4 research outputs found
Overview of Computational Approaches for Inference of MicroRNA-Mediated and Gene Regulatory Networks
Overview of Computational Approaches for Inference of MicroRNA-Mediated and Gene Regulatory Networks
Introduction to RNAi and miRNA pathways
Dráhy malĂ˝ch RNA jsou skupinou drah vyuĹľĂvajĂcĂch malĂ© RNA k sekvenÄŤnÄ› specifickĂ© represi. Tento soubor ÄŤlánkĹŻ o drahách malĂ˝ch RNA má pĹŻvod ve zprávÄ› vypracovanĂ© pro European Food and Safety Authority (EFSA) v letech 2016 a 2017. Text byl novÄ› rozÄŤlenÄ›n do dvanácti kapitol a doplnÄ›n Ăşvody; vypuštÄ›n byl naopak materiál podlĂ©hajĂcĂ autorskĂ©mu právu tĹ™etĂch stran. DevÄ›t kapitol je vÄ›nováno drahám malĂ˝ch RNA ve zvĂĹ™atech a rostlinách, zbĂ˝vajĂcĂ tĹ™i pĹ™ipadajĂ na obecnĂ˝ Ăşvod a problematiku extracelulárnĂ RNA.Small RNA pathways or RNA silencing is a group of pathways, which utilize small RNAs as guides for sequence-specific repression. This collection of texts has an origin in a report prepared for the EFSA in 2016 and 2017. The original text was reorganized into twelve chapters, which were reformatted and revised in order to remove copyrighted material from third parties and provide a introductory parts for stand alone chapters. Nine of the chapters focus on small RNA pathways in animals and plants. The remaining three chapters include a general introduction and reviews of important phenomena – off-targeting and extracellular small RNAs