Post-Reconstruction Deconvolution of PET Images by Total Generalized Variation Regularization

Improving the quality of positron emission tomography (PET) images, affected by low resolution and high level of noise, is a challenging task in nuclear medicine and radiotherapy. This work proposes a restoration method, achieved after tomographic reconstruction of the images and targeting clinical situations where raw data are often not accessible. Based on inverse problem methods, our contribution introduces the recently developed total generalized variation (TGV) norm to regularize PET image deconvolution. Moreover, we stabilize this procedure with additional image constraints such as positivity and photometry invariance. A criterion for updating and adjusting automatically the regularization parameter in case of Poisson noise is also presented. Experiments are conducted on both synthetic data and real patient images.Comment: First published in the Proceedings of the 23rd European Signal Processing Conference (EUSIPCO-2015) in 2015, published by EURASI

A new steplength selection for scaled gradient methods with application to image deblurring

Gradient methods are frequently used in large scale image deblurring problems since they avoid the onerous computation of the Hessian matrix of the objective function. Second order information is typically sought by a clever choice of the steplength parameter defining the descent direction, as in the case of the well-known Barzilai and Borwein rules. In a recent paper, a strategy for the steplength selection approximating the inverse of some eigenvalues of the Hessian matrix has been proposed for gradient methods applied to unconstrained minimization problems. In the quadratic case, this approach is based on a Lanczos process applied every m iterations to the matrix of the most recent m back gradients but the idea can be extended to a general objective function. In this paper we extend this rule to the case of scaled gradient projection methods applied to non-negatively constrained minimization problems, and we test the effectiveness of the proposed strategy in image deblurring problems in both the presence and the absence of an explicit edge-preserving regularization term

Inexact Bregman iteration with an application to Poisson data reconstruction

This work deals with the solution of image restoration problems by an iterative regularization method based on the Bregman iteration. Any iteration of this scheme requires to exactly compute the minimizer of a function. However, in some image reconstruction applications, it is either impossible or extremely expensive to obtain exact solutions of these subproblems. In this paper, we propose an inexact version of the iterative procedure, where the inexactness in the inner subproblem solution is controlled by a criterion that preserves the convergence of the Bregman iteration and its features in image restoration problems. In particular, the method allows to obtain accurate reconstructions also when only an overestimation of the regularization parameter is known. The introduction of the inexactness in the iterative scheme allows to address image reconstruction problems from data corrupted by Poisson noise, exploiting the recent advances about specialized algorithms for the numerical minimization of the generalized Kullback–Leibler divergence combined with a regularization term. The results of several numerical experiments enable to evaluat

Inverse Problems with Poisson noise: Primal and Primal-Dual Splitting

In this paper, we propose two algorithms for solving linear inverse problems when the observations are corrupted by Poisson noise. A proper data fidelity term (log-likelihood) is introduced to reflect the Poisson statistics of the noise. On the other hand, as a prior, the images to restore are assumed to be positive and sparsely represented in a dictionary of waveforms. Piecing together the data fidelity and the prior terms, the solution to the inverse problem is cast as the minimization of a non-smooth convex functional. We establish the well-posedness of the optimization problem, characterize the corresponding minimizers, and solve it by means of primal and primal-dual proximal splitting algorithms originating from the field of non-smooth convex optimization theory. Experimental results on deconvolution and comparison to prior methods are also reported

Linear inverse problems with noise: primal and primal-dual splitting

In this paper, we propose two algorithms for solving linear inverse problems when the observations are corrupted by noise. A proper data fidelity term (log-likelihood) is introduced to reflect the statistics of the noise (e.g. Gaussian, Poisson). On the other hand, as a prior, the images to restore are assumed to be positive and sparsely represented in a dictionary of waveforms. Piecing together the data fidelity and the prior terms, the solution to the inverse problem is cast as the minimization of a non-smooth convex functional. We establish the well-posedness of the optimization problem, characterize the corresponding minimizers, and solve it by means of primal and primal-dual proximal splitting algorithms originating from the field of non-smooth convex optimization theory. Experimental results on deconvolution, inpainting and denoising with some comparison to prior methods are also reported

Deconvolution under Poisson noise using exact data fidelity and synthesis or analysis sparsity priors

In this paper, we propose a Bayesian MAP estimator for solving the deconvolution problems when the observations are corrupted by Poisson noise. Towards this goal, a proper data fidelity term (log-likelihood) is introduced to reflect the Poisson statistics of the noise. On the other hand, as a prior, the images to restore are assumed to be positive and sparsely represented in a dictionary of waveforms such as wavelets or curvelets. Both analysis and synthesis-type sparsity priors are considered. Piecing together the data fidelity and the prior terms, the deconvolution problem boils down to the minimization of non-smooth convex functionals (for each prior). We establish the well-posedness of each optimization problem, characterize the corresponding minimizers, and solve them by means of proximal splitting algorithms originating from the realm of non-smooth convex optimization theory. Experimental results are conducted to demonstrate the potential applicability of the proposed algorithms to astronomical imaging datasets