126,038 research outputs found
Population structure of graptolite assemblages
Graptolite rhabdosomes display a diverse suite of morphologies. The range of morphotypes present within most moderate to high diversity assemblages from the Ordovician and Silurian is similar, despite the different taxonomic composition of the faunas at different times. Survivorship analyses of graptolite faunas from the Ordovician and Silurian demonstrate strong similarities in the mortality rates of unrelated graptolites of similar functional morphology. It also shows a strong correlation of decreasing mortality rates amongst more mature colonies with increasing rhabdosome complexity. This similarity in both functional morphology and life history of graptolites suggests that they lived within a very stable planktic community structure
The population structure of Pseudomonas aeruginosa is characterized by genetic isolation of exoU+ and exoS+ lineages
The diversification of microbial populations may be driven by many factors including adaptation to distinct ecological niches and barriers to recombination. We examined the population structure of the bacterial pathogen Pseudomonas aeruginosa by analyzing whole-genome sequences of 739 isolates from diverse sources. We confirmed that the population structure of P. aeruginosa consists of two major groups (referred to as Groups A and B) and at least two minor groups (Groups C1 and C2). Evidence for frequent intra-group but limited inter-group recombination in the core genome was observed, consistent with sexual isolation of the groups. Likewise, accessory genome analysis demonstrated more gene flow within Groups A and B than between these groups, and a few accessory genomic elements were nearly specific to one or the other group. In particular, the exoS gene was highly over-represented in Group A compared to Group B isolates (99.4% vs. 1.1%) and the exoU gene was highly over-represented in Group B compared to Group A isolates (95.2% vs. 1.8%). The exoS and exoU genes encode effector proteins secreted by the P. aeruginosa type III secretion system. Together these results suggest that the major P. aeruginosa groups defined in part by the exoS and exoU genes are divergent from each other, and that these groups are genetically isolated and may be ecologically distinct. Although both groups were globally distributed and caused human infections, certain groups predominated in some clinical contexts
Population structure of Pacific yellowfin tuna
ENGLISH: The population structure and production of Pacific yellowfin tuna, Thunnus albacares, were examined by studying most of the basic data available on stock assessment, as well as other data, for the period 1965 to 1972. The data were obtained mainly from the Japanese longline fishery in the Pacific Ocean east of about 1200E and from the purse-seine fishery in the eastern Pacific east of about 140oW. Data from genetic studies of subpopulations were not used due to their preliminary nature.
It was concluded that the concept of "semi-independent" subpopulations proposed by Kamimura and Honma (1963) and Royce (1964) defines the population structure of Pacific yellowfin. At least three stocks (i.e. western, central and eastern), relatively independent of each other, are thought to exist, but the actual number and location of subpopulations is still unclear. Possible north-south separations, indicated to some extent by genetic studies and tagging, could be neither substantiated nor rejected on the basis of this study.
Finally, unless some major change in the fishing technology occurs, it is doubtful if any significant sustainable increase in yellowfin production from the Pacific is possible. The greatest potential for increase, if any, appears to be based on changing the size structure of yellowfin in the catch from the central Pacific. SPANISH: Se examino la estructura de la población y la producción del atún aleta amarilla del Pacifico Thunnus albacares para estudiar la mayoría de los datos básicos que se tenían sobre el avalúo de la población, como también otra información correspondiente al periodo de 1965·1972. Los datos fueron obtenidos principalmente de las pescas palangreros japonesas del Océano Pacifico al este de los 1200 E y de las pescas con redes de cerco del Pacifico oriental, al este de los 140oW. No se emplearon los datos de estudios genéticos de las subpoblaciones porque eran mas bien preliminares. Se concluyo que el concepto propuesto por Kamimura y Honma (1963) y Royce (1964) de subpoblaciones "semiindependientes" define la estructura de la población del aleta amarilla en el Pacifico. Se cree que existen por 10 menos tres existencias (e.d. la occidental, central y oriental), relativamente independientes la una de la otra, pero no se conoce con certeza cuantas subpoblaciones hay y donde se encuentran. La posible separación norte-sur, indicada, hasta cierto punto, por los análisis genéticos y del marcado, no puede ni confirmarse ni rechazarse basados en este estudio. Finalmente, a no ser que ocurra algún gran cambio en la tecnología pesquera es dudoso que sea posible obtener un aumento constante e importante en la producción del aleta amarilla del Pacifico. El potencial mayor de aumento, si es que existe alguno, parece que se basa en el cambio de la estructura de talla en la captura del aleta amarilla del Pacifico central.
(PDF contains 169 pages.
Evolutionary dynamics on any population structure
Evolution occurs in populations of reproducing individuals. The structure of
a biological population affects which traits evolve. Understanding evolutionary
game dynamics in structured populations is difficult. Precise results have been
absent for a long time, but have recently emerged for special structures where
all individuals have the same number of neighbors. But the problem of
determining which trait is favored by selection in the natural case where the
number of neighbors can vary, has remained open. For arbitrary selection
intensity, the problem is in a computational complexity class which suggests
there is no efficient algorithm. Whether there exists a simple solution for
weak selection was unanswered. Here we provide, surprisingly, a general formula
for weak selection that applies to any graph or social network. Our method uses
coalescent theory and relies on calculating the meeting times of random walks.
We can now evaluate large numbers of diverse and heterogeneous population
structures for their propensity to favor cooperation. We can also study how
small changes in population structure---graph surgery---affect evolutionary
outcomes. We find that cooperation flourishes most in societies that are based
on strong pairwise ties.Comment: 68 pages, 10 figure
Gene-history correlation and population structure
Correlation of gene histories in the human genome determines the patterns of
genetic variation (haplotype structure) and is crucial to understanding genetic
factors in common diseases. We derive closed analytical expressions for the
correlation of gene histories in established demographic models for genetic
evolution and show how to extend the analysis to more realistic (but more
complicated) models of demographic structure. We identify two contributions to
the correlation of gene histories in divergent populations: linkage
disequilibrium, and differences in the demographic history of individuals in
the sample. These two factors contribute to correlations at different length
scales: the former at small, and the latter at large scales. We show that
recent mixing events in divergent populations limit the range of correlations
and compare our findings to empirical results on the correlation of gene
histories in the human genome.Comment: Revised and extended version: 26 pages, 5 figures, 1 tabl
Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models.
Although genome-wide association studies (GWASs) have discovered numerous novel genetic variants associated with many complex traits and diseases, those genetic variants typically explain only a small fraction of phenotypic variance. Factors that account for phenotypic variance include environmental factors and gene-by-environment interactions (GEIs). Recently, several studies have conducted genome-wide gene-by-environment association analyses and demonstrated important roles of GEIs in complex traits. One of the main challenges in these association studies is to control effects of population structure that may cause spurious associations. Many studies have analyzed how population structure influences statistics of genetic variants and developed several statistical approaches to correct for population structure. However, the impact of population structure on GEI statistics in GWASs has not been extensively studied and nor have there been methods designed to correct for population structure on GEI statistics. In this paper, we show both analytically and empirically that population structure may cause spurious GEIs and use both simulation and two GWAS datasets to support our finding. We propose a statistical approach based on mixed models to account for population structure on GEI statistics. We find that our approach effectively controls population structure on statistics for GEIs as well as for genetic variants
On Population Structure and Marriage Dynamics
I develop an equilibrium, two-sided search model of marriage with endogenous population growth to study the interaction between fertility, the age structure of the population and the age at first marriage of men and women. Within a simple two-period overlapping generation model I show that, given an increase of the desired number of children, age at marriage is affected through two different channels. First, as population growth increases, the age structure of the population produces a thicker market for young people, inducing early marriages. The second channel comes from differential fecundity: if the desired number of children is not feasible for older women, women tend to marry younger and men older, with single men outnumbering single women in equilibrium. Using an extended version of the model to a finite number of periods and fertility data, I show that two mechanisms described above may have acted as persistence mechanisms after the U.S “baby boom”. I show that demographic transitional dynamics after the baby boom may account for approximately a 23% of the increase in men's age of marriage between 1985 and 2009, albeit the impact on women's age is small.population structure, marriage, search
The stellar population structure of the Galactic disk
The spatial structure of stellar populations with different chemical
abundances in the Milky Way contains a wealth of information on Galactic
evolution over cosmic time. We use data on 14,699 red-clump stars from the
APOGEE survey, covering 4 kpc <~ R <~ 15 kpc, to determine the structure of
mono-abundance populations (MAPs)---stars in narrow bins in [a/Fe] and
[Fe/H]---accounting for the complex effects of the APOGEE selection function
and the spatially-variable dust obscuration. We determine that all MAPs with
enhanced [a/Fe] are centrally concentrated and are well-described as
exponentials with a scale length of 2.2+/-0.2 kpc over the whole radial range
of the disk. We discover that the surface-density profiles of low-[a/Fe] MAPs
are complex: they do not monotonically decrease outwards, but rather display a
peak radius ranging from ~5 kpc to ~13 kpc at low [Fe/H]. The extensive radial
coverage of the data allows us to measure radial trends in the thickness of
each MAP. While high-[a/Fe] MAPs have constant scale heights, low-[a/Fe] MAPs
flare. We confirm, now with high-precision abundances, previous results that
each MAP contains only a single vertical scale height and that low-[Fe/H],
low-[a/Fe] and high-[Fe/H], high-[a/Fe] MAPs have intermediate (h_Z~300 to 600
pc) scale heights that smoothly bridge the traditional thin- and thick-disk
divide. That the high-[a/Fe], thick disk components do not flare is strong
evidence against their thickness being caused by radial migration. The
correspondence between the radial structure and chemical-enrichment age of
stellar populations is clear confirmation of the inside-out growth of galactic
disks. The details of these relations will constrain the variety of physical
conditions under which stars form throughout the MW disk.Comment: Code available at https://github.com/jobovy/apogee-map
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