EEG sleep stages identification based on weighted undirected complex networks

Sleep scoring is important in sleep research because any errors in the scoring of the patient's sleep electroencephalography (EEG) recordings can cause serious problems such as incorrect diagnosis, medication errors, and misinterpretations of patient's EEG recordings. The aim of this research is to develop a new automatic method for EEG sleep stages classification based on a statistical model and weighted brain networks. Methods each EEG segment is partitioned into a number of blocks using a sliding window technique. A set of statistical features are extracted from each block. As a result, a vector of features is obtained to represent each EEG segment. Then, the vector of features is mapped into a weighted undirected network. Different structural and spectral attributes of the networks are extracted and forwarded to a least square support vector machine (LS-SVM) classifier. At the same time the network's attributes are also thoroughly investigated. It is found that the network's characteristics vary with their sleep stages. Each sleep stage is best represented using the key features of their networks. Results In this paper, the proposed method is evaluated using two datasets acquired from different channels of EEG (Pz-Oz and C3-A2) according to the R&K and the AASM without pre-processing the original EEG data. The obtained results by the LS-SVM are compared with those by Naïve, k-nearest and a multi-class-SVM. The proposed method is also compared with other benchmark sleep stages classification methods. The comparison results demonstrate that the proposed method has an advantage in scoring sleep stages based on single channel EEG signals. Conclusions An average accuracy of 96.74% is obtained with the C3-A2 channel according to the AASM standard, and 96% with the Pz-Oz channel based on the R&K standard

Deep residual networks for automatic sleep stage classification of raw polysomnographic waveforms

We have developed an automatic sleep stage classification algorithm based on deep residual neural networks and raw polysomnogram signals. Briefly, the raw data is passed through 50 convolutional layers before subsequent classification into one of five sleep stages. Three model configurations were trained on 1850 polysomnogram recordings and subsequently tested on 230 independent recordings. Our best performing model yielded an accuracy of 84.1% and a Cohen's kappa of 0.746, improving on previous reported results by other groups also using only raw polysomnogram data. Most errors were made on non-REM stage 1 and 3 decisions, errors likely resulting from the definition of these stages. Further testing on independent cohorts is needed to verify performance for clinical use

Deep Convolutional Neural Networks for Interpretable Analysis of EEG Sleep Stage Scoring

Sleep studies are important for diagnosing sleep disorders such as insomnia, narcolepsy or sleep apnea. They rely on manual scoring of sleep stages from raw polisomnography signals, which is a tedious visual task requiring the workload of highly trained professionals. Consequently, research efforts to purse for an automatic stage scoring based on machine learning techniques have been carried out over the last years. In this work, we resort to multitaper spectral analysis to create visually interpretable images of sleep patterns from EEG signals as inputs to a deep convolutional network trained to solve visual recognition tasks. As a working example of transfer learning, a system able to accurately classify sleep stages in new unseen patients is presented. Evaluations in a widely-used publicly available dataset favourably compare to state-of-the-art results, while providing a framework for visual interpretation of outcomes.Comment: 8 pages, 1 figure, 2 tables, IEEE 2017 International Workshop on Machine Learning for Signal Processin

RED: Deep Recurrent Neural Networks for Sleep EEG Event Detection

The brain electrical activity presents several short events during sleep that can be observed as distinctive micro-structures in the electroencephalogram (EEG), such as sleep spindles and K-complexes. These events have been associated with biological processes and neurological disorders, making them a research topic in sleep medicine. However, manual detection limits their study because it is time-consuming and affected by significant inter-expert variability, motivating automatic approaches. We propose a deep learning approach based on convolutional and recurrent neural networks for sleep EEG event detection called Recurrent Event Detector (RED). RED uses one of two input representations: a) the time-domain EEG signal, or b) a complex spectrogram of the signal obtained with the Continuous Wavelet Transform (CWT). Unlike previous approaches, a fixed time window is avoided and temporal context is integrated to better emulate the visual criteria of experts. When evaluated on the MASS dataset, our detectors outperform the state of the art in both sleep spindle and K-complex detection with a mean F1-score of at least 80.9% and 82.6%, respectively. Although the CWT-domain model obtained a similar performance than its time-domain counterpart, the former allows in principle a more interpretable input representation due to the use of a spectrogram. The proposed approach is event-agnostic and can be used directly to detect other types of sleep events.Comment: 8 pages, 5 figures. In proceedings of the 2020 International Joint Conference on Neural Networks (IJCNN 2020

Investigation of Machine Learning Approaches for Traumatic Brain Injury Classification via EEG Assessment in Mice.

Due to the difficulties and complications in the quantitative assessment of traumatic brain injury (TBI) and its increasing relevance in today's world, robust detection of TBI has become more significant than ever. In this work, we investigate several machine learning approaches to assess their performance in classifying electroencephalogram (EEG) data of TBI in a mouse model. Algorithms such as decision trees (DT), random forest (RF), neural network (NN), support vector machine (SVM), K-nearest neighbors (KNN) and convolutional neural network (CNN) were analyzed based on their performance to classify mild TBI (mTBI) data from those of the control group in wake stages for different epoch lengths. Average power in different frequency sub-bands and alpha:theta power ratio in EEG were used as input features for machine learning approaches. Results in this mouse model were promising, suggesting similar approaches may be applicable to detect TBI in humans in practical scenarios