4,289 research outputs found
Separation of Circulating Tokens
Self-stabilizing distributed control is often modeled by token abstractions.
A system with a single token may implement mutual exclusion; a system with
multiple tokens may ensure that immediate neighbors do not simultaneously enjoy
a privilege. For a cyber-physical system, tokens may represent physical objects
whose movement is controlled. The problem studied in this paper is to ensure
that a synchronous system with m circulating tokens has at least d distance
between tokens. This problem is first considered in a ring where d is given
whilst m and the ring size n are unknown. The protocol solving this problem can
be uniform, with all processes running the same program, or it can be
non-uniform, with some processes acting only as token relays. The protocol for
this first problem is simple, and can be expressed with Petri net formalism. A
second problem is to maximize d when m is given, and n is unknown. For the
second problem, the paper presents a non-uniform protocol with a single
corrective process.Comment: 22 pages, 7 figures, epsf and pstricks in LaTe
Advanced information processing system: The Army fault tolerant architecture conceptual study. Volume 2: Army fault tolerant architecture design and analysis
Described here is the Army Fault Tolerant Architecture (AFTA) hardware architecture and components and the operating system. The architectural and operational theory of the AFTA Fault Tolerant Data Bus is discussed. The test and maintenance strategy developed for use in fielded AFTA installations is presented. An approach to be used in reducing the probability of AFTA failure due to common mode faults is described. Analytical models for AFTA performance, reliability, availability, life cycle cost, weight, power, and volume are developed. An approach is presented for using VHSIC Hardware Description Language (VHDL) to describe and design AFTA's developmental hardware. A plan is described for verifying and validating key AFTA concepts during the Dem/Val phase. Analytical models and partial mission requirements are used to generate AFTA configurations for the TF/TA/NOE and Ground Vehicle missions
Ned-19 inhibition of parasite growth and multiplication suggests a role for NAADP mediated signalling in the asexual development of plasmodium falciparum
BACKGROUND:
Although malaria is a preventable and curable human disease, millions of people risk to be infected by the Plasmodium parasites and to develop this illness. Therefore, there is an urgent need to identify new anti-malarial drugs. Ca2+ signalling regulates different processes in the life cycle of Plasmodium falciparum, representing a suitable target for the development of new drugs.
RESULTS:
This study investigated for the first time the effect of a highly specific inhibitor of nicotinic acid adenine dinucleotide phosphate (NAADP)-induced Ca2+ release (Ned-19) on P. falciparum, revealing the inhibitory effect of this compound on the blood stage development of this parasite. Ned-19 inhibits both the transition of the parasite from the early to the late trophozoite stage and the ability of the late trophozoite to develop to the multinucleated schizont stage. In addition, Ned-19 affects spontaneous intracellular Ca2+ oscillations in ring and trophozoite stage parasites, suggesting that the observed inhibitory effects may be associated to regulation of intracellular Ca2+ levels.
CONCLUSIONS:
This study highlights the inhibitory effect of Ned-19 on progression of the asexual life cycle of P. falciparum. The observation that Ned-19 inhibits spontaneous Ca2+ oscillations suggests a potential role of NAADP in regulating Ca2+ signalling of P. falciparum
LightBox: Full-stack Protected Stateful Middlebox at Lightning Speed
Running off-site software middleboxes at third-party service providers has
been a popular practice. However, routing large volumes of raw traffic, which
may carry sensitive information, to a remote site for processing raises severe
security concerns. Prior solutions often abstract away important factors
pertinent to real-world deployment. In particular, they overlook the
significance of metadata protection and stateful processing. Unprotected
traffic metadata like low-level headers, size and count, can be exploited to
learn supposedly encrypted application contents. Meanwhile, tracking the states
of 100,000s of flows concurrently is often indispensable in production-level
middleboxes deployed at real networks.
We present LightBox, the first system that can drive off-site middleboxes at
near-native speed with stateful processing and the most comprehensive
protection to date. Built upon commodity trusted hardware, Intel SGX, LightBox
is the product of our systematic investigation of how to overcome the inherent
limitations of secure enclaves using domain knowledge and customization. First,
we introduce an elegant virtual network interface that allows convenient access
to fully protected packets at line rate without leaving the enclave, as if from
the trusted source network. Second, we provide complete flow state management
for efficient stateful processing, by tailoring a set of data structures and
algorithms optimized for the highly constrained enclave space. Extensive
evaluations demonstrate that LightBox, with all security benefits, can achieve
10Gbps packet I/O, and that with case studies on three stateful middleboxes, it
can operate at near-native speed.Comment: Accepted at ACM CCS 201
RTXP : A Localized Real-Time Mac-Routing Protocol for Wireless Sensor Networks
Protocols developed during the last years for Wireless Sensor Networks (WSNs)
are mainly focused on energy efficiency and autonomous mechanisms (e.g.
self-organization, self-configuration, etc). Nevertheless, with new WSN
applications, appear new QoS requirements such as time constraints. Real-time
applications require the packets to be delivered before a known time bound
which depends on the application requirements. We particularly focus on
applications which consist in alarms sent to the sink node. We propose
Real-Time X-layer Protocol (RTXP), a real-time communication protocol. To the
best of our knowledge, RTXP is the first MAC and routing real-time
communication protocol that is not centralized, but instead relies only on
local information. The solution is cross-layer (X-layer) because it allows to
control the delays due to MAC and Routing layers interactions. RTXP uses a
suited hop-count-based Virtual Coordinate System which allows deterministic
medium access and forwarder selection. In this paper we describe the protocol
mechanisms. We give theoretical bound on the end-to-end delay and the capacity
of the protocol. Intensive simulation results confirm the theoretical
predictions and allow to compare with a real-time centralized solution. RTXP is
also simulated under harsh radio channel, in this case the radio link
introduces probabilistic behavior. Nevertheless, we show that RTXP it performs
better than a non-deterministic solution. It thus advocates for the usefulness
of designing real-time (deterministic) protocols even for highly unreliable
networks such as WSNs
Space Shuttle/TDRSS communication and tracking systems analysis
In order to evaluate the technical and operational problem areas and provide a recommendation, the enhancements to the Tracking and Data Delay Satellite System (TDRSS) and Shuttle must be evaluated through simulation and analysis. These enhancement techniques must first be characterized, then modeled mathematically, and finally updated into LinCsim (analytical simulation package). The LinCsim package can then be used as an evaluation tool. Three areas of potential enhancements were identified: shuttle payload accommodations, TDRSS SSA and KSA services, and shuttle tracking system and navigation sensors. Recommendations for each area were discussed
Spacelab system analysis: A study of communications systems for advanced launch systems
An analysis of the required performance of internal avionics data bases for future launch vehicles is presented. Suitable local area networks that can service these requirements are determined
Virtual Machine Support for Many-Core Architectures: Decoupling Abstract from Concrete Concurrency Models
The upcoming many-core architectures require software developers to exploit
concurrency to utilize available computational power. Today's high-level
language virtual machines (VMs), which are a cornerstone of software
development, do not provide sufficient abstraction for concurrency concepts. We
analyze concrete and abstract concurrency models and identify the challenges
they impose for VMs. To provide sufficient concurrency support in VMs, we
propose to integrate concurrency operations into VM instruction sets.
Since there will always be VMs optimized for special purposes, our goal is to
develop a methodology to design instruction sets with concurrency support.
Therefore, we also propose a list of trade-offs that have to be investigated to
advise the design of such instruction sets.
As a first experiment, we implemented one instruction set extension for
shared memory and one for non-shared memory concurrency. From our experimental
results, we derived a list of requirements for a full-grown experimental
environment for further research
Spacelab system analysis: A study of the Marshall Avionics System Testbed (MAST)
An analysis of the Marshall Avionics Systems Testbed (MAST) communications requirements is presented. The average offered load for typical nodes is estimated. Suitable local area networks are determined
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