25 Desafíos de la Modelación de Procesos Semánticos

Process modeling has become an essential part of many organizations for documenting, analyzing and redesigning their business operations and to support them with suitable information systems. In order to serve this purpose, it is important for process models to be well grounded in for- mal and precise semantics. While behavioural semantics of process models are well understood, there is a considerable gap of research into the semantic aspects of their text labels and natural lan- guage descriptions. The aim of this paper is to make this research gap more transparent. To this end, we clarify the role of textual content in process models and the challenges that are associated with the interpretation, analysis, and improvement of their natural language parts. More specifically, we discuss particular use cases of semantic process modeling to identify 25 challenges. For each cha- llenge, we identify prior research and discuss directions for addressing themEl modelado de procesos se ha convertido en una parte esencial de muchas organizaciones para documentar, analizar, y rediseñar sus operaciones de negocios y apoyarlos con información apropiada. Para cumplir este fin, es importante para estos que estén completos dentro de una semántica formal y precisa. Mientras la semántica del comportamiento del modelado de procesos se entiende bien, hay una considerable laguna en la investigación entre los aspectos semánticos de sus rótulos textuales, y las descripciones en lenguaje natural. El objetivo de este artículo es hacer esta laguna en la investigación más transparente. Con este fin, clarificamos el papel del contenido textual en los modelos de proceso, y los retos relacionados con la interpretación, el análisis, y desarrollo de sus partes en lenguaje natural. De forma más específica, debatimos los casos particulares del uso del modelado de procesos semánticos para identificar 25 retos. Para cada reto, identificamos antes de la investigación y debatimos las direcciones para dirigirnos a ellos

25 Challenges of Semantic Process Modeling

Process modeling has become an essential part of many organizations for documenting, analyzing and redesigning their business operations and to support them with suitable information systems. In order to serve this purpose, it is important for process models to be well grounded in formal and precise semantics. While behavioural semantics of process models are well understood, there is a considerable gap of research into the semantic aspects of their text labels and natural language descriptions. The aim of this paper is to make this research gap more transparent. To this end, we clarify the role of textual content in process models and the challenges that are associated with the interpretation, analysis, and improvement of their natural language parts. More specifically, we discuss particular use cases of semantic process modeling to identify 25 challenges. For each challenge, we identify prior research and discuss directions for addressing them

Autonomic nervous system biomarkers from multi-modal and model-based signal processing in mental health and illness

Esta tesis se centra en técnicas de procesado multimodal y basado en modelos de señales para derivar parámetros fisiológicos, es decir, biomarcadores, relacionados con el sistema nervioso autónomo (ANS). El desarrollo de nuevos métodos para derivar biomarcadores de ANS no invasivos en la salud y la enfermedad mental ofrece la posibilidad de mejorar la evaluación del estrés y la monitorización de la depresión. Para este fin, el presente documento se estructura en tres partes principales. En la Parte I, se proporciona unaintroducción a la salud y la enfermedad mental (Cap. 1). Además, se presenta un marco teórico para investigar la etiología de los trastornos mentales y el papel del estrés en la enfermedad mental (Cap. 2). También se destaca la importancia de los biomarcadores no invasivos para la evaluación del ANS, prestando especial atención en la depresión clínica (Cap. 3, 4). En la Parte II, se proporciona el marco metodológico para derivar biomarcadores del ANS. Las técnicas de procesado de señales incluyen el análisis conjunto de la variabilidad del rítmo cardíaco (HRV) y la señal respiratoria (Cap. 6), técnicas novedosas para derivar la señal respiratoria del electrocardiograma (ECG) (Cap. 7) y un análisis robusto que se basa en modelar la forma de ondas del pulso del fotopletismograma (PPG) (Ch. 8). En la Parte III, los biomarcadores del ANS se evalúan en la quantificacióndel estrés (Cap. 9) y en la monitorización de la depresión (Ch. 10).Parte I: La salud mental no solo está relacionada con ese estado positivo de bienestar, en el que un individuo puede enfrentar a las situaciones estresantes de la vida, sino también con la ausencia de enfermedad mental. La enfermedad o trastorno mental se puede definir como un trastorno emocional, cognitivo o conductual que causa un deterioro funcional sustancial en una o más actividades importantes de la vida. Los trastornos mentales más comunes, que muchas veces coexisten, son la ansiedad y el trastorno depresivo mayor (MDD). La enfermedad mental tiene un impacto negativo en la calidad de vida, ya que se asocia con pérdidas considerables en la salud y el funcionamiento, y aumenta ignificativamente el riesgo de una persona de padecer enfermedades ardiovasculares.Un instigador común que subyace a la comorbilidad entre el MDD, la patologíacardiovascular y la ansiedad es el estrés mental. El estrés es común en nuestra vida de rítmo rapido e influye en nuestra salud mental. A corto plazo, ANS controla la respuesta cardiovascular a estímulos estresantes. La regulación de parámetros fisiológicos, como el rítmo cardíaco, la frecuencia respiratoria y la presión arterial, permite que el organismo responda a cambios repentinos en el entorno. Sin embargo, la adaptación fisiológica a un fenómeno ambiental que ocurre regularmente altera los sistemas biológicos involucrados en la respuesta al estrés. Las alteraciones neurobiológicas en el cerebro pueden alterar lafunción del ANS. La disfunción del ANS y los cambios cerebrales estructurales tienen un impacto negativo en los procesos cognitivos, emocionales y conductuales, lo que conduce al desarrollo de una enfermedad mental.Parte II: El desarrollo de métodos novedosos para derivar biomarcadores del ANS no invasivos ofrece la posibilidad de mejorar la evaluacón del estrés en individuos sanos y la disfunción del ANS en pacientes con MDD. El análisis conjunto de varias bioseñales (enfoquemultimodal) permite la cuantificación de interacciones entre sistemas biológicos asociados con ANS, mientras que el modelado de bioseãles y el análisis posterior de los parámetros del modelo (enfoque basado en modelos) permite la cuantificación robusta de cambios en mecanismos fisiológicos relacionados con el ANS. Un método novedoso, quetiene en cuenta los fenómenos de acoplo de fase y frecuencia entre la respiración y las señales de HRV para evaluar el acoplo cardiorrespiratorio no lineal cuadrático se propone en el Cap. 6.3. En el Cap. 7 se proponen nuevas técnicas paramejorar lamonitorización de la respiración. En el Cap. 8, para aumentar la robustez de algunas medidas morfológicas que reflejan cambios en el tonno arterial, se considera el modelado del pulso PPG como una onda principal superpuesta con varias ondas reflejadas.Parte III: Los biomarcadores del ANS se evalúan en la cuantificación de diferentes tipos de estrés, ya sea fisiológico o psicológico, en individuos sanos, y luego, en la monitorización de la depresión. En presencia de estrés mental (Cap. 9.1), inducido por tareas cognitivas, los sujetos sanos muestran un incremento en la frecuencia respiratoria y un mayor número de interacciones no lineales entre la respiración y la seãl de HRV. Esto podría estar asociado con una activación simpática, pero también con una respiración menos regular. En presencia de estrés hemodinámico (Cap. 9.2), inducido por un cambio postural, los sujetos sanos muestran una reducción en el acoplo cardiorrespiratoriono lineal cuadrático, que podría estar relacionado con una retracción vagal. En presencia de estrés térmico (Cap. 9.3), inducido por la exposición a emperaturas ambientales elevadas, los sujetos sanos muestran un aumento del equilibrio simpatovagal. Esto demuestra que los biomarcadores ANS son capaces de evaluar diferentes tipos de estrés y pueden explorarse más en el contexto de la monitorización de la depresión. En el Cap. 10, se evalúan las diferencias en la función del ANS entre elMDD y los sujetos sanos durante un protocolo de estrés mental, no solo con los valores brutos de los biomarcadores del ANS, sino también con los índices de reactividad autónoma, que reflejan la capacidad deun individuo para afrontar con una situación desafiante. Los resultados muestran que la depresión se asocia con un desequilibrio autonómico, que se caracteriza por una mayor actividad simpática y una reducción de la distensibilidad arterial. Los índices de reactividad autónoma cuantificados por cambios, entre etapas de estrés y de recuperación, en los sustitutos de la rigidez arterial, como la pérdida de amplitud de PPG en las ondas reflejadas, muestran el mejor rendimiento en términos de correlación con el grado de la depresión, con un coeficiente de correlación r = −0.5. La correlación negativa implicaque un mayor grado de depresión se asocia con una disminución de la reactividadautónoma. El poder discriminativo de los biomarcadores del ANS se aprecia también por su alto rendimiento diagnóstico para clasificar a los sujetos como MDD o sanos, con una precisión de 80.0%. Por lo tanto, se puede concluir que los biomarcadores del ANS pueden usarse para evaluar el estrés y que la distensibilidad arterial deteriorada podría constituir un biomarcador de salud mental útil en el seguimiento de la depresión.This dissertation is focused on multi-modal and model-based signal processing techniques for deriving physiological parameters, i.e. biomarkers, related to the autonomic nervous system (ANS). The development of novel approaches for deriving noninvasive ANS biomarkers in mental health and illness offers the possibility to improve the assessment of stress and the monitoring of depression. For this purpose, the present document is structured in three main parts. In Part I, an introduction to mental health and illness is provided (Ch. 1). Moreover, a theoretical framework for investigating the etiology of mental disorders and the role of stress in mental illness is presented (Ch. 2). The importance of noninvasive biomarkers for ANS assessment, paying particular attention in clinical depression, is also highlighted (Ch. 3, 4). In Part II, themethodological framework for deriving ANS biomarkers is provided. Signal processing techniques include the joint analysis of heart rate variability (HRV) and respiratory signals (Ch. 6), novel techniques for deriving the respiratory signal from electrocardiogram (ECG) (Ch. 7), and a robust photoplethysmogram(PPG)waveform analysis based on amodel-based approach (Ch. 8). In Part III, ANS biomarkers are evaluated in stress assessment (Ch. 9) and in the monitoring of depression (Ch. 10). Part I:Mental health is not only related to that positive state ofwell-being, inwhich an individual can cope with the normal stresses of life, but also to the absence of mental illness. Mental illness or disorder can be defined as an emotional, cognitive, or behavioural disturbance that causes substantial functional impairment in one or more major life activities. The most common mental disorders, which are often co-occurring, are anxiety and major depressive disorder (MDD). Mental illness has a negative impact on the quality of life, since it is associated with considerable losses in health and functioning, and increases significantly a person’s risk for cardiovascular diseases. A common instigator underlying the co-morbidity between MDD, cardiovascular pathology, and anxiety is mental stress. Stress is common in our fast-paced society and strongly influences our mental health. In the short term, ANS controls the cardiovascular response to stressful stimuli. Regulation of physiological parameters, such as heart rate, respiratory rate, and blood pressure, allows the organism to respond to sudden changes in the environment. However, physiological adaptation to a regularly occurring environmental phenomenon alters biological systems involved in stress response. Neurobiological alterations in the brain can disrupt the function of the ANS. ANS dysfunction and structural brain changes have a negative impact on cognitive, emotional, and behavioral processes, thereby leading to development of mental illness. Part II: The development of novel approaches for deriving noninvasive ANS biomarkers offers the possibility to improve the assessment of stress in healthy individuals and ANS dysfunction in MDD patients. Joint analysis of various biosignals (multi-modal approach) allows for the quantification of interactions among biological systems associated with ANS, while the modeling of biosignals and subsequent analysis of the model’s parameters (model-based approach) allows for the robust quantification of changes in physiological mechanisms related to the ANS. A novel method, which takes into account both phase and frequency locking phenomena between respiration and HRV signals, for assessing quadratic nonlinear cardiorespiratory coupling is proposed in Ch. 6.3. Novel techniques for improving the monitoring of respiration are proposed in Ch. 7. In Ch. 8, to increase the robustness for some morphological measurements reflecting arterial tone changes, the modeling of the PPG pulse as amain wave superposed with several reflected waves is considered. Part III: ANS biomarkers are evaluated in the assessment of different types of stress, either physiological or psychological, in healthy individuals, and then, in the monitoring of depression. In the presence of mental stress (Ch. 9.1), induced by cognitive tasks, healthy subjects show an increment in the respiratory rate and higher number of nonlinear interactions between respiration and HRV signal, which might be associated with a sympathetic activation, but also with a less regular breathing. In the presence of hemodynamic stress (Ch. 9.2), induced by a postural change, healthy subjects show a reduction in strength of the quadratic nonlinear cardiorespiratory coupling, whichmight be related to a vagal withdrawal. In the presence of heat stress (Ch. 9.3), induced by exposure to elevated environmental temperatures, healthy subjects show an increased sympathovagal balance. This demonstrates that ANS biomarkers are able to assess different types of stress and they can be further explored in the context of depression monitoring. In Ch. 10, differences in ANS function between MDD and healthy subjects during a mental stress protocol are assessed, not only with the raw values of ANS biomarkers but also with autonomic reactivity indices, which reflect the ability of an individual to copewith a challenging situation. Results show that depression is associated with autonomic imbalance, characterized by increased sympathetic activity and reduced arterial compliance. Autonomic reactivity indices quantified by changes, from stress to recovery, in arterial stiffness surrogates, such as the PPG amplitude loss in wave reflections, show the best performance in terms of correlation with depression severity, yielding to correlation coefficient r = −0.5. The negative correlation implies that a higher degree of depression is associated with a decreased autonomic reactivity. The discriminative power of ANS biomarkers is supported by their high diagnostic performance for classifying subjects as having MDD or not, yielding to accuracy of 80.0%. Therefore, it can be concluded that ANS biomarkers can be used for assessing stress and that impaired arterial compliance might constitute a biomarker of mental health useful in the monitoring of depression.<br /

Sustainable Smart Cities and Smart Villages Research

ca. 200 words; this text will present the book in all promotional forms (e.g. flyers). Please describe the book in straightforward and consumer-friendly terms. [There is ever more research on smart cities and new interdisciplinary approaches proposed on the study of smart cities. At the same time, problems pertinent to communities inhabiting rural areas are being addressed, as part of discussions in contigious fields of research, be it environmental studies, sociology, or agriculture. Even if rural areas and countryside communities have previously been a subject of concern for robust policy frameworks, such as the European Union’s Cohesion Policy and Common Agricultural Policy Arguably, the concept of ‘the village’ has been largely absent in the debate. As a result, when advances in sophisticated information and communication technology (ICT) led to the emergence of a rich body of research on smart cities, the application and usability of ICT in the context of a village has remained underdiscussed in the literature. Against this backdrop, this volume delivers on four objectives. It delineates the conceptual boundaries of the concept of ‘smart village’. It highlights in which ways ‘smart village’ is distinct from ‘smart city’. It examines in which ways smart cities research can enrich smart villages research. It sheds light on the smart village research agenda as it unfolds in European and global contexts.

Linguistic Refactoring of Business Process Models

In the past decades, organizations had to face numerous challenges due to intensifying globalization and internationalization, shorter innovation cycles and growing IT support for business. Business process management is seen as a comprehensive approach to align business strategy, organization, controlling, and business activities to react flexibly to market changes. For this purpose, business process models are increasingly utilized to document and redesign relevant parts of the organization's business operations. Since companies tend to have a growing number of business process models stored in a process model repository, analysis techniques are required that assess the quality of these process models in an automatic fashion. While available techniques can easily check the formal content of a process model, there are only a few techniques available that analyze the natural language content of a process model. Therefore, techniques are required that address linguistic issues caused by the actual use of natural language. In order to close this gap, this doctoral thesis explicitly targets inconsistencies caused by natural language and investigates the potential of automatically detecting and resolving them under a linguistic perspective. In particular, this doctoral thesis provides the following contributions. First, it defines a classification framework that structures existing work on process model analysis and refactoring. Second, it introduces the notion of atomicity, which implements a strict consistency condition between the formal content and the textual content of a process model. Based on an explorative investigation, we reveal several reoccurring violation patterns are not compliant with the notion of atomicity. Third, this thesis proposes an automatic refactoring technique that formalizes the identified patterns to transform a non-atomic process models into an atomic one. Fourth, this thesis defines an automatic technique for detecting and refactoring synonyms and homonyms in process models, which is eventually useful to unify the terminology used in an organization. Fifth and finally, this thesis proposes a recommendation-based refactoring approach that addresses process models suffering from incompleteness and leading to several possible interpretations. The efficiency and usefulness of the proposed techniques is further evaluated by real-world process model repositories from various industries. (author's abstract

Validierung von MultiView-basierten Prozessmodellen mit grafischen Validierungsregeln

Die Bedeutung und Verbreitung von Software wächst im betrieblichen und privaten Umfeld stetig. Das primäre Ziel bei der Verwendung von Software ist die Optimierung manueller oder bereits (teil-) automatisierter Problem- bzw. Aufgabenstellungen. Der zentrale Bezugspunkt bei der Entwicklung der Software ist die Softwarespezifikation. Diese beinhaltet im Idealfall alle für die Softwarelösung relevanten Anforderungen. Ein an Bedeutung gewinnender Bestandteil der Spezifikation sind Geschäftsprozessmodelle. Diese beschreiben dabei die Abläufe der zu entwickelnden Softwarelösung in Form von grafischen Prozessdarstellungen. Aufgrund der zunehmenden Anreicherung der Prozessmodelle mit Anforderungen und Informationen wie bspw. gesetzlichen Bestimmungen oder Details für die modellgetriebene Softwareentwicklung erwachsen aus einfachen Ablaufdarstellungen komplexe und umfangreiche Geschäftsprozessmodelle. Unabhängig davon, ob Geschäftsprozessmodelle zur reinen Spezifikation bzw. Dokumentation dienen oder für die modellgetriebene Softwareentwicklung eingesetzt werden, ist ein zentrales Ziel die Sicherstellung der inhaltlichen Korrektheit der Geschäftsprozessmodelle und damit der darin modellierten Anforderungen. In aktuellen Softwareentwicklungsprozessen werden dazu häufig manuelle Prüfverfahren eingesetzt, welche jedoch häufig sowohl zeit- als auch kostenintensiv und zudem fehleranfällig sind. Automatisierbare Verfahren benötigen allerdings formale Spezifikationssprachen. Diese werden aber aufgrund ihrer mathematisch anmutenden textuellen Darstellung im Umfeld der Geschäftsprozessmodellierung meist abgelehnt. Im Gegensatz zu textuellen Darstellungen sind grafische Repräsentationen häufig leichter verständlich und werden vor allem im Bereich der Geschäftsprozessmodellierung eher akzeptiert. Im Rahmen der Arbeit wird daher ein auf formalen grafischen Validierungsregeln basierendes Konzept zur Überprüfung der inhaltlichen Korrektheit von Geschäftsprozessmodellen vorgestellt. Das Konzept ist dabei unabhängig von der Modellierungssprache der Geschäftsprozessmodelle sowie von der Spezifikationssprache der Validierungsregeln. Zur Verbesserung der Beherrschbarkeit der zunehmend komplexen und umfangreichen Geschäftsprozessmodelle wird zudem ein als MultiVview bezeichnetes Sichtenkonzept vorgestellt. Dies dient zur Reduzierung der grafischen Komplexität und zur Zuordnung von Aufgaben- und Verantwortungsbereichen (beispielsweise Datenschutz- und Sicherheitsmodellierung) bei der Geschäftsprozessmodellierung. Das Gesamtkonzept wurde prototypisch in der Software ARIS Business Architect und als Plug-in für die Entwicklungsumgebung Eclipse realisiert. Eine Evaluation erfolgt zum einen an dem Eclipse Plug-in anhand eines Requirements Engineering Tool Evaluation Framework und zum anderen anhand von Anwendungsfällen aus dem Bereich der öffentlichen Verwaltung, der ELSTER-Steuererklärung und SAP-Referenzprozessen

New Insights into Food Fermentation

This reprint is dedicated to new insights into food fermentation. The goal of this reprint was to broaden the current knowledge on advanced approaches concerning food fermentation, gathering studies on conventional and unconventional food matrix fermentation, functional compounds obtained through fermentation, fermentations increasing quality and safety standards, as well as papers presenting innovative approaches shedding light on the microbial community that characterizes fermented foods

Annual Report of the University, 1972-1973, Volumes 1-3

At the varsity level, our teams have competed in the following sports: football, basketball, track, cross country, baseball, tennis, wrestling, swimming, golf, gymnastics and skiing. Junior varsity teams played regular schedules in football and basketball. A total of 167 athletes received major letter awards; 21 freshmen athletes were awarded numerals in basketball and football making a grand total of 188

Bio-Inspired Robotics

Modern robotic technologies have enabled robots to operate in a variety of unstructured and dynamically-changing environments, in addition to traditional structured environments. Robots have, thus, become an important element in our everyday lives. One key approach to develop such intelligent and autonomous robots is to draw inspiration from biological systems. Biological structure, mechanisms, and underlying principles have the potential to provide new ideas to support the improvement of conventional robotic designs and control. Such biological principles usually originate from animal or even plant models, for robots, which can sense, think, walk, swim, crawl, jump or even fly. Thus, it is believed that these bio-inspired methods are becoming increasingly important in the face of complex applications. Bio-inspired robotics is leading to the study of innovative structures and computing with sensory–motor coordination and learning to achieve intelligence, flexibility, stability, and adaptation for emergent robotic applications, such as manipulation, learning, and control. This Special Issue invites original papers of innovative ideas and concepts, new discoveries and improvements, and novel applications and business models relevant to the selected topics of ``Bio-Inspired Robotics''. Bio-Inspired Robotics is a broad topic and an ongoing expanding field. This Special Issue collates 30 papers that address some of the important challenges and opportunities in this broad and expanding field