One-shot Learning for iEEG Seizure Detection Using End-to-end Binary Operations: Local Binary Patterns with Hyperdimensional Computing

This paper presents an efficient binarized algorithm for both learning and classification of human epileptic seizures from intracranial electroencephalography (iEEG). The algorithm combines local binary patterns with brain-inspired hyperdimensional computing to enable end-to-end learning and inference with binary operations. The algorithm first transforms iEEG time series from each electrode into local binary pattern codes. Then atomic high-dimensional binary vectors are used to construct composite representations of seizures across all electrodes. For the majority of our patients (10 out of 16), the algorithm quickly learns from one or two seizures (i.e., one-/few-shot learning) and perfectly generalizes on 27 further seizures. For other patients, the algorithm requires three to six seizures for learning. Overall, our algorithm surpasses the state-of-the-art methods for detecting 65 novel seizures with higher specificity and sensitivity, and lower memory footprint.Comment: Published as a conference paper at the IEEE BioCAS 201

SeizureNet: Multi-Spectral Deep Feature Learning for Seizure Type Classification

Automatic classification of epileptic seizure types in electroencephalograms (EEGs) data can enable more precise diagnosis and efficient management of the disease. This task is challenging due to factors such as low signal-to-noise ratios, signal artefacts, high variance in seizure semiology among epileptic patients, and limited availability of clinical data. To overcome these challenges, in this paper, we present SeizureNet, a deep learning framework which learns multi-spectral feature embeddings using an ensemble architecture for cross-patient seizure type classification. We used the recently released TUH EEG Seizure Corpus (V1.4.0 and V1.5.2) to evaluate the performance of SeizureNet. Experiments show that SeizureNet can reach a weighted F1 score of up to 0.94 for seizure-wise cross validation and 0.59 for patient-wise cross validation for scalp EEG based multi-class seizure type classification. We also show that the high-level feature embeddings learnt by SeizureNet considerably improve the accuracy of smaller networks through knowledge distillation for applications with low-memory constraints

Epilepsy attacks recognition based on 1D octal pattern, wavelet transform and EEG signals

Electroencephalogram (EEG) signals have been generally utilized for diagnostic systems. Nowadays artificial intelligence-based systems have been proposed to classify EEG signals to ease diagnosis process. However, machine learning models have generally been used deep learning based classification model to reach high classification accuracies. This work focuses classification epilepsy attacks using EEG signals with a lightweight and simple classification model. Hence, an automated EEG classification model is presented. The used phases of the presented automated EEG classification model are (i) multileveled feature generation using one-dimensional (1D) octal-pattern (OP) and discrete wavelet transform (DWT). Here, main feature generation function is the presented octal-pattern. DWT is employed for level creation. By employing DWT frequency coefficients of the EEG signal is obtained and octal-pattern generates texture features from raw EEG signal and wavelet coefficients. This DWT and octal-pattern based feature generator extracts 128 × 8 = 1024 (Octal-pattern generates 128 features from a signal, 8 signal are used in the feature generation 1 raw EEG and 7 wavelet low-pass filter coefficients). (ii) To select the most useful features, neighborhood component analysis (NCA) is deployed and 128 features are selected. (iii) The selected features are feed to k nearest neighborhood classifier. To test this model, an epilepsy seizure dataset is used and 96.0% accuracy is attained for five categories. The results clearly denoted the success of the presented octal-pattern based epilepsy classification model

Effective electroencephalogram based epileptic seizure detection using support vector machine and statistical moment’s features

Epilepsy is one of the widespread disorders. It is a noncommunicable disease that affects the human nerve system. Seizures are abnormal patterns of behavior in the electricity of the brain which produce symptoms like losing consciousness, attention or convulsions in the whole body. This paper demonstrates an effective electroencephalogram (EEG) based seizure detection method using discrete wavelet transformation (DWT) for signal decomposition to extract features. An automatic channel selection method was proposed by the researcher to select the best channel from 23 channels based on maximum variance value. The records were segmented into a nonoverlapping segment with long 1-S. The support vector machine (SVM) model was used to automatically detect segments that contain seizures, using both frequency and time domain statistical moment features. The experimental result was obtained from 24 patients in CHB-MIT database. The average accuracy is 94.1, sensitivity is 93.5, specificity is 94.6 and the false positive rate average is 0.054

EEG sleep stages identification based on weighted undirected complex networks

Sleep scoring is important in sleep research because any errors in the scoring of the patient's sleep electroencephalography (EEG) recordings can cause serious problems such as incorrect diagnosis, medication errors, and misinterpretations of patient's EEG recordings. The aim of this research is to develop a new automatic method for EEG sleep stages classification based on a statistical model and weighted brain networks. Methods each EEG segment is partitioned into a number of blocks using a sliding window technique. A set of statistical features are extracted from each block. As a result, a vector of features is obtained to represent each EEG segment. Then, the vector of features is mapped into a weighted undirected network. Different structural and spectral attributes of the networks are extracted and forwarded to a least square support vector machine (LS-SVM) classifier. At the same time the network's attributes are also thoroughly investigated. It is found that the network's characteristics vary with their sleep stages. Each sleep stage is best represented using the key features of their networks. Results In this paper, the proposed method is evaluated using two datasets acquired from different channels of EEG (Pz-Oz and C3-A2) according to the R&K and the AASM without pre-processing the original EEG data. The obtained results by the LS-SVM are compared with those by Naïve, k-nearest and a multi-class-SVM. The proposed method is also compared with other benchmark sleep stages classification methods. The comparison results demonstrate that the proposed method has an advantage in scoring sleep stages based on single channel EEG signals. Conclusions An average accuracy of 96.74% is obtained with the C3-A2 channel according to the AASM standard, and 96% with the Pz-Oz channel based on the R&K standard

Deep learning approach for epileptic seizure detection

Abstract. Epilepsy is the most common brain disorder that affects approximately fifty million people worldwide, according to the World Health Organization. The diagnosis of epilepsy relies on manual inspection of EEG, which is error-prone and time-consuming. Automated epileptic seizure detection of EEG signal can reduce the diagnosis time and facilitate targeting of treatment for patients. Current detection approaches mainly rely on the features that are designed manually by domain experts. The features are inflexible for the detection of a variety of complex patterns in a large amount of EEG data. Moreover, the EEG is non-stationary signal and seizure patterns vary across patients and recording sessions. EEG data always contain numerous noise types that negatively affect the detection accuracy of epileptic seizures. To address these challenges deep learning approaches are examined in this paper. Deep learning methods were applied to a large publicly available dataset, the Children’s Hospital of Boston-Massachusetts Institute of Technology dataset (CHB-MIT). The present study includes three experimental groups that are grouped based on the pre-processing steps. The experimental groups contain 3–4 experiments that differ between their objectives. The time-series EEG data is first pre-processed by certain filters and normalization techniques, and then the pre-processed signal was segmented into a sequence of non-overlapping epochs. Second, time series data were transformed into different representations of input signals. In this study time-series EEG signal, magnitude spectrograms, 1D-FFT, 2D-FFT, 2D-FFT magnitude spectrum and 2D-FFT phase spectrum were investigated and compared with each other. Third, time-domain or frequency-domain signals were used separately as a representation of input data of VGG or DenseNet 1D. The best result was achieved with magnitude spectrograms used as representation of input data in VGG model: accuracy of 0.98, sensitivity of 0.71 and specificity of 0.998 with subject dependent data. VGG along with magnitude spectrograms produced promising results for building personalized epileptic seizure detector. There was not enough data for VGG and DenseNet 1D to build subject-dependent classifier.Epileptisten kohtausten havaitseminen syväoppimisella lähestymistavalla. Tiivistelmä. Epilepsia on yleisin aivosairaus, joka Maailman terveysjärjestön mukaan vaikuttaa noin viiteenkymmeneen miljoonaan ihmiseen maailmanlaajuisesti. Epilepsian diagnosointi perustuu EEG:n manuaaliseen tarkastamiseen, mikä on virhealtista ja aikaa vievää. Automaattinen epileptisten kohtausten havaitseminen EEG-signaalista voi potentiaalisesti vähentää diagnoosiaikaa ja helpottaa potilaan hoidon kohdentamista. Nykyiset tunnistusmenetelmät tukeutuvat pääasiassa piirteisiin, jotka asiantuntijat ovat määritelleet manuaalisesti, mutta ne ovat joustamattomia monimutkaisten ilmiöiden havaitsemiseksi suuresta määrästä EEG-dataa. Lisäksi, EEG on epästationäärinen signaali ja kohtauspiirteet vaihtelevat potilaiden ja tallennusten välillä ja EEG-data sisältää aina useita kohinatyyppejä, jotka huonontavat epilepsiakohtauksen havaitsemisen tarkkuutta. Näihin haasteisiin vastaamiseksi tässä diplomityössä tarkastellaan soveltuvatko syväoppivat menetelmät epilepsian havaitsemiseen EEG-tallenteista. Aineistona käytettiin suurta julkisesti saatavilla olevaa Bostonin Massachusetts Institute of Technology lastenklinikan tietoaineistoa (CHB-MIT). Tämän työn tutkimus sisältää kolme koeryhmää, jotka eroavat toisistaan esikäsittelyvaiheiden osalta: aikasarja-EEG-data esikäsiteltiin perinteisten suodattimien ja normalisointitekniikoiden avulla, ja näin esikäsitelty signaali segmentoitiin epookkeihin. Kukin koeryhmä sisältää 3–4 koetta, jotka eroavat menetelmiltään ja tavoitteiltaan. Kussakin niistä epookkeihin jaettu aikasarjadata muutettiin syötesignaalien erilaisiksi esitysmuodoiksi. Tässä tutkimuksessa tutkittiin ja verrattiin keskenään EEG-signaalia sellaisenaan, EEG-signaalin amplitudi-spektrogrammeja, 1D-FFT-, 2D-FFT-, 2D-FFT-amplitudi- ja 2D-FFT -vaihespektriä. Näin saatuja aika- ja taajuusalueen signaaleja käytettiin erikseen VGG- tai DenseNet 1D -mallien syötetietoina. Paras tulos saatiin VGG-mallilla kun syötetietona oli amplitudi-spektrogrammi ja tällöin tarkkuus oli 0,98, herkkyys 0,71 ja spesifisyys 0,99 henkilöstä riippuvaisella EEG-datalla. VGG yhdessä amplitudi-spektrogrammien kanssa tuottivat lupaavia tuloksia henkilökohtaisen epilepsiakohtausdetektorin rakentamiselle. VGG- ja DenseNet 1D -malleille ei ollut tarpeeksi EEG-dataa henkilöstä riippumattoman luokittelijan opettamiseksi

Comparison of EEG based epilepsy diagnosis using neural networks and wavelet transform

Epilepsy is one of the common neurological disorders characterized by recurrent and uncontrollable seizures, which seriously affect the life of patients. In many cases, electroencephalograms signal can provide important physiological information about the activity of the human brain which can be used to diagnose epilepsy. However, visual inspection of a large number of electroencephalogram signals is very time-consuming and can often lead to inconsistencies in physicians' diagnoses. Quantification of abnormalities in brain signals can indicate brain conditions and pathology so the electroencephalogram (EEG) signal plays a key role in the diagnosis of epilepsy. In this article, an attempt has been made to create a single instruction for diagnosing epilepsy, which consists of two steps. In the first step, a low-pass filter was used to preprocess the data and three separate mid-pass filters for different frequency bands and a multilayer neural network were designed. In the second step, the wavelet transform technique was used to process data. In particular, this paper proposes a multilayer perceptron neural network classifier for the diagnosis of epilepsy, that requires normal data and epilepsy data for education, but this classifier can recognize normal disorders, epilepsy, and even other disorders taught in educational examples. Also, the value of using electroencephalogram signal has been evaluated in two ways: using wavelet transform and non-using wavelet transform. Finally, the evaluation results indicate a relatively uniform impact factor on the use or non-use of wavelet transform on the improvement of epilepsy data functions, but in the end, it was shown that the use of perceptron multilayer neural network can provide a higher accuracy coefficient for experts.Comment: 8 pages, 4 tables, 3 figure