A survey of multiple classifier systems as hybrid systems

A current focus of intense research in pattern classification is the combination of several classifier systems, which can be built following either the same or different models and/or datasets building approaches. These systems perform information fusion of classification decisions at different levels overcoming limitations of traditional approaches based on single classifiers. This paper presents an up-to-date survey on multiple classifier system (MCS) from the point of view of Hybrid Intelligent Systems. The article discusses major issues, such as diversity and decision fusion methods, providing a vision of the spectrum of applications that are currently being developed

Diversified Ensemble Classifiers for Highly Imbalanced Data Learning and their Application in Bioinformatics

In this dissertation, the problem of learning from highly imbalanced data is studied. Imbalance data learning is of great importance and challenge in many real applications. Dealing with a minority class normally needs new concepts, observations and solutions in order to fully understand the underlying complicated models. We try to systematically review and solve this special learning task in this dissertation.We propose a new ensemble learning framework—Diversified Ensemble Classifiers for Imbal-anced Data Learning (DECIDL), based on the advantages of existing ensemble imbalanced learning strategies. Our framework combines three learning techniques: a) ensemble learning, b) artificial example generation, and c) diversity construction by reversely data re-labeling. As a meta-learner, DECIDL utilizes general supervised learning algorithms as base learners to build an ensemble committee. We create a standard benchmark data pool, which contains 30 highly skewed sets with diverse characteristics from different domains, in order to facilitate future research on imbalance data learning. We use this benchmark pool to evaluate and compare our DECIDL framework with several ensemble learning methods, namely under-bagging, over-bagging, SMOTE-bagging, and AdaBoost. Extensive experiments suggest that our DECIDL framework is comparable with other methods. The data sets, experiments and results provide a valuable knowledge base for future research on imbalance learning. We develop a simple but effective artificial example generation method for data balancing. Two new methods DBEG-ensemble and DECIDL-DBEG are then designed to improve the power of imbalance learning. Experiments show that these two methods are comparable to the state-of-the-art methods, e.g., GSVM-RU and SMOTE-bagging. Furthermore, we investigate learning on imbalanced data from a new angle—active learning. By combining active learning with the DECIDL framework, we show that the newly designed Active-DECIDL method is very effective for imbalance learning, suggesting the DECIDL framework is very robust and flexible.Lastly, we apply the proposed learning methods to a real-world bioinformatics problem—protein methylation prediction. Extensive computational results show that the DECIDL method does perform very well for the imbalanced data mining task. Importantly, the experimental results have confirmed our new contributions on this particular data learning problem

Methods to Improve the Prediction Accuracy and Performance of Ensemble Models

The application of ensemble predictive models has been an important research area in predicting medical diagnostics, engineering diagnostics, and other related smart devices and related technologies. Most of the current predictive models are complex and not reliable despite numerous efforts in the past by the research community. The performance accuracy of the predictive models have not always been realised due to many factors such as complexity and class imbalance. Therefore there is a need to improve the predictive accuracy of current ensemble models and to enhance their applications and reliability and non-visual predictive tools. The research work presented in this thesis has adopted a pragmatic phased approach to propose and develop new ensemble models using multiple methods and validated the methods through rigorous testing and implementation in different phases. The first phase comprises of empirical investigations on standalone and ensemble algorithms that were carried out to ascertain their performance effects on complexity and simplicity of the classifiers. The second phase comprises of an improved ensemble model based on the integration of Extended Kalman Filter (EKF), Radial Basis Function Network (RBFN) and AdaBoost algorithms. The third phase comprises of an extended model based on early stop concepts, AdaBoost algorithm, and statistical performance of the training samples to minimize overfitting performance of the proposed model. The fourth phase comprises of an enhanced analytical multivariate logistic regression predictive model developed to minimize the complexity and improve prediction accuracy of logistic regression model. To facilitate the practical application of the proposed models; an ensemble non-invasive analytical tool is proposed and developed. The tool links the gap between theoretical concepts and practical application of theories to predict breast cancer survivability. The empirical findings suggested that: (1) increasing the complexity and topology of algorithms does not necessarily lead to a better algorithmic performance, (2) boosting by resampling performs slightly better than boosting by reweighting, (3) the prediction accuracy of the proposed ensemble EKF-RBFN-AdaBoost model performed better than several established ensemble models, (4) the proposed early stopped model converges faster and minimizes overfitting better compare with other models, (5) the proposed multivariate logistic regression concept minimizes the complexity models (6) the performance of the proposed analytical non-invasive tool performed comparatively better than many of the benchmark analytical tools used in predicting breast cancers and diabetics ailments. The research contributions to ensemble practice are: (1) the integration and development of EKF, RBFN and AdaBoost algorithms as an ensemble model, (2) the development and validation of ensemble model based on early stop concepts, AdaBoost, and statistical concepts of the training samples, (3) the development and validation of predictive logistic regression model based on breast cancer, and (4) the development and validation of a non-invasive breast cancer analytic tools based on the proposed and developed predictive models in this thesis. To validate prediction accuracy of ensemble models, in this thesis the proposed models were applied in modelling breast cancer survivability and diabetics’ diagnostic tasks. In comparison with other established models the simulation results of the models showed improved predictive accuracy. The research outlines the benefits of the proposed models, whilst proposes new directions for future work that could further extend and improve the proposed models discussed in this thesis

Individual and ensemble functional link neural networks for data classification

This study investigated the Functional Link Neural Network (FLNN) for solving data classification problems. FLNN based models were developed using evolutionary methods as well as ensemble methods. The outcomes of the experiments covering benchmark classification problems, positively demonstrated the efficacy of the proposed models for undertaking data classification problems

Dynamic protein classification: Adaptive models based on incremental learning strategies

Abstract One of the major problems in computational biology is the inability of existing classification models to incorporate expanding and new domain knowledge. This problem of static classification models is addressed in this thesis by the introduction of incremental learning for problems in bioinformatics. The tools which have been developed are applied to the problem of classifying proteins into a number of primary and putative families. The importance of this type of classification is of particular relevance due to its role in drug discovery programs and the benefit it lends to this process in terms of cost and time saving. As a secondary problem, multi–class classification is also addressed. The standard approach to protein family classification is based on the creation of committees of binary classifiers. This one-vs-all approach is not ideal, and the classification systems presented here consists of classifiers that are able to do all-vs-all classification. Two incremental learning techniques are presented. The first is a novel algorithm based on the fuzzy ARTMAP classifier and an evolutionary strategy. The second technique applies the incremental learning algorithm Learn++. The two systems are tested using three datasets: data from the Structural Classification of Proteins (SCOP) database, G-Protein Coupled Receptors (GPCR) database and Enzymes from the Protein Data Bank. The results show that both techniques are comparable with each other, giving classification abilities which are comparable to that of the single batch trained classifiers, with the added ability of incremental learning. Both the techniques are shown to be useful to the problem of protein family classification, but these techniques are applicable to problems outside this area, with applications in proteomics including the predictions of functions, secondary and tertiary structures, and applications in genomics such as promoter and splice site predictions and classification of gene microarrays