595 research outputs found
30th European Congress on Obesity (ECO 2023)
This is the abstract book of 30th European Congress on Obesity (ECO 2023
Guiding âThe Intelligent English Travellerâ: The Collaborative and Interactive Victorian Serialized Handbook
Relying on a range of nineteenth-century genres and authorial voices, âGuiding the âIntelligent English Travellerââ spotlights John Murrayâs Handbooks for Travellers as collaborative, interactive, and multidisciplinary texts. Guidebooks from the Victorian age emerged from epistolary and travelogue genres, cited Romantic poets, depended on contributions from the great minds of the day, and informed contemporary fictional representations of travel. The Handbooks for Travellers were the exemplar of the serial guide. Their multimedia and -modal form, diverse author- and editorship, and commercial brand make them a possibly unique example of material history and publishing practice, as illustrated in my opening chapter, which relies on evidence gathered at the John Murray Archive in the National Library of Scotland. Subsequent chapters tracing âMurraysâ in the travel writing and fiction of George Eliot and Henry James underscore the Handbooksâ rhetorical influence and cultural reach. The coda to this project is more experimental, describing the development of an interactive digital map representing Murrayâs Handbook series for Europe. This map illustrates the temporal and geographic changes in the Murray series using the first three Handbooks as examples. My application of computational methods for interpreting the Handbooks emphasizes that these texts were tools that anticipate the iterative, interdisciplinary, intertextual, and multivocal processes at the heart of digital humanities work.Doctor of Philosoph
Accessibility of Health Data Representations for Older Adults: Challenges and Opportunities for Design
Health data of consumer off-the-shelf wearable devices is often conveyed to users through visual data representations and analyses. However, this is not always accessible to people with disabilities or older people due to low vision, cognitive impairments or literacy issues. Due to trade-offs between aesthetics predominance or information overload, real-time user feedback may not be conveyed easily from sensor devices through visual cues like graphs and texts. These difficulties may hinder critical data understanding. Additional auditory and tactile feedback can also provide immediate and accessible cues from these wearable devices, but it is necessary to understand existing data representation limitations initially. To avoid higher cognitive and visual overload, auditory and haptic cues can be designed to complement, replace or reinforce visual cues. In this paper, we outline the challenges in existing data representation and the necessary evidence to enhance the accessibility of health information from personal sensing devices used to monitor health parameters such as blood pressure, sleep, activity, heart rate and more. By creating innovative and inclusive user feedback, users will likely want to engage and interact with new devices and their own data
Applications
Volume 3 describes how resource-aware machine learning methods and techniques are used to successfully solve real-world problems. The book provides numerous specific application examples: in health and medicine for risk modelling, diagnosis, and treatment selection for diseases in electronics, steel production and milling for quality control during manufacturing processes in traffic, logistics for smart cities and for mobile communications
The Pathophysiology of Preeclampsia and Eclampsia
Preeclampsia is a hypertensive disorder of pregnancy, diagnosed after the 20th week of gestation in women experiencing new-onset hypertension along with symptoms affecting the liver, kidneys, or brain. In some cases, women with preeclampsia develop novel seizures or unexplained coma, at which time they are diagnosed with eclampsia. The mechanisms contributing to preeclampsia and eclampsia are not fully elucidated, although the placenta seems to play a critical role. Previous studies suggest that improper placentation stimulates mitochondrial dysfunction and the exaggerated release of placental-derived molecules including inflammatory cytokines, anti-angiogenic factors, reactive oxygen species, and cell-free nucleic acids into the maternal circulation that cause systemic vascular dysfunction. These, along with maternally derived molecules, act in concert, leading to hypertension and target organ damage during pregnancies complicated by preeclampsia and eclampsia.In this reprint, we present the original research articles and review papers published as part of the Special Issue: "The Pathophysiology of Preeclampsia and Eclampsia" in Cells
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