, we present the perspective from which an operations researcher addresses a clinical problem. Second, we succinctly introduce the underlying methods that are used to optimize a system, and third, we demonstrate how modern software facilitates problem design. Our discussion is supported by several publications to foster continued study. With numerous clinical, medical, and managerial decisions associated with a clinic, operations research has a promising future at improving how radiotherapy treatments are designed and delivered

Contributions to fuzzy polynomial techniques for stability analysis and control

The present thesis employs fuzzy-polynomial control techniques in order to improve the stability analysis and control of nonlinear systems. Initially, it reviews the more extended techniques in the field of Takagi-Sugeno fuzzy systems, such as the more relevant results about polynomial and fuzzy polynomial systems. The basic framework uses fuzzy polynomial models by Taylor series and sum-of-squares techniques (semidefinite programming) in order to obtain stability guarantees. The contributions of the thesis are: ¿ Improved domain of attraction estimation of nonlinear systems for both continuous-time and discrete-time cases. An iterative methodology based on invariant-set results is presented for obtaining polynomial boundaries of such domain of attraction. ¿ Extension of the above problem to the case with bounded persistent disturbances acting. Different characterizations of inescapable sets with polynomial boundaries are determined. ¿ State estimation: extension of the previous results in literature to the case of fuzzy observers with polynomial gains, guaranteeing stability of the estimation error and inescapability in a subset of the zone where the model is valid. ¿ Proposal of a polynomial Lyapunov function with discrete delay in order to improve some polynomial control designs from literature. Preliminary extension to the fuzzy polynomial case. Last chapters present a preliminary experimental work in order to check and validate the theoretical results on real platforms in the future.Pitarch Pérez, JL. (2013). Contributions to fuzzy polynomial techniques for stability analysis and control [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/34773TESI

Network design decisions in supply chain planning

Structuring global supply chain networks is a complex decision-making process. The typical inputs to such a process consist of a set of customer zones to serve, a set of products to be manufactured and distributed, demand projections for the different customer zones, and information about future conditions, costs (e.g. for production and transportation) and resources (e.g. capacities, available raw materials). Given the above inputs, companies have to decide where to locate new service facilities (e.g. plants, warehouses), how to allocate procurement and production activities to the variousmanufacturing facilities, and how to manage the transportation of products through the supply chain network in order to satisfy customer demands. We propose a mathematical modelling framework capturing many practical aspects of network design problems simultaneously. For problems of reasonable size we report on computational experience with standard mathematical programming software. The discussion is extended with other decisions required by many real-life applications in strategic supply chain planning. In particular, the multi-period nature of some decisions is addressed by a more comprehensivemodel, which is solved by a specially tailored heuristic approach. The numerical results suggest that the solution procedure can identify high quality solutions within reasonable computational time