Prediction of Computer Vision Syndrome in Health Personnel by Means of Genetic Algorithms and Binary Regression Trees

One of the major consequences of the digital revolution has been the increase in the use of electronic devices in health services. Despite their remarkable advantages, though, the use of computers and other visual display terminals for a prolonged time may have negative effects on vision, leading to a greater risk of Computer Vision Syndrome (CVS) among their users. In this study, the importance of ocular and visual symptoms related to CVS was evaluated, and the factors associated with CVS were studied, with the help of an algorithm based on regression trees and genetic algorithms. The performance of this proposed model was also tested to check its ability to predict how prone a worker is to suffering from CVS. The findings of the present research confirm a high prevalence of CVS in healthcare workers, and associate CVS with a longer duration of occupation and higher daily computer usage

Understanding Health and Disease with Multidimensional Single-Cell Methods

Current efforts in the biomedical sciences and related interdisciplinary fields are focused on gaining a molecular understanding of health and disease, which is a problem of daunting complexity that spans many orders of magnitude in characteristic length scales, from small molecules that regulate cell function to cell ensembles that form tissues and organs working together as an organism. In order to uncover the molecular nature of the emergent properties of a cell, it is essential to measure multiple cell components simultaneously in the same cell. In turn, cell heterogeneity requires multiple cells to be measured in order to understand health and disease in the organism. This review summarizes current efforts towards a data-driven framework that leverages single-cell technologies to build robust signatures of healthy and diseased phenotypes. While some approaches focus on multicolor flow cytometry data and other methods are designed to analyze high-content image-based screens, we emphasize the so-called Supercell/SVM paradigm (recently developed by the authors of this review and collaborators) as a unified framework that captures mesoscopic-scale emergence to build reliable phenotypes. Beyond their specific contributions to basic and translational biomedical research, these efforts illustrate, from a larger perspective, the powerful synergy that might be achieved from bringing together methods and ideas from statistical physics, data mining, and mathematics to solve the most pressing problems currently facing the life sciences.Comment: 25 pages, 7 figures; revised version with minor changes. To appear in J. Phys.: Cond. Mat

Application of Artificial Intelligence in Modern Healthcare System

Artificial intelligence (AI) has the potential of detecting significant interactions in a dataset and also it is widely used in several clinical conditions to expect the results, treat, and diagnose. Artificial intelligence (AI) is being used or trialed for a variety of healthcare and research purposes, including detection of disease, management of chronic conditions, delivery of health services, and drug discovery. In this chapter, we will discuss the application of artificial intelligence (AI) in modern healthcare system and the challenges of this system in detail. Different types of artificial intelligence devices are described in this chapter with the help of working mechanism discussion. Alginate, a naturally available polymer found in the cell wall of the brown algae, is used in tissue engineering because of its biocompatibility, low cost, and easy gelation. It is composed of α-L-guluronic and β-D-manuronic acid. To improve the cell-material interaction and erratic degradation, alginate is blended with other polymers. Here, we discuss the relationship of artificial intelligence with alginate in tissue engineering fields

Towards a cyber physical system for personalised and automatic OSA treatment

Obstructive sleep apnea (OSA) is a breathing disorder that takes place in the course of the sleep and is produced by a complete or a partial obstruction of the upper airway that manifests itself as frequent breathing stops and starts during the sleep. The real-time evaluation of whether or not a patient is undergoing OSA episode is a very important task in medicine in many scenarios, as for example for making instantaneous pressure adjustments that should take place when Automatic Positive Airway Pressure (APAP) devices are used during the treatment of OSA. In this paper the design of a possible Cyber Physical System (CPS) suited to real-time monitoring of OSA is described, and its software architecture and possible hardware sensing components are detailed. It should be emphasized here that this paper does not deal with a full CPS, rather with a software part of it under a set of assumptions on the environment. The paper also reports some preliminary experiments about the cognitive and learning capabilities of the designed CPS involving its use on a publicly available sleep apnea database

Aerospace medicine and biology: A continuing bibliography with indexes (supplement 323)

This bibliography lists 125 reports, articles and other documents introduced into the NASA Scientific and Technical Information System during April, 1989. Subject coverage includes; aerospace medicine and psychology, life support systems and controlled environments, safety equipment exobiology and extraterrestrial life, and flight crew behavior and performance

Quantifying The Effects of Biomarkers and Comorbidities in Predicting SARS Cov-2 Associated Mortality in Hospitalized Patients in Mexico

In this retrospective quasi-experimental, cohort study, the biomarkers, demographics, and clinical characteristics of the adult inpatients with laboratory-confirmed COVID-19 from Hospital Regional 110 (Guadalajara, Mexico) were analyzed who were hospitalized over the year 2020, between April 15 (i.e. when the first patient was admitted) to December 31 and had a definite outcome (discharged or dead), to establish the most important variables for the models. In this study, 5 different Classifiers were used: Random Forest, Support Vector Machine, XGBoost, Naïves Bayes, and Symbolic Classifier to classify the outcome of the patients and also to quantify the effect of biomarkers and comorbidities in predicting SARS-CoV-2 positive associated mortality in hospitalized patients. Also, the Symbolic Transofmer was implemented to try to improve the performance of our model. As the dataset includes a big percentage of missing values, we proposed two models, one excluding the missing values and the other including all the missing values. The Random Forest was implemented to obtain the variable importance, and also to the capacity of the model to handle the missing values. The metrics ROC AUC and Accuracy were used to train the models, along with the Bayesian Optimization to tune the hyperparameters and to measure the performance

Facial feature representation and recognition

Facial expression provides an important behavioral measure for studies of emotion, cognitive processes, and social interaction. Facial expression representation and recognition have become a promising research area during recent years. Its applications include human-computer interfaces, human emotion analysis, and medical care and cure. In this dissertation, the fundamental techniques will be first reviewed, and the developments of the novel algorithms and theorems will be presented later. The objective of the proposed algorithm is to provide a reliable, fast, and integrated procedure to recognize either seven prototypical, emotion-specified expressions (e.g., happy, neutral, angry, disgust, fear, sad, and surprise in JAFFE database) or the action units in CohnKanade AU-coded facial expression image database. A new application area developed by the Infant COPE project is the recognition of neonatal facial expressions of pain (e.g., air puff, cry, friction, pain, and rest in Infant COPE database). It has been reported in medical literature that health care professionals have difficulty in distinguishing newborn\u27s facial expressions of pain from facial reactions of other stimuli. Since pain is a major indicator of medical problems and the quality of patient care depends on the quality of pain management, it is vital that the methods to be developed should accurately distinguish an infant\u27s signal of pain from a host of minor distress signal. The evaluation protocol used in the Infant COPE project considers two conditions: person-dependent and person-independent. The person-dependent means that some data of a subject are used for training and other data of the subject for testing. The person-independent means that the data of all subjects except one are used for training and this left-out one subject is used for testing. In this dissertation, both evaluation protocols are experimented. The Infant COPE research of neonatal pain classification is a first attempt at applying the state-of-the-art face recognition technologies to actual medical problems. The objective of Infant COPE project is to bypass these observational problems by developing a machine classification system to diagnose neonatal facial expressions of pain. Since assessment of pain by machine is based on pixel states, a machine classification system of pain will remain objective and will exploit the full spectrum of information available in a neonate\u27s facial expressions. Furthermore, it will be capable of monitoring neonate\u27s facial expressions when he/she is left unattended. Experimental results using the Infant COPE database and evaluation protocols indicate that the application of face classification techniques in pain assessment and management is a promising area of investigation. One of the challenging problems for building an automatic facial expression recognition system is how to automatically locate the principal facial parts since most existing algorithms capture the necessary face parts by cropping images manually. In this dissertation, two systems are developed to detect facial features, especially for eyes. The purpose is to develop a fast and reliable system to detect facial features automatically and correctly. By combining the proposed facial feature detection, the facial expression and neonatal pain recognition systems can be robust and efficient

Predictive analytics in agribusiness industries

Agriculturally related industries are routinely among the most hazardous work environments. Workplace injuries directly impact labor-market outcomes including income reduction, job loss, and health of the injured workers. In addition to medical and indemnity costs, workplace incidents include indirect costs such as equipment damage and repair, incident investigation time, training new personnel for replacement of the injured ones, an increase in insurance premiums for the year following the incidents, a slowdown of production schedules, damage to companies’ reputation, and lowering the workers’ motivation to return to work. The main purpose of incident analysis is the derivation and development of preventative measures from injury data. Applying proper analytical tools aimed at discovering the causes of occupational incidents is essential to gain useful information that contributes in preventing those incidents in future. Insight gained from the analyses of workers’ compensation data can efficiently direct preventative activities at high-risk industries. Since incidents arise from a combination of factors rather than a single cause, research on occupational incidents must go deeper into identifying the underlying causes and their relationship through applying more comprehensive analyses. Therefore, this study aimed at identifying underlying patterns in occupational injury occurrence and costs using data mining and predictive modeling techniques instead of traditional statistical methods. Utilizing a workers’ compensation claims dataset, the objectives of this study were to: investigate the use of predictive modeling techniques in forecasting future claims costs based on historical data; identify distinctive patterns of high-cost occupational injuries; and examine how well machine learning methods work in finding the predictive relationship between factors influencing occupational injuries and workers’ compensation claims occurrence and severity. The results lead to a better understanding of injury patterns, identification of prevalent causes of occupational injuries, and identification of high-risk industries and occupations. Therefore, various stakeholders such as policymakers, insurance companies, safety standard writers, and manufacturers of safety equipment can use the findings of the study to plan for remedial actions and revise safety standards. The implementation of safety measures by agribusiness organizations can prevent occupational injuries, save lives, and reduce the occurrence and cost of such incidents in agricultural work environments