Spectrally and Energy Efficient Wireless Communications: Signal and System Design, Mathematical Modelling and Optimisation

This thesis explores engineering studies and designs aiming to meeting the requirements of enhancing capacity and energy efficiency for next generation communication networks. Challenges of spectrum scarcity and energy constraints are addressed and new technologies are proposed, analytically investigated and examined. The thesis commences by reviewing studies on spectrally and energy-efficient techniques, with a special focus on non-orthogonal multicarrier modulation, particularly spectrally efficient frequency division multiplexing (SEFDM). Rigorous theoretical and mathematical modelling studies of SEFDM are presented. Moreover, to address the potential application of SEFDM under the 5th generation new radio (5G NR) heterogeneous numerologies, simulation-based studies of SEFDM coexisting with orthogonal frequency division multiplexing (OFDM) are conducted. New signal formats and corresponding transceiver structure are designed, using a Hilbert transform filter pair for shaping pulses. Detailed modelling and numerical investigations show that the proposed signal doubles spectral efficiency without performance degradation, with studies of two signal formats; uncoded narrow-band internet of things (NB-IoT) signals and unframed turbo coded multi-carrier signals. The thesis also considers using constellation shaping techniques and SEFDM for capacity enhancement in 5G system. Probabilistic shaping for SEFDM is proposed and modelled to show both transmission energy reduction and bandwidth saving with advantageous flexibility for data rate adaptation. Expanding on constellation shaping to improve performance further, a comparative study of multidimensional modulation techniques is carried out. A four-dimensional signal, with better noise immunity is investigated, for which metaheuristic optimisation algorithms are studied, developed, and conducted to optimise bit-to-symbol mapping. Finally, a specially designed machine learning technique for signal and system design in physical layer communications is proposed, utilising the application of autoencoder-based end-to-end learning. Multidimensional signal modulation with multidimensional constellation shaping is proposed and optimised by using machine learning techniques, demonstrating significant improvement in spectral and energy efficiencies

Spatially optimised sustainable urban development

PhD ThesisTackling urbanisation and climate change requires more sustainable and resilient cities, which in turn will require planners to develop a portfolio of measures to manage climate risks such as flooding, meet energy and greenhouse gas reduction targets, and prioritise development on brownfield sites to preserve greenspace. However, the policies, strategies and measures put in place to meet such objectives can frequently conflict with each other or deliver unintended consequences, hampering long-term sustainability. For example, the densification of cities in order to reduce transport energy use can increase urban heat island effects and surface water flooding from extreme rainfall events. In order to make coherent decisions in the presence of such complex multi-dimensional spatial conflicts, urban planners require sophisticated planning tools to identify and manage potential trade-offs between the spatial strategies necessary to deliver sustainability. To achieve this aim, this research has developed a multi-objective spatial optimisation framework for the spatial planning of new residential development within cities. The implemented framework develops spatial strategies of required new residential development that minimize conflicts between multiple sustainability objectives as a result of planning policy and climate change related hazards. Five key sustainability objectives have been investigated, namely; (i) minimizing risk from heat waves, (ii) minimizing the risk from flood events, (iii) minimizing travel costs in order to reduce transport emissions, (iv) minimizing urban sprawl and (v) preventing development on existing greenspace. A review identified two optimisation algorithms as suitable for this task. Simulated Annealing (SA) is a traditional optimisation algorithm that uses a probabilistic approach to seek out a global optima by iteratively assessing a wide range of spatial configurations against the objectives under consideration. Gradual ‘cooling’, or reducing the probability of jumping to a different region of the objective space, helps the SA to converge on globally optimal spatial patterns. Genetic Algorithms (GA) evolve successive generations of solutions, by both recombining attributes and randomly mutating previous generations of solutions, to search for and converge towards superior spatial strategies. The framework works towards, and outputs, a series of Pareto-optimal spatial plans that outperform all other plans in at least one objective. This approach allows for a range of best trade-off plans for planners to choose from. ii Both SA and GA were evaluated for an initial case study in Middlesbrough, in the North East of England, and were able to identify strategies which significantly improve upon the local authority’s development plan. For example, the GA approach is able to identify a spatial strategy that reduces the travel to work distance between new development and the central business district by 77.5% whilst nullifying the flood risk to the new development. A comparison of the two optimisation approaches for the Middlesbrough case study revealed that the GA is the more effective approach. The GA is more able to escape local optima and on average outperforms the SA by 56% in in the Pareto fronts discovered whilst discovering double the number of multi-objective Pareto-optimal spatial plans. On the basis of the initial Middlesbrough case study the GA approach was applied to the significantly larger, and more computationally complex, problem of optimising spatial development plans for London in the UK – a total area of 1,572km2. The framework identified optimal strategies in less than 400 generations. The analysis showed, for example, strategies that provide the lowest heat risk (compared to the feasible spatial plans found) can be achieved whilst also using 85% brownfield land to locate new development. The framework was further extended to investigate the impact of different development and density regulations. This enabled the identification of optimised strategies, albeit at lower building density, that completely prevent any increase in urban sprawl whilst also improving the heat risk objective by 60% against a business as usual development strategy. Conversely by restricting development to brownfield the ability of the spatial plan to optimise future heat risk is reduced by 55.6% against the business as usual development strategy. The results of both case studies demonstrate the potential of spatial optimisation to provide planners with optimal spatial plans in the presence of conflicting sustainability objectives. The resulting diagnostic information provides an analytical appreciation of the sensitivity between conflicts and therefore the overall robustness of a plan to uncertainty. With the inclusion of further objectives, and qualitative information unsuitable for this type of analysis, spatial optimization can constitute a powerful decision support tool to help planners to identify spatial development strategies that satisfy multiple sustainability objectives and provide an evidence base for better decision making

Computer-Assisted Electroanatomical Guidance for Cardiac Electrophysiology Procedures

Cardiac arrhythmias are serious life-threatening episodes affecting both the aging population and younger patients with pre-existing heart conditions. One of the most effective therapeutic procedures is the minimally-invasive catheter-driven endovascular electrophysiology study, whereby electrical potentials and activation patterns in the affected cardiac chambers are measured and subsequent ablation of arrhythmogenic tissue is performed. Despite emerging technologies such as electroanatomical mapping and remote intraoperative navigation systems for improved catheter manipulation and stability, successful ablation of arrhythmias is still highly-dependent on the operator’s skills and experience. This thesis proposes a framework towards standardisation in the electroanatomical mapping and ablation planning by merging knowledge transfer from previous cases and patient-specific data. In particular, contributions towards four different procedural aspects were made: optimal electroanatomical mapping, arrhythmia path computation, catheter tip stability analysis, and ablation simulation and optimisation. In order to improve the intraoperative electroanatomical map, anatomical areas of high mapping interest were proposed, as learned from previous electrophysiology studies. Subsequently, the arrhythmic wave propagation on the endocardial surface and potential ablation points were computed. The ablation planning is further enhanced, firstly by the analysis of the catheter tip stability and the probability of slippage at sparse locations on the endocardium and, secondly, by the simulation of the ablation result from the computation of convolutional matrices which model mathematically the ablation process. The methods proposed by this thesis were validated on data from patients with complex congenital heart disease, who present unusual cardiac anatomy and consequently atypical arrhythmias. The proposed methods also build a generic framework for computer guidance of electrophysiology, with results showing complementary information that can be easily integrated into the clinical workflow.Open Acces

Physics Performance Report for PANDA Strong Interaction Studies with Antiprotons

To study fundamental questions of hadron and nuclear physics in interactions of antiprotons with nucleons and nuclei, the universal PANDA detector will be build. Gluonic excitations, the physics of strange and charm quarks and nucleon structure studies will be performed with unprecedented accuracy thereby allowing high-precision tests of the strong interaction. The proposed PANDA detector is a state-of-the-art internal target detector at the HESR at FAIR allowing the detection and identifcation of neutral and charged particles generated within the relevant angular and energy range. This report presents a summary of the physics accessible at PANDA and what performance can be expected

Structure-based molecular design: identification of modulators of the NCS1:D2 interaction

The interactions between specific proteins (PPIs) is known to be critical for numerous biological processes, implicating them in many pathological conditions, thus modulation of PPIs has substantial therapeutic potential. The complexity, topography and, in some cases, the hydrophobic nature of the PPIs presents a considerable challenge. One important PPI of therapeutic interest, that has been implicated in the treatment of bi-polar and schizophrenia disorders, occurs between neuronal calcium sensor 1 (NCS1) and the dopamine receptor 2 (D2). The research detailed in this thesis describes the application of structure-based drug design (SBDD) to select small molecule compounds for synthesis and biophysical assessment against the NCS1 D2 target. The use of a structure-based drug design method, has been seen in previous PPI studies and uses a combination of techniques, including computational modelling used in conjunction with “hit identification” and ”hit to lead” optimisation processes in a drug discovery pipeline. The biophysical analyses of the first generation synthesised were hampered by problems associated with limited aqueous solubility, restricting the determination of accurate affinity values. Thus a second generation of ligands were developed with addition of solubilising groups to the scaffold, based on that of the compound 1-benzyl-N-((2-methoxy-4,6-dimethylpyridin-3-yl)methyl)-3,5-dimethyl-1H-pyrazole-4-carboxamide (Inhibitor 2). The second generation of compounds displayed improved aqueous solubility, in particular; 1-(4-chlorobenzyl)-3,5-dimethyl-N-((5-(morpholine-4-carbonyl)pyridin-3-yl)methyl)-1H-pyrazole-4-carboxamide (Inhibitor 5), presented the most promising hit. A fragment based approach was also investigated, adapting the SBDD approach by developing a computational pipeline to select 28 compounds from a library of 1137 for biophysical screening. A two-step biophysical screening protocol was developed; employing high throughput NMR techniques, five fragments were identified alongside a hit fragment candidate 5-methyl-3-phenyl-1H-pyrazole (4.21). This research presents two applications of an in silico screening protocol able to identify ligands targeting PPIs. Through verification via biophysical techniques, a number of compounds were determined as hits however, no affinity for the target was determined. This project highlights that despite some successes, many challenges remain in the development of targeting PPIs with small molecules

Physics Performance Report for PANDA: Strong Interaction Studies with Antiprotons

To study fundamental questions of hadron and nuclear physics in interactions of antiprotons with nucleons and nuclei, the universal PANDA detector will be built. Gluonic excitations, the physics of strange and charm quarks and nucleon structure studies will be performed with unprecedented accuracy thereby allowing high-precision tests of the strong interaction. The proposed PANDA detector is a state-of-the art internal target detector at the HESR at FAIR allowing the detection and identification of neutral and charged particles generated within the relevant angular and energy range. This report presents a summary of the physics accessible at PANDA and what performance can be expected.Comment: 216 page

Physics Performance Report for PANDA : Strong Interaction Studies with Antiprotons

To study fundamental questions of hadron and nuclear physics in interactions of antiprotons with nucleons and nuclei, the universal PANDA detector will be built. Gluonic excitations, the physics of strange and charm quarks and nucleon structure studies will be performed with unprecedented accuracy thereby allowing high-precision tests of the strong interaction. The proposed PANDA detector is a state-of-the art internal target detector at the HESR at FAIR allowing the detection and identification of neutral and charged particles generated within the relevant angular and energy range. This report presents a summary of the physics accessible at PANDA and what performance can be expected. Comment: 216 page

Fuelling the zero-emissions road freight of the future: routing of mobile fuellers

The future of zero-emissions road freight is closely tied to the sufficient availability of new and clean fuel options such as electricity and Hydrogen. In goods distribution using Electric Commercial Vehicles (ECVs) and Hydrogen Fuel Cell Vehicles (HFCVs) a major challenge in the transition period would pertain to their limited autonomy and scarce and unevenly distributed refuelling stations. One viable solution to facilitate and speed up the adoption of ECVs/HFCVs by logistics, however, is to get the fuel to the point where it is needed (instead of diverting the route of delivery vehicles to refuelling stations) using "Mobile Fuellers (MFs)". These are mobile battery swapping/recharging vans or mobile Hydrogen fuellers that can travel to a running ECV/HFCV to provide the fuel they require to complete their delivery routes at a rendezvous time and space. In this presentation, new vehicle routing models will be presented for a third party company that provides MF services. In the proposed problem variant, the MF provider company receives routing plans of multiple customer companies and has to design routes for a fleet of capacitated MFs that have to synchronise their routes with the running vehicles to deliver the required amount of fuel on-the-fly. This presentation will discuss and compare several mathematical models based on different business models and collaborative logistics scenarios

Políticas de Copyright de Publicações Científicas em Repositórios Institucionais: O Caso do INESC TEC

A progressiva transformação das práticas científicas, impulsionada pelo desenvolvimento das novas Tecnologias de Informação e Comunicação (TIC), têm possibilitado aumentar o acesso à informação, caminhando gradualmente para uma abertura do ciclo de pesquisa. Isto permitirá resolver a longo prazo uma adversidade que se tem colocado aos investigadores, que passa pela existência de barreiras que limitam as condições de acesso, sejam estas geográficas ou financeiras. Apesar da produção científica ser dominada, maioritariamente, por grandes editoras comerciais, estando sujeita às regras por estas impostas, o Movimento do Acesso Aberto cuja primeira declaração pública, a Declaração de Budapeste (BOAI), é de 2002, vem propor alterações significativas que beneficiam os autores e os leitores. Este Movimento vem a ganhar importância em Portugal desde 2003, com a constituição do primeiro repositório institucional a nível nacional. Os repositórios institucionais surgiram como uma ferramenta de divulgação da produção científica de uma instituição, com o intuito de permitir abrir aos resultados da investigação, quer antes da publicação e do próprio processo de arbitragem (preprint), quer depois (postprint), e, consequentemente, aumentar a visibilidade do trabalho desenvolvido por um investigador e a respetiva instituição. O estudo apresentado, que passou por uma análise das políticas de copyright das publicações científicas mais relevantes do INESC TEC, permitiu não só perceber que as editoras adotam cada vez mais políticas que possibilitam o auto-arquivo das publicações em repositórios institucionais, como também que existe todo um trabalho de sensibilização a percorrer, não só para os investigadores, como para a instituição e toda a sociedade. A produção de um conjunto de recomendações, que passam pela implementação de uma política institucional que incentive o auto-arquivo das publicações desenvolvidas no âmbito institucional no repositório, serve como mote para uma maior valorização da produção científica do INESC TEC.The progressive transformation of scientific practices, driven by the development of new Information and Communication Technologies (ICT), which made it possible to increase access to information, gradually moving towards an opening of the research cycle. This opening makes it possible to resolve, in the long term, the adversity that has been placed on researchers, which involves the existence of barriers that limit access conditions, whether geographical or financial. Although large commercial publishers predominantly dominate scientific production and subject it to the rules imposed by them, the Open Access movement whose first public declaration, the Budapest Declaration (BOAI), was in 2002, proposes significant changes that benefit the authors and the readers. This Movement has gained importance in Portugal since 2003, with the constitution of the first institutional repository at the national level. Institutional repositories have emerged as a tool for disseminating the scientific production of an institution to open the results of the research, both before publication and the preprint process and postprint, increase the visibility of work done by an investigator and his or her institution. The present study, which underwent an analysis of the copyright policies of INESC TEC most relevant scientific publications, allowed not only to realize that publishers are increasingly adopting policies that make it possible to self-archive publications in institutional repositories, all the work of raising awareness, not only for researchers but also for the institution and the whole society. The production of a set of recommendations, which go through the implementation of an institutional policy that encourages the self-archiving of the publications developed in the institutional scope in the repository, serves as a motto for a greater appreciation of the scientific production of INESC TEC

Unmet goals of tracking: within-track heterogeneity of students' expectations for

Educational systems are often characterized by some form(s) of ability grouping, like tracking. Although substantial variation in the implementation of these practices exists, it is always the aim to improve teaching efficiency by creating homogeneous groups of students in terms of capabilities and performances as well as expected pathways. If students’ expected pathways (university, graduate school, or working) are in line with the goals of tracking, one might presume that these expectations are rather homogeneous within tracks and heterogeneous between tracks. In Flanders (the northern region of Belgium), the educational system consists of four tracks. Many students start out in the most prestigious, academic track. If they fail to gain the necessary credentials, they move to the less esteemed technical and vocational tracks. Therefore, the educational system has been called a 'cascade system'. We presume that this cascade system creates homogeneous expectations in the academic track, though heterogeneous expectations in the technical and vocational tracks. We use data from the International Study of City Youth (ISCY), gathered during the 2013-2014 school year from 2354 pupils of the tenth grade across 30 secondary schools in the city of Ghent, Flanders. Preliminary results suggest that the technical and vocational tracks show more heterogeneity in student’s expectations than the academic track. If tracking does not fulfill the desired goals in some tracks, tracking practices should be questioned as tracking occurs along social and ethnic lines, causing social inequality