Constraining the Number of Positive Responses in Adaptive, Non-Adaptive, and Two-Stage Group Testing

Group testing is a well known search problem that consists in detecting the defective members of a set of objects O by performing tests on properly chosen subsets (pools) of the given set O. In classical group testing the goal is to find all defectives by using as few tests as possible. We consider a variant of classical group testing in which one is concerned not only with minimizing the total number of tests but aims also at reducing the number of tests involving defective elements. The rationale behind this search model is that in many practical applications the devices used for the tests are subject to deterioration due to exposure to or interaction with the defective elements. In this paper we consider adaptive, non-adaptive and two-stage group testing. For all three considered scenarios, we derive upper and lower bounds on the number of "yes" responses that must be admitted by any strategy performing at most a certain number t of tests. In particular, for the adaptive case we provide an algorithm that uses a number of "yes" responses that exceeds the given lower bound by a small constant. Interestingly, this bound can be asymptotically attained also by our two-stage algorithm, which is a phenomenon analogous to the one occurring in classical group testing. For the non-adaptive scenario we give almost matching upper and lower bounds on the number of "yes" responses. In particular, we give two constructions both achieving the same asymptotic bound. An interesting feature of one of these constructions is that it is an explicit construction. The bounds for the non-adaptive and the two-stage cases follow from the bounds on the optimal sizes of new variants of d-cover free families and (p,d)-cover free families introduced in this paper, which we believe may be of interest also in other contexts

Superselectors: Efficient Constructions and Applications

We introduce a new combinatorial structure: the superselector. We show that superselectors subsume several important combinatorial structures used in the past few years to solve problems in group testing, compressed sensing, multi-channel conflict resolution and data security. We prove close upper and lower bounds on the size of superselectors and we provide efficient algorithms for their constructions. Albeit our bounds are very general, when they are instantiated on the combinatorial structures that are particular cases of superselectors (e.g., (p,k,n)-selectors, (d,\ell)-list-disjunct matrices, MUT_k(r)-families, FUT(k, a)-families, etc.) they match the best known bounds in terms of size of the structures (the relevant parameter in the applications). For appropriate values of parameters, our results also provide the first efficient deterministic algorithms for the construction of such structures

A single-photon sampling architecture for solid-state imaging

Advances in solid-state technology have enabled the development of silicon photomultiplier sensor arrays capable of sensing individual photons. Combined with high-frequency time-to-digital converters (TDCs), this technology opens up the prospect of sensors capable of recording with high accuracy both the time and location of each detected photon. Such a capability could lead to significant improvements in imaging accuracy, especially for applications operating with low photon fluxes such as LiDAR and positron emission tomography. The demands placed on on-chip readout circuitry imposes stringent trade-offs between fill factor and spatio-temporal resolution, causing many contemporary designs to severely underutilize the technology's full potential. Concentrating on the low photon flux setting, this paper leverages results from group testing and proposes an architecture for a highly efficient readout of pixels using only a small number of TDCs, thereby also reducing both cost and power consumption. The design relies on a multiplexing technique based on binary interconnection matrices. We provide optimized instances of these matrices for various sensor parameters and give explicit upper and lower bounds on the number of TDCs required to uniquely decode a given maximum number of simultaneous photon arrivals. To illustrate the strength of the proposed architecture, we note a typical digitization result of a 120x120 photodiode sensor on a 30um x 30um pitch with a 40ps time resolution and an estimated fill factor of approximately 70%, using only 161 TDCs. The design guarantees registration and unique recovery of up to 4 simultaneous photon arrivals using a fast decoding algorithm. In a series of realistic simulations of scintillation events in clinical positron emission tomography the design was able to recover the spatio-temporal location of 98.6% of all photons that caused pixel firings.Comment: 24 pages, 3 figures, 5 table

Uniform hypergraphs containing no grids

A hypergraph is called an r×r grid if it is isomorphic to a pattern of r horizontal and r vertical lines, i.e.,a family of sets {A1, ..., Ar, B1, ..., Br} such that Ai∩Aj=Bi∩Bj=φ for 1≤i<j≤r and {pipe}Ai∩Bj{pipe}=1 for 1≤i, j≤r. Three sets C1, C2, C3 form a triangle if they pairwise intersect in three distinct singletons, {pipe}C1∩C2{pipe}={pipe}C2∩C3{pipe}={pipe}C3∩C1{pipe}=1, C1∩C2≠C1∩C3. A hypergraph is linear, if {pipe}E∩F{pipe}≤1 holds for every pair of edges E≠F.In this paper we construct large linear r-hypergraphs which contain no grids. Moreover, a similar construction gives large linear r-hypergraphs which contain neither grids nor triangles. For r≥. 4 our constructions are almost optimal. These investigations are motivated by coding theory: we get new bounds for optimal superimposed codes and designs. © 2013 Elsevier Ltd

Asymptotic Error Free Partitioning over Noisy Boolean Multiaccess Channels

In this paper, we consider the problem of partitioning active users in a manner that facilitates multi-access without collision. The setting is of a noisy, synchronous, Boolean, multi-access channel where $K$ active users (out of a total of $N$ users) seek to access. A solution to the partition problem places each of the $N$ users in one of $K$ groups (or blocks) such that no two active nodes are in the same block. We consider a simple, but non-trivial and illustrative case of $K=2$ active users and study the number of steps $T$ used to solve the partition problem. By random coding and a suboptimal decoding scheme, we show that for any $T\geq (C_1 +\xi_1)\log N$, where $C_1$ and $\xi_1$ are positive constants (independent of $N$), and $\xi_1$ can be arbitrary small, the partition problem can be solved with error probability $P_e^{(N)} \to 0$, for large $N$. Under the same scheme, we also bound $T$ from the other direction, establishing that, for any $T \leq (C_2 - \xi_2) \log N$, the error probability $P_e^{(N)} \to 1$ for large $N$; again $C_2$ and $\xi_2$ are constants and $\xi_2$ can be arbitrarily small. These bounds on the number of steps are lower than the tight achievable lower-bound in terms of $T \geq (C_g +\xi)\log N$ for group testing (in which all active users are identified, rather than just partitioned). Thus, partitioning may prove to be a more efficient approach for multi-access than group testing.Comment: This paper was submitted in June 2014 to IEEE Transactions on Information Theory, and is under review no