16,149 research outputs found
Experiences of Engineering Grid-Based Medical Software
Objectives: Grid-based technologies are emerging as potential solutions for
managing and collaborating distributed resources in the biomedical domain. Few
examples exist, however, of successful implementations of Grid-enabled medical
systems and even fewer have been deployed for evaluation in practice. The
objective of this paper is to evaluate the use in clinical practice of a
Grid-based imaging prototype and to establish directions for engineering future
medical Grid developments and their subsequent deployment. Method: The
MammoGrid project has deployed a prototype system for clinicians using the Grid
as its information infrastructure. To assist in the specification of the system
requirements (and for the first time in healthgrid applications), use-case
modelling has been carried out in close collaboration with clinicians and
radiologists who had no prior experience of this modelling technique. A
critical qualitative and, where possible, quantitative analysis of the
MammoGrid prototype is presented leading to a set of recommendations from the
delivery of the first deployed Grid-based medical imaging application. Results:
We report critically on the application of software engineering techniques in
the specification and implementation of the MammoGrid project and show that
use-case modelling is a suitable vehicle for representing medical requirements
and for communicating effectively with the clinical community. This paper also
discusses the practical advantages and limitations of applying the Grid to
real-life clinical applications and presents the consequent lessons learned.Comment: 18 pages, 2 tables, 5 figures. In press International Journal of
Medical Informatics. Elsevier publisher
Improving knowledge management through the support of image examination and data annotation using DICOM structured reporting
[EN] An important effort has been invested on improving the image diagnosis process in different medical areas using information technologies. The field of medical imaging involves two main data types: medical imaging and reports. Developments based on the DICOM standard have demonstrated to be a convenient and widespread solution among the medical community. The main objective of this work is to design a Web application prototype that will be able to improve diagnosis and follow-on of breast cancer patients. It is based on TRENCADIS middleware, which provides a knowledge-oriented storage model composed by federated repositories of DICOM image studies and DICOM-SR medical reports. The full structure and contents of the diagnosis reports are used as metadata for indexing images. The TRENCADIS infrastructure takes full advantage of Grid technologies by deploying multi-resource grid services that enable multiple views (reports schemes) of the knowledge database. The paper presents a real deployment of such Web application prototype in the Dr. Peset Hospital providing radiologists with a tool to create, store and search diagnostic reports based on breast cancer explorations (mammography, magnetic resonance, ultrasound, pre-surgery biopsy and post-surgery biopsy), improving support for diagnostics decisions. A technical details for use cases (outlining enhanced multi-resource grid services communication and processing steps) and interactions between actors and the deployed prototype are described. As a result, information is more structured, the logic is clearer, network messages have been reduced and, in general, the system is more resistant to failures.The authors wish to thank the financial support received from The Spanish Ministry of Education and Science to develop the project "CodeCloud", with reference TIN2010-17804.Salavert Torres, J.; Segrelles Quilis, JD.; Blanquer Espert, I.; Hernández García, V. (2012). Improving knowledge management through the support of image examination and data annotation using DICOM structured reporting. Journal of Biomedical Informatics. 45(6):1066-1074. https://doi.org/10.1016/j.jbi.2012.07.004S1066107445
A perspective on the Healthgrid initiative
This paper presents a perspective on the Healthgrid initiative which involves
European projects deploying pioneering applications of grid technology in the
health sector. In the last couple of years, several grid projects have been
funded on health related issues at national and European levels. A crucial
issue is to maximize their cross fertilization in the context of an environment
where data of medical interest can be stored and made easily available to the
different actors in healthcare, physicians, healthcare centres and
administrations, and of course the citizens. The Healthgrid initiative,
represented by the Healthgrid association (http://www.healthgrid.org), was
initiated to bring the necessary long term continuity, to reinforce and promote
awareness of the possibilities and advantages linked to the deployment of GRID
technologies in health. Technologies to address the specific requirements for
medical applications are under development. Results from the DataGrid and other
projects are given as examples of early applications.Comment: 6 pages, 1 figure. Accepted by the Second International Workshop on
Biomedical Computations on the Grid, at the 4th IEEE/ACM International
Symposium on Cluster Computing and the Grid (CCGrid 2004). Chicago USA, April
200
End-to-End QoS Support for a Medical Grid Service Infrastructure
Quality of Service support is an important prerequisite for the adoption of Grid technologies for medical applications. The GEMSS Grid infrastructure addressed this issue by offering end-to-end QoS in the form of explicit timeliness guarantees for compute-intensive medical simulation services. Within GEMSS, parallel applications installed on clusters or other HPC hardware may be exposed as QoS-aware Grid services for which clients may dynamically negotiate QoS constraints with respect to response time and price using Service Level Agreements. The GEMSS infrastructure and middleware is based on standard Web services technology and relies on a reservation based approach to QoS coupled with application specific performance models. In this paper we present an overview of the GEMSS infrastructure, describe the available QoS and security mechanisms, and demonstrate the effectiveness of our methods with a Grid-enabled medical imaging service
Grid Databases for Shared Image Analysis in the MammoGrid Project
The MammoGrid project aims to prove that Grid infrastructures can be used for
collaborative clinical analysis of database-resident but geographically
distributed medical images. This requires: a) the provision of a
clinician-facing front-end workstation and b) the ability to service real-world
clinician queries across a distributed and federated database. The MammoGrid
project will prove the viability of the Grid by harnessing its power to enable
radiologists from geographically dispersed hospitals to share standardized
mammograms, to compare diagnoses (with and without computer aided detection of
tumours) and to perform sophisticated epidemiological studies across national
boundaries. This paper outlines the approach taken in MammoGrid to seamlessly
connect radiologist workstations across a Grid using an "information
infrastructure" and a DICOM-compliant object model residing in multiple
distributed data stores in Italy and the UKComment: 10 pages, 5 figure
Cloud Storage and Bioinformatics in a private cloud deployment: Lessons for Data Intensive research
This paper describes service portability for a private cloud deployment, including a detailed case study about Cloud Storage and bioinformatics services developed as part of the Cloud Computing Adoption Framework (CCAF). Our Cloud Storage design and deployment is based on Storage Area Network (SAN) technologies, details of which include functionalities, technical implementation, architecture and user support. Experiments for data services (backup automation, data recovery and data migration) are performed and results confirm backup automation is completed swiftly and is reliable for data-intensive research. The data recovery result confirms that execution time is in proportion to quantity of recovered data, but the failure rate increases in an exponential manner. The data migration result confirms execution time is in proportion to disk volume of migrated data, but again the failure rate increases in an exponential manner. In addition, benefits of CCAF are illustrated using several bioinformatics examples such as tumour modelling, brain imaging, insulin molecules and simulations for medical training. Our Cloud Storage solution described here offers cost reduction, time-saving and user friendliness
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