36,272 research outputs found
Some results on more flexible versions of Graph Motif
The problems studied in this paper originate from Graph Motif, a problem
introduced in 2006 in the context of biological networks. Informally speaking,
it consists in deciding if a multiset of colors occurs in a connected subgraph
of a vertex-colored graph. Due to the high rate of noise in the biological
data, more flexible definitions of the problem have been outlined. We present
in this paper two inapproximability results for two different optimization
variants of Graph Motif: one where the size of the solution is maximized, the
other when the number of substitutions of colors to obtain the motif from the
solution is minimized. We also study a decision version of Graph Motif where
the connectivity constraint is replaced by the well known notion of graph
modularity. While the problem remains NP-complete, it allows algorithms in FPT
for biologically relevant parameterizations
Recent Advances in Graph Partitioning
We survey recent trends in practical algorithms for balanced graph
partitioning together with applications and future research directions
Maximum common subgraph isomorphism algorithms for the matching of chemical structures
The maximum common subgraph (MCS) problem has become increasingly important in those aspects of chemoinformatics that involve the matching of 2D or 3D chemical structures. This paper provides a classification and a review of the many MCS algorithms, both exact and approximate, that have been described in the literature, and makes recommendations regarding their applicability to typical chemoinformatics tasks
On the Implementation of the Probabilistic Logic Programming Language ProbLog
The past few years have seen a surge of interest in the field of
probabilistic logic learning and statistical relational learning. In this
endeavor, many probabilistic logics have been developed. ProbLog is a recent
probabilistic extension of Prolog motivated by the mining of large biological
networks. In ProbLog, facts can be labeled with probabilities. These facts are
treated as mutually independent random variables that indicate whether these
facts belong to a randomly sampled program. Different kinds of queries can be
posed to ProbLog programs. We introduce algorithms that allow the efficient
execution of these queries, discuss their implementation on top of the
YAP-Prolog system, and evaluate their performance in the context of large
networks of biological entities.Comment: 28 pages; To appear in Theory and Practice of Logic Programming
(TPLP
A Novel Approach to Finding Near-Cliques: The Triangle-Densest Subgraph Problem
Many graph mining applications rely on detecting subgraphs which are
near-cliques. There exists a dichotomy between the results in the existing work
related to this problem: on the one hand the densest subgraph problem (DSP)
which maximizes the average degree over all subgraphs is solvable in polynomial
time but for many networks fails to find subgraphs which are near-cliques. On
the other hand, formulations that are geared towards finding near-cliques are
NP-hard and frequently inapproximable due to connections with the Maximum
Clique problem.
In this work, we propose a formulation which combines the best of both
worlds: it is solvable in polynomial time and finds near-cliques when the DSP
fails. Surprisingly, our formulation is a simple variation of the DSP.
Specifically, we define the triangle densest subgraph problem (TDSP): given
, find a subset of vertices such that , where is the number of triangles induced
by the set . We provide various exact and approximation algorithms which the
solve the TDSP efficiently. Furthermore, we show how our algorithms adapt to
the more general problem of maximizing the -clique average density. Finally,
we provide empirical evidence that the TDSP should be used whenever the output
of the DSP fails to output a near-clique.Comment: 42 page
Algorithmic and Statistical Perspectives on Large-Scale Data Analysis
In recent years, ideas from statistics and scientific computing have begun to
interact in increasingly sophisticated and fruitful ways with ideas from
computer science and the theory of algorithms to aid in the development of
improved worst-case algorithms that are useful for large-scale scientific and
Internet data analysis problems. In this chapter, I will describe two recent
examples---one having to do with selecting good columns or features from a (DNA
Single Nucleotide Polymorphism) data matrix, and the other having to do with
selecting good clusters or communities from a data graph (representing a social
or information network)---that drew on ideas from both areas and that may serve
as a model for exploiting complementary algorithmic and statistical
perspectives in order to solve applied large-scale data analysis problems.Comment: 33 pages. To appear in Uwe Naumann and Olaf Schenk, editors,
"Combinatorial Scientific Computing," Chapman and Hall/CRC Press, 201
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