Digital watermarking : applicability for developing trust in medical imaging workflows state of the art review

Medical images can be intentionally or unintentionally manipulated both within the secure medical system environment and outside, as images are viewed, extracted and transmitted. Many organisations have invested heavily in Picture Archiving and Communication Systems (PACS), which are intended to facilitate data security. However, it is common for images, and records, to be extracted from these for a wide range of accepted practices, such as external second opinion, transmission to another care provider, patient data request, etc. Therefore, confirming trust within medical imaging workflows has become essential. Digital watermarking has been recognised as a promising approach for ensuring the authenticity and integrity of medical images. Authenticity refers to the ability to identify the information origin and prove that the data relates to the right patient. Integrity means the capacity to ensure that the information has not been altered without authorisation. This paper presents a survey of medical images watermarking and offers an evident scene for concerned researchers by analysing the robustness and limitations of various existing approaches. This includes studying the security levels of medical images within PACS system, clarifying the requirements of medical images watermarking and defining the purposes of watermarking approaches when applied to medical images

Preserving privacy in edge computing

Edge computing or fog computing enables realtime services to smart application users by storing data and services at the edge of the networks. Edge devices in the edge computing handle data storage and service provisioning. Therefore, edge computing has become a  new norm for several delay-sensitive smart applications such as automated vehicles, ambient-assisted living, emergency response services, precision agriculture, and smart electricity grids. Despite having great potential, privacy threats are the main barriers to the success of edge computing. Attackers can leak private or sensitive information of data owners and modify service-related data for hampering service provisioning in edge computing-based smart applications. This research takes privacy issues of heterogeneous smart application data into account that are stored in edge data centers. From there, this study focuses on the development of privacy-preserving models for user-generated smart application data in edge computing and edge service-related data, such as Quality-of-Service (QoS) data, for ensuring unbiased service provisioning. We begin with developing privacy-preserving techniques for user data generated by smart applications using steganography that is one of the data hiding techniques. In steganography, user sensitive information is hidden within nonsensitive information of data before outsourcing smart application data, and stego data are produced for storing in the edge data center. A steganography approach must be reversible or lossless to be useful in privacy-preserving techniques. In this research, we focus on numerical (sensor data) and textual (DNA sequence and text) data steganography. Existing steganography approaches for numerical data are irreversible. Hence, we introduce a lossless or reversible numerical data steganography approach using Error Correcting Codes (ECC). Modern lossless steganography approaches for text data steganography are mainly application-specific and lacks imperceptibility, and DNA steganography requires reference DNA sequence for the reconstruction of the original DNA sequence. Therefore, we present the first blind and lossless DNA sequence steganography approach based on the nucleotide substitution method in this study. In addition, a text steganography method is proposed that using invisible character and compression based encoding for ensuring reversibility and higher imperceptibility.  Different experiments are conducted to demonstrate the justification of our proposed methods in these studies. The searching capability of the stored stego data is challenged in the edge data center without disclosing sensitive information. We present a privacy-preserving search framework for stego data on the edge data center that includes two methods. In the first method, we present a keyword-based privacy-preserving search method that allows a user to send a search query as a hash string. However, this method does not support the range query. Therefore, we develop a range search method on stego data using an order-preserving encryption (OPE) scheme. In both cases, the search service provider retrieves corresponding stego data without revealing any sensitive information. Several experiments are conducted for evaluating the performance of the framework. Finally, we present a privacy-preserving service computation framework using Fully Homomorphic Encryption (FHE) based cryptosystem for ensuring the service provider's privacy during service selection and composition. Our contributions are two folds. First, we introduce a privacy-preserving service selection model based on encrypted Quality-of-Service (QoS) values of edge services for ensuring privacy. QoS values are encrypted using FHE. A distributed computation model for service selection using MapReduce is designed for improving efficiency. Second, we develop a composition model for edge services based on the functional relationship among edge services for optimizing the service selection process. Various experiments are performed in both centralized and distributed computing environments to evaluate the performance of the proposed framework using a synthetic QoS dataset

Data hiding techniques in steganography using fibonacci sequence and knight tour algorithm

The foremost priority in the information and communication technology era, is achieving an efficient and accurate steganography system for hiding information. The developed system of hiding the secret message must capable of not giving any clue to the adversaries about the hidden data. In this regard, enhancing the security and capacity by maintaining the Peak Signal-to-Noise Ratio (PSNR) of the steganography system is the main issue to be addressed. This study proposed an improved for embedding secret message into an image. This newly developed method is demonstrated to increase the security and capacity to resolve the existing problems. A binary text image is used to represent the secret message instead of normal text. Three stages implementations are used to select the pixel before random embedding to select block of (64 × 64) pixels, follows by the Knight Tour algorithm to select sub-block of (8 × 8) pixels, and finally by the random pixels selection. For secret embedding, Fibonacci sequence is implemented to decomposition pixel from 8 bitplane to 12 bitplane. The proposed method is distributed over the entire image to maintain high level of security against any kind of attack. Gray images from the standard dataset (USC-SIPI) including Lena, Peppers, Baboon, and Cameraman are implemented for benchmarking. The results show good PSNR value with high capacity and these findings verified the worthiness of the proposed method. High complexities of pixels distribution and replacement of bits will ensure better security and robust imperceptibility compared to the existing systems in the literature

Lossless and low-cost integer-based lifting wavelet transform

Discrete wavelet transform (DWT) is a powerful tool for analyzing real-time signals, including aperiodic, irregular, noisy, and transient data, because of its capability to explore signals in both the frequency- and time-domain in different resolutions. For this reason, they are used extensively in a wide number of applications in image and signal processing. Despite the wide usage, the implementation of the wavelet transform is usually lossy or computationally complex, and it requires expensive hardware. However, in many applications, such as medical diagnosis, reversible data-hiding, and critical satellite data, lossless implementation of the wavelet transform is desirable. It is also important to have more hardware-friendly implementations due to its recent inclusion in signal processing modules in system-on-chips (SoCs). To address the need, this research work provides a generalized implementation of a wavelet transform using an integer-based lifting method to produce lossless and low-cost architecture while maintaining the performance close to the original wavelets. In order to achieve a general implementation method for all orthogonal and biorthogonal wavelets, the Daubechies wavelet family has been utilized at first since it is one of the most widely used wavelets and based on a systematic method of construction of compact support orthogonal wavelets. Though the first two phases of this work are for Daubechies wavelets, they can be generalized in order to apply to other wavelets as well. Subsequently, some techniques used in the primary works have been adopted and the critical issues for achieving general lossless implementation have solved to propose a general lossless method. The research work presented here can be divided into several phases. In the first phase, low-cost architectures of the Daubechies-4 (D4) and Daubechies-6 (D6) wavelets have been derived by applying the integer-polynomial mapping. A lifting architecture has been used which reduces the cost by a half compared to the conventional convolution-based approach. The application of integer-polynomial mapping (IPM) of the polynomial filter coefficient with a floating-point value further decreases the complexity and reduces the loss in signal reconstruction. Also, the “resource sharing” between lifting steps results in a further reduction in implementation costs and near-lossless data reconstruction. In the second phase, a completely lossless or error-free architecture has been proposed for the Daubechies-8 (D8) wavelet. Several lifting variants have been derived for the same wavelet, the integer mapping has been applied, and the best variant is determined in terms of performance, using entropy and transform coding gain. Then a theory has been derived regarding the impact of scaling steps on the transform coding gain (GT). The approach results in the lowest cost lossless architecture of the D8 in the literature, to the best of our knowledge. The proposed approach may be applied to other orthogonal wavelets, including biorthogonal ones to achieve higher performance. In the final phase, a general algorithm has been proposed to implement the original filter coefficients expressed by a polyphase matrix into a more efficient lifting structure. This is done by using modified factorization, so that the factorized polyphase matrix does not include the lossy scaling step like the conventional lifting method. This general technique has been applied on some widely used orthogonal and biorthogonal wavelets and its advantages have been discussed. Since the discrete wavelet transform is used in a vast number of applications, the proposed algorithms can be utilized in those cases to achieve lossless, low-cost, and hardware-friendly architectures

Neutrosophic Adaptive LSB and Deep Learning Hybrid Framework for ECG Signal Classification

This paper proposes a novel hybrid framework for ECG signal classification and privacy preservation. The framework includes two phases: the first phase uses LSTM+CNN with attention gate for ECG classification, while the second phase utilizes adaptive least signal bit with neutrosophic for hiding important data during transmission. The proposed framework converts data into three sets of degrees (true, false, and intermediate) using neutrosophic and passes them to an embedding layer. In the sender part, the framework hides important data in ECG signal as true and false degrees, using the intermediate set as a shared dynamic key between sender and receiver. The receiver can reconstruct the important data using the shared dynamic key or the intermediate set. The proposed framework is more robust against attacks compared to other methods

Computer Methods and Programs in Biomedicine XXX (2013) XXX‐XXX 1 Effective Management of Medical Information through ROI-Lossless Fragile Image Watermarking Technique

In this article, we have proposed a blind, fragile and Region of Interest (ROI) lossless medical image watermarking (MIW) technique, providing an all-in-one solution tool to various medical data distribution and management issues like security, content authentication, safe archiving, controlled access retrieval and captioning etc. The proposed scheme combines lossless data compression and encryption technique to embed electronic health record (EHR)/DICOM metadata, image hash, indexing keyword, doctor identification code and tamper localization information in the medical images. Extensive experiments (both subjective and objective) were carried out to evaluate performance of the proposed MIW technique. The findings offer suggestive evidence that the proposed MIW scheme is an effective all-in-one solution tool to various issues of medical information management domain. Moreover, given its relative simplicity, the proposed scheme can be applied to the medical images to serve in many medical applications concerned with privacy protection, safety, and management etc. Keywords

Design of a secure architecture for the exchange of biomedical information in m-Health scenarios

El paradigma de m-Salud (salud móvil) aboga por la integración masiva de las más avanzadas tecnologías de comunicación, red móvil y sensores en aplicaciones y sistemas de salud, para fomentar el despliegue de un nuevo modelo de atención clínica centrada en el usuario/paciente. Este modelo tiene por objetivos el empoderamiento de los usuarios en la gestión de su propia salud (p.ej. aumentando sus conocimientos, promocionando estilos de vida saludable y previniendo enfermedades), la prestación de una mejor tele-asistencia sanitaria en el hogar para ancianos y pacientes crónicos y una notable disminución del gasto de los Sistemas de Salud gracias a la reducción del número y la duración de las hospitalizaciones. No obstante, estas ventajas, atribuidas a las aplicaciones de m-Salud, suelen venir acompañadas del requisito de un alto grado de disponibilidad de la información biomédica de sus usuarios para garantizar una alta calidad de servicio, p.ej. fusionar varias señales de un usuario para obtener un diagnóstico más preciso. La consecuencia negativa de cumplir esta demanda es el aumento directo de las superficies potencialmente vulnerables a ataques, lo que sitúa a la seguridad (y a la privacidad) del modelo de m-Salud como factor crítico para su éxito. Como requisito no funcional de las aplicaciones de m-Salud, la seguridad ha recibido menos atención que otros requisitos técnicos que eran más urgentes en etapas de desarrollo previas, tales como la robustez, la eficiencia, la interoperabilidad o la usabilidad. Otro factor importante que ha contribuido a retrasar la implementación de políticas de seguridad sólidas es que garantizar un determinado nivel de seguridad implica unos costes que pueden ser muy relevantes en varias dimensiones, en especial en la económica (p.ej. sobrecostes por la inclusión de hardware extra para la autenticación de usuarios), en el rendimiento (p.ej. reducción de la eficiencia y de la interoperabilidad debido a la integración de elementos de seguridad) y en la usabilidad (p.ej. configuración más complicada de dispositivos y aplicaciones de salud debido a las nuevas opciones de seguridad). Por tanto, las soluciones de seguridad que persigan satisfacer a todos los actores del contexto de m-Salud (usuarios, pacientes, personal médico, personal técnico, legisladores, fabricantes de dispositivos y equipos, etc.) deben ser robustas y al mismo tiempo minimizar sus costes asociados. Esta Tesis detalla una propuesta de seguridad, compuesta por cuatro grandes bloques interconectados, para dotar de seguridad a las arquitecturas de m-Salud con unos costes reducidos. El primer bloque define un esquema global que proporciona unos niveles de seguridad e interoperabilidad acordes con las características de las distintas aplicaciones de m-Salud. Este esquema está compuesto por tres capas diferenciadas, diseñadas a la medidas de los dominios de m-Salud y de sus restricciones, incluyendo medidas de seguridad adecuadas para la defensa contra las amenazas asociadas a sus aplicaciones de m-Salud. El segundo bloque establece la extensión de seguridad de aquellos protocolos estándar que permiten la adquisición, el intercambio y/o la administración de información biomédica -- por tanto, usados por muchas aplicaciones de m-Salud -- pero no reúnen los niveles de seguridad detallados en el esquema previo. Estas extensiones se concretan para los estándares biomédicos ISO/IEEE 11073 PHD y SCP-ECG. El tercer bloque propone nuevas formas de fortalecer la seguridad de los tests biomédicos, que constituyen el elemento esencial de muchas aplicaciones de m-Salud de carácter clínico, mediante codificaciones novedosas. Finalmente el cuarto bloque, que se sitúa en paralelo a los anteriores, selecciona herramientas genéricas de seguridad (elementos de autenticación y criptográficos) cuya integración en los otros bloques resulta idónea, y desarrolla nuevas herramientas de seguridad, basadas en señal -- embedding y keytagging --, para reforzar la protección de los test biomédicos.The paradigm of m-Health (mobile health) advocates for the massive integration of advanced mobile communications, network and sensor technologies in healthcare applications and systems to foster the deployment of a new, user/patient-centered healthcare model enabling the empowerment of users in the management of their health (e.g. by increasing their health literacy, promoting healthy lifestyles and the prevention of diseases), a better home-based healthcare delivery for elderly and chronic patients and important savings for healthcare systems due to the reduction of hospitalizations in number and duration. It is a fact that many m-Health applications demand high availability of biomedical information from their users (for further accurate analysis, e.g. by fusion of various signals) to guarantee high quality of service, which on the other hand entails increasing the potential surfaces for attacks. Therefore, it is not surprising that security (and privacy) is commonly included among the most important barriers for the success of m-Health. As a non-functional requirement for m-Health applications, security has received less attention than other technical issues that were more pressing at earlier development stages, such as reliability, eficiency, interoperability or usability. Another fact that has contributed to delaying the enforcement of robust security policies is that guaranteeing a certain security level implies costs that can be very relevant and that span along diferent dimensions. These include budgeting (e.g. the demand of extra hardware for user authentication), performance (e.g. lower eficiency and interoperability due to the addition of security elements) and usability (e.g. cumbersome configuration of devices and applications due to security options). Therefore, security solutions that aim to satisfy all the stakeholders in the m-Health context (users/patients, medical staff, technical staff, systems and devices manufacturers, regulators, etc.) shall be robust and, at the same time, minimize their associated costs. This Thesis details a proposal, composed of four interrelated blocks, to integrate appropriate levels of security in m-Health architectures in a cost-efcient manner. The first block designes a global scheme that provides different security and interoperability levels accordingto how critical are the m-Health applications to be implemented. This consists ofthree layers tailored to the m-Health domains and their constraints, whose security countermeasures defend against the threats of their associated m-Health applications. Next, the second block addresses the security extension of those standard protocols that enable the acquisition, exchange and/or management of biomedical information | thus, used by many m-Health applications | but do not meet the security levels described in the former scheme. These extensions are materialized for the biomedical standards ISO/IEEE 11073 PHD and SCP-ECG. Then, the third block proposes new ways of enhancing the security of biomedical standards, which are the centerpiece of many clinical m-Health applications, by means of novel codings. Finally the fourth block, with is parallel to the others, selects generic security methods (for user authentication and cryptographic protection) whose integration in the other blocks results optimal, and also develops novel signal-based methods (embedding and keytagging) for strengthening the security of biomedical tests. The layer-based extensions of the standards ISO/IEEE 11073 PHD and SCP-ECG can be considered as robust, cost-eficient and respectful with their original features and contents. The former adds no attributes to its data information model, four new frames to the service model |and extends four with new sub-frames|, and only one new sub-state to the communication model. Furthermore, a lightweight architecture consisting of a personal health device mounting a 9 MHz processor and an aggregator mounting a 1 GHz processor is enough to transmit a 3-lead electrocardiogram in real-time implementing the top security layer. The extra requirements associated to this extension are an initial configuration of the health device and the aggregator, tokens for identification/authentication of users if these devices are to be shared and the implementation of certain IHE profiles in the aggregator to enable the integration of measurements in healthcare systems. As regards to the extension of SCP-ECG, it only adds a new section with selected security elements and syntax in order to protect the rest of file contents and provide proper role-based access control. The overhead introduced in the protected SCP-ECG is typically 2{13 % of the regular file size, and the extra delays to protect a newly generated SCP-ECG file and to access it for interpretation are respectively a 2{10 % and a 5 % of the regular delays. As regards to the signal-based security techniques developed, the embedding method is the basis for the proposal of a generic coding for tests composed of biomedical signals, periodic measurements and contextual information. This has been adjusted and evaluated with electrocardiogram and electroencephalogram-based tests, proving the objective clinical quality of the coded tests, the capacity of the coding-access system to operate in real-time (overall delays of 2 s for electrocardiograms and 3.3 s for electroencephalograms) and its high usability. Despite of the embedding of security and metadata to enable m-Health services, the compression ratios obtained by this coding range from ' 3 in real-time transmission to ' 5 in offline operation. Complementarily, keytagging permits associating information to images (and other signals) by means of keys in a secure and non-distorting fashion, which has been availed to implement security measures such as image authentication, integrity control and location of tampered areas, private captioning with role-based access control, traceability and copyright protection. The tests conducted indicate a remarkable robustness-capacity tradeoff that permits implementing all this measures simultaneously, and the compatibility of keytagging with JPEG2000 compression, maintaining this tradeoff while setting the overall keytagging delay in only ' 120 ms for any image size | evidencing the scalability of this technique. As a general conclusion, it has been demonstrated and illustrated with examples that there are various, complementary and structured manners to contribute in the implementation of suitable security levels for m-Health architectures with a moderate cost in budget, performance, interoperability and usability. The m-Health landscape is evolving permanently along all their dimensions, and this Thesis aims to do so with its security. Furthermore, the lessons learned herein may offer further guidance for the elaboration of more comprehensive and updated security schemes, for the extension of other biomedical standards featuring low emphasis on security or privacy, and for the improvement of the state of the art regarding signal-based protection methods and applications