Semi-quantitative proteomics of mammalian cells upon short-term exposure to nonionizing electromagnetic fields

The potential effects of non-ionizing electromagnetic fields (EMFs), such as those emitted by power-lines (in extremely low frequency range), mobile cellular systems and wireless networking devices (in radio frequency range) on human health have been intensively researched and debated. However, how exposure to these EMFs may lead to biological changes underlying possible health effects is still unclear. To reveal EMF-induced molecular changes, unbiased experiments (without a priori focusing on specific biological processes) with sensitive readouts are required. We present the first proteome-wide semi-quantitative mass spectrometry analysis of human fibroblasts, osteosarcomas and mouse embryonic stem cells exposed to three types of non-ionizing EMFs (ELF 50 Hz, UMTS 2.1 GHz and WiFi 5.8 GHz). We performed controlled in vitro EMF exposures of metabolically labeled mammalian cells followed by reliable statistical analyses of differential protein-and pathway-level regulations using an array of established bioinformatics methods. Our results indicate that less than 1% of the quantitated human or mouse proteome responds to the EMFs by small changes in protein abundance. Further network-based analysis of the differentially regulated proteins did not detect significantly perturbed cellular processes or pathways in human and mouse cells in response to ELF, UMTS or WiFi exposure. In conclusion, our extensive bioinformatics analyses of semi-quantitative mass spectrometry data do not support the notion that the short-time exposures to non-ionizing EMFs have a consistent biologically significant bearing on mammalian cells in culture

A novel approach to emergency management of wireless telecommunication system

The survivability concerns the service continuity when the components of a system are damaged. This concept is especially useful in the emergency management of the system, as often emergencies involve accidents or incident disasters which more or less damage the system. The overall objective of this thesis study is to develop a quantitative management approach to the emergency management of a wireless cellular telecommunication system in light of its service continuity in emergency situations – namely the survivability of the system. A particular wireless cellular telecommunication system, WCDMA, is taken as an example to ground this research.The thesis proposes an ontology-based paradigm for service management such that the management system contains three models: (1) the work domain model, (2) the dynamic model, and (3) the reconfiguration model. A powerful work domain modeling tool called Function-Behavior-Structure (FBS) is employed for developing the work domain model of the WCDMA system. Petri-Net theory, as well as its formalization, is applied to develop the dynamic model of the WCDMA system. A concept in engineering design called the general and specific function concept is applied to develop a new approach to system reconfiguration for the high survivability of the system. These models are implemented along with a user-interface which can be used by emergency management personnel. A demonstration of the effectiveness of this study approach is included.There are a couple of contributions with this thesis study. First, the proposed approach can be added to contemporary telecommunication management systems. Second, the Petri Net model of the WCDMA system is more comprehensive than any dynamic model of the telecommunication systems in literature. Furthermore, this model can be extended to any other telecommunication system. Third, the proposed system reconfiguration approach, based on the general and specific function concept, offers a unique way for the survivability of any service provider system.In conclusion, the ontology-based paradigm for a service system management provides a total solution to service continuity as well as its emergency management. This paradigm makes the complex mathematical modeling of the system transparent to the manager or managerial personnel and provides a feasible scenario of the human-in-the-loop management

04411 Abtracts Collection -- Service Management and Self-Organization in IP-based Networks

From 03.10.04 to 06.10.04, the Dagstuhl Seminar 04411 ``Service Management and Self-Organization in IP-based Networks\u27\u27 was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the seminar topics and goals in general. Links to extended abstracts or full papers are provided, if available

SecMon: End-to-End Quality and Security Monitoring System

The Voice over Internet Protocol (VoIP) is becoming a more available and popular way of communicating for Internet users. This also applies to Peer-to-Peer (P2P) systems and merging these two have already proven to be successful (e.g. Skype). Even the existing standards of VoIP provide an assurance of security and Quality of Service (QoS), however, these features are usually optional and supported by limited number of implementations. As a result, the lack of mandatory and widely applicable QoS and security guaranties makes the contemporary VoIP systems vulnerable to attacks and network disturbances. In this paper we are facing these issues and propose the SecMon system, which simultaneously provides a lightweight security mechanism and improves quality parameters of the call. SecMon is intended specially for VoIP service over P2P networks and its main advantage is that it provides authentication, data integrity services, adaptive QoS and (D)DoS attack detection. Moreover, the SecMon approach represents a low-bandwidth consumption solution that is transparent to the users and possesses a self-organizing capability. The above-mentioned features are accomplished mainly by utilizing two information hiding techniques: digital audio watermarking and network steganography. These techniques are used to create covert channels that serve as transport channels for lightweight QoS measurement's results. Furthermore, these metrics are aggregated in a reputation system that enables best route path selection in the P2P network. The reputation system helps also to mitigate (D)DoS attacks, maximize performance and increase transmission efficiency in the network.Comment: Paper was presented at 7th international conference IBIZA 2008: On Computer Science - Research And Applications, Poland, Kazimierz Dolny 31.01-2.02 2008; 14 pages, 5 figure

INTELLIGENTE TRANSPORT SYSTEMEN ITS EN VERKEERSVEILIGHEID

This report discusses Intelligent Transport Systems (ITS). This generic term is used for a broad range of information-, control- and electronic technology that can be integrated in the road infrastructure and the vehicles themselves, saving lives, time and money bymonitoring and managing traffic flows, reducing conges-tion, avoiding accidents, etc. Because this report was written in the scope of the Policy Research Centre Mobility & Public Works, track Traffic Safety, it focuses on ITS systems from the traffic safety point of view. Within the whole range of ITS systems, two categories can be distinguished: autonomous and cooperative systems. Autonomous systems are all forms of ITS which operate by itself, and do not depend on the cooperation with other vehicles or supporting infrastructure. Example applications are blind spot detection using radar, electronic stability control, dynamic traffic management using variable road signs, emergency call, etc. Cooperative systems are ITS systems based on communication and cooperation, both between vehicles as between vehicles and infrastructure. Example applications are alerting vehicles approaching a traffic jam, exchanging data regarding hazardous road conditions, extended electronic brake light, etc. In some cases, autonomous systems can evolve to autonomous cooperative systems. ISA (Intelligent Speed Adaptation) is an example of this: the dynamic aspect as well as communication with infrastructure (eg Traffic lights, Variable Message Sign (VMS)...) can provide additional road safety. This is the clear link between the two parts of this report. The many ITS applications are an indicator of the high expectations from the government, the academic world and the industry regarding the possibilities made possible by both categories of ITS systems. Therefore, the comprehensive discussion of both of them is the core of this report. The first part of the report covering the autonomous systems treats two aspects: 1. Overview of European projects related to mobility and in particular to road safety 2. Overview for guidelines for the evaluation of ITS projects. Out of the wide range of diverse (autonomous) ITS applications a selection is made; this selection is focused on E Safety Forum and PreVENT. Especially the PreVent research project is interesting because ITS-applications have led to a number of concrete demonstration vehicles that showed - in protected and unprotected surroundings- that these ITS-applications are already technically useful or could be developed into useful products. The component “guidelines for the evaluation of ITS projects” outlines that the government has to have specific evaluation tools if the government has the ambition of using ITS-applications for road safety. Two projects -guidelines for the evaluation of ITS projects- are examined; a third evaluation method is only mentioned because this description shows that a specific targeting of the government can be desirable : 1. TRACE describes the guidelines for the evaluation of ITS projects which are useful for the evaluation of specific ITS-applications. 2. FITS contains Finnish guidelines for the evaluation of ITS project; FIS is an adaptation of methods used for evaluation of transport projects. 3. The third evaluation method for the evaluation of ITS projects is developed in an ongoing European research project, eImpact. eImpact is important because, a specific consultation of stake holders shows that the social importance of some techniques is underestimated. These preliminary results show that an appropriate guiding role for the government could be important. In the second part of this document the cooperative systems are discussed in depth. These systems enable a large number of applications with an important social relevance, both on the level of the environment, mobility and traffic safety. Cooperative systems make it possible to warn drivers in time to avoid collisions (e.g. when approaching the tail of a traffic jam, or when a ghost driver is detected). Hazardous road conditions can be automatically communicated to other drivers (e.g. after the detection of black ice or an oil trail by the ESP). Navigation systems can receive detailed real-time up-dates about the current traffic situation and can take this into account when calculating their routes. When a traffic distortion occurs, traffic centers can immediately take action and can actively influence the way that the traffic will be diverted. Drivers can be notified well in advance about approaching emergency vehicles, and can be directed to yield way in a uniform manner. This is just a small selection from the large number of applications that are made possible because of cooperative ITS systems, but it is very obvious that these systems can make a significant positive contribution to traffic safety. In literature it is estimated that the decrease of accidents with injuries of fatalities will be between 20% and 50% . It is not suprising that ITS systems receive a lot of attention for the moment. On an international level, a number of standards are being established regarding this topic. The International Telecommunications Uniont (ITU), Institute for Electrical and Electronics Engineers (IEEE), International Organization for Standardization (ISO), Association of Radio Industries and Business (ARIB) and European committee for standardization (CEN) are currently defining standards that describe different aspects of ITS systems. One of the names that is mostly mentioned in literature is the ISO TC204/WG16 Communications Architecture for Land Mobile environment (CALM) standard. It describes a framework that enables transparent (both for the application and the user) continuous communication through different communication media. Besides the innumerable standardization activities, there is a great number of active research projects. On European level, the most important are the i2010 Intelligent Car Initiative, the eSafety Forum, and the COMeSafety, the CVIS, the SAFESPOT, the COOPERS and the SEVECOM project. The i2010 Intelligent Car Initiative is an European initiative with the goal to halve the number of traffic casualties by 2010. The eSafety Forum is an initiative of the European Commission, industry and other stakeholders and targets the acceleration of development and deployment of safety-related ITS systems. The COMeSafety project supports the eSafety Forum on the field of vehicle-to-vehicle and vehicle-to-infrastructure communication. In the CVIS project, attention is given to both technical and non-technical issues, with the main goal to develop the first free and open reference implementation of the CALM architecture. The SAFEST project investigates which data is important for safety applications, and with which algorithmsthis data can be extracted from vehicles and infrastructure. The COOPERS project mainly targets communication between vehicles and dedicated roadside infrastructure. Finally, the SEVECOM project researches security and privacy issues. Besides the European projects, research is also conducted in the United States of America (CICAS and VII projects) and in Japan (AHSRA, VICS, Smartway, internetITS). Besides standardization bodies and governmental organizations, also the industry has a considerable interest in ITS systems. In the scope of their ITS activities, a number of companies are united in national and international organizations. On an international level, the best known names are the Car 2 Car Communication Consortium, and Ertico. The C2C CC unites the large European car manufacturers, and focuses on the development of an open standard for vehicle-to-vehicle and vehicle-to-infrastructure communications based on the already well established IEEE 802.11 WLAN standard. Ertico is an European multi-sector, public/private partnership with the intended purpose of the development and introduction of ITS systems. On a national level, FlandersDrive and The Telematics Cluster / ITS Belgium are the best known organizations. Despite the worldwide activities regarding (cooperative) ITS systems, there still is no consensus about the wireless technology to be used in such systems. This can be put down to the fact that a large number of suitable technologies exist or are under development. Each technology has its specific advantages and disadvantages, but no single technology is the ideal solution for every ITS application. However, the different candidates can be classified in three distinct categories. The first group contains solutions for Dedicated Short Range Communication (DSRC), such as the WAVE technology. The second group is made up of several cellular communication networks providing coverage over wide areas. Examples are GPRS (data communication using the GSM network), UMTS (faster then GPRS), WiMAX (even faster then UMTS) and MBWA (similar to WiMAX). The third group consists of digital data broadcast technologies such as RDS (via the current FM radio transmissions, slow), DAB and DMB (via current digital radio transmissions, quicker) and DVB-H (via future digital television transmissions for mobiledevices, quickest). The previous makes it clear that ITS systems are a hot topic right now, and they receive a lot of attention from the academic world, the standardization bodies and the industry. Therefore, it seems like that it is just a matter of time before ITS systems will find their way into the daily live. Due to the large number of suitable technologies for the implementation of cooperative ITS systems, it is very hard to define which role the government has to play in these developments, and which are the next steps to take. These issues were addressed in reports produced by the i2010 Intelligent Car Initiative and the CVIS project. Their state of the art overview revealed that until now, no country has successfully deployed a fully operational ITS system yet. Seven EU countries are the furthest and are already in the deployment phase: Sweden, Germany, the Netherlands, the United Kingdom, Finland, Spain and France. These countries are trailed by eight countries which are in the promotion phase: Denmark, Greece, Italy, Austria, Belgium,Norway, the Czech Republic and Poland. Finally, the last ten countries find themselves in the start-up phase: Estonia, Lithuania, Latvia, Slovenia, Slovakia, Hungary, Portugal, Switzerland, Ireland and Luxembourg. These European reports produced by the i2010 Intelligent Car Initiative and the CVIS project have defined a few policy recommendations which are very relevant for the Belgian and Flemish government. The most important recommendations for the Flemish government are: • Support awareness: research revealed that civilians consider ITS applications useful, but they are not really willing to pay for this technology. Therefore, it is important to convince the general public of the usefulness and the importance of ITS systems. • Fill the gaps: Belgium is situated in the promotion phase. This means that it should focus at identifying the missing stakeholders, and coordinating national and regional ITS activities. Here it is important that the research activities are coordinated in a national and international context to allow transfer of knowledge from one study to the next, as well as the results to be comparable. • Develop a vision: in the scope of ITS systems policies have to be defined regarding a large number of issues. For instance there is the question if ITS users should be educated, meaning that the use of ITS systems should be the subject of the drivers license exam. How will the regulations be for the technical inspection of vehicles equipped with ITS technology? Will ITS systems be deployed on a voluntary base, or will they e.g. be obliged in every new car? Will the services be offered by private companies, by the public authorities, or by a combination of them? Which technology will be used to implement ITS systems? These are just a few of the many questions where the government will have to develop a point of view for. • Policy coordination: ITS systems are a policy subject on an international, national and regional level. It is very important that these policy organizations can collaborate in a coordinated manner. • Iterative approach to policy development: developing policies for this complex matter is not a simple task. This asks for an iterative approach, where policy decisions are continuously refined and adjusted

Infraestrutura de beira de estrada para apoio a sistemas cooperativos e inteligentes de transportes

The growing need of mobility along with the evolution of the automotive industry and the massification of the personal vehicle amplifies some of the road-related problems such as safety and traffic congestion. To mitigate such issues, the evolution towards cooperative communicating technologies and autonomous systems is considered a solution to overcome the human physical limitations and the limited perception horizon of on-board sensors. Short-range vehicular communications such as Vehicle-to-Vehicle or Vehicle-to-Infrastructure (ETSI ITS-G5) in conjunction with long-range cellular communications (LTE,5G) and standardized messages, emerge as viable solutions to amplify the benefits that standalone technologies can bring to the road environment, by covering a wide array of applications and use cases. In compliance with the standardization work from European Telecommunications Standards Institute (ETSI), this dissertation describes the implementation of the collective perception service in a real road infrastructure to assist the maneuvers of autonomous vehicles and provide information to a central road operator. This work is focused on building standardized collective perception messages (CPM) by retrieving information from traffic classification radars (installed in the PASMO project) for local dissemination using ETSI ITS-G5 radio technology and creating a redundant communication channel between the road infrastructure and a central traffic control centre, located at the Instituto de Telecomunicações - Aveiro, taking advantage of cellular, point-to-point radio links and optical fiber communications. The output of the messages are shown to the user by a mobile application. The service is further improved by building an algorithm for optimizing the message dissemination to improve channel efficiency in more demanding scenarios. The results of the experimental tests showed that the time delay between the production event of the collective perception message and the reception by other ITS stations is within the boundaries defined by ETSI standards. Moreover, the algorithm for message dissemination also shows to increase radio channel efficiency by limiting the number of objects disseminated by CPM messages. The collective perception service developed and the road infrastructure are therefore, a valuable asset to provide useful information for improving road safety and fostering the deployment of intelligent cooperative transportation systems.A crescente necessidade de mobilidade em paralelo com a evolução da indústria automóvel e com a massificação do uso de meios de transportes pessoais, têm vindo a amplificar alguns problemas dos transportes rodoviários, tais como a segurança e o congestionamento do tráfego. Para mitigar estas questões, a evolução das tecnologias de comunicação cooperativas e dos sistemas autónomos é vista como uma potencial solução para ultrapassar limitações dos condutores e do horizonte de perceção dos sensores veículares. Comunicações de curto alcance, tais como Veículo-a-Veículo ou Veículo-a-Infrastrutura (ETSI ITS-G5), em conjunto com comunicações móveis de longo alcance (LTE,5G) e mensagens padrão, emergem como soluções viáveis para amplificar todos os beneficios que tecnologias independentes podem trazer para o ambiente rodoviário, cobrindo um grande leque de aplicações e casos de uso da estrada. Em conformidade com o trabalho de padronização da European Telecommunications Standards Institute, esta dissertação descreve a implementação do serviço de perceção coletiva, numa infrastrutura rodoviária real, para suporte a manobras de veículos autónomos e para fornecer informações aos operadores de estradas. Este trabalho foca-se na construção de mensagens de perceção coletiva a partir de informação gerada por radares de classificação de tráfego (instalados no âmbito do projeto PASMO) para disseminação local usando a tecnologia rádio ETSI ITS-G5 e criando um canal de comunicação redundante entre a infraestrutura rodóviaria e um centro de controlo de tráfego localizado no Instituto de Telecomunicações - Aveiro, usando para isso: redes móveis, ligações rádio ponto a ponto e fibra ótica. O conteúdo destas messagens é mostrado ao utilizador através de uma aplicação móvel. O serviço é ainda melhorado, tendo-se para tal desenvolvido um algoritmo de otimização de disseminação das mensagens, tendo em vista melhorar a eficiência do canal de transmissão em cenários mais exigentes. Os resultados dos testes experimentais efetuados revelaram que o tempo de atraso entre o evento de produção de uma mensagem de perceção coletiva e a receção por outra estação ITS, usando comunicações ITS-G5, se encontra dentro dos limites definidos pelos padrões da ETSI. Além disso, o algoritmo para disseminação de mensagens também mostrou aumentar a eficiência do canal de rádio, limitando o número de objetos disseminados pelas mesmas. Assim, o serviço de perceção coletiva desenvolvido poderá ser uma ferramenta valiosa, contribuindo para o aumento da segurança rodóviaria e para a disseminação da utilização dos sistemas cooperativos de transporte inteligente.Mestrado em Engenharia Eletrónica e Telecomunicaçõe

Supervisor virtual machine for VoLTE service on a cloud environment

With the continuing growth of Voice of Long Term Evolution (VoLTE) networks, coupled with the need of Mobile Operators to reduce maintenance costs, Cloud Service deployment is becoming a common application. This study was designed to create a method capable of improving the Operations and Monitoring activities of a VoLTE service that is deployed on a Cloud platform. In this study, we present contents referring to the constituent elements of a VoLTE network, and we review in detail the features of the Telephony Application Server. For this study, TAS used was the Open TAS. Also included in this study is a generic explanation of Cloud Openstack’s behavior. The presented method implies the creation of a virtual machine Supervisor and its deployment in Cloud. This virtual machine is capable of establishing SSH connections with open TAS to extract the Clear Codes report, which identifies the state with which calls were terminated for analysis. The virtual machine contains defined limits, which check if they have been exceeded. If this a limit is excited, the virtual machine notifies the system operator of an incident. This study presents the possibilities of implementation in a Cloud environment, to improve and automate Operations and Maintenance functions in the Telecommunications network.Com o crescimento contínuo das redes de Voice over Long Term Evolution (VoLTE), juntamente com a necessidade de redução de custo de manutenção pelos Operadores Móveis, a implementação do Serviço em Cloud começa a ser uma aplicação comum. Este estudo foi elaborado com o intuito de criar um método capaz de melhorar as atividades de Operações e Monitorização de um serviço de VoLTE, que esteja implementado numa plataforma Cloud. Neste estudo, encontram-se presentes conteúdos referentes aos elementos constituintes de uma rede de VoLTE, e é revisto em detalhe as funcionalidades do Telephony Application Server. Para este estudo, o TAS utilizado foi o open TAS. Neste estudo, igualmente é incluído uma explicação genérica do comportamento da Cloud Openstack. O método apresentado implica criação de uma máquina virtual Supervisor e da sua implementação na Cloud. Esta máquina virtual é capaz de estabelecer ligações SSH com o open TAS, de modo a extrair o relatório de Clear Codes, que identifica o estado com que as chamadas foram finalizadas, para proceder a análises. A máquina virtual contém limites definidos, os quais verifica se foram excedidos. Caso este evento seja verificado, notificam o operador do sistema para um incidente. Esta é uma proposta que apresenta as possibilidades de implementação num ambiente de Cloud, em melhorar e automatizar as funções de Operações e Manutenção na rede de Telecomunicações