TIDieR-PHP: a reporting guideline for population health and policy interventions

We lack guidance on how to describe population health and policy (PHP) interventions in reports of evaluation studies. PHP interventions are legal, fiscal, structural, organisational, environmental, and policy interventions such as the regulation of unhealthy commodities, health service reorganisation, changes in welfare policy, and neighbourhood improvement schemes. Many PHP interventions have characteristics that are important for their implementation and success but are not adequately captured in the original Template for Intervention Description and Replication (TIDieR) checklist. This article describes the development of a revised reporting template for PHP interventions (TIDieR-PHP) and presents the checklist with examples for each ite

Using R via PHP for Teaching Purposes: R-php

This paper deals with the R-php statistical software, that is an environment for statistical analysis, freely accessible and attainable through the World Wide Web, based on R. Indeed, this software uses, as "engine" for statistical analyses, R via PHP and its design has been inspired by a paper of de Leeuw (1997). R-php is based on two modules: a base module and a point-and-click module. R-php base allows the simple editing of R code in a form. R-php point-and-click allows some statistical analyses by means of a graphical user interface (GUI): then, to use this module it is not necessary for the user to know the R environment, but all the allowed analyses can be performed by using the computer mouse. We think that this tool could be particularly useful for teaching purposes: one possible use could be in a University computer laboratory to permit a smooth approach of students to R.

Inclusive Jets in PHP

Differential inclusive-jet cross sections have been measured in photoproduction for boson virtualities Q^2 < 1 GeV^2 with the ZEUS detector at HERA using an integrated luminosity of 300 pb^-1. Jets were identified in the laboratory frame using the k_T, anti-k_T or SIScone jet algorithms. Cross sections are presented as functions of the jet pseudorapidity, eta(jet), and the jet transverse energy, E_T(jet). Next-to-leading-order QCD calculations give a good description of the measurements, except for jets with low E_T(jet) and high eta(jet). The cross sections have the potential to improve the determination of the PDFs in future QCD fits. Values of alpha_s(M_Z) have been extracted from the measurements based on different jet algorithms. In addition, the energy-scale dependence of the strong coupling was determined.Comment: To appear in the proceedings of the EPS HEP 2013 conferenc

Tight Lower Bounds on the Contact Distance Distribution in Poisson Hole Process

In this letter, we derive new lower bounds on the cumulative distribution function (CDF) of the contact distance in the Poisson Hole Process (PHP) for two cases: (i) reference point is selected uniformly at random from $\mathbb{R}^2$ independently of the PHP, and (ii) reference point is located at the center of a hole selected uniformly at random from the PHP. While one can derive upper bounds on the CDF of contact distance by simply ignoring the effect of holes, deriving lower bounds is known to be relatively more challenging. As a part of our proof, we introduce a tractable way of bounding the effect of all the holes in a PHP, which can be used to study other properties of a PHP as well.Comment: To appear in IEEE Wireless Communications Letter

MCTP is an ER-resident calcium sensor that stabilizes synaptic transmission and homeostatic plasticity.

Presynaptic homeostatic plasticity (PHP) controls synaptic transmission in organisms from Drosophila to human and is hypothesized to be relevant to the cause of human disease. However, the underlying molecular mechanisms of PHP are just emerging and direct disease associations remain obscure. In a forward genetic screen for mutations that block PHP we identified mctp (Multiple C2 Domain Proteins with Two Transmembrane Regions). Here we show that MCTP localizes to the membranes of the endoplasmic reticulum (ER) that elaborate throughout the soma, dendrites, axon and presynaptic terminal. Then, we demonstrate that MCTP functions downstream of presynaptic calcium influx with separable activities to stabilize baseline transmission, short-term release dynamics and PHP. Notably, PHP specifically requires the calcium coordinating residues in each of the three C2 domains of MCTP. Thus, we propose MCTP as a novel, ER-localized calcium sensor and a source of calcium-dependent feedback for the homeostatic stabilization of neurotransmission

New insights into the structure of early-type galaxies: the Photometric Plane at z~0.3

We study the Photometric Plane (PHP), namely the relation between the effective radius re, the mean surface brightness within that radius e, and the Sersic index n, in optical (R and I) and near-infrared (K) bands for a large sample of early-type galaxies (ETGs) in the rich cluster MS1008-1224 at z=0.306. The PHP relation has an intrinsic dispersion of ~32% in re, and turns out to be independent of waveband. This result is consistent with the fact that internal colour gradients of ETGs can have only a mild dependence on galaxy luminosity (mass). There is no evidence for a significant curvature in the PHP. We show that this can be explained if this relation origins from a systematic variation of the specific entropy of ETGs along the galaxy sequence, as was suggested from previous works. The intrinsic scatter of the PHP is significantly smaller than for other purely photometric relations, such as the Kormendy relation and the photometric Fundamental Plane, which is constructed by using colours in place of velocity dispersions. The scatter does not depend on the waveband and the residuals about the plane do not correlate with residuals of the colour-magnitude relation. Finally, we compare the coefficients of the PHP at z~0.3 with those of ETGs at z~0, showing that the PHP is a valuable tool to constrain the luminosity evolution of ETGs with redshift. The slopes of the PHP do not change significantly with redshift, while the zero-point is consistent with cosmological dimming of the surface brightness in an expanding universe plus the passive fading of galaxy stellar populations with a high formation redshift (z_f >1-2).Comment: 21 pages, 10 figures, MNRAS in pres

Processing Posting Lists Using OpenCL

One of the main requirements of internet search engines is the ability to retrieve relevant results with faster response times. Yioop is an open source search engine designed and developed in PHP by Dr. Chris Pollett. The goal of this project is to explore the possibilities of enhancing the performance of Yioop by substituting resource-intensive existing PHP functions with C based native PHP extensions and the parallel data processing technology OpenCL. OpenCL leverages the Graphical Processing Unit (GPU) of a computer system for performance improvements. Some of the critical functions in search engines are resource-intensive in terms of processing power, memory, and I/O usage. The processing times vary based on the complexity and magnitude of data involved. This project involves different phases such as identifying critical resource intensive functions, initially replacing such methods with PHP Extensions, and eventually experimenting with OpenCL code. We also ran performance tests to measure the reduction in processing times. From our results, we concluded that PHP Extensions and OpenCL processing resulted in performance improvements

Three manifestations of the pulsed harmonic potential

We consider, in turn, three systems being acted upon by a regularly pulsed harmonic potential (PHP). These are i) a classical particle, ii) a quantum particle, and iii) a directed line. We contrast the mechanics of the first two systems by parameterizing their bands of stability and periodicity. Interesting differences due to quantum fluctuations are examined in detail. The fluctuations of the directed line are calculated in the two cases of a binding PHP, and an unbinding PHP. In the latter case there is a finite maximum line length for a given potential strength.Comment: 34 Revtex pages, with 5 attached figure

Molecular mechanisms that stabilize short term synaptic plasticity during presynaptic homeostatic plasticity.

Presynaptic homeostatic plasticity (PHP) compensates for impaired postsynaptic neurotransmitter receptor function through a rapid, persistent adjustment of neurotransmitter release, an effect that can exceed 200%. An unexplained property of PHP is the preservation of short-term plasticity (STP), thereby stabilizing activity-dependent synaptic information transfer. We demonstrate that the dramatic potentiation of presynaptic release during PHP is achieved while simultaneously maintaining a constant ratio of primed to super-primed synaptic vesicles, thereby preserving STP. Mechanistically, genetic, biochemical and electrophysiological evidence argue that a constant ratio of primed to super-primed synaptic vesicles is achieved by the concerted action of three proteins: Unc18, Syntaxin1A and RIM. Our data support a model based on the regulated availability of Unc18 at the presynaptic active zone, a process that is restrained by Syntaxin1A and facilitated by RIM. As such, regulated vesicle priming/super-priming enables PHP to stabilize both synaptic gain and the activity-dependent transfer of information at a synapse