EEG sleep stages identification based on weighted undirected complex networks

Sleep scoring is important in sleep research because any errors in the scoring of the patient's sleep electroencephalography (EEG) recordings can cause serious problems such as incorrect diagnosis, medication errors, and misinterpretations of patient's EEG recordings. The aim of this research is to develop a new automatic method for EEG sleep stages classification based on a statistical model and weighted brain networks. Methods each EEG segment is partitioned into a number of blocks using a sliding window technique. A set of statistical features are extracted from each block. As a result, a vector of features is obtained to represent each EEG segment. Then, the vector of features is mapped into a weighted undirected network. Different structural and spectral attributes of the networks are extracted and forwarded to a least square support vector machine (LS-SVM) classifier. At the same time the network's attributes are also thoroughly investigated. It is found that the network's characteristics vary with their sleep stages. Each sleep stage is best represented using the key features of their networks. Results In this paper, the proposed method is evaluated using two datasets acquired from different channels of EEG (Pz-Oz and C3-A2) according to the R&K and the AASM without pre-processing the original EEG data. The obtained results by the LS-SVM are compared with those by Naïve, k-nearest and a multi-class-SVM. The proposed method is also compared with other benchmark sleep stages classification methods. The comparison results demonstrate that the proposed method has an advantage in scoring sleep stages based on single channel EEG signals. Conclusions An average accuracy of 96.74% is obtained with the C3-A2 channel according to the AASM standard, and 96% with the Pz-Oz channel based on the R&K standard

Sleep Stage Classification: A Deep Learning Approach

Sleep occupies significant part of human life. The diagnoses of sleep related disorders are of great importance. To record specific physical and electrical activities of the brain and body, a multi-parameter test, called polysomnography (PSG), is normally used. The visual process of sleep stage classification is time consuming, subjective and costly. To improve the accuracy and efficiency of the sleep stage classification, automatic classification algorithms were developed. In this research work, we focused on pre-processing (filtering boundaries and de-noising algorithms) and classification steps of automatic sleep stage classification. The main motivation for this work was to develop a pre-processing and classification framework to clean the input EEG signal without manipulating the original data thus enhancing the learning stage of deep learning classifiers. For pre-processing EEG signals, a lossless adaptive artefact removal method was proposed. Rather than other works that used artificial noise, we used real EEG data contaminated with EOG and EMG for evaluating the proposed method. The proposed adaptive algorithm led to a significant enhancement in the overall classification accuracy. In the classification area, we evaluated the performance of the most common sleep stage classifiers using a comprehensive set of features extracted from PSG signals. Considering the challenges and limitations of conventional methods, we proposed two deep learning-based methods for classification of sleep stages based on Stacked Sparse AutoEncoder (SSAE) and Convolutional Neural Network (CNN). The proposed methods performed more efficiently by eliminating the need for conventional feature selection and feature extraction steps respectively. Moreover, although our systems were trained with lower number of samples compared to the similar studies, they were able to achieve state of art accuracy and higher overall sensitivity

Developing new techniques to analyse and classify EEG signals

A massive amount of biomedical time series data such as Electroencephalograph (EEG), electrocardiography (ECG), Electromyography (EMG) signals are recorded daily to monitor human performance and diagnose different brain diseases. Effectively and accurately analysing these biomedical records is considered a challenge for researchers. Developing new techniques to analyse and classify these signals can help manage, inspect and diagnose these signals. In this thesis novel methods are proposed for EEG signals classification and analysis based on complex networks, a statistical model and spectral graph wavelet transform. Different complex networks attributes were employed and studied in this thesis to investigate the main relationship between behaviours of EEG signals and changes in networks attributes. Three types of EEG signals were investigated and analysed; sleep stages, epileptic and anaesthesia. The obtained results demonstrated the effectiveness of the proposed methods for analysing these three EEG signals types. The methods developed were applied to score sleep stages EEG signals, and to analyse epileptic, as well as anaesthesia EEG signals. The outcomes of the project will help support experts in the relevant medical fields and decrease the cost of diagnosing brain diseases

Estudio del método Common Spatial Patterns y sus variantes en interfaces cerebro-ordenador

Las comunicaciones Brain Computer Interface (BCI) consisten en una tecnología que permite que las personas puedan comunicarse con una máquina o un ordenador, usando para ello el cerebro y en la mayoría de los casos un casco de EEG. Este campo supone un gran reto para la ingeniería (junto con muchas otras ramas de conocimiento) y en la actualidad se está investigando mucho y se están realizando grandes avances. La importancia de investigar y avanzar en la realización de estos sistemas se debe a que los sistemas BCI pueden ser de gran ayuda a personas que sufren de algunos trastornos de parálisis cerebral, o que padecen de otras enfermedades o discapacidades que impidan el uso normal de sus habilidades motoras. Se cree que estos sistemas pueden mejorar considerablemente la calidad de vida de estas personas, para las cuales pequeños avances y cambios implican grandes mejoras. Common Spatials Patterns (CSP) es un algoritmo muy conocido y ampliamente usado que ha cobrado gran importancia durante los últimos años por sus aplicaciones en BCI para los sistemas basados en EEG multicanales. El algoritmo CSP consiste en encontrar un filtro espacial óptimo, que reduzca la dimensionalidad de las señales originales pudiendo tomar tantos canales como se desee. El objetivo de este trabajo consiste en realizar un repaso sobre esta técnica y también sobre Linear Discriminant Analysis (LDA), que se trata de una técnica de clasificación lineal. Además, se ha implementado un algoritmo basado en CSP con el que se consiguen mejorar los resultados que se obtienen usando únicamente la técnica de CSP. El algoritmo desarrollado es capaz de distinguir entre dos clases y además, se ha realizado una extensión en la que se distingue entre cuatro clases usando un sistema de votaciones simple. Para poder probar y comprobar el correcto funcionamiento de ambos algoritmos desarrollados, se han usado los datos procedentes de una competición pública de BCI, que ha sido usada como referencia en numerosos artículos. Esto nos ha permitido comparar los resultados obtenidos con nuestros algortimos con aquellos obtenidos mediante otras técnicas y variantes de CSP, como sería el caso del algoritmo RSTFC, que también ha sido implementado y probado durante este trabajo. Por último, se han obtenido unas conclusiones de los sistemas BCI, así como de las distintas técnicas mencionadas anteriormente. Para ello nos hemos ayudado de gráficas y medidas obtenidas a partir de los resultados obtenidos. También hemos podido extraer conclusiones a partir de ilustraciones de los filtros espaciales calculados con CSPThe BCI communication is a technology which allows to people to communicate with a machine or a computer using their own brains and normally a EEG helmet. This field of knowledge is a great challenge for engineering (and for other fields). Now days BCI communications are being very studied and developed, having great advances. The importance of developing better BCI system falls in the believing that it can help a lot of people who are suffering of some kind of paralysis or some kinds of motor inability. We believe that this technology can be very useful for those people and that their lifestyle could be increased significantly, to whom little improvement means a lot. CSP is very a well-known algorithm and it has been widely used in many BCI system especially in those systems which use EEG helmets. CSP is used to reduce the dimensionality of the EEG signals allowing to choose how many channels the user needs. The main of this work is to make a review in CSP algorithm and about LDA too, which is a classification technique. Furthermore, an algorithm based on these two techniques has been developed which improve the results obtained using the simple CSP. The algorithm developed is able to classify between two classes but an extension have been done making able to distingue between four imaginary movements. These extension is based in a simple vote system. Whit the purpose of comparing and checking the well behavior theses algorithms they have been test over a public set of data. This set of data is given from IV BCI competition. These data have been wildly used in multiple articles which has allow us to compare the algorithm whit others, like the RSTFC algorithm which have been also tried in this work. Finally, some conclusions about BCI system and the algorithm have been done. To accomplish that we used some plots about the results and about the filters that CSP provides.Universidad de Sevilla. Máster en Ingeniería de Telecomunicació

Diseño y desarrollo de un sistema para automatizar el diagnóstico de narcolepsia tipo II mediante redes neuronales artificiales usando el registro polisomnográfico en un instituto del sueño

La tesis titulada “Diseño y desarrollo de un sistema para automatizar el diagnóstico de narcolepsia tipo II mediante redes neuronales artificiales usando el registro polisomnográfico en un instituto del sueño”, tiene como objetivo principal diseñar y desarrollar un sistema para apoyar al diagnóstico de la narcolepsia tipo II mediante redes neuronales aplicado a las señales electroencefalográficas (EEG) con la finalidad de brindar un soporte tecnológico y automatizado para la evaluación de pacientes neurológicos. Las muestras utilizadas fueron provenientes de la Clínica San Felipe, del Área de Neurociencias, con un total de 10 pacientes controles y 7 pacientes con narcolepsia tipo II. Se utilizó el estándar de la Academia Americana de la Medicina del Sueño (AASM) para obtener épocas de treinta segundos en los canales F3A2, F4A1, C3A2, C4A1, O1A2 y O2A1. Se implementó algoritmos para analizar las señales EEG en dominios de frecuencia y tiempo – frecuencia a través de la Transformada de Fourier y la Transformada Wavelet respectivamente, para su posterior automatización con el perceptrón multicapa (MLP). Entre las conclusiones se encontró patrones característicos entre cada estadío del sueño (WAKE, REM, N3, N2, N1), se observó un menor ancho de banda en los husos del sueño y el doble de dinamismo en el ciclo del sueño en los pacientes con narcolepsia tipo II, el sistema presenta una exactitud, precisión y similitud mayor al 83%.TesisCampus Lima Centr

Análisis de electroencefalogramas para la detección automática de las fases del sueño

Las enfermedades del sueño son cada vez más comunes debido al estresante estilo de vida de la sociedad actual. Un paso fundamental en su estudio y diagnóstico es detectar correctamente las diferentes fases del sueño. Avances en áreas como el Deep learning han permitido desarrollar métodos que automatizan esta detección, presentando una alternativa a la clasificación mediante inspección visual realizada hasta la fecha. En este trabajo se ha indagado en el uso de redes neuronales convolucionales (CNN) como clasificadores de fases del sueño, usando para ello la señal de electroencefalograma (EEG). El comportamiento de esta señal difiere entre niños y adultos. Sin embargo, los estudios publicados hasta ahora se han centrado únicamente en pacientes adultos, lo que provoca que los modelos de clasificación no sean fácilmente generalizables. Conseguir un método de clasificación basado en CNN que permita una detección precisa de las fases del sueño en niños, y comprobar si se puede entrenar un modelo que alcance resultados óptimos al evaluar sujetos de diferentes edades, son los objetivos principales de este trabajo. Para ello, se han usado dos amplias bases de datos públicas procedentes de los estudios Sleep Heart Health Study (SHHS) y Childhood Adenotonsillectomy Trial (CHAT), que contienen 5793 registros de adultos y 453 registros de niños, respectivamente. El proceso de entrenamiento y optimización de la red CNN se ha probado modificando el número de capas y su parámetro de regularización, este último buscando asegurar que no haya sobreentrenamiento. Tras conseguir un modelo con alto rendimiento al clasificar la población adulta, se ha evaluado dicho modelo en los registros pediátricos. El mismo procedimiento se ha realizado de manera inversa, probando en la población adulta un modelo entrenado únicamente con niños. Además, se ha obtenido un modelo conjunto usando registros de ambas bases de datos en los grupos de entrenamiento/validación/test. Para homogeneizar las señales de las dos bases, se ha implementado re-muestreo a la misma frecuencia, re-referenciado a la media de los canales utilizados en cada caso, y estandarización para igualar los límites de amplitud. Los resultados muestran que los modelos entrenados con registros de una única base de datos clasifican con alta precisión siempre que se apliquen sobre sujetos en los mismos rangos de edad, consiguiéndose una precisión del 0.815 y un kappa de Cohen de 0.738 en el caso de sujetos adultos y precisión de 0.84 y kappa de 0.77 en el caso de niños, lo que es coherente con estudios previos. No obstante, al clasificar un grupo de edad diferente, estos valores disminuyen. Sin embargo, el modelo entrenado con registros de diferentes edades sí que consigue detectar de manera precisa registros de ambas bases, llegando a una precisión de 0.81 y a un kappa de 0.75 al evaluarlo en un grupo de test conjunto. Estos resultados sugieren la necesidad de incluir sujetos de diferentes edades en el entrenamiento para conseguir modelos más generalizables.Sleep disorders are very common nowadays due to the stressful lifestyle of the current society. A fundamental step in the study and diagnosis of these disorders is to successfully detect the different sleep stages. Recent investigation in fields like Deep learning has led to the development of methods that automatize this detection, becoming an alternative to the visual classification mostly used up to the date. This project explores the application of convolutional neural networks (CNN) as methods for sleep staging classification, using the brain signal of the electroencephalogram (EEG). The behavior of this signal changes between children and adults. However, studies published up to the date mostly focus on grown up patients, issue that causes a poor generalization of the classification models when applied to other age ranges. Finding a classification method based on CNN that shows an accurate detection of children´s sleep stages, and training a model that reaches high performance when evaluated with subjects of different ages, are the two main goals of this work. In order to achieve these goals, two large public data bases have been used, coming from the Sleep Heart Health Study (SHHS) and the Childhood Adenotonsillectomy Trial (CHAT), and containing 5793 adults´ recordings and 453 children´s recordings, respectively. The process of training and optimizing the neural network has been conducted by varying the number of convolutional layers and the dropout percentage, the latter being used to minimize the risk of model overfitting. Once an effective model for the classification of adults´ recordings is found, it gets tested with the pediatric recordings. The same procedure is followed the other way around, testing with the recordings of adults a model trained only using kids´ signals. Furthermore, a mixed model is obtained by including subjects from both data bases in the training/validation/test groups. With the aim of homogenize the signals of the two data bases, three different actions have been taken: re-sampling the recordings to the same frequency, applying an average reference, and standardizing the signals to keep them with in the same amplitude limits. The results show that the models trained with just one of the data bases only classify accurately recordings from subjects of that data base, obtaining a Kappa coefficient of 0.74 and an accuracy of 0.82 when just using grown up subjects and a Kappa of 0.77 and accuracy of 0.84 with only children. However, when testing these models on subjects of different age from the ones in the training set the level of performance decreased significantly. On the contrary, the mixed model does succeed when classifying recordings from both age ranges, obtaining an accuracy of 0.81 and a Kappa of 0.75 in the classification of a test group formed by the same number of adults and children. These results support the need to consider subjects of different ages when developing methods for the automatic detection of sleep stages, so the models obtained can adapt to a wider range of patients.Grado en Ingeniería de Tecnologías de Telecomunicació

Feature Extraction and Selection in Automatic Sleep Stage Classification

Sleep stage classification is vital for diagnosing many sleep related disorders and Polysomnography (PSG) is an important tool in this regard. The visual process of sleep stage classification is time consuming, subjective and costly. To improve the accuracy and efficiency of the sleep stage classification, researchers have been trying to develop automatic classification algorithms. The automatic sleep stage classification mainly consists of three steps: pre-processing, feature extraction and classification. In this research work, we focused on feature extraction and selection steps. The main goal of this thesis was identifying a robust and reliable feature set that can lead to efficient classification of sleep stages. For achieving this goal, three types of contributions were introduced in feature selection, feature extraction and feature vector quality enhancement. Several feature ranking and rank aggregation methods were evaluated and compared for finding the best feature set. Evaluation results indicated that the decision on the precise feature selection method depends on the system design requirements such as low computational complexity, high stability or high classification accuracy. In addition to conventional feature ranking methods, in this thesis, novel methods such as Stacked Sparse AutoEncoder (SSAE) was used for dimensionality reduction. In feature extration area, new and effective features such as distancebased features were utilized for the first time in sleep stage classification. The results showed that these features contribute positively to the classification performance. For signal quality enhancement, a loss-less EEG artefact removal algorithm was proposed. The proposed adaptive algorithm led to a significant enhancement in the overall classification accuracy

Complex networks approach for EEG signal sleep stages classification

Sleep stage scoring is a challenging task. Most of existing sleep stage classification approaches rely on analysing electroencephalography (EEG) signals in time or frequency domain. A novel technique for EEG sleep stages classification is proposed in this paper. The statistical features and the similarities of complex networks are used to classify single channel EEG signals into six sleep stages. Firstly, each EEG segment of 30 s is divided into 75 sub-segments, and then different statistical features are extracted from each sub-segment. In this paper, feature extraction is important to reduce dimensionality of EEG data and the processing time in classification stage. Secondly, each vector of the extracted features, which represents one EEG segment, is transferred into a complex network. Thirdly, the similarity properties of the com- plex networks are extracted and classified into one of the six sleep stages using a k-means classifier. For further investigation, in the statistical features extraction phase two statistical features sets are tested and ranked based on the performance of the complex networks. To investigate the classification ability of complex networks combined with k-means, the extracted statistical features were also forwarded to a k-means and a support vector machine (SVM) for comparison. We also compare the proposed method with other existing methods in the literature. The experimental results show that the proposed method attains better classification results and a reasonable execution time compared with the SVM, k-means and the other existing methods. The research results in this paper indicate that the proposed method can assist neurologists and sleep specialists in diagnosing and monitoring sleep disorders

Development of cognitive workload models to detect driving impairment

Tesi redactada en castellàDriving a vehicle is a complex activity exposed to continuous changes such as speed limits and vehicular traffic. Drivers require a high degree of concentration when performing this activity, increasing the amount of mental demand known as cognitive workload, causing vehicular accidents to the minimum negligence. In fact, human error is the leading contributing factor in over 90% of road accidents. In recent years, the subjects' cognitive workload levels while driving a vehicle have been predicted using subjective and vehicle performance tools. Other research has emphasized the use and analysis of physiological information, where electroencephalographic (EEG) signals are the most used to identify cognitive states due to their high precision. Although significant progress has been made in this area, these investigations have been based on traditional techniques or data analysis from a specific source due to the information's complexity. A new trend has been opened in the study of the internal behavior of subjects by implementing machine learning techniques to analyze information from various sources. However, there are still several challenges to face in this new line of research. This doctoral thesis presents a new model to predict the states of low and high cognitive workload of subjects when facing scenarios of driving a vehicle called GALoRSI-SVMRBF (Genetic Algorithms and Logistic Regression for the Structuring of Information-Support Vector Machine with Radial Basis Function Kernel). GALoRSI-SVMRBF is developed using machine learning algorithms based on information from EEG signals. Also, the information collected from NASA-TLX, instant online self-assessment and the error rate measure are implemented in the model. First, GALoRSI-SVMRBF proposes a new method for pattern recognition based on feature selection that combines statistical tests, genetic algorithms, and logistic regression. This method consists mainly of selecting an EEG dataset and exploring the information to identify the key features that recognize cognitive states. The selected data are defined as an index for pattern recognition and used to structure a new dataset capable of optimizing the model's learning and classification process. Second, the methodology and development of a classifier for the prediction model are presented, implementing machine learning algorithms. The classifier is developed mainly in two phases, defined as training and testing. Once the prediction model has been developed, this thesis presents the validation phase of GALoRSI-SVMRBF. The validation consists of evaluating the model's adaptability to new datasets, maintaining a high prediction rate. Finally, an analysis of the performance of GALoRSI-SVMRBF is presented. The objective is to know the model's scope and limitations, evaluating various performance metrics to find the optimal configuration for GALoRSI-SVMRBF. We found that GALoRSI-SVMRBF successfully predicts low and high cognitive workload of subjects while driving a vehicle. In general, it is observed that the model uses the information extracted from multiple EEG signals, reducing the original dataset by more than 50%, maximizing its predictive capacity, achieving a precision rate of >90% in the classification of the information. During this thesis, the experiments showed that obtaining a high percentage of prediction depends on several factors, from applying a useful collection technique data until the last step of the prediction model.La conducción de un vehículo es una actividad compleja que está expuesta a demandas que cambian continuamente por diferentes factores, tales como, el límite de velocidad, obstáculos en la vía, tráfico vehicular, entre otros. Al desempeñar esta actividad, los conductores requieren un alto grado de concentración incrementando la cantidad de demanda mental conocida como carga. En los últimos años, se han propuesto mecanismos para monitorear y/o predecir los niveles de carga cognitiva de los sujetos al conducir un vehículo, centrándose en el uso de herramientas subjetivas y de rendimiento vehicular. Otras investigaciones, han enfatizado en el uso y análisis de la información fisiológica, siendo las señales electroencefalográficas (EEG) las más utilizadas para identificar los estados cognitivos por su alta precisión. A pesar del gran avance realizado, estas investigaciones se han basado en técnicas tradicionales o en el análisis de la información proveniente de fuentes específicas para identificar el estado interno del sujeto, obteniendo modelos sobreentrenados o robustos, incrementando el tiempo de análisis afectando el desempeño del modelo. En esta tesis doctoral se presenta un nuevo modelo para predecir los estados de baja y alta carga cognitiva de los sujetos al enfrentarse a escenarios de la conducción de un vehículo denominado GALoRSI-SVMRBF (Genetic Algorithms and Logistic Regression for the Structuring of Information-Support Vector Machine with Radial Basis Function Kernel). GALoRSI-SVMRBF fue desarrollado utilizando los algoritmos de aprendizaje automático y técnicas estadísticas basado en la información proveniente de las señales EEG. Primero, GALoRSI-SVMRBF crea una base de datos extrayendo las características que serán utilizadas en el modelo a través de técnicas estadísticas. Posteriormente, propone un nuevo método para el reconocimiento de patrones basado en la selección de características que combina pruebas estadísticas, algoritmos genéticos y regresión logística. Este método consiste principalmente en seleccionar un conjunto de datos EEG y explorar la combinación de la información para identificar las características claves que contribuyan al reconocimiento de dos estados cognitivos. Después, la información seleccionada es definida como un índice para el reconocimiento de patrones y utilizada para estructurar un nuevo conjunto de datos que soporta información de uno o múltiples canales para optimizar el proceso de aprendizaje y clasificación del modelo. Por último, es desarrollado el clasificador del modelo de predicciones el cual consiste en dos etapas definidas como entrenamiento y prueba. Nosotros encontramos que GALoRSI-SVMRBF predice de manera exitosa la carga cognitiva baja y alta de los sujetos durante la conducción de un vehículo. En general, se observó que el modelo utiliza la información extraída de una o múltiples señales EEG y logrando una tasa de precisión >90% en la clasificación de la informaciónPostprint (published version

Development of electroencephalogram (EEG) signals classification techniques

Electroencephalography (EEG) is one of the most important signals recorded from humans. It can assist scientists and experts to understand the most complex part of the human body, the brain. Thus, analysing EEG signals is the most preponderant process to the problem of extracting significant information from brain dynamics. It plays a prominent role in brain studies. The EEG data are very important for diagnosing a variety of brain disorders, such as epilepsy, sleep problems, and also assisting disability patients to interact with their environment through brain computer interface (BCI). However, the EEG signals contain a huge amount of information about the brain’s activities. But the analysis and classification of these kinds of signals is still restricted. In addition, the manual examination of these signals for diagnosing related diseases is time consuming and sometimes does not work accurately. Several studies have attempted to develop different analysis and classification techniques to categorise the EEG recordings. The analysis of EEG recordings can lead to a better understanding of the cognitive process. It is used to extract the important features and reduce the dimensions of EEG data. In the classification process, machine learning algorithms are used to detect the particular class of EEG signal based on its extracted features. The performance of these algorithms, in which the class membership of the input signal is determined, can then be used to infer what event in the real-world process occurred to produce the input signal. The classification procedure has the potential to assist experts to diagnose the related brain disorders. To evaluate and diagnose neurological disorders properly, it is necessary to develop new automatic classification techniques. These techniques will help to classify different EEG signals and determine whether a person is in a good health or not. This project aims to develop new techniques to enhance the analysis and classification of different categories of EEG data. A simple random sampling (SRS) and sequential feature selection (SFS) method was developed and named the SRS_SFS method. In this method, firstly, a SRS technique was used to extract statistical features from the original EEG data in time domain. The extracted features were used as the input to a SFS algorithm for key features selection. A least square support vector machine (LS_SVM) method was then applied for EEG signals classification to evaluate the performance of the proposed approach. Secondly, a novel approach that combines optimum allocation (OA) and spectral density estimation methods was proposed to analyse EEG signals and classify an epileptic seizure. In this study, the OA technique was introduced in two levels to determine representative sample points from the EEG recordings. To reduce the dimensions of sample points and extract representative features from each OA sample segment, two power spectral density estimation methods, periodogram and autoregressive, were used. At the end, three popular machine learning methods (support vector machine (SVM), quadratic discriminant analysis, and k-nearest neighbor (k-NN)) were employed to evaluate the performance of the suggested algorithm. Additionally, a Tunable Q-factor wavelet transform (TQWT) based algorithm was developed for epileptic EEG feature extraction. The extracted features were forwarded to the bagging tree, k-NN, and SVM as classifiers to evaluate the performance of the proposed feature extraction technique. The proposed TQWT method was tested on two different EEG databases. Finally, a new classification system was presented for epileptic seizures detection in EEGs blending frequency domain with information gain (InfoGain) technique. Fast Fourier transform (FFT) or discrete wavelet transform (DWT) were applied individually to analyse EEG recording signals into frequency bands for feature extraction. To select the most important feature, the infoGain technique was employed. A LS_SVM classifier was used to evaluate the performance of this system. The research indicates that the proposed techniques are very practical and effective for classifying epileptic EEG disorders and can assist to present the most important clinical information about patients with brain disorders